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The map label for this gene is sodB [H]

Identifier: 110633218

GI number: 110633218

Start: 955608

End: 956210

Strand: Direct

Name: sodB [H]

Synonym: Meso_0861

Alternate gene names: 110633218

Gene position: 955608-956210 (Clockwise)

Preceding gene: 110633215

Following gene: 110633221

Centisome position: 21.66

GC content: 56.88

Gene sequence:

>603_bases
ATGGCCTTTGAACTGCCGGACCTGCCCTACGACTATGAAGCTTTGCAGCCTTACATGTCGAAGGAAACGCTGGAATTCCA
TCACGACAAGCATCACAAGGCCTATGTGGACACAGGCAACAAGCTTGCGGCCGAAGCCGGGCTCGACAACCTCTCGGTGG
AGGAAATCGTCAAGCAGTCCTATGGCAAGAATCAGCCGCTCTTCAACAATGCCGGCCAGCATTTCAACCACGTTCATTTC
TGGAAATGGATGAAGAAGGGTGGCGGCGGCAAGAGCCTGCCCGGCGCGCTGCAGACGGCGATCGACAGCGATCTCGGCGG
CTATGACAAGTTCCGCAACGATTTCGTGCAGGCCGGCATGACGCAGTTCGGCTCTGGCTGGGCATGGATTGCGGTCAAGA
ACGGCAAGCTCGAAATCATGAAGACGCCGAATGGCGAGAACCCGCTGGTCCATGGCGGCGCGCCGATTCTCGGTGTCGAT
GTCTGGGAGCACTCCTATTACATCGATTACCGCAACGCCCGGCAGAAATATCTGGAAGCCTTCGTCGATAATCTCGTCAA
CTGGGACTACGTCCTGGAGCTTTACGAAAAGGCGCGCGGCTGA

Upstream 100 bases:

>100_bases
GCCGCCTGTTAAGAGATCATCAGGGAACGGTTGCCAAAACGGGCTGCCCGCCCCATCTGCGGTTTGTGGATTTTCAACCA
CCTTTCTGAGGGAGACGAAT

Downstream 100 bases:

>100_bases
ACGGCTGAAAGTCTATGAAAAAGAGCCCGGCTTTCAGCCGGGTTTTCTTTTTAGGGGAGTAGGGCAGTAGGATGAATGTC
TCTTGCCCTTGCTTTTGGTG

Product: manganese and iron superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MAFELPDLPYDYEALQPYMSKETLEFHHDKHHKAYVDTGNKLAAEAGLDNLSVEEIVKQSYGKNQPLFNNAGQHFNHVHF
WKWMKKGGGGKSLPGALQTAIDSDLGGYDKFRNDFVQAGMTQFGSGWAWIAVKNGKLEIMKTPNGENPLVHGGAPILGVD
VWEHSYYIDYRNARQKYLEAFVDNLVNWDYVLELYEKARG

Sequences:

>Translated_200_residues
MAFELPDLPYDYEALQPYMSKETLEFHHDKHHKAYVDTGNKLAAEAGLDNLSVEEIVKQSYGKNQPLFNNAGQHFNHVHF
WKWMKKGGGGKSLPGALQTAIDSDLGGYDKFRNDFVQAGMTQFGSGWAWIAVKNGKLEIMKTPNGENPLVHGGAPILGVD
VWEHSYYIDYRNARQKYLEAFVDNLVNWDYVLELYEKARG
>Mature_199_residues
AFELPDLPYDYEALQPYMSKETLEFHHDKHHKAYVDTGNKLAAEAGLDNLSVEEIVKQSYGKNQPLFNNAGQHFNHVHFW
KWMKKGGGGKSLPGALQTAIDSDLGGYDKFRNDFVQAGMTQFGSGWAWIAVKNGKLEIMKTPNGENPLVHGGAPILGVDV
WEHSYYIDYRNARQKYLEAFVDNLVNWDYVLELYEKARG

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=200, Percent_Identity=39.5, Blast_Score=140, Evalue=9e-34,
Organism=Homo sapiens, GI67782305, Length=200, Percent_Identity=39.5, Blast_Score=140, Evalue=9e-34,
Organism=Homo sapiens, GI67782309, Length=200, Percent_Identity=35, Blast_Score=113, Evalue=9e-26,
Organism=Escherichia coli, GI1787946, Length=193, Percent_Identity=46.1139896373057, Blast_Score=170, Evalue=6e-44,
Organism=Escherichia coli, GI1790342, Length=200, Percent_Identity=43.5, Blast_Score=168, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17506561, Length=199, Percent_Identity=37.6884422110553, Blast_Score=130, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17569479, Length=196, Percent_Identity=35.2040816326531, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321796, Length=200, Percent_Identity=36, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136812, Length=200, Percent_Identity=36.5, Blast_Score=128, Evalue=3e-30,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 22743; Mature: 22612

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFELPDLPYDYEALQPYMSKETLEFHHDKHHKAYVDTGNKLAAEAGLDNLSVEEIVKQS
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCCCCCCHHHHHHHH
YGKNQPLFNNAGQHFNHVHFWKWMKKGGGGKSLPGALQTAIDSDLGGYDKFRNDFVQAGM
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
TQFGSGWAWIAVKNGKLEIMKTPNGENPLVHGGAPILGVDVWEHSYYIDYRNARQKYLEA
HHHCCCEEEEEEECCEEEEEECCCCCCCEEECCCCEEEEEEECCEEEEEHHHHHHHHHHH
FVDNLVNWDYVLELYEKARG
HHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AFELPDLPYDYEALQPYMSKETLEFHHDKHHKAYVDTGNKLAAEAGLDNLSVEEIVKQS
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCCCCCCHHHHHHHH
YGKNQPLFNNAGQHFNHVHFWKWMKKGGGGKSLPGALQTAIDSDLGGYDKFRNDFVQAGM
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
TQFGSGWAWIAVKNGKLEIMKTPNGENPLVHGGAPILGVDVWEHSYYIDYRNARQKYLEA
HHHCCCEEEEEEECCEEEEEECCCCCCCEEECCCCEEEEEEECCEEEEEHHHHHHHHHHH
FVDNLVNWDYVLELYEKARG
HHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419947; 11481430 [H]