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The map label for this gene is neuA [H]

Identifier: 109947790

GI number: 109947790

Start: 1092030

End: 1092689

Strand: Reverse

Name: neuA [H]

Synonym: Hac_1269

Alternate gene names: 109947790

Gene position: 1092689-1092030 (Counterclockwise)

Preceding gene: 109947791

Following gene: 109947789

Centisome position: 70.32

GC content: 38.03

Gene sequence:

>660_bases
ATGAAAATTTTAGCCTACATTCCTGCCAGAAGCGGTTCTAAAGGGGTGAAAGATAAGAATATTAAACCCTTTAAAGGCTT
GCCTTTGATGGCGCACACAATCCTTAATGCAATGGATGCAAAGCTTTTTGATGAGGTGATGGTAAGTACGGATAGCGAAG
TTTATAGAAAAATCGCTTTAGAATATGGGGCTAAAGCGCCGTTTTTAAGGAGCGAAGAAAATTCAAGCGACACAGCCCTT
ACGATTTTAGGTTTATTGGAGGCTTTAGAAAATTACTCTCAATTAAACAAGCGATTTGATCATGTAATGATCTTGCAACC
CACTTCGCCCTTAAGAGATGCTAGGGATATTTTAAAGGCTTGGGAATGCTATGAGAGAAACCATTTTCAAAGTTTAGCGA
GCGTGCATAAAATAGAGATCAACCCCTTTTTATTACGCACCCTTAAAAACGATCAGCTCTCTTCTTTAATGCAAGTCAAT
AGCACTATCAGGCGCCAGGACATGCCTGTTTTTTATCAAGTCAATGGTGCAATTTATATTGCTAAAGTGAGCGAATTGAA
CGAAAAAACGAGTTTGAATGACAGCGTGATAGGGCATGAAATAGAAATTTCTCATGCCCTAGATATAGACAATTTAAAGG
ATTTTGATGGGTACAATTAA

Upstream 100 bases:

>100_bases
TTGGTCAAGGCGATAGCGCTAAGCGGTTTTTAGCGAGTTTGAATTTAGAATTGTTTGACACGCCTACGCAAAAAAGCTTT
GTGATAAGGGAGGTGAAAGG

Downstream 100 bases:

>100_bases
AAAACCCTTAATCATTGCCGGCAACGGTCCTAGCATTAAGGATTTAGATTATGCATTATTCCCTAAAGATTTTGATGTCT
TTAGGTGCAACCAATTTTAT

Product: N-acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKILAYIPARSGSKGVKDKNIKPFKGLPLMAHTILNAMDAKLFDEVMVSTDSEVYRKIALEYGAKAPFLRSEENSSDTAL
TILGLLEALENYSQLNKRFDHVMILQPTSPLRDARDILKAWECYERNHFQSLASVHKIEINPFLLRTLKNDQLSSLMQVN
STIRRQDMPVFYQVNGAIYIAKVSELNEKTSLNDSVIGHEIEISHALDIDNLKDFDGYN

Sequences:

>Translated_219_residues
MKILAYIPARSGSKGVKDKNIKPFKGLPLMAHTILNAMDAKLFDEVMVSTDSEVYRKIALEYGAKAPFLRSEENSSDTAL
TILGLLEALENYSQLNKRFDHVMILQPTSPLRDARDILKAWECYERNHFQSLASVHKIEINPFLLRTLKNDQLSSLMQVN
STIRRQDMPVFYQVNGAIYIAKVSELNEKTSLNDSVIGHEIEISHALDIDNLKDFDGYN
>Mature_219_residues
MKILAYIPARSGSKGVKDKNIKPFKGLPLMAHTILNAMDAKLFDEVMVSTDSEVYRKIALEYGAKAPFLRSEENSSDTAL
TILGLLEALENYSQLNKRFDHVMILQPTSPLRDARDILKAWECYERNHFQSLASVHKIEINPFLLRTLKNDQLSSLMQVN
STIRRQDMPVFYQVNGAIYIAKVSELNEKTSLNDSVIGHEIEISHALDIDNLKDFDGYN

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=212, Percent_Identity=28.7735849056604, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087 [H]

Pfam domain/function: PF02348 CTP_transf_3; PF00657 Lipase_GDSL [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 24876; Mature: 24876

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILAYIPARSGSKGVKDKNIKPFKGLPLMAHTILNAMDAKLFDEVMVSTDSEVYRKIAL
CEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EYGAKAPFLRSEENSSDTALTILGLLEALENYSQLNKRFDHVMILQPTSPLRDARDILKA
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHH
WECYERNHFQSLASVHKIEINPFLLRTLKNDQLSSLMQVNSTIRRQDMPVFYQVNGAIYI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEE
AKVSELNEKTSLNDSVIGHEIEISHALDIDNLKDFDGYN
EEEHHCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKILAYIPARSGSKGVKDKNIKPFKGLPLMAHTILNAMDAKLFDEVMVSTDSEVYRKIAL
CEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EYGAKAPFLRSEENSSDTALTILGLLEALENYSQLNKRFDHVMILQPTSPLRDARDILKA
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHH
WECYERNHFQSLASVHKIEINPFLLRTLKNDQLSSLMQVNSTIRRQDMPVFYQVNGAIYI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEE
AKVSELNEKTSLNDSVIGHEIEISHALDIDNLKDFDGYN
EEEHHCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10464185 [H]