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The map label for this gene is tlpB [H]

Identifier: 109947957

GI number: 109947957

Start: 1268043

End: 1269740

Strand: Reverse

Name: tlpB [H]

Synonym: Hac_1462

Alternate gene names: 109947957

Gene position: 1269740-1268043 (Counterclockwise)

Preceding gene: 109947958

Following gene: 109947956

Centisome position: 81.71

GC content: 40.28

Gene sequence:

>1698_bases
ATGATGTTTGCTTCAATATTTTCCTCATTTGGGGCGCGTATTGTGCTGGTCGTGTTAGCCACTCTTTTGGGTTTAGGAGG
GTTGTCCATTAGTTTGGTAAAGGTTATGCAAAAAGATGTGCTAGAGCAGATCATGGGGCATTTAGAAACCGAGCAATACA
GAAAGCGTGAAAAAACGCTCGCTTACATGACCAAAATTCTTGAACAAGGCATTCATGAGTATTACAAAAATTTTGATAAT
GCTACCGCAAGAAAAATGGCACTGGATTATTTTAAACGCATTAATGATGATAAGGGCATGATTTATATGGTGGTGGTGGA
TAAAAATGGGGTGGTATTGTTTGATCCTGTCAATCCCAAAACCATAGGCCAATCAGGGATTAGCTTGCAAAGCGTTGATG
GGGTGTATTATGTTAAGGGCTATTTGGAGGCGGCTAAAAAAGGGGGAGGCTACACTTATTATAAAATGTCCAAGTACGGT
GGGGGCGTGCCGGAGAAAAAATTCGCTTACTCACATTATGATGAAGTGTCTCAAATGGTGATCGCAGCGACTTCTTACTA
CACTGATATTGACGCCGAGAATAGGGCGATTAAAGAAGACATAGAGAAGGCTTTCAATGAAAGCACCGCAAAATTATTCC
TTTGGATATTGATAGCAACAATAGCGTTAGCGGTTTTAACGCTGATATATGCGAAATTAAAGATCGTGAAACGCATTGAT
GATCTAGTCCTTAAGATCAACGCTTTTAGCCATGGGGATAAGGATTTGAGAGCCAAAATTGATGTGGATGATCGCAACGA
TGAAATCTCGCAAGTGGGGCATGGAGTCAATTTGTTTGTAGAAAAAGCCCGTTTGATTATAGAAGAGACTAAGGGGATTT
CCACTCTCAATAAGACTTCAATGGACAAATTAGTCCAAATCACAAAAGAAACCCAAGAGAGCATGAAAAATTCCTCAACC
ACCTTAAATTCTGTGAAAGATAAAGCCACTGATGTGGCTAGCGTGATGAGCGCTTCTATAGAGCAGTCTCAAGGGTTAAG
GAAGCGTTTGATTGAAACGCAAGGGCTTGTGAAAGAGAGCAAGGATGCGATCGGAGATTTGTTTTATCAAATCATAGAGG
CCGCACACACTGAAGAAGAGCTGTCTAATAAAGTGGAACAATTGAGCCGCAACGCTGATGATGTCAAATCCATTTTGGAT
ATTATCAATGATATTGCTGATCAAACGAATTTATTAGCCCTAAACGCTGCTATTGAAGCCGCAAGAGCCGGTGAGCATGG
CAGAGGCTTTGCGGTGGTGGCTGATGAAGTTAGGAATTTAGCCGGACGCACTCAAAAGTCTTTAGCGGAAATCAACTCTA
CTATCATGGTGATTGTCCAAGAAATTAATGATGTGAGCTCGCAAATGAATCTCAATTCGCAAAAAATGGAGCGTTTGAGC
GATATGAGTAAAAGCGTGCAAGAAACTTATGAAAAAATGAGTGCTAATTTAAGTTCAGTCGTTTTAGACAGCAATCAAAG
CATGGACGATTACGCCAAATCCGGACGCCAAATTGAAGCGATGGTAAGTGATTTTATAAAGGTTGAAAAAGTGGCTTCTA
AAACTTTAGCTGACTATTCAGATATTTTAAAGATCGCTACGCATGTGAGTGAAACAACCAAGAATTTAGACAAACAAGTG
AATCTGTTTAAAACTTAG

Upstream 100 bases:

>100_bases
TTTAATTTAATTTTGGACCCCTCATTTTTCGGGGGGGGGGCATTTAGAAGCTAAACCCTAAAATTAGGGTTTGATTTAAA
AATGATATTATAGGAGATAA

Downstream 100 bases:

>100_bases
TTGGGGGGAGTTTATTATAAAAGGGTTTAATTGCTAAAAGTTTCAGTGATCACGGCGTGTTTTAATAGTGAAAAAACCAT
TGAAGACACCATTCTTTCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MMFASIFSSFGARIVLVVLATLLGLGGLSISLVKVMQKDVLEQIMGHLETEQYRKREKTLAYMTKILEQGIHEYYKNFDN
ATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPKTIGQSGISLQSVDGVYYVKGYLEAAKKGGGYTYYKMSKYG
GGVPEKKFAYSHYDEVSQMVIAATSYYTDIDAENRAIKEDIEKAFNESTAKLFLWILIATIALAVLTLIYAKLKIVKRID
DLVLKINAFSHGDKDLRAKIDVDDRNDEISQVGHGVNLFVEKARLIIEETKGISTLNKTSMDKLVQITKETQESMKNSST
TLNSVKDKATDVASVMSASIEQSQGLRKRLIETQGLVKESKDAIGDLFYQIIEAAHTEEELSNKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINDVSSQMNLNSQKMERLS
DMSKSVQETYEKMSANLSSVVLDSNQSMDDYAKSGRQIEAMVSDFIKVEKVASKTLADYSDILKIATHVSETTKNLDKQV
NLFKT

Sequences:

>Translated_565_residues
MMFASIFSSFGARIVLVVLATLLGLGGLSISLVKVMQKDVLEQIMGHLETEQYRKREKTLAYMTKILEQGIHEYYKNFDN
ATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPKTIGQSGISLQSVDGVYYVKGYLEAAKKGGGYTYYKMSKYG
GGVPEKKFAYSHYDEVSQMVIAATSYYTDIDAENRAIKEDIEKAFNESTAKLFLWILIATIALAVLTLIYAKLKIVKRID
DLVLKINAFSHGDKDLRAKIDVDDRNDEISQVGHGVNLFVEKARLIIEETKGISTLNKTSMDKLVQITKETQESMKNSST
TLNSVKDKATDVASVMSASIEQSQGLRKRLIETQGLVKESKDAIGDLFYQIIEAAHTEEELSNKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINDVSSQMNLNSQKMERLS
DMSKSVQETYEKMSANLSSVVLDSNQSMDDYAKSGRQIEAMVSDFIKVEKVASKTLADYSDILKIATHVSETTKNLDKQV
NLFKT
>Mature_565_residues
MMFASIFSSFGARIVLVVLATLLGLGGLSISLVKVMQKDVLEQIMGHLETEQYRKREKTLAYMTKILEQGIHEYYKNFDN
ATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPKTIGQSGISLQSVDGVYYVKGYLEAAKKGGGYTYYKMSKYG
GGVPEKKFAYSHYDEVSQMVIAATSYYTDIDAENRAIKEDIEKAFNESTAKLFLWILIATIALAVLTLIYAKLKIVKRID
DLVLKINAFSHGDKDLRAKIDVDDRNDEISQVGHGVNLFVEKARLIIEETKGISTLNKTSMDKLVQITKETQESMKNSST
TLNSVKDKATDVASVMSASIEQSQGLRKRLIETQGLVKESKDAIGDLFYQIIEAAHTEEELSNKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINDVSSQMNLNSQKMERLS
DMSKSVQETYEKMSANLSSVVLDSNQSMDDYAKSGRQIEAMVSDFIKVEKVASKTLADYSDILKIATHVSETTKNLDKQV
NLFKT

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=301, Percent_Identity=26.9102990033223, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI2367378, Length=275, Percent_Identity=28.7272727272727, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788194, Length=166, Percent_Identity=32.5301204819277, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787690, Length=177, Percent_Identity=32.7683615819209, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788195, Length=67, Percent_Identity=64.1791044776119, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62903; Mature: 62903

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFASIFSSFGARIVLVVLATLLGLGGLSISLVKVMQKDVLEQIMGHLETEQYRKREKTL
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYMTKILEQGIHEYYKNFDNATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCC
TIGQSGISLQSVDGVYYVKGYLEAAKKGGGYTYYKMSKYGGGVPEKKFAYSHYDEVSQMV
CCCCCCCCEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
IAATSYYTDIDAENRAIKEDIEKAFNESTAKLFLWILIATIALAVLTLIYAKLKIVKRID
HHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLVLKINAFSHGDKDLRAKIDVDDRNDEISQVGHGVNLFVEKARLIIEETKGISTLNKTS
HHHHEEECCCCCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
MDKLVQITKETQESMKNSSTTLNSVKDKATDVASVMSASIEQSQGLRKRLIETQGLVKES
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDAIGDLFYQIIEAAHTEEELSNKVEQLSRNADDVKSILDIINDIADQTNLLALNAAIEA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
ARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINDVSSQMNLNSQKMERLS
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DMSKSVQETYEKMSANLSSVVLDSNQSMDDYAKSGRQIEAMVSDFIKVEKVASKTLADYS
HHHHHHHHHHHHHHCCHHHHEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DILKIATHVSETTKNLDKQVNLFKT
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMFASIFSSFGARIVLVVLATLLGLGGLSISLVKVMQKDVLEQIMGHLETEQYRKREKTL
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYMTKILEQGIHEYYKNFDNATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCC
TIGQSGISLQSVDGVYYVKGYLEAAKKGGGYTYYKMSKYGGGVPEKKFAYSHYDEVSQMV
CCCCCCCCEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
IAATSYYTDIDAENRAIKEDIEKAFNESTAKLFLWILIATIALAVLTLIYAKLKIVKRID
HHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLVLKINAFSHGDKDLRAKIDVDDRNDEISQVGHGVNLFVEKARLIIEETKGISTLNKTS
HHHHEEECCCCCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
MDKLVQITKETQESMKNSSTTLNSVKDKATDVASVMSASIEQSQGLRKRLIETQGLVKES
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDAIGDLFYQIIEAAHTEEELSNKVEQLSRNADDVKSILDIINDIADQTNLLALNAAIEA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
ARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINDVSSQMNLNSQKMERLS
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DMSKSVQETYEKMSANLSSVVLDSNQSMDDYAKSGRQIEAMVSDFIKVEKVASKTLADYS
HHHHHHHHHHHHHHCCHHHHEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DILKIATHVSETTKNLDKQVNLFKT
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]