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The map label for this gene is rocF [H]

Identifier: 109948227

GI number: 109948227

Start: 1534413

End: 1535363

Strand: Reverse

Name: rocF [H]

Synonym: Hac_1761

Alternate gene names: 109948227

Gene position: 1535363-1534413 (Counterclockwise)

Preceding gene: 109948228

Following gene: 109948218

Centisome position: 98.81

GC content: 38.38

Gene sequence:

>951_bases
ATGATTTTAGTAGGATTAGAAGCCGAGTTAGGGGCGTCAAAAAAAGGCACAGATGCAGGCGTTAGGCGTTTGAGAGAGGC
TTTAAGCCTAAAATATAACGATTTAGTAAAAAACATGCAAATGATTATCCAAGAGCGTTGTGTACTTTATAAAGAGTTTA
GATACGCTAAAAATTTTGAAGATTACTATGTGTTTTGCAAAGAAAATTTGATCCCTTGCATGCAAGAAGTGTTTGCAAAA
AAAGATTTTCCTTTAATCTTAAGCTCAGAGCATGCGAACATGTTTGGGATTTTCCAAGCGTTTAGGAGCGTTCATAAAGA
CAAAAAAATAGGGATTTTGTATTTGGATGCGCATGCGGATATTCATACGGCTTATGACAGCGATTCAAAACACATCCATG
GCATGCCTTTAGGCATGGTTTTAAATCGTGTCCGTAGCGGGTTTAACCACATGAATGAAAGCGAAGAAAAAGCATGGCAA
AAGCTTTGCTCTTTGGGGCTAGAAAAGGGAGGGTTAGAAGTTGATCCTAAATGCTTGGTGTATTTTGGGGTAAGAAGCGT
TGAACAAAGTGAAAGAGATGTGATTAAAGAATTGCAAATCCCTTTATTTAGCGTGGATACGATAAGAGAAAACATGCAAG
AAGTGGTGAAAAAAACGAAAGAATTATTGCAAGAAGTGGGTATTATTTATCTTAGTTTGGATTTGGATATTATGGATGGC
AAGCTTTTCACCTCTACCGGCGTGCGCGAAAATCATGGGCTAAGTTTTAGCGAGTTAAAACAATTGCTAGGCATGCTTTT
AGAAAGTTTTAAGGATAGATTGAGAGCCGTTGAGGTCACCGAATACAACCCCACGGTAAGTACCAAGCACACCAATGAAG
AAGAGAAACAGGTTTTAGAAATACTAGATCTCATCATCAAGCACGCCAAAAACAACAGCGCCAACCATTAA

Upstream 100 bases:

>100_bases
TCTCACGCTAGTGTTTATGGGGCTTTGCTATGTGGCGTATTACGCGAGCAAAAACCAATGGGGCTATCAGCAAGAAAAAG
GACTTTAAAGGAGCGATAAA

Downstream 100 bases:

>100_bases
AAAGCGATTTTAATGCGTCTATCTTCATATTTGATTTCATTCTAATACAAGGATTTTTTCCAAATCTTGTTTGAAAGCTT
CTAGCACCTTTCTCCTGGCT

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MILVGLEAELGASKKGTDAGVRRLREALSLKYNDLVKNMQMIIQERCVLYKEFRYAKNFEDYYVFCKENLIPCMQEVFAK
KDFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNHMNESEEKAWQ
KLCSLGLEKGGLEVDPKCLVYFGVRSVEQSERDVIKELQIPLFSVDTIRENMQEVVKKTKELLQEVGIIYLSLDLDIMDG
KLFTSTGVRENHGLSFSELKQLLGMLLESFKDRLRAVEVTEYNPTVSTKHTNEEEKQVLEILDLIIKHAKNNSANH

Sequences:

>Translated_316_residues
MILVGLEAELGASKKGTDAGVRRLREALSLKYNDLVKNMQMIIQERCVLYKEFRYAKNFEDYYVFCKENLIPCMQEVFAK
KDFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNHMNESEEKAWQ
KLCSLGLEKGGLEVDPKCLVYFGVRSVEQSERDVIKELQIPLFSVDTIRENMQEVVKKTKELLQEVGIIYLSLDLDIMDG
KLFTSTGVRENHGLSFSELKQLLGMLLESFKDRLRAVEVTEYNPTVSTKHTNEEEKQVLEILDLIIKHAKNNSANH
>Mature_316_residues
MILVGLEAELGASKKGTDAGVRRLREALSLKYNDLVKNMQMIIQERCVLYKEFRYAKNFEDYYVFCKENLIPCMQEVFAK
KDFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNHMNESEEKAWQ
KLCSLGLEKGGLEVDPKCLVYFGVRSVEQSERDVIKELQIPLFSVDTIRENMQEVVKKTKELLQEVGIIYLSLDLDIMDG
KLFTSTGVRENHGLSFSELKQLLGMLLESFKDRLRAVEVTEYNPTVSTKHTNEEEKQVLEILDLIIKHAKNNSANH

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4502215, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325146, Length=219, Percent_Identity=29.6803652968037, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24638886, Length=307, Percent_Identity=24.7557003257329, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 36249; Mature: 36249

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVGLEAELGASKKGTDAGVRRLREALSLKYNDLVKNMQMIIQERCVLYKEFRYAKNFE
CEEEEECHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DYYVFCKENLIPCMQEVFAKKDFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHAD
HHEEEHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
IHTAYDSDSKHIHGMPLGMVLNRVRSGFNHMNESEEKAWQKLCSLGLEKGGLEVDPKCLV
EEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEE
YFGVRSVEQSERDVIKELQIPLFSVDTIRENMQEVVKKTKELLQEVGIIYLSLDLDIMDG
EECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECC
KLFTSTGVRENHGLSFSELKQLLGMLLESFKDRLRAVEVTEYNPTVSTKHTNEEEKQVLE
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHH
ILDLIIKHAKNNSANH
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MILVGLEAELGASKKGTDAGVRRLREALSLKYNDLVKNMQMIIQERCVLYKEFRYAKNFE
CEEEEECHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DYYVFCKENLIPCMQEVFAKKDFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHAD
HHEEEHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
IHTAYDSDSKHIHGMPLGMVLNRVRSGFNHMNESEEKAWQKLCSLGLEKGGLEVDPKCLV
EEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEE
YFGVRSVEQSERDVIKELQIPLFSVDTIRENMQEVVKKTKELLQEVGIIYLSLDLDIMDG
EECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECC
KLFTSTGVRENHGLSFSELKQLLGMLLESFKDRLRAVEVTEYNPTVSTKHTNEEEKQVLE
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHH
ILDLIIKHAKNNSANH
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]