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The map label for this gene is nuoC [H]

Identifier: 109946843

GI number: 109946843

Start: 192735

End: 193532

Strand: Reverse

Name: nuoC [H]

Synonym: Hac_0222

Alternate gene names: 109946843

Gene position: 193532-192735 (Counterclockwise)

Preceding gene: 109946844

Following gene: 109946842

Centisome position: 12.45

GC content: 37.84

Gene sequence:

>798_bases
ATGGTAAGAAAACAATCCCCCTATGAAGATGTGCAAAAACAATCACGCCAGCATGACCCCTATAAAATCATAGAGCCTAC
CCCTAAAAAATATTTAGAGGGCAGTGCTTATGAAGTTATCTATAACCACCTTTCTTACAAGCATGAAATTTTAGACAAAT
ACATAGAAACTAACACGGCTGTGTTTTGGATCAAAAAAGAAGATATTTTTTCTATCGCTACGATTTTACGGCATTTGGGG
TATGAATCTTTAAGCGAGATGAGTGCGATAGATTTATGCGCTAAAAAAGGGCATTTTGAATTGTTTTATCAATTTGTGGG
TTTTAGCGACAGTTGTAAAAACCGCCGTAGGGTGCGTATAAAATGCGTTTTATTGCCTAATGAGAGCGTGGATTCTTTAA
GTTTTTTATACCGATCGGCTAATTGGAGCGAAAGGGAAGCGTATGATATGTTTGGCATTGTGTTTGACAAACACCCCTAT
TTAAAACGCCTTATCATGCCGCATGATTGGGTAGGACACCCCTTGTTGCGCTCTTATCCGCTTAAGGGCGATGAATTTGC
CCAATGGTATGAGGTGGATAAGATTTTTGGTAAAGAATACAGAGAAGTGGTGGGTAAAGAGCAACGAGACAGTGCGAGAG
TGGATGAAAAAGACACTTTCAATTTTGCAAAAATTGGCTATGAGCAAGGCAAGGGCGAAGAGTTGAAAGAAATAGAAGAA
AAACATGTGTTTAAAAAAATCCCTTTTGTCAAAGATTTACACAAAATGACCCCTACTATCTTAAAAAAGAGATTATAA

Upstream 100 bases:

>100_bases
CACCACGCCCAGAGACTTTACAATACGCTCTTATGGTTTTGCAAGATAAAATCAGACGCTCTAAAGCGATCAAACAAGAT
GCCCCAAAAAGGTTAGTGTA

Downstream 100 bases:

>100_bases
AATGGCTCAAAATTTCACGAAACTCAACCCCCAATTTGAAAACATCATTTTTGAACATGACGATAACCAAATGGTGCTAA
ACTTTGGCCCCCAACACCCC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTAVFWIKKEDIFSIATILRHLG
YESLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRIKCVLLPNESVDSLSFLYRSANWSEREAYDMFGIVFDKHPY
LKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKEIEE
KHVFKKIPFVKDLHKMTPTILKKRL

Sequences:

>Translated_265_residues
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTAVFWIKKEDIFSIATILRHLG
YESLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRIKCVLLPNESVDSLSFLYRSANWSEREAYDMFGIVFDKHPY
LKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKEIEE
KHVFKKIPFVKDLHKMTPTILKKRL
>Mature_265_residues
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTAVFWIKKEDIFSIATILRHLG
YESLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRIKCVLLPNESVDSLSFLYRSANWSEREAYDMFGIVFDKHPY
LKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKEIEE
KHVFKKIPFVKDLHKMTPTILKKRL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=147, Percent_Identity=29.9319727891156, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI145693162, Length=182, Percent_Identity=31.3186813186813, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=103, Percent_Identity=31.0679611650485, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563621, Length=103, Percent_Identity=31.0679611650485, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24656494, Length=158, Percent_Identity=28.4810126582279, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 31537; Mature: 31537

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTA
CCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCE
VFWIKKEDIFSIATILRHLGYESLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRI
EEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHCCCCCEEEE
KCVLLPNESVDSLSFLYRSANWSEREAYDMFGIVFDKHPYLKRLIMPHDWVGHPLLRSYP
EEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHCC
LKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKEIEE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHH
KHVFKKIPFVKDLHKMTPTILKKRL
HHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTA
CCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCE
VFWIKKEDIFSIATILRHLGYESLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRI
EEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHCCCCCEEEE
KCVLLPNESVDSLSFLYRSANWSEREAYDMFGIVFDKHPYLKRLIMPHDWVGHPLLRSYP
EEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHCC
LKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKEIEE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHH
KHVFKKIPFVKDLHKMTPTILKKRL
HHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA