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The map label for this gene is oxaA [H]

Identifier: 109946792

GI number: 109946792

Start: 144958

End: 146598

Strand: Reverse

Name: oxaA [H]

Synonym: Hac_0169

Alternate gene names: 109946792

Gene position: 146598-144958 (Counterclockwise)

Preceding gene: 109946793

Following gene: 109946791

Centisome position: 9.43

GC content: 38.09

Gene sequence:

>1641_bases
ATGGATAAAAACAATAACACCAATTTGCGCTTGATTTTAGCGATCGCTTTGTCTTTTTTGTTTATCACTCTTTATAGCTA
TTTTTTCCAAAAACCAGACAAAACAACCCCCAAAGAAACAGCAAAGCAAGAAGCAGCGAACAACAACACGGCTTTAAACC
CCAACGCACCCACCACACAAAATTCTAGTGCCGCTCAAGCGATCCCCCAAGAGAGTTTGTTAAGCACCATTTCTTTTGAG
CATGCCAAAATTGAGATTGACTCTCTAGGGCGCATCAAACAGGTTTATCTCAAGAATAAAAAATACCTAACCCCTAAAGA
AAAAGGCTTTTTAGAGCATGTGAGCCATCTTTTTAGCTCCAAAGAAAACACGCAACCTCTCCTAAAAGAGCTCCCCCTTC
TAGGCGATAATTTAAAACCTTTAGAGGTGCGCTTTTTAGACCCTACGCTCAATAACAAAGCGTTCAACACCTCTTATAGC
GCTTCAAAAACCACTCTTGGTCCTAACGAACAGCTGATTTTAACCCAAGATTTAGGCGATCTTACAATCATTAAAACCCT
AACTTTTTATGATGATTTGCATTATGATTTACAAATCGCATTCAAATCGCCTAACAACATTATCCCTAACTATGTGATCA
CCAATGGTTACAGACCGGTGGCTGATTTGGATAGTTACACTTTTTCGGGCGTGCTTTTAGAAAACAATGACAAAAAAATT
GAAAAAATTGAAGATAAAGATGCCAAAGAAATCAAACGCTTTTCCAATATTCGCTTTTTATCTAGCGTGGATAGGTATTT
CACCACCTTGCTTTTTACCGATAACCCTCAAGGTTTTGAAGCCTTAATTGATTCAGAAACCGGCACTAAAAACCCTTTAG
GATTCATTTCTCTTAAAAACGAAGCGACTTTGCATGGCTATATTGGTCCTAAAGATTACCGCTCCTTAAAAGCGATTTCA
CCCATGCTTACCGATGTGATAGAGTATGGCTTGATCACTTTCTTTGCTAAAGGCGTGTTTGTTTTACTAGATTATTTGTA
TCAATTTGTGGGTAATTGGGGTTGGGCTATCATTCTTTTAACTATTGTCGTGCGCATTATCCTCTATCCTTTAAGTTACA
AGGGTATGGTGAGCATGCAAAAACTCAAAGAATTAGCCCCTAAAATGAAAGAACTTCAAGAAAAATACAAAGGCGAACCC
CAAAAATTGCAAGCTAACATGATGCAACTTTACAAAAAACATGGGGCTAACCCATTAGGCGGTTGTCTGCCTTTAATCTT
GCAAATCCCAGTATTTTTTGCGATTTATAGAGTGCTCTATAATGCTGTGGAATTGAAAAGCTCAGAGTGGATTTTATGGA
TCCACGATCTATCCATCATGGATCCGTATTTTATTTTACCGCTTTTTATGGGAGCGTCTATGTATTGGCACCAAAGCGTC
ACGCCAAACACCATGACCGATCCCATGCAAGCGAAGATTTTTAAATTCTTGCCCCTATTATTCACGCTCTTTTTGATCAC
TTTCCCTGCAGGATTAGTCTTGTATTGGATCACGAATAATGTTCTTTCAGTGTTGCAACAACTCATTATCAATAAAGTAT
TAGAAAACAAAAAACACATGCACGAACAAACCAAAAAATAA

Upstream 100 bases:

>100_bases
CTAGCTTGCTCCAATTTAATAAAAATTTTAAAACCATCACTTTTTGGCTTATCCCCACAAAAAGCCATGCGACTTATTAC
ATCATTAAGGTTTAATCACA

Downstream 100 bases:

>100_bases
AGGAAAATTGATGCAAAATTTTATTGAAATCAAAGCCAAAACATTAGAAGAAGCCCTTATCCAAGCTTCTATCACCCTAA
ATTGCCCCATCATCAATTTG

Product: inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MDKNNNTNLRLILAIALSFLFITLYSYFFQKPDKTTPKETAKQEAANNNTALNPNAPTTQNSSAAQAIPQESLLSTISFE
HAKIEIDSLGRIKQVYLKNKKYLTPKEKGFLEHVSHLFSSKENTQPLLKELPLLGDNLKPLEVRFLDPTLNNKAFNTSYS
ASKTTLGPNEQLILTQDLGDLTIIKTLTFYDDLHYDLQIAFKSPNNIIPNYVITNGYRPVADLDSYTFSGVLLENNDKKI
EKIEDKDAKEIKRFSNIRFLSSVDRYFTTLLFTDNPQGFEALIDSETGTKNPLGFISLKNEATLHGYIGPKDYRSLKAIS
PMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTIVVRIILYPLSYKGMVSMQKLKELAPKMKELQEKYKGEP
QKLQANMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLFMGASMYWHQSV
TPNTMTDPMQAKIFKFLPLLFTLFLITFPAGLVLYWITNNVLSVLQQLIINKVLENKKHMHEQTKK

Sequences:

>Translated_546_residues
MDKNNNTNLRLILAIALSFLFITLYSYFFQKPDKTTPKETAKQEAANNNTALNPNAPTTQNSSAAQAIPQESLLSTISFE
HAKIEIDSLGRIKQVYLKNKKYLTPKEKGFLEHVSHLFSSKENTQPLLKELPLLGDNLKPLEVRFLDPTLNNKAFNTSYS
ASKTTLGPNEQLILTQDLGDLTIIKTLTFYDDLHYDLQIAFKSPNNIIPNYVITNGYRPVADLDSYTFSGVLLENNDKKI
EKIEDKDAKEIKRFSNIRFLSSVDRYFTTLLFTDNPQGFEALIDSETGTKNPLGFISLKNEATLHGYIGPKDYRSLKAIS
PMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTIVVRIILYPLSYKGMVSMQKLKELAPKMKELQEKYKGEP
QKLQANMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLFMGASMYWHQSV
TPNTMTDPMQAKIFKFLPLLFTLFLITFPAGLVLYWITNNVLSVLQQLIINKVLENKKHMHEQTKK
>Mature_546_residues
MDKNNNTNLRLILAIALSFLFITLYSYFFQKPDKTTPKETAKQEAANNNTALNPNAPTTQNSSAAQAIPQESLLSTISFE
HAKIEIDSLGRIKQVYLKNKKYLTPKEKGFLEHVSHLFSSKENTQPLLKELPLLGDNLKPLEVRFLDPTLNNKAFNTSYS
ASKTTLGPNEQLILTQDLGDLTIIKTLTFYDDLHYDLQIAFKSPNNIIPNYVITNGYRPVADLDSYTFSGVLLENNDKKI
EKIEDKDAKEIKRFSNIRFLSSVDRYFTTLLFTDNPQGFEALIDSETGTKNPLGFISLKNEATLHGYIGPKDYRSLKAIS
PMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTIVVRIILYPLSYKGMVSMQKLKELAPKMKELQEKYKGEP
QKLQANMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLFMGASMYWHQSV
TPNTMTDPMQAKIFKFLPLLFTLFLITFPAGLVLYWITNNVLSVLQQLIINKVLENKKHMHEQTKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=335, Percent_Identity=37.0149253731343, Blast_Score=245, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24662345, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356443, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 62436; Mature: 62436

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNNNTNLRLILAIALSFLFITLYSYFFQKPDKTTPKETAKQEAANNNTALNPNAPTTQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
NSSAAQAIPQESLLSTISFEHAKIEIDSLGRIKQVYLKNKKYLTPKEKGFLEHVSHLFSS
CCCHHHHCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
KENTQPLLKELPLLGDNLKPLEVRFLDPTLNNKAFNTSYSASKTTLGPNEQLILTQDLGD
CCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCC
LTIIKTLTFYDDLHYDLQIAFKSPNNIIPNYVITNGYRPVADLDSYTFSGVLLENNDKKI
CHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCHHH
EKIEDKDAKEIKRFSNIRFLSSVDRYFTTLLFTDNPQGFEALIDSETGTKNPLGFISLKN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCCCCCCCEEEEECC
EATLHGYIGPKDYRSLKAISPMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILL
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TIVVRIILYPLSYKGMVSMQKLKELAPKMKELQEKYKGEPQKLQANMMQLYKKHGANPLG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCH
GCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLFMGASMYWHQSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCHHHHHHHHHCCHHHEECCC
TPNTMTDPMQAKIFKFLPLLFTLFLITFPAGLVLYWITNNVLSVLQQLIINKVLENKKHM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEQTKK
HHHCCC
>Mature Secondary Structure
MDKNNNTNLRLILAIALSFLFITLYSYFFQKPDKTTPKETAKQEAANNNTALNPNAPTTQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
NSSAAQAIPQESLLSTISFEHAKIEIDSLGRIKQVYLKNKKYLTPKEKGFLEHVSHLFSS
CCCHHHHCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
KENTQPLLKELPLLGDNLKPLEVRFLDPTLNNKAFNTSYSASKTTLGPNEQLILTQDLGD
CCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCC
LTIIKTLTFYDDLHYDLQIAFKSPNNIIPNYVITNGYRPVADLDSYTFSGVLLENNDKKI
CHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCHHH
EKIEDKDAKEIKRFSNIRFLSSVDRYFTTLLFTDNPQGFEALIDSETGTKNPLGFISLKN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCCCCCCCEEEEECC
EATLHGYIGPKDYRSLKAISPMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILL
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TIVVRIILYPLSYKGMVSMQKLKELAPKMKELQEKYKGEPQKLQANMMQLYKKHGANPLG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCH
GCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLFMGASMYWHQSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCHHHHHHHHHCCHHHEECCC
TPNTMTDPMQAKIFKFLPLLFTLFLITFPAGLVLYWITNNVLSVLQQLIINKVLENKKHM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEQTKK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]