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The map label for this gene is ackA

Identifier: 109947804

GI number: 109947804

Start: 1104466

End: 1105668

Strand: Reverse

Name: ackA

Synonym: Hac_1289

Alternate gene names: 109947804

Gene position: 1105668-1104466 (Counterclockwise)

Preceding gene: 109947805

Following gene: 109947803

Centisome position: 71.15

GC content: 42.14

Gene sequence:

>1203_bases
ATGGAAATTTTAGTGTTGAATCTGGGGAGTTCGTCTATTAAGTTTAAATTGTTTGACATGAAAGAAAACAAGCCCTTAGC
GAGCGGTTTGATAGAAAGGATTGGCGAAGAAGTTGGGCAATTGAAAATCCAATCGCATTTGCACCATGACAAGCAGGAAG
TTAAAAAACAGCTTTTCATTAAAGATCATGCGAGCGGGCTTTTAATGGTGCGTGAACATTTAACGAAAATGGGGATCATT
AAGGATTTTGACAAAATTGACGCCATAGGGCATCGTGTGGTCCAAGGGGGGGATAAATTCCATGCACCTGTGTTGGTGGA
TGAAAAAGTGATGCAAGAAATTGAAAGGCTTTCTATTTTAGCCCCCTTGCACAACCCAGTGAATTTAGCCGGTATCAAGT
TTGTCAAAACAGCACACCCTCATATCCCTCAAATTGCGGTTTTTGATACCGCTTTCCATGCCACTATGCCTGATTTTGCT
TACATGTATGCTTTGCCTTATGAATTGTATGAAAAATATCAAATCCGGCGTTATGGTTTCCATGGGACTTCGCACCATTA
TGTCGCTAAAGAAGCGGCAAAATACTTGCATATCCCTTATCATAAATTTAACGCCATCACTTTGCATTTAGGCAATGGTG
CAAGCGTGGCAGCCATAAAAGACGGCAAGAGCGTGGATACTTCTATGGGGCTAACCCCTTTAGAGGGCTTGATTATGGGC
ACAAGGTGTGGGGATATTGACCCTACTGTGGTGGAATACATCGCGCAATGCGCCAATAAGAGTTTAGAAGAAGTGATGAA
AATTTTAAATTATGAGAGCGGTTTGAAAGGTATTTGTGGGGATAATGACGCTAGGAATATTGAAACAAGAGCCAAAAAGG
GCGACAAACAAGCCAAGCTCGCTTTTGAAATGTGTGCATATCGCATTAAAAAGCACATTGGGGCATACATGGTGGCTTTA
GGGAGGGTGGATGCGATCATCTTTACCGGAGGAATGGGGGAAAATTACCCTGCTTTAAGGGAGAGCGTGTGCGAGGGTTT
AGAAAAATTAGGGATTGCTTTACACAAACCCACGAATGATAATCCAGGTAGTGGGATAGTGGATCTAAGCCAACCTAACA
CTAAAATCCAGGTTTTACGCATCCCTACGGATGAAGAGCTAGAAATCGCTTTGCAAACAAAAAGGGTTTTGGAAAAACAC
TAA

Upstream 100 bases:

>100_bases
GAATAAGCCGGTTAATGATTTGAGTAGGGGCGCTTTAGTGGAGGATATTATCAACACGATTTTGATTAGCGCCATTCAAG
CGCAAGATTAGGAGGCATGC

Downstream 100 bases:

>100_bases
TTGTTAAAGCTTTATTTTATTTTTTAAACATAGGTTTTTTTAACTTTATTTTATATAGTAAAAACTCTTAAGGGGTTAAG
GGGGTATTTTGAAATAATCT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MEILVLNLGSSSIKFKLFDMKENKPLASGLIERIGEEVGQLKIQSHLHHDKQEVKKQLFIKDHASGLLMVREHLTKMGII
KDFDKIDAIGHRVVQGGDKFHAPVLVDEKVMQEIERLSILAPLHNPVNLAGIKFVKTAHPHIPQIAVFDTAFHATMPDFA
YMYALPYELYEKYQIRRYGFHGTSHHYVAKEAAKYLHIPYHKFNAITLHLGNGASVAAIKDGKSVDTSMGLTPLEGLIMG
TRCGDIDPTVVEYIAQCANKSLEEVMKILNYESGLKGICGDNDARNIETRAKKGDKQAKLAFEMCAYRIKKHIGAYMVAL
GRVDAIIFTGGMGENYPALRESVCEGLEKLGIALHKPTNDNPGSGIVDLSQPNTKIQVLRIPTDEELEIALQTKRVLEKH

Sequences:

>Translated_400_residues
MEILVLNLGSSSIKFKLFDMKENKPLASGLIERIGEEVGQLKIQSHLHHDKQEVKKQLFIKDHASGLLMVREHLTKMGII
KDFDKIDAIGHRVVQGGDKFHAPVLVDEKVMQEIERLSILAPLHNPVNLAGIKFVKTAHPHIPQIAVFDTAFHATMPDFA
YMYALPYELYEKYQIRRYGFHGTSHHYVAKEAAKYLHIPYHKFNAITLHLGNGASVAAIKDGKSVDTSMGLTPLEGLIMG
TRCGDIDPTVVEYIAQCANKSLEEVMKILNYESGLKGICGDNDARNIETRAKKGDKQAKLAFEMCAYRIKKHIGAYMVAL
GRVDAIIFTGGMGENYPALRESVCEGLEKLGIALHKPTNDNPGSGIVDLSQPNTKIQVLRIPTDEELEIALQTKRVLEKH
>Mature_400_residues
MEILVLNLGSSSIKFKLFDMKENKPLASGLIERIGEEVGQLKIQSHLHHDKQEVKKQLFIKDHASGLLMVREHLTKMGII
KDFDKIDAIGHRVVQGGDKFHAPVLVDEKVMQEIERLSILAPLHNPVNLAGIKFVKTAHPHIPQIAVFDTAFHATMPDFA
YMYALPYELYEKYQIRRYGFHGTSHHYVAKEAAKYLHIPYHKFNAITLHLGNGASVAAIKDGKSVDTSMGLTPLEGLIMG
TRCGDIDPTVVEYIAQCANKSLEEVMKILNYESGLKGICGDNDARNIETRAKKGDKQAKLAFEMCAYRIKKHIGAYMVAL
GRVDAIIFTGGMGENYPALRESVCEGLEKLGIALHKPTNDNPGSGIVDLSQPNTKIQVLRIPTDEELEIALQTKRVLEKH

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=39.8989898989899, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI1788633, Length=399, Percent_Identity=42.3558897243108, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_HELAH (Q17WE3)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_665032.1
- ProteinModelPortal:   Q17WE3
- SMR:   Q17WE3
- STRING:   Q17WE3
- GeneID:   4177694
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1289
- NMPDR:   fig|382638.8.peg.1249
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   YIAQCAN
- PhylomeDB:   Q17WE3
- ProtClustDB:   PRK00180
- BioCyc:   HACI382638:HAC_1289-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 44581; Mature: 44581

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILVLNLGSSSIKFKLFDMKENKPLASGLIERIGEEVGQLKIQSHLHHDKQEVKKQLFI
CEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KDHASGLLMVREHLTKMGIIKDFDKIDAIGHRVVQGGDKFHAPVLVDEKVMQEIERLSIL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHH
APLHNPVNLAGIKFVKTAHPHIPQIAVFDTAFHATMPDFAYMYALPYELYEKYQIRRYGF
HCCCCCCCCCCEEEEECCCCCCCEEEEEHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCC
HGTSHHYVAKEAAKYLHIPYHKFNAITLHLGNGASVAAIKDGKSVDTSMGLTPLEGLIMG
CCCCCHHHHHHHHHHEECCEEECEEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHEEEE
TRCGDIDPTVVEYIAQCANKSLEEVMKILNYESGLKGICGDNDARNIETRAKKGDKQAKL
CCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHH
AFEMCAYRIKKHIGAYMVALGRVDAIIFTGGMGENYPALRESVCEGLEKLGIALHKPTND
HHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCC
NPGSGIVDLSQPNTKIQVLRIPTDEELEIALQTKRVLEKH
CCCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEILVLNLGSSSIKFKLFDMKENKPLASGLIERIGEEVGQLKIQSHLHHDKQEVKKQLFI
CEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KDHASGLLMVREHLTKMGIIKDFDKIDAIGHRVVQGGDKFHAPVLVDEKVMQEIERLSIL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHH
APLHNPVNLAGIKFVKTAHPHIPQIAVFDTAFHATMPDFAYMYALPYELYEKYQIRRYGF
HCCCCCCCCCCEEEEECCCCCCCEEEEEHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCC
HGTSHHYVAKEAAKYLHIPYHKFNAITLHLGNGASVAAIKDGKSVDTSMGLTPLEGLIMG
CCCCCHHHHHHHHHHEECCEEECEEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHEEEE
TRCGDIDPTVVEYIAQCANKSLEEVMKILNYESGLKGICGDNDARNIETRAKKGDKQAKL
CCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHH
AFEMCAYRIKKHIGAYMVALGRVDAIIFTGGMGENYPALRESVCEGLEKLGIALHKPTND
HHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCC
NPGSGIVDLSQPNTKIQVLRIPTDEELEIALQTKRVLEKH
CCCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA