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The map label for this gene is appB [H]

Identifier: 110632921

GI number: 110632921

Start: 620664

End: 621632

Strand: Reverse

Name: appB [H]

Synonym: Meso_0562

Alternate gene names: 110632921

Gene position: 621632-620664 (Counterclockwise)

Preceding gene: 110632922

Following gene: 110632920

Centisome position: 14.09

GC content: 55.31

Gene sequence:

>969_bases
ATGCAGTTTCTCGGTTACGTCTCCTGGCGCCTGCTGAAGGCTGCCGCTTTGCTGGTGGCCGTGATATCCTTGAATTTCCT
GTTGATCAGGATGGTTCCTGGAGATCCCGCGACCGTTATTGCCGGTGAAAGCGGCATGGCCGACGCGGATTTCGTAGCAC
GAATCCGTGAAATATATGGGTTGGACCAGCCTTTGCTGGTCCAACTGAAAACCTACCTCGTGAATACGCTTTCTCTGGAT
TTCGGCCATTCGTATCGCCTCCAGACGGATGTACTTGCGCTGATCATCGAACGGCTTCCGGCAACGATCGCCCTAACTGG
CGCCGCATTCATATTCTCATTGGTGGTGGGGGTGAGTCTTGGCGTGATCGCGGGTTCGCGCCCAGGCAGCAAAGTGGACG
TCGCCATCCAGTTCGTATCCGTCGCGCTTTATTCCGTTCCTGTGTTCTGGATCGGCTTGATGTTGATACTCGTGTTCTCG
CTGAAGCTACATTGGCTTCCAGCATCAGGTACGGGATTTGAATACGGACAAATCCCCGGTGTGCTGGAATTTCTGAGTCA
CCTGCTGTTGCCGATGATCACGCTGTCGCTGTTCTACATCGCCGTCTACATTCGGCTTGCGCGCACCTCAGTCGTCGACG
TAACGCATCAGGATTTTGTCAGGACCGCGAAGTCGAAGGGCCTCCCTTCGGCGTTCATTCTGCGCAAGCACGTGCTCCCG
AACGCCATATTGCCGGTAGTCACCATGGCTGCGCTTCAGGCGGGGCACCTCGTCAGTGGATCGATAGCCGTCGAAACGAT
CTTCGCTTGGCCAGGCATCGGGAGACTTGGCTACGAGGCACTCGTTCAGCGCGACTATAACATGCTGTTGGGTGTGTTCC
TGGTCACGGCAACCATGGTCGTTCTGCTGAATCTCGTCGCTGACGTTCTGTATGTTGTCGTTGATCCAAGAATAGAGCTG
GTGCGATGA

Upstream 100 bases:

>100_bases
GCGCTTCACCGTCAGCCAAAAGAATGTTCACAACCTGGTGACGGACGCGTTCGGACCATGGGGTTCATGGGCAAGCGCCT
ACATTGAATAGTGATCAGCT

Downstream 100 bases:

>100_bases
GGTATTTTTATTCGGTTCCCAGGAGTGTGCTTACCTTTTGCGGTTTTAATTGGCAGATCGCAAATGGCGCGGGCATCATC
GCCCTATTGGCGCTGGTTGC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MQFLGYVSWRLLKAAALLVAVISLNFLLIRMVPGDPATVIAGESGMADADFVARIREIYGLDQPLLVQLKTYLVNTLSLD
FGHSYRLQTDVLALIIERLPATIALTGAAFIFSLVVGVSLGVIAGSRPGSKVDVAIQFVSVALYSVPVFWIGLMLILVFS
LKLHWLPASGTGFEYGQIPGVLEFLSHLLLPMITLSLFYIAVYIRLARTSVVDVTHQDFVRTAKSKGLPSAFILRKHVLP
NAILPVVTMAALQAGHLVSGSIAVETIFAWPGIGRLGYEALVQRDYNMLLGVFLVTATMVVLLNLVADVLYVVVDPRIEL
VR

Sequences:

>Translated_322_residues
MQFLGYVSWRLLKAAALLVAVISLNFLLIRMVPGDPATVIAGESGMADADFVARIREIYGLDQPLLVQLKTYLVNTLSLD
FGHSYRLQTDVLALIIERLPATIALTGAAFIFSLVVGVSLGVIAGSRPGSKVDVAIQFVSVALYSVPVFWIGLMLILVFS
LKLHWLPASGTGFEYGQIPGVLEFLSHLLLPMITLSLFYIAVYIRLARTSVVDVTHQDFVRTAKSKGLPSAFILRKHVLP
NAILPVVTMAALQAGHLVSGSIAVETIFAWPGIGRLGYEALVQRDYNMLLGVFLVTATMVVLLNLVADVLYVVVDPRIEL
VR
>Mature_322_residues
MQFLGYVSWRLLKAAALLVAVISLNFLLIRMVPGDPATVIAGESGMADADFVARIREIYGLDQPLLVQLKTYLVNTLSLD
FGHSYRLQTDVLALIIERLPATIALTGAAFIFSLVVGVSLGVIAGSRPGSKVDVAIQFVSVALYSVPVFWIGLMLILVFS
LKLHWLPASGTGFEYGQIPGVLEFLSHLLLPMITLSLFYIAVYIRLARTSVVDVTHQDFVRTAKSKGLPSAFILRKHVLP
NAILPVVTMAALQAGHLVSGSIAVETIFAWPGIGRLGYEALVQRDYNMLLGVFLVTATMVVLLNLVADVLYVVVDPRIEL
VR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=321, Percent_Identity=36.4485981308411, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787053, Length=316, Percent_Identity=38.6075949367089, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1789888, Length=317, Percent_Identity=35.9621451104101, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1787497, Length=317, Percent_Identity=34.0694006309148, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787761, Length=336, Percent_Identity=31.8452380952381, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787550, Length=257, Percent_Identity=33.852140077821, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788504, Length=358, Percent_Identity=28.4916201117318, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35060; Mature: 35060

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFLGYVSWRLLKAAALLVAVISLNFLLIRMVPGDPATVIAGESGMADADFVARIREIYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHC
LDQPLLVQLKTYLVNTLSLDFGHSYRLQTDVLALIIERLPATIALTGAAFIFSLVVGVSL
CCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVIAGSRPGSKVDVAIQFVSVALYSVPVFWIGLMLILVFSLKLHWLPASGTGFEYGQIPG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCH
VLEFLSHLLLPMITLSLFYIAVYIRLARTSVVDVTHQDFVRTAKSKGLPSAFILRKHVLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
NAILPVVTMAALQAGHLVSGSIAVETIFAWPGIGRLGYEALVQRDYNMLLGVFLVTATMV
HHHHHHHHHHHHHHCCCEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLNLVADVLYVVVDPRIELVR
HHHHHHHHHHHHHCCCCHHHCC
>Mature Secondary Structure
MQFLGYVSWRLLKAAALLVAVISLNFLLIRMVPGDPATVIAGESGMADADFVARIREIYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHC
LDQPLLVQLKTYLVNTLSLDFGHSYRLQTDVLALIIERLPATIALTGAAFIFSLVVGVSL
CCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVIAGSRPGSKVDVAIQFVSVALYSVPVFWIGLMLILVFSLKLHWLPASGTGFEYGQIPG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCH
VLEFLSHLLLPMITLSLFYIAVYIRLARTSVVDVTHQDFVRTAKSKGLPSAFILRKHVLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
NAILPVVTMAALQAGHLVSGSIAVETIFAWPGIGRLGYEALVQRDYNMLLGVFLVTATMV
HHHHHHHHHHHHHHCCCEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLNLVADVLYVVVDPRIELVR
HHHHHHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]