Click here to switch to the map view.

The map label for this gene is dppC [H]

Identifier: 110632427

GI number: 110632427

Start: 88460

End: 89395

Strand: Reverse

Name: dppC [H]

Synonym: Meso_0065

Alternate gene names: 110632427

Gene position: 89395-88460 (Counterclockwise)

Preceding gene: 110632428

Following gene: 110632426

Centisome position: 2.03

GC content: 63.68

Gene sequence:

>936_bases
ATGGCTACGACGAATCTCAAAGAAGCCGATGCAGCCATCGGGCTCGAAGGCGGACCAGTGGTGGACGCGAGCCGCCGCGC
CATGCTGGCCGAGTTCTGGTACTATTTCCGCCAGAACCGCGGCGCTGTACTGGGCTTGTGGGTTTTCCTGCTGATCGTCG
CGGTGGCGATCCTGGCTCCGGTAATCGCGCCTCATAATCCAACCGCGCAGGTGCGCGGCGCCTTCCTGGTGCCGCCCGCG
TGGGAAGAGGGTGGAAGCTGGGACTACATCCTTGGCACGGATGCCGTGGGCCGCGACATCCTCTCACGCCTGATCTACGG
CGCACGCTTCTCGCTTTTCATCGGTGTGGTGGTGGTCACGCTGGCGGTGGTGGTCGGCGTCGTGGTGGGCGTAATCGCCG
GCTATTTCCGCGGGGCCGTGGACACTGTGATCATGCGGCTCATGGATATCATCCTGGCCTTCCCGTCGCTGTTGCTGGCC
CTGGTGCTGGTGGCAGTCCTGGGACCGGGGTTGATGAACGCCATGATCGCTATCGCACTGGTGCTGCAACCGCATTTCGT
GCGGCTTACGCGCGCCGCCGTGATGGCGGAAAAGAACAGGGATTATGTGACCGCCGCGAAGGTGGCGGGCGCGGGCAATA
TCCGGCTGATGTTCAAGACCATCCTGCCGAACTGCACGGCGCCGTTAATCGTGCAGGCGACGCTCTCGTTCTCCAACGCC
ATCCTCGATGCCGCCGCGCTCGGCTTTCTGGGCATGGGCGCGCAGCCGCCTACGCCCGAATGGGGTACGATGCTGGCGGA
AGCGCGCGAATTCATCCTGCGCGCCTGGTGGGTAGTGACCTTCCCCGGCCTTGCCATTCTCATCACGGTTTTGGCCATCA
ATCTTATGGGCGACGGCCTGCGCGACGCCCTCGATCCGAAACTGAAGAGGTCGTGA

Upstream 100 bases:

>100_bases
TGGTGCAGGGCGGGCTGCTGCTCATCGCCGGCATCATCATGGTCGTGAACCTGATCGTGGATGTGCTCTACGGTCTCATC
AACCCGAGGATCAGGCACTG

Downstream 100 bases:

>100_bases
GCATGGCTCTGCTCGAGATCGAGAACCTTTCCGTCGAGTTCGAAACCGCAACCGGCAAGCTGCGGGCGGTGGACGGCATC
TCGCTTTCCGTGGATGAGGG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MATTNLKEADAAIGLEGGPVVDASRRAMLAEFWYYFRQNRGAVLGLWVFLLIVAVAILAPVIAPHNPTAQVRGAFLVPPA
WEEGGSWDYILGTDAVGRDILSRLIYGARFSLFIGVVVVTLAVVVGVVVGVIAGYFRGAVDTVIMRLMDIILAFPSLLLA
LVLVAVLGPGLMNAMIAIALVLQPHFVRLTRAAVMAEKNRDYVTAAKVAGAGNIRLMFKTILPNCTAPLIVQATLSFSNA
ILDAAALGFLGMGAQPPTPEWGTMLAEAREFILRAWWVVTFPGLAILITVLAINLMGDGLRDALDPKLKRS

Sequences:

>Translated_311_residues
MATTNLKEADAAIGLEGGPVVDASRRAMLAEFWYYFRQNRGAVLGLWVFLLIVAVAILAPVIAPHNPTAQVRGAFLVPPA
WEEGGSWDYILGTDAVGRDILSRLIYGARFSLFIGVVVVTLAVVVGVVVGVIAGYFRGAVDTVIMRLMDIILAFPSLLLA
LVLVAVLGPGLMNAMIAIALVLQPHFVRLTRAAVMAEKNRDYVTAAKVAGAGNIRLMFKTILPNCTAPLIVQATLSFSNA
ILDAAALGFLGMGAQPPTPEWGTMLAEAREFILRAWWVVTFPGLAILITVLAINLMGDGLRDALDPKLKRS
>Mature_310_residues
ATTNLKEADAAIGLEGGPVVDASRRAMLAEFWYYFRQNRGAVLGLWVFLLIVAVAILAPVIAPHNPTAQVRGAFLVPPAW
EEGGSWDYILGTDAVGRDILSRLIYGARFSLFIGVVVVTLAVVVGVVVGVIAGYFRGAVDTVIMRLMDIILAFPSLLLAL
VLVAVLGPGLMNAMIAIALVLQPHFVRLTRAAVMAEKNRDYVTAAKVAGAGNIRLMFKTILPNCTAPLIVQATLSFSNAI
LDAAALGFLGMGAQPPTPEWGTMLAEAREFILRAWWVVTFPGLAILITVLAINLMGDGLRDALDPKLKRS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=282, Percent_Identity=67.0212765957447, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1787760, Length=260, Percent_Identity=46.1538461538462, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1787054, Length=296, Percent_Identity=41.8918918918919, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1787549, Length=272, Percent_Identity=42.2794117647059, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=38.7755102040816, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1787498, Length=306, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=29.8165137614679, Blast_Score=107, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33262; Mature: 33131

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTNLKEADAAIGLEGGPVVDASRRAMLAEFWYYFRQNRGAVLGLWVFLLIVAVAILAP
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VIAPHNPTAQVRGAFLVPPAWEEGGSWDYILGTDAVGRDILSRLIYGARFSLFIGVVVVT
HHCCCCCCHHHCCCEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVVVGVVVGVIAGYFRGAVDTVIMRLMDIILAFPSLLLALVLVAVLGPGLMNAMIAIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VLQPHFVRLTRAAVMAEKNRDYVTAAKVAGAGNIRLMFKTILPNCTAPLIVQATLSFSNA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEHHHHHCCCCCCCHHHHHHHHHHHH
ILDAAALGFLGMGAQPPTPEWGTMLAEAREFILRAWWVVTFPGLAILITVLAINLMGDGL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RDALDPKLKRS
HHHCCCCCCCC
>Mature Secondary Structure 
ATTNLKEADAAIGLEGGPVVDASRRAMLAEFWYYFRQNRGAVLGLWVFLLIVAVAILAP
CCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH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HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]