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The map label for this gene is appC [H]

Identifier: 110632920

GI number: 110632920

Start: 619813

End: 620667

Strand: Reverse

Name: appC [H]

Synonym: Meso_0561

Alternate gene names: 110632920

Gene position: 620667-619813 (Counterclockwise)

Preceding gene: 110632921

Following gene: 110632919

Centisome position: 14.07

GC content: 55.56

Gene sequence:

>855_bases
ATGAGGTATTTTTATTCGGTTCCCAGGAGTGTGCTTACCTTTTGCGGTTTTAATTGGCAGATCGCAAATGGCGCGGGCAT
CATCGCCCTATTGGCGCTGGTTGCATTTGGCGCATCACCAATCTCGCCTTACGGGGCGTGGGAGATTGCGGGCACTCCAT
GTCTTCCACCGCTTTCGCCGGAACATCTGCTCGGCACCGATATGCTGGGTCGCGACGTCCTTTCCGGCGTGATCTACGGT
GCTCAATCGTCGTTGCTGGTCGGACTCGCTTCAGCAGGCGCGGCAATTGTCTTGGGAATCGTTGTAGGCGCATTTGCCGG
CTACTATGGCGGAATCGTCGACGATATTTTGATGAGGTTCACCGAGTTCCTGCAAACTATGCCAGGCTTGGCACTCGCGC
TTGTTTTGGTCGCCGTTCTTGGGCCATCGATCTGGTCCGTCGTGATCGCCATCACAATTGTGAGCTGGGCACCGGTCGCC
CGTTTGATCCGTGCTGAATTCTTATCGCTGCGCGGTCGGGAATTCGTTCTGGCTGCAATCGTGCTCGGTCAGCGAAACAC
AAAAATCATTCTTTCCCAAATGCTACCGAATGCGCTCGGGCCAATTGTGTCTACGGCATCCCTGAAGGTGTCGAGCGCCA
TACTGACAGAGTCGACGATAAGCTTTCTCGGGCTCGGCGACACGACTAGAATGTCGTGGGGCATGATGATCGGTAACGCG
CAGGGGCAACTCCGGGAAGCATGGTGGATGAGCGTTTTTCCGGGGGTTGCGCTGTTTGTGACCATACTCGGACTTACGCT
TCTCTCTGACGGAATTGCGCGCTCAGGTAGTGCACGCAAGCAAAGCATGCTGTGA

Upstream 100 bases:

>100_bases
TGTTGGGTGTGTTCCTGGTCACGGCAACCATGGTCGTTCTGCTGAATCTCGTCGCTGACGTTCTGTATGTTGTCGTTGAT
CCAAGAATAGAGCTGGTGCG

Downstream 100 bases:

>100_bases
GGACAAAGTGCTCGAGATAGAAAAGCTTAGCATCGTTCTTCCTTCCGGCGCCGACAGGGCTCTCGCGATTAAGGACGTTT
CGTTCAGCGTGAAGTCCGGT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MRYFYSVPRSVLTFCGFNWQIANGAGIIALLALVAFGASPISPYGAWEIAGTPCLPPLSPEHLLGTDMLGRDVLSGVIYG
AQSSLLVGLASAGAAIVLGIVVGAFAGYYGGIVDDILMRFTEFLQTMPGLALALVLVAVLGPSIWSVVIAITIVSWAPVA
RLIRAEFLSLRGREFVLAAIVLGQRNTKIILSQMLPNALGPIVSTASLKVSSAILTESTISFLGLGDTTRMSWGMMIGNA
QGQLREAWWMSVFPGVALFVTILGLTLLSDGIARSGSARKQSML

Sequences:

>Translated_284_residues
MRYFYSVPRSVLTFCGFNWQIANGAGIIALLALVAFGASPISPYGAWEIAGTPCLPPLSPEHLLGTDMLGRDVLSGVIYG
AQSSLLVGLASAGAAIVLGIVVGAFAGYYGGIVDDILMRFTEFLQTMPGLALALVLVAVLGPSIWSVVIAITIVSWAPVA
RLIRAEFLSLRGREFVLAAIVLGQRNTKIILSQMLPNALGPIVSTASLKVSSAILTESTISFLGLGDTTRMSWGMMIGNA
QGQLREAWWMSVFPGVALFVTILGLTLLSDGIARSGSARKQSML
>Mature_284_residues
MRYFYSVPRSVLTFCGFNWQIANGAGIIALLALVAFGASPISPYGAWEIAGTPCLPPLSPEHLLGTDMLGRDVLSGVIYG
AQSSLLVGLASAGAAIVLGIVVGAFAGYYGGIVDDILMRFTEFLQTMPGLALALVLVAVLGPSIWSVVIAITIVSWAPVA
RLIRAEFLSLRGREFVLAAIVLGQRNTKIILSQMLPNALGPIVSTASLKVSSAILTESTISFLGLGDTTRMSWGMMIGNA
QGQLREAWWMSVFPGVALFVTILGLTLLSDGIARSGSARKQSML

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=219, Percent_Identity=38.3561643835616, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787054, Length=249, Percent_Identity=36.144578313253, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789964, Length=247, Percent_Identity=39.6761133603239, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787498, Length=249, Percent_Identity=36.9477911646586, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789889, Length=218, Percent_Identity=34.8623853211009, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788505, Length=236, Percent_Identity=33.4745762711864, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787549, Length=257, Percent_Identity=31.5175097276265, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29934; Mature: 29934

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYFYSVPRSVLTFCGFNWQIANGAGIIALLALVAFGASPISPYGAWEIAGTPCLPPLSP
CCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCH
EHLLGTDMLGRDVLSGVIYGAQSSLLVGLASAGAAIVLGIVVGAFAGYYGGIVDDILMRF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEFLQTMPGLALALVLVAVLGPSIWSVVIAITIVSWAPVARLIRAEFLSLRGREFVLAAI
HHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VLGQRNTKIILSQMLPNALGPIVSTASLKVSSAILTESTISFLGLGDTTRMSWGMMIGNA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEECC
QGQLREAWWMSVFPGVALFVTILGLTLLSDGIARSGSARKQSML
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure
MRYFYSVPRSVLTFCGFNWQIANGAGIIALLALVAFGASPISPYGAWEIAGTPCLPPLSP
CCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCH
EHLLGTDMLGRDVLSGVIYGAQSSLLVGLASAGAAIVLGIVVGAFAGYYGGIVDDILMRF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEFLQTMPGLALALVLVAVLGPSIWSVVIAITIVSWAPVARLIRAEFLSLRGREFVLAAI
HHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VLGQRNTKIILSQMLPNALGPIVSTASLKVSSAILTESTISFLGLGDTTRMSWGMMIGNA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEECC
QGQLREAWWMSVFPGVALFVTILGLTLLSDGIARSGSARKQSML
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]