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The map label for this gene is accD

Identifier: 110633020

GI number: 110633020

Start: 742143

End: 743066

Strand: Reverse

Name: accD

Synonym: Meso_0663

Alternate gene names: 110633020

Gene position: 743066-742143 (Counterclockwise)

Preceding gene: 110633021

Following gene: 110633019

Centisome position: 16.84

GC content: 62.55

Gene sequence:

>924_bases
ATGAACTGGATTACCAACTACGTCCGGCCGAAGATCAACTCCATGCTCGGCCGCCGAGAGATGCCGGAAAATCTCTGGAT
CAAGGACCCGGAGTCGGGCGAGATGGTCTTTCACAAGGACTTGGAGGAGAACCAGTGGGTGGTCCCCGCCTCGGGCTATC
ACATAAAGATCTCCGCCAAGGATCGGCTGAAGCATTTCTTCGACAACGGCGCCTATGAGACGCTGGAAAATCCGAAGGCT
GGCGTCGATCCGCTGAAGTTTCGCGATGAGCGGCGCTATATCGACCGGCTGCGCGATGCGAAGGCCAAGACGAACCTGGA
CGACGCCGTGGTGAACGCGATCGGCCGGATCGAAGGCCTGGAGATCCTCGCAACGGTGCAGGACTTTGCGTTCATGGGCG
GATCGCTCGGCATGGCGGCCGGCGAGGCGATCGTTCGCGGCTTCGAGACGGCAGTGGAACGCCGCCTGCCGCTCGTCCTC
TTCGCGGCCTCGGGCGGCGCACGCATGCAGGAGGGAATCCTCTCGCTGATGCAGCTTCCACGCACCACAGTGGCGGTGGA
CAGGCTCAAGGAGGCGGGCCTGCCTTACATCGTGGTGCTCACCAATCCGACGACCGGCGGCGTCACCGCCTCTTACGCGA
TGCTGGGTGACGTGCATATCGCGGAACCCGGAGCACTTATCGGCTTTGCCGGGCCGCGTGTGATCGAGCAGACCATCCGC
GAGAAATTGCCGGAAGGCTTCCAGCGCGCCGAATATCTGAAGGAACACGGGATGGTGGACATGGTCGTCTCCCGGCTTGA
GATGAAGGCGACCATAGCGCGCCTCCTGAAAATCTTGCTCAAGGAACAGGCGACCGAGGAAAACGGGAGCCGGCGACTGC
CTGCGCCGGAGGCCGCCGTTGTGGAAGCCGCGGTGAACGCCTGA

Upstream 100 bases:

>100_bases
GCGGCCTTGCCGATGGCGTGCGCGAGGCGCGCATCACGGCCGCCGCCGAATAACGGACAATTTCTCCCGGAATTATATCG
GAGAGGAAGGAGCATCTGCC

Downstream 100 bases:

>100_bases
TCCCCCCGCGCAAGGTTTCGAGATCCTCTATGAGTGCCGCCGAGCGCGCCATTGACCGCCTGATGGCGCTCCACCCGAAG
GGGTTCGACCTCTCGTTGGA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNWITNYVRPKINSMLGRREMPENLWIKDPESGEMVFHKDLEENQWVVPASGYHIKISAKDRLKHFFDNGAYETLENPKA
GVDPLKFRDERRYIDRLRDAKAKTNLDDAVVNAIGRIEGLEILATVQDFAFMGGSLGMAAGEAIVRGFETAVERRLPLVL
FAASGGARMQEGILSLMQLPRTTVAVDRLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHIAEPGALIGFAGPRVIEQTIR
EKLPEGFQRAEYLKEHGMVDMVVSRLEMKATIARLLKILLKEQATEENGSRRLPAPEAAVVEAAVNA

Sequences:

>Translated_307_residues
MNWITNYVRPKINSMLGRREMPENLWIKDPESGEMVFHKDLEENQWVVPASGYHIKISAKDRLKHFFDNGAYETLENPKA
GVDPLKFRDERRYIDRLRDAKAKTNLDDAVVNAIGRIEGLEILATVQDFAFMGGSLGMAAGEAIVRGFETAVERRLPLVL
FAASGGARMQEGILSLMQLPRTTVAVDRLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHIAEPGALIGFAGPRVIEQTIR
EKLPEGFQRAEYLKEHGMVDMVVSRLEMKATIARLLKILLKEQATEENGSRRLPAPEAAVVEAAVNA
>Mature_307_residues
MNWITNYVRPKINSMLGRREMPENLWIKDPESGEMVFHKDLEENQWVVPASGYHIKISAKDRLKHFFDNGAYETLENPKA
GVDPLKFRDERRYIDRLRDAKAKTNLDDAVVNAIGRIEGLEILATVQDFAFMGGSLGMAAGEAIVRGFETAVERRLPLVL
FAASGGARMQEGILSLMQLPRTTVAVDRLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHIAEPGALIGFAGPRVIEQTIR
EKLPEGFQRAEYLKEHGMVDMVVSRLEMKATIARLLKILLKEQATEENGSRRLPAPEAAVVEAAVNA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=292, Percent_Identity=46.9178082191781, Blast_Score=271, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_MESSB (Q11KL2)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673228.1
- ProteinModelPortal:   Q11KL2
- SMR:   Q11KL2
- STRING:   Q11KL2
- GeneID:   4180687
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0663
- NMPDR:   fig|266779.1.peg.2799
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- PhylomeDB:   Q11KL2
- ProtClustDB:   PRK05654
- BioCyc:   MSP266779:MESO_0663-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 33984; Mature: 33984

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50980 COA_CT_NTER; PS01159 WW_DOMAIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWITNYVRPKINSMLGRREMPENLWIKDPESGEMVFHKDLEENQWVVPASGYHIKISAK
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCEEEEEEHH
DRLKHFFDNGAYETLENPKAGVDPLKFRDERRYIDRLRDAKAKTNLDDAVVNAIGRIEGL
HHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHH
EILATVQDFAFMGGSLGMAAGEAIVRGFETAVERRLPLVLFAASGGARMQEGILSLMQLP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
RTTVAVDRLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHIAEPGALIGFAGPRVIEQTIR
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCEEECCCCCEEECCCHHHHHHHHH
EKLPEGFQRAEYLKEHGMVDMVVSRLEMKATIARLLKILLKEQATEENGSRRLPAPEAAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
VEAAVNA
HHHHHCC
>Mature Secondary Structure
MNWITNYVRPKINSMLGRREMPENLWIKDPESGEMVFHKDLEENQWVVPASGYHIKISAK
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCEEEEEEHH
DRLKHFFDNGAYETLENPKAGVDPLKFRDERRYIDRLRDAKAKTNLDDAVVNAIGRIEGL
HHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHH
EILATVQDFAFMGGSLGMAAGEAIVRGFETAVERRLPLVLFAASGGARMQEGILSLMQLP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
RTTVAVDRLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHIAEPGALIGFAGPRVIEQTIR
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCEEECCCCCEEECCCHHHHHHHHH
EKLPEGFQRAEYLKEHGMVDMVVSRLEMKATIARLLKILLKEQATEENGSRRLPAPEAAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
VEAAVNA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA