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The map label for this gene is dapB

Identifier: 109947446

GI number: 109947446

Start: 781200

End: 781964

Strand: Reverse

Name: dapB

Synonym: Hac_0897

Alternate gene names: 109947446

Gene position: 781964-781200 (Counterclockwise)

Preceding gene: 109947447

Following gene: 109947444

Centisome position: 50.32

GC content: 39.48

Gene sequence:

>765_bases
ATGAAAATCGGTGTTTATGGAGCGAGCGGTCGTATAGGGAAATTACTCTTAGAAGAATTGAAAGGGGGGTATAAAGGATT
AGTGCTATCTAGCGTGTTTGTGCGGCAAAAATGCGAAATAGATTTTAGCTCTTTTTCACACAAACCCCTAGTAACCAATG
ATTTAAAAGCGTTTGTGAGAGCTTGCGAATGCGTGATTGATTTTTCTCTACCTAAAGGTGTGGATAGCTTGCTAGACACT
CTTTTAGAATGCCCTAAAATTTTAGTCTCTGGCACAACCGGTTTGGAAGAAAAAACGCTAGAAAAAATGCAAAATTTAGC
CCTAAAAACGCCGCTTTTGCATGCACACAACATGTCTATTGGGATCGCTATTCTTAATCAATTAGCCTTTTTAGCTTCTT
TGAAATTAAAAGATGCGGATATTGAAATTGTAGAAACACACCATAATCTTAAAAAAGATGCTCCGAGTGGCACTGCGTTG
AGTTTGTATCAAACTTGTGCTAAGGCTAGGGGGTATGATGAAAAAAACGCTCTTACCACTCATAGGGAAGGTTTGCGCTC
TAAAGAAAGTATTGGCGTAGCCGCTTTAAGGGGGGGCGATGTCGCTGGAAAGCACACGATAGGGTTTTATTTAGAAGGCG
AATACATAGAGCTTAGCCATACAGCGACCAATCGTTCTATTTTTGCTAAAGGGGCTTTAGAAGTGGCTCTATGGCTTAAA
GATAAAGCTGCTAAAAAATATGAAATCAACGAGATTTTTGATTGA

Upstream 100 bases:

>100_bases
GTGAAATGGAGCTTTTTAGGAATATTAAAAAAGCCCTTGATCCTAATAATATTTTAAACCCTTTTAAAATGGGGTTGTAA
AAATAAAACAAGGAAGTCGC

Downstream 100 bases:

>100_bases
AATGAGTCCTTTTATAAAATAGTTAAAGCGTTTCTTAATCCCACTCAATGGTAGGTTTTAAAATGCGATTTTGATTGGTT
TTGGTTTCATTTACTTTTTG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKIGVYGASGRIGKLLLEELKGGYKGLVLSSVFVRQKCEIDFSSFSHKPLVTNDLKAFVRACECVIDFSLPKGVDSLLDT
LLECPKILVSGTTGLEEKTLEKMQNLALKTPLLHAHNMSIGIAILNQLAFLASLKLKDADIEIVETHHNLKKDAPSGTAL
SLYQTCAKARGYDEKNALTTHREGLRSKESIGVAALRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLK
DKAAKKYEINEIFD

Sequences:

>Translated_254_residues
MKIGVYGASGRIGKLLLEELKGGYKGLVLSSVFVRQKCEIDFSSFSHKPLVTNDLKAFVRACECVIDFSLPKGVDSLLDT
LLECPKILVSGTTGLEEKTLEKMQNLALKTPLLHAHNMSIGIAILNQLAFLASLKLKDADIEIVETHHNLKKDAPSGTAL
SLYQTCAKARGYDEKNALTTHREGLRSKESIGVAALRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLK
DKAAKKYEINEIFD
>Mature_254_residues
MKIGVYGASGRIGKLLLEELKGGYKGLVLSSVFVRQKCEIDFSSFSHKPLVTNDLKAFVRACECVIDFSLPKGVDSLLDT
LLECPKILVSGTTGLEEKTLEKMQNLALKTPLLHAHNMSIGIAILNQLAFLASLKLKDADIEIVETHHNLKKDAPSGTAL
SLYQTCAKARGYDEKNALTTHREGLRSKESIGVAALRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLK
DKAAKKYEINEIFD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=265, Percent_Identity=31.6981132075472, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_HELAH (Q17XF1)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664674.1
- ProteinModelPortal:   Q17XF1
- SMR:   Q17XF1
- STRING:   Q17XF1
- GeneID:   4176402
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0897
- NMPDR:   fig|382638.8.peg.871
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GALKACE
- PhylomeDB:   Q17XF1
- ProtClustDB:   PRK00048
- BioCyc:   HACI382638:HAC_0897-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27779; Mature: 27779

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVYGASGRIGKLLLEELKGGYKGLVLSSVFVRQKCEIDFSSFSHKPLVTNDLKAFVR
CEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHH
ACECVIDFSLPKGVDSLLDTLLECPKILVSGTTGLEEKTLEKMQNLALKTPLLHAHNMSI
HHHHHHCCCCCCCHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHCCCCEECCCCHH
GIAILNQLAFLASLKLKDADIEIVETHHNLKKDAPSGTALSLYQTCAKARGYDEKNALTT
HHHHHHHHHHHHHHCCCCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
HREGLRSKESIGVAALRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLK
HHHHCCCHHHCCEEEEECCCCCCCCEEEEEEECCEEEEEECCCCCEEEECCCEEEEEEEH
DKAAKKYEINEIFD
HHCCCCCCHHHHCC
>Mature Secondary Structure
MKIGVYGASGRIGKLLLEELKGGYKGLVLSSVFVRQKCEIDFSSFSHKPLVTNDLKAFVR
CEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHH
ACECVIDFSLPKGVDSLLDTLLECPKILVSGTTGLEEKTLEKMQNLALKTPLLHAHNMSI
HHHHHHCCCCCCCHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHCCCCEECCCCHH
GIAILNQLAFLASLKLKDADIEIVETHHNLKKDAPSGTALSLYQTCAKARGYDEKNALTT
HHHHHHHHHHHHHHCCCCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
HREGLRSKESIGVAALRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLK
HHHHCCCHHHCCEEEEECCCCCCCCEEEEEEECCEEEEEECCCCCEEEECCCEEEEEEEH
DKAAKKYEINEIFD
HHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA