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The map label for this gene is nupC [C]

Identifier: 109947005

GI number: 109947005

Start: 342832

End: 344088

Strand: Direct

Name: nupC [C]

Synonym: Hac_0398

Alternate gene names: 109947005

Gene position: 342832-344088 (Clockwise)

Preceding gene: 109947002

Following gene: 109947006

Centisome position: 22.06

GC content: 43.28

Gene sequence:

>1257_bases
ATGATTTCTAGCTCTCTTTTTAGTGTTGTAGGGATGGCGGTGCTTTTTCTTATTGCTTGGGTTTTTTCTGGCGATAAAAG
GGCTATTAATTATCGCACGATTATCAGTGCGTTTGTAATCCAGGTGGTTTTAGGGGCGTTTGCTTTGTATGTGCCTTTAG
GCAGAGAAATGCTACAAGGTTTAGCGGGTGGCATACAAAGCGTGATTAGTTACGGCTATGAGGGGGTGCGCTTCTTGTTT
GGCAATCTCGCTCCAAACGCTAAAGGCGATCAAGGGATAGGTGGGTTTATTTTTGCGATCAATGTTTTAGCGATAATCAT
CTTTTTTGCCAGCTTGATTTCGCTTTTATATTATTTAAAAATCATGCCTTTAGTGATCAATCTTATCGGTGGGGCGTTGC
GAAAATGTTTAGGCACTTCTAAAGCAGAAAGCATGAGTGCAGCGGCTAATATTTTTGTCGCGCACACCGAAGCGCCCCTA
GTCATTAAACCTTATTTGAAAAGCATGAGTGATTCAGAGATTTTTGCGGTCATGTGCGTGGGTATGGCGAGCGTTGCAGG
GCCTGTGTTGGCTGGGTATGCGAGCATGGGTATTCCTTTGCCTTATTTGATCGCTGCATCGTTTATGTCCGCTCCTGGGG
GTTTGTTGTTCGCTAAAATCATCTACCCACAAAGCGAAAAAATTTCTAACCATGCAGATATTTCTGTGGAAAAGCATGTC
AATGTTATAGAAGCTATCGCTAATGGGGCAAGCACAGGGCTTCATTTGGCTTTGCATGTGGGGGCGATGCTTTTAGCTTT
TGTGGGGATGCTTGCACTCATTAATGGGCTTTTAGGGGTTATAGGGGGATTTTTGGGCATGGAGCATTTGTCTTTAGGGG
TGGTTTTAGGCACGCTTTTAAAACCTTTAGCCTTTATGTTAGGCATTCCTTGGAGTCAAGCTGGGATTGCCGGAGAAATC
ATAGGCATTAAAATCGCTCTCAATGAATTTGTGGGCTATATGCAATTATTGCCTTATTTGGGCGATAACCCTCCTTTAAT
CTTGAGCGAGAAAACTAAAGCCATCATCACTTTTGCGTTGTGTGGGTTTGCTAATTTAAGTTCAGTCGCTATGCTTATTG
GAGGGCTTGGTAGTTTAGTGCCTAAAAAGAAAGATTTCATTGCAAGACTCGCTTTAAGAGCGGTGCTTGCAGGCACTCTT
TCTAATTTCATGAGCGCGACTATCGCTGGGCTATTCATAGAGCTAAACAGCCATTAA

Upstream 100 bases:

>100_bases
TGATTTAATTTTCGTTTAAACTCCATTTAATCTTTTTTTTAGAAAATCTAAACTACAATAGTAGTGTTGCATCTTTTAAA
TTTCTTATAGGGATTTGACG

Downstream 100 bases:

>100_bases
AAGGACAAGACATGCAAAAAAGAGTGGTGGTTTTATTACTAGATTCTTTTGGTATAGGGGCTAGTGAAGACGCTAAAGAT
TTTGGCGATTTGGGGGCGAA

Product: pyrimidine nucleoside transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MISSSLFSVVGMAVLFLIAWVFSGDKRAINYRTIISAFVIQVVLGAFALYVPLGREMLQGLAGGIQSVISYGYEGVRFLF
GNLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLKIMPLVINLIGGALRKCLGTSKAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQSEKISNHADISVEKHV
NVIEAIANGASTGLHLALHVGAMLLAFVGMLALINGLLGVIGGFLGMEHLSLGVVLGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDFIARLALRAVLAGTL
SNFMSATIAGLFIELNSH

Sequences:

>Translated_418_residues
MISSSLFSVVGMAVLFLIAWVFSGDKRAINYRTIISAFVIQVVLGAFALYVPLGREMLQGLAGGIQSVISYGYEGVRFLF
GNLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLKIMPLVINLIGGALRKCLGTSKAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQSEKISNHADISVEKHV
NVIEAIANGASTGLHLALHVGAMLLAFVGMLALINGLLGVIGGFLGMEHLSLGVVLGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDFIARLALRAVLAGTL
SNFMSATIAGLFIELNSH
>Mature_418_residues
MISSSLFSVVGMAVLFLIAWVFSGDKRAINYRTIISAFVIQVVLGAFALYVPLGREMLQGLAGGIQSVISYGYEGVRFLF
GNLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLKIMPLVINLIGGALRKCLGTSKAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQSEKISNHADISVEKHV
NVIEAIANGASTGLHLALHVGAMLLAFVGMLALINGLLGVIGGFLGMEHLSLGVVLGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDFIARLALRAVLAGTL
SNFMSATIAGLFIELNSH

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI227116277, Length=415, Percent_Identity=35.6626506024096, Blast_Score=261, Evalue=9e-70,
Organism=Homo sapiens, GI42542381, Length=423, Percent_Identity=34.51536643026, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI11545853, Length=379, Percent_Identity=34.3007915567282, Blast_Score=235, Evalue=5e-62,
Organism=Escherichia coli, GI1788485, Length=412, Percent_Identity=44.6601941747573, Blast_Score=324, Evalue=6e-90,
Organism=Escherichia coli, GI1788488, Length=412, Percent_Identity=45.1456310679612, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI1788737, Length=405, Percent_Identity=27.9012345679012, Blast_Score=160, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71991794, Length=404, Percent_Identity=31.1881188118812, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17560276, Length=399, Percent_Identity=31.8295739348371, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI25146537, Length=226, Percent_Identity=30.0884955752212, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45552517, Length=419, Percent_Identity=34.3675417661098, Blast_Score=257, Evalue=9e-69,
Organism=Drosophila melanogaster, GI45552519, Length=419, Percent_Identity=34.3675417661098, Blast_Score=257, Evalue=9e-69,
Organism=Drosophila melanogaster, GI19921868, Length=419, Percent_Identity=34.3675417661098, Blast_Score=257, Evalue=9e-69,
Organism=Drosophila melanogaster, GI281360430, Length=366, Percent_Identity=34.4262295081967, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43889; Mature: 43889

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSSLFSVVGMAVLFLIAWVFSGDKRAINYRTIISAFVIQVVLGAFALYVPLGREMLQG
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGGIQSVISYGYEGVRFLFGNLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLK
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMPLVINLIGGALRKCLGTSKAESMSAAANIFVAHTEAPLVIKPYLKSMSDSEIFAVMCV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEEHHHHHCCCCCHHHHHHHH
GMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQSEKISNHADISVEKHV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEHHEECCCHHHCCCCCCCCHHHHH
NVIEAIANGASTGLHLALHVGAMLLAFVGMLALINGLLGVIGGFLGMEHLSLGVVLGTLL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLAFMLGIPWSQAGIAGEIIGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFAL
HHHHHHHCCCCCCCCCCEEHEEHEEHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
CGFANLSSVAMLIGGLGSLVPKKKDFIARLALRAVLAGTLSNFMSATIAGLFIELNSH
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MISSSLFSVVGMAVLFLIAWVFSGDKRAINYRTIISAFVIQVVLGAFALYVPLGREMLQG
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGGIQSVISYGYEGVRFLFGNLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLK
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMPLVINLIGGALRKCLGTSKAESMSAAANIFVAHTEAPLVIKPYLKSMSDSEIFAVMCV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEEHHHHHCCCCCHHHHHHHH
GMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQSEKISNHADISVEKHV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEHHEECCCHHHCCCCCCCCHHHHH
NVIEAIANGASTGLHLALHVGAMLLAFVGMLALINGLLGVIGGFLGMEHLSLGVVLGTLL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLAFMLGIPWSQAGIAGEIIGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFAL
HHHHHHHCCCCCCCCCCEEHEEHEEHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
CGFANLSSVAMLIGGLGSLVPKKKDFIARLALRAVLAGTLSNFMSATIAGLFIELNSH
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]