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The map label for this gene is dppB [H]

Identifier: 110632428

GI number: 110632428

Start: 89395

End: 90399

Strand: Reverse

Name: dppB [H]

Synonym: Meso_0066

Alternate gene names: 110632428

Gene position: 90399-89395 (Counterclockwise)

Preceding gene: 110632429

Following gene: 110632427

Centisome position: 2.05

GC content: 61.99

Gene sequence:

>1005_bases
ATGTTCCGGTTTCTGATCCGGCGGCTCGCGGTCCTCATCCCGACTTTCCTCGGCGTGTCCATAATCGCCTTCGCTTTCAT
TCGTGTCCTGCCGGGCGATCCGGTGATGCTGATGTCCGGCGAGCGCGTGATGTCCCCGGAGCGCCATGCCGCGCTCACCC
GCGAACTCGGCTTCGACCGGCCGATCTGGATTCAATATCTCGATTACATCGGCGGTGTCGTCCAAGGCGATTTTGGCAGT
TCCATCGTCACCAAGCGGCCGGTGATGGATGATTTTCTCGCGCTCTTCCCTGCCACGCTCGAGCTTTCGATCTGCGCCAT
CATCCTCGCAGTCGCCATCGGCGTGCCGTTCGGGGTGTTGGCGGCGGTAAAGCGCGGCTCTTGGCTCGATCAGTCGGTTA
TGGGCTTTGCGCTCGTCGGCTATTCCATGCCGATCTTTTGGTGGGGCCTGCTGCTCATCATCCTCTTCTCCGGCGTGCTG
CAGTGGACTCCGGTATCAGGCCGCATCTCGCTCCTCTACTTCTTCCCGCCCGTAACCGGCTTCATGCTTATCGACAGCCT
GCTTTCGGGACAGGCGGGAGCCTTCAAGTCCGCCCTCTCGCATTTGATCCTGCCGACGGTCGTGCTTGCCACGATCCCGC
TTGCCGTCATCGCGCGGCAGACGCGCTCGGCGATGCTGGAGGTGCTGGGCGAGGACTATGTGCGCACGGCGCGCGCAAAG
GGCCTGCCGCCAAGGCGGGTGATCGGACTGCATGCGCTGCGCAATGCGCTGATACCAGTCGTCACCACGATTGGCCTGCA
GGTGGGCGTGTTGATGGCGGGCGCTATACTTACCGAAACGATTTTCTCCTGGCCGGGCATCGGCAAGTGGATGGTCGATA
GCGTCTTCCGGCGCGATTACGCAGTGGTGCAGGGCGGGCTGCTGCTCATCGCCGGCATCATCATGGTCGTGAACCTGATC
GTGGATGTGCTCTACGGTCTCATCAACCCGAGGATCAGGCACTGA

Upstream 100 bases:

>100_bases
AATGTGAGGCGCGTCGGGAAACCGGCGCGCTTCTTTTCGATTATGACTGAGAAGCAGCCCTTTTCGGGCCTATGGTTCTG
ACCAGGAGATTTGAAGCATT

Downstream 100 bases:

>100_bases
TGGCTACGACGAATCTCAAAGAAGCCGATGCAGCCATCGGGCTCGAAGGCGGACCAGTGGTGGACGCGAGCCGCCGCGCC
ATGCTGGCCGAGTTCTGGTA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MFRFLIRRLAVLIPTFLGVSIIAFAFIRVLPGDPVMLMSGERVMSPERHAALTRELGFDRPIWIQYLDYIGGVVQGDFGS
SIVTKRPVMDDFLALFPATLELSICAIILAVAIGVPFGVLAAVKRGSWLDQSVMGFALVGYSMPIFWWGLLLIILFSGVL
QWTPVSGRISLLYFFPPVTGFMLIDSLLSGQAGAFKSALSHLILPTVVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
GLPPRRVIGLHALRNALIPVVTTIGLQVGVLMAGAILTETIFSWPGIGKWMVDSVFRRDYAVVQGGLLLIAGIIMVVNLI
VDVLYGLINPRIRH

Sequences:

>Translated_334_residues
MFRFLIRRLAVLIPTFLGVSIIAFAFIRVLPGDPVMLMSGERVMSPERHAALTRELGFDRPIWIQYLDYIGGVVQGDFGS
SIVTKRPVMDDFLALFPATLELSICAIILAVAIGVPFGVLAAVKRGSWLDQSVMGFALVGYSMPIFWWGLLLIILFSGVL
QWTPVSGRISLLYFFPPVTGFMLIDSLLSGQAGAFKSALSHLILPTVVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
GLPPRRVIGLHALRNALIPVVTTIGLQVGVLMAGAILTETIFSWPGIGKWMVDSVFRRDYAVVQGGLLLIAGIIMVVNLI
VDVLYGLINPRIRH
>Mature_334_residues
MFRFLIRRLAVLIPTFLGVSIIAFAFIRVLPGDPVMLMSGERVMSPERHAALTRELGFDRPIWIQYLDYIGGVVQGDFGS
SIVTKRPVMDDFLALFPATLELSICAIILAVAIGVPFGVLAAVKRGSWLDQSVMGFALVGYSMPIFWWGLLLIILFSGVL
QWTPVSGRISLLYFFPPVTGFMLIDSLLSGQAGAFKSALSHLILPTVVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
GLPPRRVIGLHALRNALIPVVTTIGLQVGVLMAGAILTETIFSWPGIGKWMVDSVFRRDYAVVQGGLLLIAGIIMVVNLI
VDVLYGLINPRIRH

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=62.0178041543027, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=42.0118343195266, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1787761, Length=330, Percent_Identity=46.0606060606061, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=37.0149253731343, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787550, Length=276, Percent_Identity=36.9565217391304, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1787497, Length=335, Percent_Identity=37.0149253731343, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1788504, Length=372, Percent_Identity=26.6129032258064, Blast_Score=132, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36512; Mature: 36512

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRFLIRRLAVLIPTFLGVSIIAFAFIRVLPGDPVMLMSGERVMSPERHAALTRELGFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCHHHHHHHHHHCCCC
PIWIQYLDYIGGVVQGDFGSSIVTKRPVMDDFLALFPATLELSICAIILAVAIGVPFGVL
HHHHHHHHHHCCHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
AAVKRGSWLDQSVMGFALVGYSMPIFWWGLLLIILFSGVLQWTPVSGRISLLYFFPPVTG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHH
FMLIDSLLSGQAGAFKSALSHLILPTVVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLPPRRVIGLHALRNALIPVVTTIGLQVGVLMAGAILTETIFSWPGIGKWMVDSVFRRDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVVQGGLLLIAGIIMVVNLIVDVLYGLINPRIRH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFRFLIRRLAVLIPTFLGVSIIAFAFIRVLPGDPVMLMSGERVMSPERHAALTRELGFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCHHHHHHHHHHCCCC
PIWIQYLDYIGGVVQGDFGSSIVTKRPVMDDFLALFPATLELSICAIILAVAIGVPFGVL
HHHHHHHHHHCCHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
AAVKRGSWLDQSVMGFALVGYSMPIFWWGLLLIILFSGVLQWTPVSGRISLLYFFPPVTG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHH
FMLIDSLLSGQAGAFKSALSHLILPTVVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLPPRRVIGLHALRNALIPVVTTIGLQVGVLMAGAILTETIFSWPGIGKWMVDSVFRRDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVVQGGLLLIAGIIMVVNLIVDVLYGLINPRIRH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]