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The map label for this gene is tsf

Identifier: 109946899

GI number: 109946899

Start: 236361

End: 237428

Strand: Reverse

Name: tsf

Synonym: Hac_0285

Alternate gene names: 109946899

Gene position: 237428-236361 (Counterclockwise)

Preceding gene: 109946900

Following gene: 109946898

Centisome position: 15.28

GC content: 39.33

Gene sequence:

>1068_bases
ATGTCAGAAATTAGTGCTCAATTAGTCAAAAAGCTGAGAGACTTAACCGATGTGGGCATGATGGATTGCAAAAAAGCCCT
TGTGGAAGTGGCTGGGGATTTGCAAAAGGCTATTGATTTCTTGCGCGAAAAGGGCTTGAGCAAAGCCGCTAAAAAAGCCG
ATAGGATCGCTTCTGAGGGCGTGGTCGCTTTAGAAGTCGCACCTGATTTTAAAAGTGCAGTGATGGTAGAAATCAATAGT
GAAACGGATTTTGTGGCTAAAAATGAGGGCTTTAAGGAATTGGTTAAAAAAACTTTAGAAACGATCAAAGTCCACAACGC
CCATACAAGAGAAGAGTTGCTTAAAAGCTCGTTAGACAACAAGCCTTTTGAAGAATATTTACACTCTCAAATCGCTGTGA
TTGGTGAGAACATTTTAGTGAGGAAAATCGCTAATTCTAAAGCCCCTAGCTCTCACATCATCAATGGTTATGCACATTCT
AATGCTAGAGTGGGCGTGCTAATCACCATGAAATACAATAATGAAAAAAACGCTCCAAAAGCGGTTGAACTAGCTAGAAA
TATCGCTATGCATGCCGCAGCGATGAAACCTCAAGTGCTAGATTGCAAAGACTTTAGCCTTGATTTTGTCAAAAAAGAAA
CTTTAGTATTGATCGCTGAAATTGAAAAAGACAATGAAGAAGCCAAACGATTGGGCAAACCTTTGAAAAACATTCCTACT
TTTGGGAGTCGCATTGAATTGAGCGATGAAGTTTTAGCCCATCAAAAGAAAGTCTTTGAAGACGAATTGAAAGAGCAAGG
CAAACCTGAAAAAATTTGGGATAAAATCGTTCTAGGGAAAATGGAAAGATTTATCGCTGACAACACCCTTATTGATCAAC
GCCTAACCCTTTTAGGGCAATTCTATGTCATGGACGATAAAAAAACGATCGCTCAAGTCATCGCTGATTATTCCAAAGAA
TTAAACGATACTTTAGAAATCACTGAGTATGTGCGTTTTGAATTAGGCGAAGGCATTGAGAAAAAGGCAGAGAATTTCGC
TGAAGAAGTGGCTTTGCAAATGAAGTGA

Upstream 100 bases:

>100_bases
ATGCAGATGAAAATAGCGAAGAGATAGAGTTTGTGAGCAATGAATAAAAAGAAGAAATGCTCGCTGAAATCCAAAAAGAA
ATCACTCAAGGAGCCGAATA

Downstream 100 bases:

>100_bases
GTTTTTAAGTGCATTTTGCACTTAAAAACTTTCATGATTTTTAAACAATCCAAATTAACATGCCTTATAGACTAGAAAAA
GACTTCCAAGATTTAATTAC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSEISAQLVKKLRDLTDVGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIASEGVVALEVAPDFKSAVMVEINS
ETDFVAKNEGFKELVKKTLETIKVHNAHTREELLKSSLDNKPFEEYLHSQIAVIGENILVRKIANSKAPSSHIINGYAHS
NARVGVLITMKYNNEKNAPKAVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLVLIAEIEKDNEEAKRLGKPLKNIPT
FGSRIELSDEVLAHQKKVFEDELKEQGKPEKIWDKIVLGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVIADYSKE
LNDTLEITEYVRFELGEGIEKKAENFAEEVALQMK

Sequences:

>Translated_355_residues
MSEISAQLVKKLRDLTDVGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIASEGVVALEVAPDFKSAVMVEINS
ETDFVAKNEGFKELVKKTLETIKVHNAHTREELLKSSLDNKPFEEYLHSQIAVIGENILVRKIANSKAPSSHIINGYAHS
NARVGVLITMKYNNEKNAPKAVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLVLIAEIEKDNEEAKRLGKPLKNIPT
FGSRIELSDEVLAHQKKVFEDELKEQGKPEKIWDKIVLGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVIADYSKE
LNDTLEITEYVRFELGEGIEKKAENFAEEVALQMK
>Mature_354_residues
SEISAQLVKKLRDLTDVGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIASEGVVALEVAPDFKSAVMVEINSE
TDFVAKNEGFKELVKKTLETIKVHNAHTREELLKSSLDNKPFEEYLHSQIAVIGENILVRKIANSKAPSSHIINGYAHSN
ARVGVLITMKYNNEKNAPKAVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLVLIAEIEKDNEEAKRLGKPLKNIPTF
GSRIELSDEVLAHQKKVFEDELKEQGKPEKIWDKIVLGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVIADYSKEL
NDTLEITEYVRFELGEGIEKKAENFAEEVALQMK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=227, Percent_Identity=29.0748898678414, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI291084502, Length=170, Percent_Identity=31.7647058823529, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786366, Length=355, Percent_Identity=35.2112676056338, Blast_Score=183, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17561440, Length=223, Percent_Identity=27.8026905829596, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_HELAH (Q17YZ8)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664127.1
- ProteinModelPortal:   Q17YZ8
- SMR:   Q17YZ8
- STRING:   Q17YZ8
- GeneID:   4176675
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0285
- NMPDR:   fig|382638.8.peg.274
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q17YZ8
- ProtClustDB:   PRK09377
- BioCyc:   HACI382638:HAC_0285-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 39931; Mature: 39799

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEISAQLVKKLRDLTDVGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIASEG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
VVALEVAPDFKSAVMVEINSETDFVAKNEGFKELVKKTLETIKVHNAHTREELLKSSLDN
EEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KPFEEYLHSQIAVIGENILVRKIANSKAPSSHIINGYAHSNARVGVLITMKYNNEKNAPK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECEECCCCEEEEEEEEEECCCCCCHH
AVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLVLIAEIEKDNEEAKRLGKPLKNIPT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCHHHHHHCCCHHHCCC
FGSRIELSDEVLAHQKKVFEDELKEQGKPEKIWDKIVLGKMERFIADNTLIDQRLTLLGQ
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FYVMDDKKTIAQVIADYSKELNDTLEITEYVRFELGEGIEKKAENFAEEVALQMK
HHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEISAQLVKKLRDLTDVGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIASEG
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
VVALEVAPDFKSAVMVEINSETDFVAKNEGFKELVKKTLETIKVHNAHTREELLKSSLDN
EEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KPFEEYLHSQIAVIGENILVRKIANSKAPSSHIINGYAHSNARVGVLITMKYNNEKNAPK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECEECCCCEEEEEEEEEECCCCCCHH
AVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLVLIAEIEKDNEEAKRLGKPLKNIPT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCHHHHHHCCCHHHCCC
FGSRIELSDEVLAHQKKVFEDELKEQGKPEKIWDKIVLGKMERFIADNTLIDQRLTLLGQ
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FYVMDDKKTIAQVIADYSKELNDTLEITEYVRFELGEGIEKKAENFAEEVALQMK
HHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA