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The map label for this gene is luxS

Identifier: 109947958

GI number: 109947958

Start: 1270023

End: 1270496

Strand: Reverse

Name: luxS

Synonym: Hac_1463

Alternate gene names: 109947958

Gene position: 1270496-1270023 (Counterclockwise)

Preceding gene: 109947959

Following gene: 109947957

Centisome position: 81.76

GC content: 41.77

Gene sequence:

>474_bases
ATGAAAACGCCAAACACAAAAATGAATGTAGAAAGTTTTAATTTGGATCACACCAAAGTCAAAGCCCCCTATGTGCGCAT
AGCCGATCGCAAGAAAGGCATCAATGGGGATTTGATTGTCAAATACGATGTGCGCTTCAAGCAACCCAATCAAGAGCATA
TGGACATGCCAAGCTTGCATTCTTTAGAGCATTTAGTTGCTGAGATTATCCGTAACCATGCTAATTATGTTGTGGATTGG
TCGCCTATGGGTTGTCAAACGGGATTTTATCTCACGGTATTAAACCATGACAATTACACAGAGATTTTAGAGGTTTTAGA
AAAGACGATGCAAGATGTGCTTAAGGCTACAGAAGTGCCTGCCAGCAATGAAAAGCAATGCGGTTGGGCGGCTAACCACA
CTTTAGAGGGTGCCAAGAATTTAGCACACGCCTTTTTATCCAAACGAGATGAGTGGTCTGAAATAGGGATTTAA

Upstream 100 bases:

>100_bases
TGGGGATTGAGCATGAAAAGGATTTGTTAGAAGATTTAGAGCAAGCGTTCGCTAAACTAGGCTAAAGTTTCATCACAATT
TATGGGTAAAGGAATCAAAA

Downstream 100 bases:

>100_bases
GGGGTGATTAGGGGGAGAGTTATGGCAAAATGCCTCCTATCCGATCATAAGCTTCACTATTAAAATAAATTTACATTTAA
ATAAAATTTTTGTTATTTAT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKTPNTKMNVESFNLDHTKVKAPYVRIADRKKGINGDLIVKYDVRFKQPNQEHMDMPSLHSLEHLVAEIIRNHANYVVDW
SPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKATEVPASNEKQCGWAANHTLEGAKNLAHAFLSKRDEWSEIGI

Sequences:

>Translated_157_residues
MKTPNTKMNVESFNLDHTKVKAPYVRIADRKKGINGDLIVKYDVRFKQPNQEHMDMPSLHSLEHLVAEIIRNHANYVVDW
SPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKATEVPASNEKQCGWAANHTLEGAKNLAHAFLSKRDEWSEIGI
>Mature_157_residues
MKTPNTKMNVESFNLDHTKVKAPYVRIADRKKGINGDLIVKYDVRFKQPNQEHMDMPSLHSLEHLVAEIIRNHANYVVDW
SPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKATEVPASNEKQCGWAANHTLEGAKNLAHAFLSKRDEWSEIGI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=146, Percent_Identity=37.6712328767123, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_HELAH (Q17VY9)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_665186.1
- ProteinModelPortal:   Q17VY9
- SMR:   Q17VY9
- STRING:   Q17VY9
- GeneID:   4177626
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1463
- NMPDR:   fig|382638.8.peg.1417
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- PhylomeDB:   Q17VY9
- ProtClustDB:   PRK02260
- BioCyc:   HACI382638:HAC_1463-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17964; Mature: 17964

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPNTKMNVESFNLDHTKVKAPYVRIADRKKGINGDLIVKYDVRFKQPNQEHMDMPSLH
CCCCCCCCCEEECCCCCCEECCCEEEECCCCCCCCCCEEEEEEEEECCCCHHHCCCCCHH
SLEHLVAEIIRNHANYVVDWSPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKATEVP
HHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
ASNEKQCGWAANHTLEGAKNLAHAFLSKRDEWSEIGI
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MKTPNTKMNVESFNLDHTKVKAPYVRIADRKKGINGDLIVKYDVRFKQPNQEHMDMPSLH
CCCCCCCCCEEECCCCCCEECCCEEEECCCCCCCCCCEEEEEEEEECCCCHHHCCCCCHH
SLEHLVAEIIRNHANYVVDWSPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKATEVP
HHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
ASNEKQCGWAANHTLEGAKNLAHAFLSKRDEWSEIGI
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA