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The map label for this gene is ribA [H]

Identifier: 109947472

GI number: 109947472

Start: 808924

End: 809958

Strand: Reverse

Name: ribA [H]

Synonym: Hac_0924

Alternate gene names: 109947472

Gene position: 809958-808924 (Counterclockwise)

Preceding gene: 109947473

Following gene: 109947471

Centisome position: 52.12

GC content: 38.36

Gene sequence:

>1035_bases
ATGGTTTTAAAACGAGTTACTGAAGCATTAGAAGCGTATAAAAATGGCGAAATGCTTATTGTCATGGACGATGAAGACAG
AGAAAATGAGGGGGATTTGGTTTTAGCGGGGATTTTTTCTACCCCTGAAAAAATCAATTTCATGGCCACGCATGCTAGGG
GGTTAATCTGTGTGTCTTTAACCAAAGATTTAGCGAAAAAATTTGAATTACCCCCTATGGTTAGCGTGAATGATTCTAAT
CATGAAACCGCTTTCACGGTATCTATTGACGCTAAAGAAGCCAAAACCGGGATTTCTGCTTTTGAAAGGCATTTAACGAT
TGAATTGCTTTGTAAAGACACGACTAGACCTAGCGATTTTGTGCGCCCGGGGCATATTTTCCCTTTGATCGCTAAAGATG
GAGGCGTTTTAGCGCGCACAGGCCATACCGAAGCGAGCGTAGATTTATGCAAATTGGCTGGATTAAAACCGGTGAGCGTG
ATTTGTGAAATCATGAAAGAAGATGGCTCTATGGCGAGAAGAGAGGATAAATTTTTGAGCGATTTTGCCCTTAAACACAA
CCTTAAAACCCTTTATATCTCTGATTTGATTAGCTATCGTTTGGAAAATGAAAATTTGCTTAAAATGTTTTGTCAAGAAG
AAAGAGAATTTTTAAAACACCAGACGCAATGCTACACTTTTTTAGACCACCAACAAAAAAACCACTACGCTTTTAAGTTT
AAAGGCACAAAAGCCAATCATTTAGCCCCTTTAGTGCGTTTCCACCCTATTAAAGAGGATTTTGATTTTTTAACGACTGG
TGCGTTTGATGTGTTTTTTAAAGCGTTAGAGTATTTGAAGCGCGAAGGAGGTTACTTGATTTTTATGAACACGCATGCGA
GAGAAAACGAAGTGGTGAAAGATTTTGGGATTGGGGCGTTAGTGTTAAAAAATCTTGGAATAAAGGATTTTAGGCTTTTA
AGCTCTTCTGAAGATAGGCATTATAAGGCTTTGAGCGGATTTGGACTTAAACTTACAGAAACGATTAGTCTTTAA

Upstream 100 bases:

>100_bases
CCTAACCAAATAATCAAGTAATAATCGTTATTAAACATGCTATATTTCTTATTTTTTAACACTCAATATTAATATTATTG
AATGAAATTAGGGAGTTAGA

Downstream 100 bases:

>100_bases
GGCTTGTTGCATTTATTGAGTATACGGTGGTGTTTTTAAGATACAATACAATCTTTTAAGTTAAGTAGTAAAGTTTATAG
GCTAATGAAAACCATCATAA

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MVLKRVTEALEAYKNGEMLIVMDDEDRENEGDLVLAGIFSTPEKINFMATHARGLICVSLTKDLAKKFELPPMVSVNDSN
HETAFTVSIDAKEAKTGISAFERHLTIELLCKDTTRPSDFVRPGHIFPLIAKDGGVLARTGHTEASVDLCKLAGLKPVSV
ICEIMKEDGSMARREDKFLSDFALKHNLKTLYISDLISYRLENENLLKMFCQEEREFLKHQTQCYTFLDHQQKNHYAFKF
KGTKANHLAPLVRFHPIKEDFDFLTTGAFDVFFKALEYLKREGGYLIFMNTHARENEVVKDFGIGALVLKNLGIKDFRLL
SSSEDRHYKALSGFGLKLTETISL

Sequences:

>Translated_344_residues
MVLKRVTEALEAYKNGEMLIVMDDEDRENEGDLVLAGIFSTPEKINFMATHARGLICVSLTKDLAKKFELPPMVSVNDSN
HETAFTVSIDAKEAKTGISAFERHLTIELLCKDTTRPSDFVRPGHIFPLIAKDGGVLARTGHTEASVDLCKLAGLKPVSV
ICEIMKEDGSMARREDKFLSDFALKHNLKTLYISDLISYRLENENLLKMFCQEEREFLKHQTQCYTFLDHQQKNHYAFKF
KGTKANHLAPLVRFHPIKEDFDFLTTGAFDVFFKALEYLKREGGYLIFMNTHARENEVVKDFGIGALVLKNLGIKDFRLL
SSSEDRHYKALSGFGLKLTETISL
>Mature_344_residues
MVLKRVTEALEAYKNGEMLIVMDDEDRENEGDLVLAGIFSTPEKINFMATHARGLICVSLTKDLAKKFELPPMVSVNDSN
HETAFTVSIDAKEAKTGISAFERHLTIELLCKDTTRPSDFVRPGHIFPLIAKDGGVLARTGHTEASVDLCKLAGLKPVSV
ICEIMKEDGSMARREDKFLSDFALKHNLKTLYISDLISYRLENENLLKMFCQEEREFLKHQTQCYTFLDHQQKNHYAFKF
KGTKANHLAPLVRFHPIKEDFDFLTTGAFDVFFKALEYLKREGGYLIFMNTHARENEVVKDFGIGALVLKNLGIKDFRLL
SSSEDRHYKALSGFGLKLTETISL

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=202, Percent_Identity=45.5445544554455, Blast_Score=187, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=42.3645320197044, Blast_Score=164, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 39039; Mature: 39039

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLKRVTEALEAYKNGEMLIVMDDEDRENEGDLVLAGIFSTPEKINFMATHARGLICVSL
CHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEEH
TKDLAKKFELPPMVSVNDSNHETAFTVSIDAKEAKTGISAFERHLTIELLCKDTTRPSDF
HHHHHHHCCCCCEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHEEEEEEECCCCCCHHC
VRPGHIFPLIAKDGGVLARTGHTEASVDLCKLAGLKPVSVICEIMKEDGSMARREDKFLS
CCCCCEEEEEECCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHH
DFALKHNLKTLYISDLISYRLENENLLKMFCQEEREFLKHQTQCYTFLDHQQKNHYAFKF
HHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
KGTKANHLAPLVRFHPIKEDFDFLTTGAFDVFFKALEYLKREGGYLIFMNTHARENEVVK
ECCCCHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
DFGIGALVLKNLGIKDFRLLSSSEDRHYKALSGFGLKLTETISL
HHCCHHHHHHHCCCCCEEEECCCCCCHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MVLKRVTEALEAYKNGEMLIVMDDEDRENEGDLVLAGIFSTPEKINFMATHARGLICVSL
CHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEEH
TKDLAKKFELPPMVSVNDSNHETAFTVSIDAKEAKTGISAFERHLTIELLCKDTTRPSDF
HHHHHHHCCCCCEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHEEEEEEECCCCCCHHC
VRPGHIFPLIAKDGGVLARTGHTEASVDLCKLAGLKPVSVICEIMKEDGSMARREDKFLS
CCCCCEEEEEECCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHH
DFALKHNLKTLYISDLISYRLENENLLKMFCQEEREFLKHQTQCYTFLDHQQKNHYAFKF
HHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
KGTKANHLAPLVRFHPIKEDFDFLTTGAFDVFFKALEYLKREGGYLIFMNTHARENEVVK
ECCCCHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
DFGIGALVLKNLGIKDFRLLSSSEDRHYKALSGFGLKLTETISL
HHCCHHHHHHHCCCCCEEEECCCCCCHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]