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The map label for this gene is glk

Identifier: 109947041

GI number: 109947041

Start: 382630

End: 383640

Strand: Reverse

Name: glk

Synonym: Hac_0439

Alternate gene names: 109947041

Gene position: 383640-382630 (Counterclockwise)

Preceding gene: 109947042

Following gene: 109947040

Centisome position: 24.69

GC content: 44.41

Gene sequence:

>1011_bases
ATGCCAAAAACTGAAACTTACCCAAGACTATTAGCCGATATTGGCGGCACAAATGCACGCTTTGGTTTGGAAGTCGCCTC
ACGACAAATTGAATGCATTGAAGTCTTGCGATGCGAAGATTTTGAAAGCTTGAGCGATGCGGTGCGTTTTTATCTTTCTA
AACACCAAGAAAGCCTTAAATTATGCCCTATTTATGGCTCTTTTGCTGTGGCTACGCCCATTATGGGGGATTTTGTCCAA
ATGACAAACAACCACTGGACTTTTTCTATTGAAACGACACGGCAATGTTTGGGATTAGAGAGATTGCTTGTCGTCAATGA
TTTTGTCGCGCAAGCCTTTGCCATCAGCACGATGCAAGAAAATGATCTGGCTCAAGTAGGCGGAATCAAGTGCGAAATTA
ACGCCCCTAAAGCGGTTTTAGGGCCAGGAACTGGGCTTGGGGTAAGCACTCTTATTCAAAATAGCGATGGTTCTTTGAAA
GTCTTACCCGGTGAAGGAGGGCATGTGAGCTTTGCCCCTTTTGATGATTTGGAAATTTTAGTGTGGCAATACGCCCGCTC
TAAATTCAATCATGTGAGCGCAGAAAGGTTTTTGAGTGGGAGCGGCTTGGTGTTGATTTATGAAGCCCTATCTAAACGAA
AAAGCATGGAAAAGGTGGCTAAATTGAGCAAGGCTGAATTGACCCCACAAATCATTAGCGAACGTGCTTTGAATGGGGAT
TACCCTTTGTGCAGATTGACTTTGGATACTTTTTGCTCCATGCTTGGCACACTCGCTGCTGATGTGGCTCTCACTTTGGG
TGCTAGAGGTGGGGTGTATTTGTGTGGGGGGATTATCCCACGATTTATTGACTATTTTAAAACCTCGCCTTTTAGAGCGC
GTTTTGAGACAAAAGGGCGCATGGGAGCGTTTCTCGCTTCTATCCCTGTGCATGTCGTGTTGAAAAAAACTCCAGGACTT
GACGGAGTAGGCATTGCGTTAGAGAATTATTTACTGCATGATAAAATATAG

Upstream 100 bases:

>100_bases
AAAAGGGGAGTTTTAGAAAAGGCTTTAAAAGAAAACGCCCCTTATTCTCTACCAATTGCTCGGATTTTACACTCTAAAAA
AGTTACCACGGAGGTTTTTT

Downstream 100 bases:

>100_bases
TGCCGTTCAAATGGAAGCGATTAAAAAGCGTTTTTAAAACCAGTGCAATAACGCAAGCTCTGTGTTTGATTTGGTTTTAT
TTCAATAGTGCATTGATCAT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPKTETYPRLLADIGGTNARFGLEVASRQIECIEVLRCEDFESLSDAVRFYLSKHQESLKLCPIYGSFAVATPIMGDFVQ
MTNNHWTFSIETTRQCLGLERLLVVNDFVAQAFAISTMQENDLAQVGGIKCEINAPKAVLGPGTGLGVSTLIQNSDGSLK
VLPGEGGHVSFAPFDDLEILVWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKSMEKVAKLSKAELTPQIISERALNGD
YPLCRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGRMGAFLASIPVHVVLKKTPGL
DGVGIALENYLLHDKI

Sequences:

>Translated_336_residues
MPKTETYPRLLADIGGTNARFGLEVASRQIECIEVLRCEDFESLSDAVRFYLSKHQESLKLCPIYGSFAVATPIMGDFVQ
MTNNHWTFSIETTRQCLGLERLLVVNDFVAQAFAISTMQENDLAQVGGIKCEINAPKAVLGPGTGLGVSTLIQNSDGSLK
VLPGEGGHVSFAPFDDLEILVWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKSMEKVAKLSKAELTPQIISERALNGD
YPLCRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGRMGAFLASIPVHVVLKKTPGL
DGVGIALENYLLHDKI
>Mature_335_residues
PKTETYPRLLADIGGTNARFGLEVASRQIECIEVLRCEDFESLSDAVRFYLSKHQESLKLCPIYGSFAVATPIMGDFVQM
TNNHWTFSIETTRQCLGLERLLVVNDFVAQAFAISTMQENDLAQVGGIKCEINAPKAVLGPGTGLGVSTLIQNSDGSLKV
LPGEGGHVSFAPFDDLEILVWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKSMEKVAKLSKAELTPQIISERALNGDY
PLCRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGRMGAFLASIPVHVVLKKTPGLD
GVGIALENYLLHDKI

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=325, Percent_Identity=42.1538461538462, Blast_Score=246, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_HELAH (Q17YK6)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664269.1
- STRING:   Q17YK6
- GeneID:   4177766
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0439
- NMPDR:   fig|382638.8.peg.428
- eggNOG:   COG0837
- HOGENOM:   HBG644410
- OMA:   VDIGGTH
- PhylomeDB:   Q17YK6
- ProtClustDB:   PRK00292
- BioCyc:   HACI382638:HAC_0439-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 36737; Mature: 36606

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTETYPRLLADIGGTNARFGLEVASRQIECIEVLRCEDFESLSDAVRFYLSKHQESLK
CCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCE
LCPIYGSFAVATPIMGDFVQMTNNHWTFSIETTRQCLGLERLLVVNDFVAQAFAISTMQE
EEEEECCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
NDLAQVGGIKCEINAPKAVLGPGTGLGVSTLIQNSDGSLKVLPGEGGHVSFAPFDDLEIL
CCHHHHCCEEEEECCCCEEECCCCCCCHHHHEECCCCCEEEECCCCCEEEECCCCCHHHH
VWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKSMEKVAKLSKAELTPQIISERALNGD
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
YPLCRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGR
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCEECCCCCC
MGAFLASIPVHVVLKKTPGLDGVGIALENYLLHDKI
HHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PKTETYPRLLADIGGTNARFGLEVASRQIECIEVLRCEDFESLSDAVRFYLSKHQESLK
CCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCE
LCPIYGSFAVATPIMGDFVQMTNNHWTFSIETTRQCLGLERLLVVNDFVAQAFAISTMQE
EEEEECCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
NDLAQVGGIKCEINAPKAVLGPGTGLGVSTLIQNSDGSLKVLPGEGGHVSFAPFDDLEIL
CCHHHHCCEEEEECCCCEEECCCCCCCHHHHEECCCCCEEEECCCCCEEEECCCCCHHHH
VWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKSMEKVAKLSKAELTPQIISERALNGD
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
YPLCRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGR
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCEECCCCCC
MGAFLASIPVHVVLKKTPGLDGVGIALENYLLHDKI
HHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA