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The map label for this gene is sdaC [H]

Identifier: 109946926

GI number: 109946926

Start: 266291

End: 267532

Strand: Reverse

Name: sdaC [H]

Synonym: Hac_0313

Alternate gene names: 109946926

Gene position: 267532-266291 (Counterclockwise)

Preceding gene: 109946928

Following gene: 109946925

Centisome position: 17.22

GC content: 37.12

Gene sequence:

>1242_bases
ATGACGCAAAAAAAAGAAACTCCAAAAGATCTCAAAAAACTCAATTTGTTTGATTTGCGCTGGATGGCGTCCTTATTTGG
CACGGCGGTGGGGGCTGGGATTTTATTTTTGCCTATTAGAGCCGGTGGGCATGGGATATGGGCCATTGTAGCGATGAGTG
CAATTATTTTCCCTTTAACTTACCTAGGGCATAGAGCTTTAGCTTATTTTATAGGATCTAAAGATAAAGAAGACATTACG
ATGGTCGTTCGCTCGCATTTTGGCACTCAATGGGGGTTTCTTATCACTTTGCTTTATTTCTTGGCGATTTATCCTATTTG
CTTGGCTTATGGGGTGGGTATCACGAATGTGTTTGACAATTTTTTTACCAATCAATTGCATTTAGTGCCTTTTCATCGTA
GCTTATTGGCTGTCGTTTTAGTTTCTTTAATGATGCTTGTAATGGTTTTTAACGCCACGATTGTCACACGCATTTGTAAC
GCTTTAGTGTATCCTTTATGCTTGATTTTATTGCTTTTTTCTTTGTATCTTATCCCCTATTGGCAAGTTAATAACCTTTC
TGTAATGCCGAGTTTTAAAGAATTTGTGCTAGCTATTTGGCTAACCTTACCGGTGCTTGTGTTTTCATTCAACCATAGCC
CCATTATTTCAACCTTCACTCAAAATGTGGAAAAAGAATACGGCGCTTTCAAAGAGTATAAACTCAATCAAATTGAATTA
GGCACATCGCTCATGCTTTTAGGGTTTGTGATGTTTTTTGTGTTTTCTTGTGTCATGTGCTTGAATGCTGATGATTTTAT
GAAAGCAAGGGAGCAAAATATCCCCATTTTAAGCTATTTTGCTAACACTTTAAACAACCCCTTAATCAATTATGCAGGGC
CTGTGGTGGCTTTTTTAGCGATTTTTTCATCTTTTTTTGGGCATTATTACGGAGCTAAAGAGGGCTTAGAAGGCATTATT
ATACAAGGCTTAAAATTGAAAAAGGCTTCTAAAACCTTGAGCGTGGGTGTAACGATCTTTTTATGGCTTAGTATCACGCT
TGTGGCTTATATTAACCCTAATATCTTAGATTTTATTGAAAATTTAGGCGGTCCCATTATCGCGCTCATTCTTTTTGTAA
TGCCTATGGTAGCTTTTTATAGCGTTTCTAGTTTGAAGCGTTTTAGAAATTTCAAAGTGGATATTTTTGTGTTTATCTTT
GGGAGCTTAACGGCTTTGAGCGTGTTTTTAGGATTGTTCTAA

Upstream 100 bases:

>100_bases
GTAAATGCACGCTTCAACCTCCCTTTAATTCCAATAAACCCTAATCATAAAAAGCTTTATGATACAATGAAAATTCATAC
GATAAAAGGGTGGTTATGGC

Downstream 100 bases:

>100_bases
TGGCTAGTTTTTCTATTTTATCCATTTTTAAAATCGGCGTTGGGCCTAGCTCTTCACACACCATAGGGCCTATGGAAGCT
GGGGCGAGATTTTGCGGATT

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTQKKETPKDLKKLNLFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVAMSAIIFPLTYLGHRALAYFIGSKDKEDIT
MVVRSHFGTQWGFLITLLYFLAIYPICLAYGVGITNVFDNFFTNQLHLVPFHRSLLAVVLVSLMMLVMVFNATIVTRICN
ALVYPLCLILLLFSLYLIPYWQVNNLSVMPSFKEFVLAIWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIEL
GTSLMLLGFVMFFVFSCVMCLNADDFMKAREQNIPILSYFANTLNNPLINYAGPVVAFLAIFSSFFGHYYGAKEGLEGII
IQGLKLKKASKTLSVGVTIFLWLSITLVAYINPNILDFIENLGGPIIALILFVMPMVAFYSVSSLKRFRNFKVDIFVFIF
GSLTALSVFLGLF

Sequences:

>Translated_413_residues
MTQKKETPKDLKKLNLFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVAMSAIIFPLTYLGHRALAYFIGSKDKEDIT
MVVRSHFGTQWGFLITLLYFLAIYPICLAYGVGITNVFDNFFTNQLHLVPFHRSLLAVVLVSLMMLVMVFNATIVTRICN
ALVYPLCLILLLFSLYLIPYWQVNNLSVMPSFKEFVLAIWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIEL
GTSLMLLGFVMFFVFSCVMCLNADDFMKAREQNIPILSYFANTLNNPLINYAGPVVAFLAIFSSFFGHYYGAKEGLEGII
IQGLKLKKASKTLSVGVTIFLWLSITLVAYINPNILDFIENLGGPIIALILFVMPMVAFYSVSSLKRFRNFKVDIFVFIF
GSLTALSVFLGLF
>Mature_412_residues
TQKKETPKDLKKLNLFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVAMSAIIFPLTYLGHRALAYFIGSKDKEDITM
VVRSHFGTQWGFLITLLYFLAIYPICLAYGVGITNVFDNFFTNQLHLVPFHRSLLAVVLVSLMMLVMVFNATIVTRICNA
LVYPLCLILLLFSLYLIPYWQVNNLSVMPSFKEFVLAIWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIELG
TSLMLLGFVMFFVFSCVMCLNADDFMKAREQNIPILSYFANTLNNPLINYAGPVVAFLAIFSSFFGHYYGAKEGLEGIII
QGLKLKKASKTLSVGVTIFLWLSITLVAYINPNILDFIENLGGPIIALILFVMPMVAFYSVSSLKRFRNFKVDIFVFIFG
SLTALSVFLGLF

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=407, Percent_Identity=42.7518427518428, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1789504, Length=423, Percent_Identity=40.661938534279, Blast_Score=274, Evalue=6e-75,
Organism=Escherichia coli, GI1789211, Length=381, Percent_Identity=36.745406824147, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1789961, Length=412, Percent_Identity=24.7572815533981, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI145693183, Length=423, Percent_Identity=24.822695035461, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 46498; Mature: 46367

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKKETPKDLKKLNLFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVAMSAIIFPLT
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
YLGHRALAYFIGSKDKEDITMVVRSHFGTQWGFLITLLYFLAIYPICLAYGVGITNVFDN
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FFTNQLHLVPFHRSLLAVVLVSLMMLVMVFNATIVTRICNALVYPLCLILLLFSLYLIPY
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WQVNNLSVMPSFKEFVLAIWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIEL
EEECCEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHH
GTSLMLLGFVMFFVFSCVMCLNADDFMKAREQNIPILSYFANTLNNPLINYAGPVVAFLA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
IFSSFFGHYYGAKEGLEGIIIQGLKLKKASKTLSVGVTIFLWLSITLVAYINPNILDFIE
HHHHHHHHHCCHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NLGGPIIALILFVMPMVAFYSVSSLKRFRNFKVDIFVFIFGSLTALSVFLGLF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQKKETPKDLKKLNLFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVAMSAIIFPLT
CCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
YLGHRALAYFIGSKDKEDITMVVRSHFGTQWGFLITLLYFLAIYPICLAYGVGITNVFDN
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FFTNQLHLVPFHRSLLAVVLVSLMMLVMVFNATIVTRICNALVYPLCLILLLFSLYLIPY
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WQVNNLSVMPSFKEFVLAIWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIEL
EEECCEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHH
GTSLMLLGFVMFFVFSCVMCLNADDFMKAREQNIPILSYFANTLNNPLINYAGPVVAFLA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
IFSSFFGHYYGAKEGLEGIIIQGLKLKKASKTLSVGVTIFLWLSITLVAYINPNILDFIE
HHHHHHHHHCCHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NLGGPIIALILFVMPMVAFYSVSSLKRFRNFKVDIFVFIFGSLTALSVFLGLF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]