Click here to switch to the map view.

The map label for this gene is cysD

Identifier: 110633190

GI number: 110633190

Start: 924079

End: 924984

Strand: Direct

Name: cysD

Synonym: Meso_0833

Alternate gene names: 110633190

Gene position: 924079-924984 (Clockwise)

Preceding gene: 110633189

Following gene: 110633191

Centisome position: 20.94

GC content: 58.83

Gene sequence:

>906_bases
ATGACGGCAAACCTGACGCATCTTCAGCGCCTTGAAGCTGAATCAATCCACATCATGCGAGGGGTGGCGGCGAATTTTTC
CAAGCCGGTGATGCTTTACTCCATCGGTAAGGATTCGTCCGTTCTGCTGCATCTGGCGATGAAAGCCTTTTACCCGGCCA
AGCCTCCCTTTCCCTTCCTCCATGTCGACACGACGTGGAAATTCAGGGAGATGATTGAATTTCGCGACCGCATGGCGGCC
GAACTGGGTTTCGATCTTCTGGTGCATATCAACGAGGAGGGCGTGCGCGACGGCATCAACCCGTTCGACCACGGCTCCAA
CGTGCACACGCATATTATGAAGACCGTGGCGCTGCGCCAGGCGCTGGACAAATATGGATTCGATGCGGCGTTCGGCGGCG
CGCGCCGCGACGAGGAGAAGAGCCGCGCCAAGGAGCGCGTCTTTTCCTTCCGGACTGCCAGCCACACCTGGGACCCGAAG
AACCAGCGGCCGGAGATGTGGAAAATCTACAATACCCGCGTCGCGCAGGGTGAATCGATCCGCGTCTTCCCGCTCTCCAA
CTGGACCGAGCTCGATATTTGGCAATACATTCTGCAGGAGGGGATTCCGATTGTGCCGCTATACTTCGCGAAGAAGCGGC
CGGTCGTGAATCGTGGGGGCATGACGATCATGGTCGATGATGACCGTATGAAGCTTCTTCCCGGCGAGACCGTCGAGGAG
CGCATGGTGCGCTTCCGCACGCTGGGCTGCTATCCACTGACGGGGGCCATCGATTCCTGCGCCGCGACGCTGGAGGATAT
TGTCTCTGAAATGCTGACGGCTCGCACCTCGGAGCGTCAGGGCCGTCTCATCGACCGCGATGAGGCAGGCTCGATGGAAA
AGAAGAAGCGCGAGGGGTATTTCTGA

Upstream 100 bases:

>100_bases
GTTTTGGCCACCTTGAGGGGCCTGTTGCTGCAGTGCTATTGCCACTGAAACGGCGTTTTATGGCGAGCGCTGGACAACAC
ACAAGAAGGTCATTGCTCAG

Downstream 100 bases:

>100_bases
TGCTGAGCTCCAACGCCGCGGCCGCGGTCGCAGACGCCGAGACGGAAACCGCCGATATTCGCGCTTATCTCTCCTCGCAG
GAGAGAAAGACCTTGCTGCG

Product: sulfate adenylyltransferase subunit 2

Products: NA

Alternate protein names: ATP-sulfurylase small subunit; Sulfate adenylate transferase; SAT

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTANLTHLQRLEAESIHIMRGVAANFSKPVMLYSIGKDSSVLLHLAMKAFYPAKPPFPFLHVDTTWKFREMIEFRDRMAA
ELGFDLLVHINEEGVRDGINPFDHGSNVHTHIMKTVALRQALDKYGFDAAFGGARRDEEKSRAKERVFSFRTASHTWDPK
NQRPEMWKIYNTRVAQGESIRVFPLSNWTELDIWQYILQEGIPIVPLYFAKKRPVVNRGGMTIMVDDDRMKLLPGETVEE
RMVRFRTLGCYPLTGAIDSCAATLEDIVSEMLTARTSERQGRLIDRDEAGSMEKKKREGYF

Sequences:

>Translated_301_residues
MTANLTHLQRLEAESIHIMRGVAANFSKPVMLYSIGKDSSVLLHLAMKAFYPAKPPFPFLHVDTTWKFREMIEFRDRMAA
ELGFDLLVHINEEGVRDGINPFDHGSNVHTHIMKTVALRQALDKYGFDAAFGGARRDEEKSRAKERVFSFRTASHTWDPK
NQRPEMWKIYNTRVAQGESIRVFPLSNWTELDIWQYILQEGIPIVPLYFAKKRPVVNRGGMTIMVDDDRMKLLPGETVEE
RMVRFRTLGCYPLTGAIDSCAATLEDIVSEMLTARTSERQGRLIDRDEAGSMEKKKREGYF
>Mature_300_residues
TANLTHLQRLEAESIHIMRGVAANFSKPVMLYSIGKDSSVLLHLAMKAFYPAKPPFPFLHVDTTWKFREMIEFRDRMAAE
LGFDLLVHINEEGVRDGINPFDHGSNVHTHIMKTVALRQALDKYGFDAAFGGARRDEEKSRAKERVFSFRTASHTWDPKN
QRPEMWKIYNTRVAQGESIRVFPLSNWTELDIWQYILQEGIPIVPLYFAKKRPVVNRGGMTIMVDDDRMKLLPGETVEER
MVRFRTLGCYPLTGAIDSCAATLEDIVSEMLTARTSERQGRLIDRDEAGSMEKKKREGYF

Specific function: First step in the sulfate activation pathway. This reaction occurs early in the reductive branch of the cysteine biosynthetic pathway. [C]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysD subfamily

Homologues:

Organism=Escherichia coli, GI1789109, Length=297, Percent_Identity=71.7171717171717, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSD_MESSB (Q11K42)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673398.1
- ProteinModelPortal:   Q11K42
- SMR:   Q11K42
- STRING:   Q11K42
- GeneID:   4179666
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0833
- NMPDR:   fig|266779.1.peg.4270
- eggNOG:   COG0175
- HOGENOM:   HBG758022
- OMA:   HYGFDAA
- PhylomeDB:   Q11K42
- ProtClustDB:   PRK05253
- BioCyc:   MSP266779:MESO_0833-MONOMER
- HAMAP:   MF_00064
- InterPro:   IPR002500
- InterPro:   IPR014729
- InterPro:   IPR011784
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF002936
- TIGRFAMs:   TIGR02039

Pfam domain/function: PF01507 PAPS_reduct

EC number: =2.7.7.4

Molecular weight: Translated: 34619; Mature: 34488

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANLTHLQRLEAESIHIMRGVAANFSKPVMLYSIGKDSSVLLHLAMKAFYPAKPPFPFL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEE
HVDTTWKFREMIEFRDRMAAELGFDLLVHINEEGVRDGINPFDHGSNVHTHIMKTVALRQ
EECCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHH
ALDKYGFDAAFGGARRDEEKSRAKERVFSFRTASHTWDPKNQRPEMWKIYNTRVAQGESI
HHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEECCCCCE
RVFPLSNWTELDIWQYILQEGIPIVPLYFAKKRPVVNRGGMTIMVDDDRMKLLPGETVEE
EEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEECCCCHHHH
RMVRFRTLGCYPLTGAIDSCAATLEDIVSEMLTARTSERQGRLIDRDEAGSMEKKKREGY
HHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCC
F
C
>Mature Secondary Structure 
TANLTHLQRLEAESIHIMRGVAANFSKPVMLYSIGKDSSVLLHLAMKAFYPAKPPFPFL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEE
HVDTTWKFREMIEFRDRMAAELGFDLLVHINEEGVRDGINPFDHGSNVHTHIMKTVALRQ
EECCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHH
ALDKYGFDAAFGGARRDEEKSRAKERVFSFRTASHTWDPKNQRPEMWKIYNTRVAQGESI
HHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEECCCCCE
RVFPLSNWTELDIWQYILQEGIPIVPLYFAKKRPVVNRGGMTIMVDDDRMKLLPGETVEE
EEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEECCCCHHHH
RMVRFRTLGCYPLTGAIDSCAATLEDIVSEMLTARTSERQGRLIDRDEAGSMEKKKREGY
HHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA