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The map label for this gene is sigK [H]

Identifier: 110681128

GI number: 110681128

Start: 3857703

End: 3858239

Strand: Direct

Name: sigK [H]

Synonym: RD1_3999

Alternate gene names: 110681128

Gene position: 3857703-3858239 (Clockwise)

Preceding gene: 110681127

Following gene: 110681130

Centisome position: 93.34

GC content: 57.73

Gene sequence:

>537_bases
ATGGAAGACAAAGACCTCATTGCACGTATTGCTGCTGGCGACAAAGGTGCCATGCGGGACCTCTACACCCGGTATGATCA
GGCCATCTATGCCTTTGCCATGGGGCGCTGCGGAAATGGCGAACTTGCATCAGACTGCGTGCATGACACGATGCTTGATG
TGTGGCGCACCGCATCGCGCTTTGGCGGACAGTCAAGCGTCAAGACCTGGCTGTTTTCGATCGCGCGCAACAAGCTGGTC
GATGCATTGCGCAAACGCGGCAAGCTCTCCTTTGTGGATGAGGTGCCCGAAAGCGCGGATACGGCCCCCGACCCTGAGGC
CGCTGCCATCGCGGCATCGGAAAAGCAACGGCTTCATACCTGTCTGAAGGGGTTGAAAGACGTGCAGCATTCCGCCATCC
GCCTCGCCTTTCTCGAAGACCTGACCTATCCCGAAATCGCGGAAATCGAAGCGGTGCCGGTCGGAACGATCAAAACCCGC
ATCTTTCACGCCAAACAAGCGTTGATGCGGTGTCTCAGCGCTGGTTTGCATCGCTGA

Upstream 100 bases:

>100_bases
TGCAACACGCGCACGCGGTTGTCTCGCTTATGAGTTGTGTCTGCCGATGCGCGATGGCACTTCTTGTCTGCACAAGGATC
TGGACCGGTAAACATCAAAG

Downstream 100 bases:

>100_bases
AGCGGCTGTGTGACGCCCCTGCGCACGTGCCGTCAGATCACTGTTGCACAACCAGTTCGACCAGATCGCTACGCGCATCC
AGCGCAACGGCAGCCTCTTG

Product: RNA polymerase ECF-type sigma factor, putative

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MEDKDLIARIAAGDKGAMRDLYTRYDQAIYAFAMGRCGNGELASDCVHDTMLDVWRTASRFGGQSSVKTWLFSIARNKLV
DALRKRGKLSFVDEVPESADTAPDPEAAAIAASEKQRLHTCLKGLKDVQHSAIRLAFLEDLTYPEIAEIEAVPVGTIKTR
IFHAKQALMRCLSAGLHR

Sequences:

>Translated_178_residues
MEDKDLIARIAAGDKGAMRDLYTRYDQAIYAFAMGRCGNGELASDCVHDTMLDVWRTASRFGGQSSVKTWLFSIARNKLV
DALRKRGKLSFVDEVPESADTAPDPEAAAIAASEKQRLHTCLKGLKDVQHSAIRLAFLEDLTYPEIAEIEAVPVGTIKTR
IFHAKQALMRCLSAGLHR
>Mature_178_residues
MEDKDLIARIAAGDKGAMRDLYTRYDQAIYAFAMGRCGNGELASDCVHDTMLDVWRTASRFGGQSSVKTWLFSIARNKLV
DALRKRGKLSFVDEVPESADTAPDPEAAAIAASEKQRLHTCLKGLKDVQHSAIRLAFLEDLTYPEIAEIEAVPVGTIKTR
IFHAKQALMRCLSAGLHR

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=184, Percent_Identity=27.1739130434783, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 19667; Mature: 19667

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKDLIARIAAGDKGAMRDLYTRYDQAIYAFAMGRCGNGELASDCVHDTMLDVWRTASR
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
FGGQSSVKTWLFSIARNKLVDALRKRGKLSFVDEVPESADTAPDPEAAAIAASEKQRLHT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
CLKGLKDVQHSAIRLAFLEDLTYPEIAEIEAVPVGTIKTRIFHAKQALMRCLSAGLHR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEDKDLIARIAAGDKGAMRDLYTRYDQAIYAFAMGRCGNGELASDCVHDTMLDVWRTASR
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
FGGQSSVKTWLFSIARNKLVDALRKRGKLSFVDEVPESADTAPDPEAAAIAASEKQRLHT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
CLKGLKDVQHSAIRLAFLEDLTYPEIAEIEAVPVGTIKTRIFHAKQALMRCLSAGLHR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]