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The map label for this gene is corA [H]

Identifier: 109946889

GI number: 109946889

Start: 224373

End: 225329

Strand: Reverse

Name: corA [H]

Synonym: Hac_0273

Alternate gene names: 109946889

Gene position: 225329-224373 (Counterclockwise)

Preceding gene: 109946890

Following gene: 109946888

Centisome position: 14.5

GC content: 36.78

Gene sequence:

>957_bases
ATGGTGAATGTGTTTTTCAAGCAGCAAAAATTTGTCATTAAGAAACGCTTTAACGATTTTAATGGTTTTGATATAGAAGA
AAATGAGGTTTTGTGGTTTGAGTTAATCAACCCCACGCCCAATGAATTGGCGATTTTAAGCCAAGAATACGCTATCCATT
ACAACACAGATCATTCTAACCGCGTTGCTTCAGTCACCAAATACTGGGAAGACAGCTCTAGCGTGACGATTAACGCCTTT
TTCACCAACCAAGATGACCATGAAAGCTTTCATACGGAAATGGCGACCTTTATTTTGTCCAATAACATTCTTTTTACGAT
TTATTATGGAGCGTTAGAGATCTTTGATGCGATCCAAAAAAAGGTGTTAGCGAGCCCTAAAAAATTTGAAGATGGGTTTG
ATATTTTAACGAAAGTTTTTGAAGTGTATTTTGAAAAAGGCGTGGAATGTTTGGAGTGGATCAACAAGCAAACAGGTTTA
TTGCGTAAAAACATCATTTTTAAAGAAAATTCCACGCATGATGATATTTTAATACGCTTGTCCAATTTGCAAGAATTTAA
TATGGCCTTAAGGGATTCTTTTTTTGACAAACGGCGCATTATCACCGCTTTATTAAGAAGCAATAAAGTGGATAGCGATA
CCAAAAATAATCTAAATATCATTTTAACCGATTTTAGCTCGTTAGTGGAGTCTGCCACCGTCAATCTCAACTCGCTTGAT
AATATCCAAAACCTTTTCGCTTCGCAAGTGAATGTGGAGCAAAATGAGATTATTAAGCTTTTCACCGTGGTGACTATGGC
GATGATGCCCCCTACTTTGATTGGCACGATTTATGGCATGAATTTTAAATTCATGCCAGAATTGGAGTGGCAATATGGGT
ATCTTTTCGCGCTGATTATCATGGCGATTTCTACGATTTTACCGGTGATTTATTTCAAAAAGAAGGGTTGGTTATAG

Upstream 100 bases:

>100_bases
TATTTCCACCGGTGGAGGGGCGAGTTTGGAATTATTGGAGGGCAAAATTTTACCTTGTTTTGAGGTTTTGGATAAACGCC
ATTGACTTTAAGGATCACTT

Downstream 100 bases:

>100_bases
CCTTTCATGGATTTTATAACTTCGCTTTTTAACGCCCTTTCCACCATAGATGGCGTTATTTCATTAAGCACGCTCACGCT
TTTAGAGATCATTCTAGGGA

Product: magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELAILSQEYAIHYNTDHSNRVASVTKYWEDSSSVTINAF
FTNQDDHESFHTEMATFILSNNILFTIYYGALEIFDAIQKKVLASPKKFEDGFDILTKVFEVYFEKGVECLEWINKQTGL
LRKNIIFKENSTHDDILIRLSNLQEFNMALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESATVNLNSLD
NIQNLFASQVNVEQNEIIKLFTVVTMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALIIMAISTILPVIYFKKKGWL

Sequences:

>Translated_318_residues
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELAILSQEYAIHYNTDHSNRVASVTKYWEDSSSVTINAF
FTNQDDHESFHTEMATFILSNNILFTIYYGALEIFDAIQKKVLASPKKFEDGFDILTKVFEVYFEKGVECLEWINKQTGL
LRKNIIFKENSTHDDILIRLSNLQEFNMALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESATVNLNSLD
NIQNLFASQVNVEQNEIIKLFTVVTMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALIIMAISTILPVIYFKKKGWL
>Mature_318_residues
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELAILSQEYAIHYNTDHSNRVASVTKYWEDSSSVTINAF
FTNQDDHESFHTEMATFILSNNILFTIYYGALEIFDAIQKKVLASPKKFEDGFDILTKVFEVYFEKGVECLEWINKQTGL
LRKNIIFKENSTHDDILIRLSNLQEFNMALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESATVNLNSLD
NIQNLFASQVNVEQNEIIKLFTVVTMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALIIMAISTILPVIYFKKKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=307, Percent_Identity=26.3843648208469, Blast_Score=134, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37065; Mature: 37065

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELAILSQEYAIHYNTDHSN
CCCEEEHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECEEEEECCCCCC
RVASVTKYWEDSSSVTINAFFTNQDDHESFHTEMATFILSNNILFTIYYGALEIFDAIQK
HHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
KVLASPKKFEDGFDILTKVFEVYFEKGVECLEWINKQTGLLRKNIIFKENSTHDDILIRL
HHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHCEEECCCCCCCCEEEEE
SNLQEFNMALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESATVNLNSLD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHCCCCHHHH
NIQNLFASQVNVEQNEIIKLFTVVTMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALII
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
MAISTILPVIYFKKKGWL
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELAILSQEYAIHYNTDHSN
CCCEEEHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECEEEEECCCCCC
RVASVTKYWEDSSSVTINAFFTNQDDHESFHTEMATFILSNNILFTIYYGALEIFDAIQK
HHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
KVLASPKKFEDGFDILTKVFEVYFEKGVECLEWINKQTGLLRKNIIFKENSTHDDILIRL
HHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHCEEECCCCCCCCEEEEE
SNLQEFNMALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESATVNLNSLD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHCCCCHHHH
NIQNLFASQVNVEQNEIIKLFTVVTMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALII
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
MAISTILPVIYFKKKGWL
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]