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The map label for this gene is aspB [H]

Identifier: 109947306

GI number: 109947306

Start: 645835

End: 646962

Strand: Direct

Name: aspB [H]

Synonym: Hac_0736

Alternate gene names: 109947306

Gene position: 645835-646962 (Clockwise)

Preceding gene: 109947300

Following gene: 109947307

Centisome position: 41.56

GC content: 37.41

Gene sequence:

>1128_bases
ATGACCTTTGAGCCTTATCCTTTTGAACGATTAAGAGCCTTGTTTAAAGAAATTACCCCTAAAAAAAAGGGGTTAGATTT
AAGCATCGGTGAGCCACGATTTGAAACGCCTAAATTCATTCAGGACGCCCTTAAACAACACGCTAATTCGCTTAATATCT
ACCCTAAAAGCACGTTTGAAGAGAGTTTAAGGGCGGCTCAAAGGGATTTTTTTAAACGCCGTTTTAAGATAGAATTGAAA
GAAAACGAGCTTATCTCCACGCTAGGCTCTAGAGAAGTGTTGTTTAATTTCCCCAGTTTTGTTTTATTTGATTACCAAAA
CCCCACTATCGCTTATCCTAACCCCTTTTATCAAATCTATGAAGGGGCGGCTCAATTTGCTAGAGCTAAAAGCCTTTTAA
TGCCTTTAGTAAAAGAAAATGATTTCACTCCAATCTTGAATGAAAAAGAGTTGCAAGAAGTGGATTTAGTGATCTTAAAT
TCCCCTAATAACCCCACAGGAAGAACCCTTTCTTTAGAAGAATTGCATGCTTGGGTCAGACTCGCTTTAAAATATGATTT
TATTTTAATTAACGATGAATGTTATAGTGAAATTTATGAAGATGCACCGGCTCCTTCGCTTTTAGAAGCTTGCATGCTTA
TTAATAATAAAGATTTTAAAAATGTTTTGGTGATCCATTCGCTCTCCAAACGCTCTAGTGCTCCAGGGCTTAGGAGTGGT
TTTATCGCTGGGGATAGCCGTATTTTAGAAAAATACAAAGCCTTTCGCACTTATTTAGGCTATACGAGCGCTAATGCGAT
TCAAAAGGCGAGCGAAATCGCTTGGCTAGATGAAGAGCATGCGGCATTTTTCCGTAATATTTATGCGAATAATCTCAAAC
TAGCACGAAAAATCTTTAAAGACACGCTCATTTATCCTTATAGTTTTTATGTGTATCTACCTGTTAAAAATGGCGAAAAT
TTTGCAAAAAAACTTTTTGAAAACGAAGGCATTACCACTTTACCGGCTTTGTATTTAGGGCGTAACAACATCGGCACTGA
CTATGCGCGTTTAGCCCTTGTCTATGACACCCCTCTTTTAGAAAAACCTTTAGAAATCATAGAAACTTACCGAGAAAATC
ATGCTTGA

Upstream 100 bases:

>100_bases
TTTATACTCTCTTATACTCTTTTTAGTTCTTTCAGCAATAAACGAAACGCTTAAATTTTAGGTAAGATTAACTATTCCAT
TTTAAGATTAAGGTAGCCCT

Downstream 100 bases:

>100_bases
AATCCCAAAAGTTTTACTAAAAAATTTGCAAGATTGTAAGATCCATTTCATTGGCATAGGGGGGATTGGTATTTCAGGCT
TAGCCAAATACCTTAAAGCT

Product: hypothetical protein

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTFEPYPFERLRALFKEITPKKKGLDLSIGEPRFETPKFIQDALKQHANSLNIYPKSTFEESLRAAQRDFFKRRFKIELK
ENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAQFARAKSLLMPLVKENDFTPILNEKELQEVDLVILN
SPNNPTGRTLSLEELHAWVRLALKYDFILINDECYSEIYEDAPAPSLLEACMLINNKDFKNVLVIHSLSKRSSAPGLRSG
FIAGDSRILEKYKAFRTYLGYTSANAIQKASEIAWLDEEHAAFFRNIYANNLKLARKIFKDTLIYPYSFYVYLPVKNGEN
FAKKLFENEGITTLPALYLGRNNIGTDYARLALVYDTPLLEKPLEIIETYRENHA

Sequences:

>Translated_375_residues
MTFEPYPFERLRALFKEITPKKKGLDLSIGEPRFETPKFIQDALKQHANSLNIYPKSTFEESLRAAQRDFFKRRFKIELK
ENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAQFARAKSLLMPLVKENDFTPILNEKELQEVDLVILN
SPNNPTGRTLSLEELHAWVRLALKYDFILINDECYSEIYEDAPAPSLLEACMLINNKDFKNVLVIHSLSKRSSAPGLRSG
FIAGDSRILEKYKAFRTYLGYTSANAIQKASEIAWLDEEHAAFFRNIYANNLKLARKIFKDTLIYPYSFYVYLPVKNGEN
FAKKLFENEGITTLPALYLGRNNIGTDYARLALVYDTPLLEKPLEIIETYRENHA
>Mature_374_residues
TFEPYPFERLRALFKEITPKKKGLDLSIGEPRFETPKFIQDALKQHANSLNIYPKSTFEESLRAAQRDFFKRRFKIELKE
NELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAQFARAKSLLMPLVKENDFTPILNEKELQEVDLVILNS
PNNPTGRTLSLEELHAWVRLALKYDFILINDECYSEIYEDAPAPSLLEACMLINNKDFKNVLVIHSLSKRSSAPGLRSGF
IAGDSRILEKYKAFRTYLGYTSANAIQKASEIAWLDEEHAAFFRNIYANNLKLARKIFKDTLIYPYSFYVYLPVKNGENF
AKKLFENEGITTLPALYLGRNNIGTDYARLALVYDTPLLEKPLEIIETYRENHA

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=288, Percent_Identity=25.3472222222222, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI56713254, Length=288, Percent_Identity=25.3472222222222, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1788722, Length=364, Percent_Identity=27.4725274725275, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43359; Mature: 43228

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFEPYPFERLRALFKEITPKKKGLDLSIGEPRFETPKFIQDALKQHANSLNIYPKSTFE
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCHHHH
ESLRAAQRDFFKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIY
HHHHHHHHHHHHHHHEEEECHHHHHHHCCCCCEEEECCCEEEEECCCCEEECCCHHHHHH
EGAAQFARAKSLLMPLVKENDFTPILNEKELQEVDLVILNSPNNPTGRTLSLEELHAWVR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCEEEEEEEECCCCCCCCEEEHHHHHHHHH
LALKYDFILINDECYSEIYEDAPAPSLLEACMLINNKDFKNVLVIHSLSKRSSAPGLRSG
HHHHEEEEEECHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECHHCCCCCCCCCC
FIAGDSRILEKYKAFRTYLGYTSANAIQKASEIAWLDEEHAAFFRNIYANNLKLARKIFK
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DTLIYPYSFYVYLPVKNGENFAKKLFENEGITTLPALYLGRNNIGTDYARLALVYDTPLL
HHEECCEEEEEEEEECCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHEEEEEECCCHH
EKPLEIIETYRENHA
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFEPYPFERLRALFKEITPKKKGLDLSIGEPRFETPKFIQDALKQHANSLNIYPKSTFE
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCHHHH
ESLRAAQRDFFKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIY
HHHHHHHHHHHHHHHEEEECHHHHHHHCCCCCEEEECCCEEEEECCCCEEECCCHHHHHH
EGAAQFARAKSLLMPLVKENDFTPILNEKELQEVDLVILNSPNNPTGRTLSLEELHAWVR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCEEEEEEEECCCCCCCCEEEHHHHHHHHH
LALKYDFILINDECYSEIYEDAPAPSLLEACMLINNKDFKNVLVIHSLSKRSSAPGLRSG
HHHHEEEEEECHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECHHCCCCCCCCCC
FIAGDSRILEKYKAFRTYLGYTSANAIQKASEIAWLDEEHAAFFRNIYANNLKLARKIFK
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DTLIYPYSFYVYLPVKNGENFAKKLFENEGITTLPALYLGRNNIGTDYARLALVYDTPLL
HHEECCEEEEEEEEECCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHEEEEEECCCHH
EKPLEIIETYRENHA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA