| Definition | Helicobacter acinonychis str. Sheeba chromosome, complete genome. |
|---|---|
| Accession | NC_008229 |
| Length | 1,553,927 |
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The map label for this gene is nrdA [H]
Identifier: 109947415
GI number: 109947415
Start: 751053
End: 753419
Strand: Reverse
Name: nrdA [H]
Synonym: Hac_0862
Alternate gene names: 109947415
Gene position: 753419-751053 (Counterclockwise)
Preceding gene: 109947416
Following gene: 109947414
Centisome position: 48.48
GC content: 38.91
Gene sequence:
>2367_bases TTGATTACAGTAGTTAAACGAAACGGGCGCATTGAGCCTTTGGACATTACAAAAATCCAAAAATACACTAAAGACGCTAC GGACAATTTAGAGGGCGTGAGCCAAAGTGAGCTGGAAGTGGATGCAAGGTTGCAATTTAGAGACAAGATTACTACTGAAG AAATCCAACAAACTTTGATTAAAACCGCTGTGGATAAGATAGATATTGACACGCCTAATTGGAGCTTTGTCGCCTCAAGA CTTTTTTTATATGATTTATATCATAAAGTGAGCGGTTTTACAGGATATAGGCATTTGAAAGAGTATTTTGAAAACGCTGA AGAAAAGGGCCGTATCCTTAAGGGCTTTAAGGAAAAATTTGATTTGGAGTTTTTAAATAGCCAGATCAAGCCTGAAAGGG ATTTTCAATTCAATTACTTGGGGATTAAAACCTTGTATGATCGCTATTTGTTGAAAGATGCCAACAATTACCCTATTGAA TTACCTCAGCATATGTTTATGAGTATTGCGATGTTTTTAGCGCAAAACGAACAAGAACCTAATAAAATCGCTTTGGAATT TTATGAAGTCTTAAGCAAATTTGAAGCGATGTGTGCGACCCCCACTTTAGCGAACGCTCGCACCACCAAGCACCAGCTAA GCTCATGCTATATTGGCAGCACACCGGATAATATTGAAGGGATTTTTGATAGCTATAAGGAAATGGCGTTGTTATCCAAA TACGGTGGGGGGATTGGTTGGGATTTTTCTTTGGTGCGCTCTATTGGGAGTTATATTGATGGGTATAAAAATGCGAGCGC TGGCACGATCCCCTTTTTAAAAATCGCTAATGATGTGGCGATTGCGGTTGATCAATTAGGCACACGAAAGGGTGCGATTG CGGTGTATTTGGAAATCTGGCACATTGATGTGATGGAGTTCATTGATTTAAGAAAAAATAGTGGCGATGAAAGAAGAAGA GCGCATGATTTATTTCCGGCTCTTTGGGTGTGTGATTTGTTCATGAAAAGGGTTTTAGAAGATGCGATATGGACTTTGTT TGACCCTTATGAGTGTAAGGATCTCTCTGAACTTTATGGGCAAGAGTTTGAAAAACGCTACTTAGAGTATGAAAAAGATC CTAAAATCATTAAAGAATACATTAACGCTAAAGATTTATGGAAAAAAATCTTAATGAATTATTTTGAAGCCGGCTTGCCT TTCTTGGCTTTTAAAGACAACGCTAATCGGTGCAATCCAAACGCCCATACAGGTATTATTAGATCAAGCAATCTATGCAC GGAGATCTTTCAAAATACCGCACCCAACCACTATTACATGCAAATAGAATACACCGATGGCACTATGGATTTTTTTGAAG AAAAGCAGTTGGTAACCACAGATAGTAATATCACTAAATGCGCTAACAAGCTCACCAGCACGGATATTCTTAAAGGCAAA CAAATCTATATCGCTACTAAAATCGCCAAAGATGGGCAAACGGCGGTGTGCAATTTAGCGAGTATCAATTTAAGCAAGAT CAACACTGAAGAAGACATTAAAAGAGTCGTGCCGATTATGGTCAGGCTATTAGATAATGTGATTGATTTGAATTTTTATC CTAACCGCAAAGTCAAAGCCACCAATTTGCAAAATAGAGCCATAGGGTTAGGGGTTATGGGTGAAGCGCAAATGCTTGCA GAACATAAAATCGCTTGGGGGTCTAAAGAGCATTTAGAAAAAATTGACGCTTTAATGGAGCAAATCAGCTACCATGCGAT TGATACGAGCGTGAATCTAGCGAAAGAAAAAGGGGTTTATAAGGACTTTGAAAATTCAGAATGGAGTAAGGGGATTTTCC CTATTGATAAAGCGAATAAAGAAGCCTTAAAGCTCACCGAAAAAGGGCTTTTTAATTACGCTTGCGATTGGCAGGGTTTG AGGGAAAAAGTCAAAACTTTTGGCATGCGTAATGGCTATTTAATGGCGATCGCTCCTACTAGCTCTATTTCTATTTTAGT AGGCACAACCCAAACAATTGAACCTATTTATAAGAAAAAATGGTTTGAAGAAAATTTGAGCGGGCTTATTCCAGTCGTTG TGCCTAATTTAAGCGTAGAAACTTGGAATTTTTACACATCAGCCTATGATATTGACGCTAAAGATTTGATCAGAGCGGCA GCCGTGCGCCAAAAATGGATCGATCAAGGGCAAAGCATTAATGTGTTTTTACGCGTAGAAAACGCTAGCGGTAAAACCTT GCATGAAATCTACACGCTCGCTTGGAAATTAGGGTTAAAATCCACTTATTATTTGCGTAGCGAAAGCCCTAGCATTGATG AAAAAAGTGTGTTGGATCGCTCGGTAGAATGCCATAATTGCCAATGA
Upstream 100 bases:
>100_bases TAAAACAAGAAATCTTAAGGCGTAGTTTTTTTTAAGCACTTTGTTATTATAATTCCGAATTTAAAAAACAAACGATTTAA TTCAAATTTAAGGATAAGTT
Downstream 100 bases:
>100_bases TATAAGCTTAAATAAGCTAATCTTTTGCTAACATAAGATTAAAATTCTTGAAGGAAGATAAATGCTTTTTGCTATGATTG GTTCAGGGGGGTTTATCGCT
Product: ribonucleotide-diphosphate reductase subunit alpha
Products: NA
Alternate protein names: Ribonucleotide reductase [H]
Number of amino acids: Translated: 788; Mature: 788
Protein sequence:
>788_residues MITVVKRNGRIEPLDITKIQKYTKDATDNLEGVSQSELEVDARLQFRDKITTEEIQQTLIKTAVDKIDIDTPNWSFVASR LFLYDLYHKVSGFTGYRHLKEYFENAEEKGRILKGFKEKFDLEFLNSQIKPERDFQFNYLGIKTLYDRYLLKDANNYPIE LPQHMFMSIAMFLAQNEQEPNKIALEFYEVLSKFEAMCATPTLANARTTKHQLSSCYIGSTPDNIEGIFDSYKEMALLSK YGGGIGWDFSLVRSIGSYIDGYKNASAGTIPFLKIANDVAIAVDQLGTRKGAIAVYLEIWHIDVMEFIDLRKNSGDERRR AHDLFPALWVCDLFMKRVLEDAIWTLFDPYECKDLSELYGQEFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLP FLAFKDNANRCNPNAHTGIIRSSNLCTEIFQNTAPNHYYMQIEYTDGTMDFFEEKQLVTTDSNITKCANKLTSTDILKGK QIYIATKIAKDGQTAVCNLASINLSKINTEEDIKRVVPIMVRLLDNVIDLNFYPNRKVKATNLQNRAIGLGVMGEAQMLA EHKIAWGSKEHLEKIDALMEQISYHAIDTSVNLAKEKGVYKDFENSEWSKGIFPIDKANKEALKLTEKGLFNYACDWQGL REKVKTFGMRNGYLMAIAPTSSISILVGTTQTIEPIYKKKWFEENLSGLIPVVVPNLSVETWNFYTSAYDIDAKDLIRAA AVRQKWIDQGQSINVFLRVENASGKTLHEIYTLAWKLGLKSTYYLRSESPSIDEKSVLDRSVECHNCQ
Sequences:
>Translated_788_residues MITVVKRNGRIEPLDITKIQKYTKDATDNLEGVSQSELEVDARLQFRDKITTEEIQQTLIKTAVDKIDIDTPNWSFVASR LFLYDLYHKVSGFTGYRHLKEYFENAEEKGRILKGFKEKFDLEFLNSQIKPERDFQFNYLGIKTLYDRYLLKDANNYPIE LPQHMFMSIAMFLAQNEQEPNKIALEFYEVLSKFEAMCATPTLANARTTKHQLSSCYIGSTPDNIEGIFDSYKEMALLSK YGGGIGWDFSLVRSIGSYIDGYKNASAGTIPFLKIANDVAIAVDQLGTRKGAIAVYLEIWHIDVMEFIDLRKNSGDERRR AHDLFPALWVCDLFMKRVLEDAIWTLFDPYECKDLSELYGQEFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLP FLAFKDNANRCNPNAHTGIIRSSNLCTEIFQNTAPNHYYMQIEYTDGTMDFFEEKQLVTTDSNITKCANKLTSTDILKGK QIYIATKIAKDGQTAVCNLASINLSKINTEEDIKRVVPIMVRLLDNVIDLNFYPNRKVKATNLQNRAIGLGVMGEAQMLA EHKIAWGSKEHLEKIDALMEQISYHAIDTSVNLAKEKGVYKDFENSEWSKGIFPIDKANKEALKLTEKGLFNYACDWQGL REKVKTFGMRNGYLMAIAPTSSISILVGTTQTIEPIYKKKWFEENLSGLIPVVVPNLSVETWNFYTSAYDIDAKDLIRAA AVRQKWIDQGQSINVFLRVENASGKTLHEIYTLAWKLGLKSTYYLRSESPSIDEKSVLDRSVECHNCQ >Mature_788_residues MITVVKRNGRIEPLDITKIQKYTKDATDNLEGVSQSELEVDARLQFRDKITTEEIQQTLIKTAVDKIDIDTPNWSFVASR LFLYDLYHKVSGFTGYRHLKEYFENAEEKGRILKGFKEKFDLEFLNSQIKPERDFQFNYLGIKTLYDRYLLKDANNYPIE LPQHMFMSIAMFLAQNEQEPNKIALEFYEVLSKFEAMCATPTLANARTTKHQLSSCYIGSTPDNIEGIFDSYKEMALLSK YGGGIGWDFSLVRSIGSYIDGYKNASAGTIPFLKIANDVAIAVDQLGTRKGAIAVYLEIWHIDVMEFIDLRKNSGDERRR AHDLFPALWVCDLFMKRVLEDAIWTLFDPYECKDLSELYGQEFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLP FLAFKDNANRCNPNAHTGIIRSSNLCTEIFQNTAPNHYYMQIEYTDGTMDFFEEKQLVTTDSNITKCANKLTSTDILKGK QIYIATKIAKDGQTAVCNLASINLSKINTEEDIKRVVPIMVRLLDNVIDLNFYPNRKVKATNLQNRAIGLGVMGEAQMLA EHKIAWGSKEHLEKIDALMEQISYHAIDTSVNLAKEKGVYKDFENSEWSKGIFPIDKANKEALKLTEKGLFNYACDWQGL REKVKTFGMRNGYLMAIAPTSSISILVGTTQTIEPIYKKKWFEENLSGLIPVVVPNLSVETWNFYTSAYDIDAKDLIRAA AVRQKWIDQGQSINVFLRVENASGKTLHEIYTLAWKLGLKSTYYLRSESPSIDEKSVLDRSVECHNCQ
Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]
COG id: COG0209
COG function: function code F; Ribonucleotide reductase, alpha subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-cone domain [H]
Homologues:
Organism=Homo sapiens, GI4506749, Length=813, Percent_Identity=33.5793357933579, Blast_Score=381, Evalue=1e-105, Organism=Escherichia coli, GI2367133, Length=805, Percent_Identity=26.832298136646, Blast_Score=288, Evalue=8e-79, Organism=Escherichia coli, GI1789030, Length=671, Percent_Identity=29.3591654247392, Blast_Score=266, Evalue=4e-72, Organism=Caenorhabditis elegans, GI17555242, Length=817, Percent_Identity=30.2325581395349, Blast_Score=337, Evalue=1e-92, Organism=Saccharomyces cerevisiae, GI6320914, Length=830, Percent_Identity=33.1325301204819, Blast_Score=385, Evalue=1e-107, Organism=Saccharomyces cerevisiae, GI6322123, Length=822, Percent_Identity=31.6301703163017, Blast_Score=376, Evalue=1e-105, Organism=Drosophila melanogaster, GI17352481, Length=816, Percent_Identity=32.5980392156863, Blast_Score=367, Evalue=1e-101,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005144 - InterPro: IPR013346 - InterPro: IPR013509 - InterPro: IPR000788 - InterPro: IPR008926 [H]
Pfam domain/function: PF03477 ATP-cone; PF02867 Ribonuc_red_lgC; PF00317 Ribonuc_red_lgN [H]
EC number: =1.17.4.1 [H]
Molecular weight: Translated: 90436; Mature: 90436
Theoretical pI: Translated: 6.24; Mature: 6.24
Prosite motif: PS51161 ATP_CONE ; PS00089 RIBORED_LARGE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MITVVKRNGRIEPLDITKIQKYTKDATDNLEGVSQSELEVDARLQFRDKITTEEIQQTLI CEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH KTAVDKIDIDTPNWSFVASRLFLYDLYHKVSGFTGYRHLKEYFENAEEKGRILKGFKEKF HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHCCHHHHHHHHHH DLEFLNSQIKPERDFQFNYLGIKTLYDRYLLKDANNYPIELPQHMFMSIAMFLAQNEQEP HHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC NKIALEFYEVLSKFEAMCATPTLANARTTKHQLSSCYIGSTPDNIEGIFDSYKEMALLSK HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH YGGGIGWDFSLVRSIGSYIDGYKNASAGTIPFLKIANDVAIAVDQLGTRKGAIAVYLEIW HCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCEEEEEEEH HIDVMEFIDLRKNSGDERRRAHDLFPALWVCDLFMKRVLEDAIWTLFDPYECKDLSELYG HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH QEFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLPFLAFKDNANRCNPNAHTGII HHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEE RSSNLCTEIFQNTAPNHYYMQIEYTDGTMDFFEEKQLVTTDSNITKCANKLTSTDILKGK ECCHHHHHHHHCCCCCEEEEEEEEECCCHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCC QIYIATKIAKDGQTAVCNLASINLSKINTEEDIKRVVPIMVRLLDNVIDLNFYPNRKVKA EEEEEEEECCCCCCEEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE TNLQNRAIGLGVMGEAQMLAEHKIAWGSKEHLEKIDALMEQISYHAIDTSVNLAKEKGVY CCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC KDFENSEWSKGIFPIDKANKEALKLTEKGLFNYACDWQGLREKVKTFGMRNGYLMAIAPT CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECC SSISILVGTTQTIEPIYKKKWFEENLSGLIPVVVPNLSVETWNFYTSAYDIDAKDLIRAA CCEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEEEEEECCCHHHHHHHH AVRQKWIDQGQSINVFLRVENASGKTLHEIYTLAWKLGLKSTYYLRSESPSIDEKSVLDR HHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHC SVECHNCQ CCCCCCCC >Mature Secondary Structure MITVVKRNGRIEPLDITKIQKYTKDATDNLEGVSQSELEVDARLQFRDKITTEEIQQTLI CEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH KTAVDKIDIDTPNWSFVASRLFLYDLYHKVSGFTGYRHLKEYFENAEEKGRILKGFKEKF HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHCCHHHHHHHHHH DLEFLNSQIKPERDFQFNYLGIKTLYDRYLLKDANNYPIELPQHMFMSIAMFLAQNEQEP HHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC NKIALEFYEVLSKFEAMCATPTLANARTTKHQLSSCYIGSTPDNIEGIFDSYKEMALLSK HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH YGGGIGWDFSLVRSIGSYIDGYKNASAGTIPFLKIANDVAIAVDQLGTRKGAIAVYLEIW HCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCEEEEEEEH HIDVMEFIDLRKNSGDERRRAHDLFPALWVCDLFMKRVLEDAIWTLFDPYECKDLSELYG HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH QEFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLPFLAFKDNANRCNPNAHTGII HHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEE RSSNLCTEIFQNTAPNHYYMQIEYTDGTMDFFEEKQLVTTDSNITKCANKLTSTDILKGK ECCHHHHHHHHCCCCCEEEEEEEEECCCHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCC QIYIATKIAKDGQTAVCNLASINLSKINTEEDIKRVVPIMVRLLDNVIDLNFYPNRKVKA EEEEEEEECCCCCCEEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE TNLQNRAIGLGVMGEAQMLAEHKIAWGSKEHLEKIDALMEQISYHAIDTSVNLAKEKGVY CCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC KDFENSEWSKGIFPIDKANKEALKLTEKGLFNYACDWQGLREKVKTFGMRNGYLMAIAPT CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECC SSISILVGTTQTIEPIYKKKWFEENLSGLIPVVVPNLSVETWNFYTSAYDIDAKDLIRAA CCEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEEEEEECCCHHHHHHHH AVRQKWIDQGQSINVFLRVENASGKTLHEIYTLAWKLGLKSTYYLRSESPSIDEKSVLDR HHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHC SVECHNCQ CCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9923682 [H]