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The map label for this gene is sdaA [H]

Identifier: 109946925

GI number: 109946925

Start: 264924

End: 266291

Strand: Reverse

Name: sdaA [H]

Synonym: Hac_0312

Alternate gene names: 109946925

Gene position: 266291-264924 (Counterclockwise)

Preceding gene: 109946926

Following gene: 109946920

Centisome position: 17.14

GC content: 40.13

Gene sequence:

>1368_bases
ATGGCTAGTTTTTCTATTTTATCCATTTTTAAAATCGGCGTTGGGCCTAGCTCTTCACACACCATAGGGCCTATGGAAGC
TGGGGCGAGATTTTGCGGATTGTTAAAAGATATTTTAGAACAAGTTGCACGCATTCAAATCACCTTGCATGGCTCATTAG
CATTGACCGGTAAAGGGCATTTGAGCGATGAGGCGGTTTTGATTGGCTTGCATGGTATTTATGCTAACGAGTTGGATATA
GCAACCAAAAAAGCCTTGCTGCATGAAGTGTTTGAAAATAAGGTTTTAAAACTCGCTAACCAACATCATATCCCTTTTGA
TTATTCTAAAGATTTGATTTTTGACAATAAACCTTTAGCAAGACACCAAAATGCTCTTATTTTAAAAGCTTTTAACGCTA
AAAATGAGGTTTTAAAAGAAGAAACCTACTATTCTGTTGGCGGAGGATTTGTCTATACTGAAAAAGAATTAGACAACTTG
GCTGAAGAGAATGAAAATGAAAGCGTCGCTTATGATTTTTCAAGCGCTAAAGAATTGCTAGAATTATGCCAAAAACACGA
AAAAAACATTGCTGAAATCGTGCGTTTGAGAGAAAACGCACTCAAAAACCACCCTGATACAACGATGACTAAAATTTATC
ATGCGATGCTTGAATGCTATCATAATGGGGCTAACTCTAAAGAAATGTATCTTCCTGGTTTTTTGAAAGTAACACGATTA
GCCCCAAGCATTAAAACGCGTTTAGAAAAACACCCCAAAAATGGGAATGACCCCTTAGCTTTGATTGATTACATCTCGCT
TTACGCTCGTGCCATTGCTGAAGAAAATGCTAGTGGCGGTAAGGTGGTAACCGCCCCTACTAATGGAGCGTGCGCGGTGG
TGCCAAGCGTACTTTTATATGCTAAAAACCATTTGTTTGAAAATTTATCGCAAAAATCTATCAATGATTTTTTGCTCACT
AGTGCGGCGATTGGCTATCTTTATAAGAAAAACGCTTCCTTGAGTGGTGCAGAAGCGGGGTGTCAGGCTGAAATTGGTGT
GGCAAGCTCTATGGCTGCAGGGGGGTTAGCCTATTTGTATCAAGCCACGATCAAACAGGTTTTAATGGCTAGTGAAATCG
CTATGGAACACCACTTGGGATTGACATGCGATCCTGTTGGAGGCTTGGTGCAAATCCCTTGCATTGAACGCAATGTTTTA
GGGGCAATTAAAGCGATCAGCGCTTCTAAATTGGCTTTAGAAGATGCATACAAGCCTAAAGTGAGTTTAGATGAAGTGAT
CGCTACGATGTATGCGACCGGAAAAGACATGAATGAAAAATACAAAGAGACTTCGTTAGGGGGATTAGCCAAGACGCTAG
AATGCTAA

Upstream 100 bases:

>100_bases
GCGTTTCTAGTTTGAAGCGTTTTAGAAATTTCAAAGTGGATATTTTTGTGTTTATCTTTGGGAGCTTAACGGCTTTGAGC
GTGTTTTTAGGATTGTTCTA

Downstream 100 bases:

>100_bases
AATAGGGTTTTAAGAGTTTATCATAAAATGGAATTTAAAAACCCCATTTTTGAAAAAAAATGAAAGTCAGTATTTGATTA
AAACCCTACAAAGACCAATA

Product: hypothetical protein

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MASFSILSIFKIGVGPSSSHTIGPMEAGARFCGLLKDILEQVARIQITLHGSLALTGKGHLSDEAVLIGLHGIYANELDI
ATKKALLHEVFENKVLKLANQHHIPFDYSKDLIFDNKPLARHQNALILKAFNAKNEVLKEETYYSVGGGFVYTEKELDNL
AEENENESVAYDFSSAKELLELCQKHEKNIAEIVRLRENALKNHPDTTMTKIYHAMLECYHNGANSKEMYLPGFLKVTRL
APSIKTRLEKHPKNGNDPLALIDYISLYARAIAEENASGGKVVTAPTNGACAVVPSVLLYAKNHLFENLSQKSINDFLLT
SAAIGYLYKKNASLSGAEAGCQAEIGVASSMAAGGLAYLYQATIKQVLMASEIAMEHHLGLTCDPVGGLVQIPCIERNVL
GAIKAISASKLALEDAYKPKVSLDEVIATMYATGKDMNEKYKETSLGGLAKTLEC

Sequences:

>Translated_455_residues
MASFSILSIFKIGVGPSSSHTIGPMEAGARFCGLLKDILEQVARIQITLHGSLALTGKGHLSDEAVLIGLHGIYANELDI
ATKKALLHEVFENKVLKLANQHHIPFDYSKDLIFDNKPLARHQNALILKAFNAKNEVLKEETYYSVGGGFVYTEKELDNL
AEENENESVAYDFSSAKELLELCQKHEKNIAEIVRLRENALKNHPDTTMTKIYHAMLECYHNGANSKEMYLPGFLKVTRL
APSIKTRLEKHPKNGNDPLALIDYISLYARAIAEENASGGKVVTAPTNGACAVVPSVLLYAKNHLFENLSQKSINDFLLT
SAAIGYLYKKNASLSGAEAGCQAEIGVASSMAAGGLAYLYQATIKQVLMASEIAMEHHLGLTCDPVGGLVQIPCIERNVL
GAIKAISASKLALEDAYKPKVSLDEVIATMYATGKDMNEKYKETSLGGLAKTLEC
>Mature_454_residues
ASFSILSIFKIGVGPSSSHTIGPMEAGARFCGLLKDILEQVARIQITLHGSLALTGKGHLSDEAVLIGLHGIYANELDIA
TKKALLHEVFENKVLKLANQHHIPFDYSKDLIFDNKPLARHQNALILKAFNAKNEVLKEETYYSVGGGFVYTEKELDNLA
EENENESVAYDFSSAKELLELCQKHEKNIAEIVRLRENALKNHPDTTMTKIYHAMLECYHNGANSKEMYLPGFLKVTRLA
PSIKTRLEKHPKNGNDPLALIDYISLYARAIAEENASGGKVVTAPTNGACAVVPSVLLYAKNHLFENLSQKSINDFLLTS
AAIGYLYKKNASLSGAEAGCQAEIGVASSMAAGGLAYLYQATIKQVLMASEIAMEHHLGLTCDPVGGLVQIPCIERNVLG
AIKAISASKLALEDAYKPKVSLDEVIATMYATGKDMNEKYKETSLGGLAKTLEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=458, Percent_Identity=45.8515283842795, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=47.0459518599562, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1789161, Length=458, Percent_Identity=44.9781659388646, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49516; Mature: 49384

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFSILSIFKIGVGPSSSHTIGPMEAGARFCGLLKDILEQVARIQITLHGSLALTGKGH
CCCCCEEHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECEEEEECCCC
LSDEAVLIGLHGIYANELDIATKKALLHEVFENKVLKLANQHHIPFDYSKDLIFDNKPLA
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCH
RHQNALILKAFNAKNEVLKEETYYSVGGGFVYTEKELDNLAEENENESVAYDFSSAKELL
HCCCEEEEEEECCHHHHHHHHCEEECCCCEEEEHHHHHHHHHCCCCCEEEECHHHHHHHH
ELCQKHEKNIAEIVRLRENALKNHPDTTMTKIYHAMLECYHNGANSKEMYLPGFLKVTRL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHH
APSIKTRLEKHPKNGNDPLALIDYISLYARAIAEENASGGKVVTAPTNGACAVVPSVLLY
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHH
AKNHLFENLSQKSINDFLLTSAAIGYLYKKNASLSGAEAGCQAEIGVASSMAAGGLAYLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHH
QATIKQVLMASEIAMEHHLGLTCDPVGGLVQIPCIERNVLGAIKAISASKLALEDAYKPK
HHHHHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC
VSLDEVIATMYATGKDMNEKYKETSLGGLAKTLEC
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASFSILSIFKIGVGPSSSHTIGPMEAGARFCGLLKDILEQVARIQITLHGSLALTGKGH
CCCCEEHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECEEEEECCCC
LSDEAVLIGLHGIYANELDIATKKALLHEVFENKVLKLANQHHIPFDYSKDLIFDNKPLA
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCH
RHQNALILKAFNAKNEVLKEETYYSVGGGFVYTEKELDNLAEENENESVAYDFSSAKELL
HCCCEEEEEEECCHHHHHHHHCEEECCCCEEEEHHHHHHHHHCCCCCEEEECHHHHHHHH
ELCQKHEKNIAEIVRLRENALKNHPDTTMTKIYHAMLECYHNGANSKEMYLPGFLKVTRL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHH
APSIKTRLEKHPKNGNDPLALIDYISLYARAIAEENASGGKVVTAPTNGACAVVPSVLLY
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHH
AKNHLFENLSQKSINDFLLTSAAIGYLYKKNASLSGAEAGCQAEIGVASSMAAGGLAYLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHH
QATIKQVLMASEIAMEHHLGLTCDPVGGLVQIPCIERNVLGAIKAISASKLALEDAYKPK
HHHHHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC
VSLDEVIATMYATGKDMNEKYKETSLGGLAKTLEC
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]