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The map label for this gene is pgl [H]

Identifier: 109947042

GI number: 109947042

Start: 383627

End: 384310

Strand: Reverse

Name: pgl [H]

Synonym: Hac_0440

Alternate gene names: 109947042

Gene position: 384310-383627 (Counterclockwise)

Preceding gene: 109947043

Following gene: 109947041

Centisome position: 24.73

GC content: 36.11

Gene sequence:

>684_bases
ATGGGTTATCAATTATTTGAATTTGAAAGTTTAGAAGATTGTAATAAGGCTTTAATAGAGCATTTTAAAGAATTTTTTAA
CGCTACCTTAAAAAAGCATCATCAAGTTTCTATTGCTTTTTCTGGAGGCCGTTCGCCCATTAGCTTGTTGCAAAAATTGA
GCGTTTTAGATCTCAAGTGGCATGAATGTGTAGTCAGTTTAGTAGATGAACGCATTATAGATACAAGCCATAAGGATAGT
AATACCAAGTTATTACACGATTATTTGTTGCAAAATAACGCCCTAAAAGCTTCTTTCATTCCGCTTTTACCCAAAGAGAT
TTCTTGCAATCAAAACGCGCTTTTAAATTTTGCTAACCAGCACTTCAAACAGCCACATTTAGCCATTCTAGGCATGGGGA
CAGATGGGCATACGGCTAGCCTTTTTCCTGAAACGAGCACTTTTTTAAACGAAGAAAAAGAAAATATCGTCTTAACTAAG
CCAGCTAACGCTCCTTATGAACGCCTGAGCATGTCTATTAACGCCTTAGAAAATTGCGAAAAACTTTTTTTAAGCATTAG
TGGAGCGGAAAAAAGGGGAGTTTTAGAAAAGGCTTTAAAAGAAAACGCCCCTTATTCTCTACCAATTGCTCGGATTTTAC
ACTCTAAAAAAGTTACCACGGAGGTTTTTTATGCCAAAAACTGA

Upstream 100 bases:

>100_bases
GAGGGTTTTATCAATAACGCCACGCCCTTACATTTCTATGAAAGCCACAACCTAAACGAGTTAGAATTTTTAAAACCACT
CTATCAATAAAAGGAATTTC

Downstream 100 bases:

>100_bases
AACTTACCCAAGACTATTAGCCGATATTGGCGGCACAAATGCACGCTTTGGTTTGGAAGTCGCCTCACGACAAATTGAAT
GCATTGAAGTCTTGCGATGC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MGYQLFEFESLEDCNKALIEHFKEFFNATLKKHHQVSIAFSGGRSPISLLQKLSVLDLKWHECVVSLVDERIIDTSHKDS
NTKLLHDYLLQNNALKASFIPLLPKEISCNQNALLNFANQHFKQPHLAILGMGTDGHTASLFPETSTFLNEEKENIVLTK
PANAPYERLSMSINALENCEKLFLSISGAEKRGVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN

Sequences:

>Translated_227_residues
MGYQLFEFESLEDCNKALIEHFKEFFNATLKKHHQVSIAFSGGRSPISLLQKLSVLDLKWHECVVSLVDERIIDTSHKDS
NTKLLHDYLLQNNALKASFIPLLPKEISCNQNALLNFANQHFKQPHLAILGMGTDGHTASLFPETSTFLNEEKENIVLTK
PANAPYERLSMSINALENCEKLFLSISGAEKRGVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN
>Mature_226_residues
GYQLFEFESLEDCNKALIEHFKEFFNATLKKHHQVSIAFSGGRSPISLLQKLSVLDLKWHECVVSLVDERIIDTSHKDSN
TKLLHDYLLQNNALKASFIPLLPKEISCNQNALLNFANQHFKQPHLAILGMGTDGHTASLFPETSTFLNEEKENIVLTKP
ANAPYERLSMSINALENCEKLFLSISGAEKRGVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=206, Percent_Identity=31.5533980582524, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25626; Mature: 25495

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYQLFEFESLEDCNKALIEHFKEFFNATLKKHHQVSIAFSGGRSPISLLQKLSVLDLKW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHH
HECVVSLVDERIIDTSHKDSNTKLLHDYLLQNNALKASFIPLLPKEISCNQNALLNFANQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHHH
HFKQPHLAILGMGTDGHTASLFPETSTFLNEEKENIVLTKPANAPYERLSMSINALENCE
HCCCCCEEEEEECCCCCCEECCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
KLFLSISGAEKRGVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN
HHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
GYQLFEFESLEDCNKALIEHFKEFFNATLKKHHQVSIAFSGGRSPISLLQKLSVLDLKW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHH
HECVVSLVDERIIDTSHKDSNTKLLHDYLLQNNALKASFIPLLPKEISCNQNALLNFANQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHHH
HFKQPHLAILGMGTDGHTASLFPETSTFLNEEKENIVLTKPANAPYERLSMSINALENCE
HCCCCCEEEEEECCCCCCEECCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
KLFLSISGAEKRGVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN
HHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]