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The map label for this gene is gap [H]

Identifier: 109946891

GI number: 109946891

Start: 226568

End: 227560

Strand: Reverse

Name: gap [H]

Synonym: Hac_0275

Alternate gene names: 109946891

Gene position: 227560-226568 (Counterclockwise)

Preceding gene: 109946892

Following gene: 109946890

Centisome position: 14.64

GC content: 40.58

Gene sequence:

>993_bases
ATGCCAATTAAAATCGCTATCAATGGGACAGGGCGTATCGGTTTGTGCACTATAAGAGTTGCCAGTCAAAGAAAAGATAT
AGAAATCGTTGCGATCAATTCTACCGCTGAGATAGAAACGCTATTGCATTTAATCCGCCATGACAGCGTGCATGGGCATT
TTGAAGCCAAGCTGAATGCTGATGGGACTTTAAGTGTTGGGCATAGTAAAAAGATTGTAGTGTTGAGCGAGCGAGATATT
AATAAGCTTGATTTTTCTGTTGTGCAGGCGGAAATTGTCATAGAATGCACCGGTAAATTCAATTCATTAGAAGCTTCAAG
CGCTCATCTTAAAAACAGCGTGAAAAAAGTCATTATCTCTGCTCCTGCCCAAAATACGCCTACCTTTGTCTATGGGGTGA
ATCACACAAGTTACCATAATGAAAGCGTGATTTCTAACGCCTCTTGCACGACTAACGCTACCGCCCCTTTATTAAAAATA
TTAGATGAAGCCTTTGAAGTAGAAAACGCGCTCTTAACGACCATTCATAGCTACACTAACGATCAAAATCTCTTAGACAC
CAAACACAAGGATATTCGGCGCGCTAGAGCGGCTGGCTTAAATCTTATCCCTACAAGCACTGGTGTGAGTAAGGCTATTT
CGCTAGTCTTACCGCATCTAGGCTCTAAGATTACAGGCCTTGCGATTAGAGTGCCTACCCCTAATGTGAGCTTAGTGGAT
TTGTCTTTGAGCTTTAAAAAAGCCGTGAGTAAAGCAAGCCTTCAGCATGCACTTAAAGAATCTTGTAAGCATGCCTTTAA
AGGGATTGTGAGCGTTGATGAAGAAAGGCTTGTTTCAAGCGATTTTATTTCTTCGCCTTTTAGTGCAGTTATTATTGATG
ATCAGATCATGACAATAGGCGAAAAAAATGCTAAAGTATTGGCATGGTATGATAATGAAATAGGTTATAGCGAGCGCTTG
ATAGACATGGTGCAATATATAACGCAAAATTAA

Upstream 100 bases:

>100_bases
GATTTTAGTTTGTGATTAATGTTTGAGACAGAACCCCTTAAGAATGGCTTCATTTAAGAGCATTTGTGATAAAATGTCAA
TTTTTAAATAAAGGGAAAAC

Downstream 100 bases:

>100_bases
AGAAAAGGATTTTTATGTTAGCTAAAATGTCGTTTATGCAAAATGTTAAAAACATTCAAGAAGTGGATGTCAATCATAAA
AAAGTGCTTATTAGAGTGGA

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPIKIAINGTGRIGLCTIRVASQRKDIEIVAINSTAEIETLLHLIRHDSVHGHFEAKLNADGTLSVGHSKKIVVLSERDI
NKLDFSVVQAEIVIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHTSYHNESVISNASCTTNATAPLLKI
LDEAFEVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGSKITGLAIRVPTPNVSLVD
LSLSFKKAVSKASLQHALKESCKHAFKGIVSVDEERLVSSDFISSPFSAVIIDDQIMTIGEKNAKVLAWYDNEIGYSERL
IDMVQYITQN

Sequences:

>Translated_330_residues
MPIKIAINGTGRIGLCTIRVASQRKDIEIVAINSTAEIETLLHLIRHDSVHGHFEAKLNADGTLSVGHSKKIVVLSERDI
NKLDFSVVQAEIVIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHTSYHNESVISNASCTTNATAPLLKI
LDEAFEVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGSKITGLAIRVPTPNVSLVD
LSLSFKKAVSKASLQHALKESCKHAFKGIVSVDEERLVSSDFISSPFSAVIIDDQIMTIGEKNAKVLAWYDNEIGYSERL
IDMVQYITQN
>Mature_329_residues
PIKIAINGTGRIGLCTIRVASQRKDIEIVAINSTAEIETLLHLIRHDSVHGHFEAKLNADGTLSVGHSKKIVVLSERDIN
KLDFSVVQAEIVIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHTSYHNESVISNASCTTNATAPLLKIL
DEAFEVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGSKITGLAIRVPTPNVSLVDL
SLSFKKAVSKASLQHALKESCKHAFKGIVSVDEERLVSSDFISSPFSAVIIDDQIMTIGEKNAKVLAWYDNEIGYSERLI
DMVQYITQN

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=328, Percent_Identity=38.4146341463415, Blast_Score=251, Evalue=8e-67,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=35.8662613981763, Blast_Score=237, Evalue=1e-62,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=40.3614457831325, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=38.2978723404255, Blast_Score=234, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17534679, Length=332, Percent_Identity=39.7590361445783, Blast_Score=268, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17534677, Length=332, Percent_Identity=39.4578313253012, Blast_Score=268, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=39.4578313253012, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=39.4578313253012, Blast_Score=258, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=39.3939393939394, Blast_Score=270, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=38.1818181818182, Blast_Score=256, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=37.8787878787879, Blast_Score=253, Evalue=2e-68,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=42.1538461538462, Blast_Score=271, Evalue=5e-73,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=41.2844036697248, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=41.2844036697248, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=41.2844036697248, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=41.2844036697248, Blast_Score=269, Evalue=2e-72,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 35946; Mature: 35814

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKIAINGTGRIGLCTIRVASQRKDIEIVAINSTAEIETLLHLIRHDSVHGHFEAKLNA
CCEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECC
DGTLSVGHSKKIVVLSERDINKLDFSVVQAEIVIECTGKFNSLEASSAHLKNSVKKVIIS
CCEEEECCCCEEEEEECCCCCHHHHHEEEEEEEEEECCCCCCCCCHHHHHHHHHHHEEEE
APAQNTPTFVYGVNHTSYHNESVISNASCTTNATAPLLKILDEAFEVENALLTTIHSYTN
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGSKITGLAIRVPTPNVSLVD
CCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEE
LSLSFKKAVSKASLQHALKESCKHAFKGIVSVDEERLVSSDFISSPFSAVIIDDQIMTIG
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCEEEEEC
EKNAKVLAWYDNEIGYSERLIDMVQYITQN
CCCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIKIAINGTGRIGLCTIRVASQRKDIEIVAINSTAEIETLLHLIRHDSVHGHFEAKLNA
CEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECC
DGTLSVGHSKKIVVLSERDINKLDFSVVQAEIVIECTGKFNSLEASSAHLKNSVKKVIIS
CCEEEECCCCEEEEEECCCCCHHHHHEEEEEEEEEECCCCCCCCCHHHHHHHHHHHEEEE
APAQNTPTFVYGVNHTSYHNESVISNASCTTNATAPLLKILDEAFEVENALLTTIHSYTN
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGSKITGLAIRVPTPNVSLVD
CCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEE
LSLSFKKAVSKASLQHALKESCKHAFKGIVSVDEERLVSSDFISSPFSAVIIDDQIMTIG
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCEEEEEC
EKNAKVLAWYDNEIGYSERLIDMVQYITQN
CCCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]