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The map label for this gene is frpC [H]

Identifier: 110681127

GI number: 110681127

Start: 3855818

End: 3857464

Strand: Direct

Name: frpC [H]

Synonym: RD1_3998

Alternate gene names: 110681127

Gene position: 3855818-3857464 (Clockwise)

Preceding gene: 110681126

Following gene: 110681128

Centisome position: 93.29

GC content: 55.8

Gene sequence:

>1647_bases
ATGTCGATTTTTAATCTTTTCAACCTTTTTTCCAACGGCCTCGACATCAAGGGCTCAAACAAGAGTGACCTGATCATCGG
TTCCTTTGGCAATGACAAGATCGCCGGAAACGGTGGTGATGATTTGATGTTCGGTCTGTTTGGCAATGACAAGATGTCCG
GTGGTCTGGGCGACGACAGGATCTTTGCAGGTGCAGGCCGTGACATCGTCGAAGGCGGCGAGGGCGAAGATGCCCTTTAT
GGCAACAACGGCAATGACGTGATCGTCGGCAACAGAGGCAACGACAAGATGTTCGGCGGATCCGGCAACGACAAGCTGGT
CTGGAACAACGGCGACGGGTCGGACCTGATGAACGGCGGCAGCGGGTATGATAAGGTACAGGTGAATTTCGACACCGACC
TTGTGGATGATGATCTGCAAAACAAGGACGTCGCTGAATTTGAGACGACTGAAACAGGCGTCCAGTTCGCCCGCACCGAA
GTGAATGACCAATCCGAACGCGGTCTGTTCCAACTCGACATTCGCGAAACCGAAGTGCTGGAGACGAATTTCGGCGGCGG
TGATGATACCGCAGTGATCAAGGGCGATGTGCTTGAAAAGATCGCTCTGGACCTTGATGGCGGGGACGGCATCGACACGC
TCGATCTGTCCCAGGTTGATTCGGGCATCAAGGTGGACCTTGCCGCTGGCAAACTGGCGCATTCCAAGGCCGAAAACTTC
GAAAACGTCATTGGCACCGAGTATCAGGATCTGCTCAGGGGCGATGCGCAGGACAATGTCATTTCGGGCCTTGGCGGCGA
TGACCAGCTTGGCGGTCGGGCCGGCAATGACACGTTGATCGGCAACAAGGGCAACGACAAGGTCTTTGGCGGGGACGGCG
ATGATCTGCTGATCTGGAACAATGGCGACGGGTCGGACCTGATGCACGGCGGCAACGGATATGACCGCTTGCAGGTCAAC
TTTGACACGGACCTTGTGAATGACGATCTGCAAAACAAGGATGTCGCCGAGTTTTCCGTGGCGGACATCGGGCTGCAATT
TGCGCGTACCGAGGTGAATGATCAGTCAGAGGCTGGCCTGTTCCAACTCGACGTGCGCAACATTGAAGTGTTGGAGACGA
ACTTTGGCGGCGGCGACGACGCGGCCGTGATCAAGGACAACATCCTCAAGCGGATCGAACTTGAACTGGATGGCGGCGAT
GGCGTGGACCTTCTCGACCTCAGCGACGCAGCATCGGCGGTCACTGTTGATCTTGCGGCAGGCACCATCACCGACGGGGC
GAACACATCCACCGCGATCAATTTCGAGAACGTCACCGGCACCGATTTCAACGACACGATCATCGGCAACGATCAGGACA
ACGTGATCCGCGGTGGTGCCGGAAATGATGTGATGTCAGGCGGTGCGGGTGCAGATACGTTCGTCTTCTTCGAAGAAGAC
GCGGGCGTCGACATCATCCTCGATTTCGAGATCGGCGTGGACAGCCTTCTGTTCCTCACCAACGATCCGGAGGTCACAAC
CGACAGCCTGCTGTCGAACCTGACGCAGACCGGGGACGACGTGGAACTGGCCTTCAACAACAAGGTGATCACATTCGAAG
ACACTGTGGTTTCCGACTTTAACGCCGACGATTTCATGATTGTATAG

Upstream 100 bases:

>100_bases
CAGTTGCGGGGCACTGACACAAGGCCAGAACACCTTGGGCAGGCTTCGGACAGGCGGCGGTGAAATTGAAAACAACGATG
ATATTAGCATGGAGAATCCA

Downstream 100 bases:

>100_bases
TTAACCAGTACTTCCGAGGCGAGTGGCCCCGTCAGCTTTTGGCTGGCGGGGTTACGTTATCTGCCCGGCCACGGTTTGTA
GGTGCGGTGCAATCGCACGG

Product: iron-regulated protein frpC, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MSIFNLFNLFSNGLDIKGSNKSDLIIGSFGNDKIAGNGGDDLMFGLFGNDKMSGGLGDDRIFAGAGRDIVEGGEGEDALY
GNNGNDVIVGNRGNDKMFGGSGNDKLVWNNGDGSDLMNGGSGYDKVQVNFDTDLVDDDLQNKDVAEFETTETGVQFARTE
VNDQSERGLFQLDIRETEVLETNFGGGDDTAVIKGDVLEKIALDLDGGDGIDTLDLSQVDSGIKVDLAAGKLAHSKAENF
ENVIGTEYQDLLRGDAQDNVISGLGGDDQLGGRAGNDTLIGNKGNDKVFGGDGDDLLIWNNGDGSDLMHGGNGYDRLQVN
FDTDLVNDDLQNKDVAEFSVADIGLQFARTEVNDQSEAGLFQLDVRNIEVLETNFGGGDDAAVIKDNILKRIELELDGGD
GVDLLDLSDAASAVTVDLAAGTITDGANTSTAINFENVTGTDFNDTIIGNDQDNVIRGGAGNDVMSGGAGADTFVFFEED
AGVDIILDFEIGVDSLLFLTNDPEVTTDSLLSNLTQTGDDVELAFNNKVITFEDTVVSDFNADDFMIV

Sequences:

>Translated_548_residues
MSIFNLFNLFSNGLDIKGSNKSDLIIGSFGNDKIAGNGGDDLMFGLFGNDKMSGGLGDDRIFAGAGRDIVEGGEGEDALY
GNNGNDVIVGNRGNDKMFGGSGNDKLVWNNGDGSDLMNGGSGYDKVQVNFDTDLVDDDLQNKDVAEFETTETGVQFARTE
VNDQSERGLFQLDIRETEVLETNFGGGDDTAVIKGDVLEKIALDLDGGDGIDTLDLSQVDSGIKVDLAAGKLAHSKAENF
ENVIGTEYQDLLRGDAQDNVISGLGGDDQLGGRAGNDTLIGNKGNDKVFGGDGDDLLIWNNGDGSDLMHGGNGYDRLQVN
FDTDLVNDDLQNKDVAEFSVADIGLQFARTEVNDQSEAGLFQLDVRNIEVLETNFGGGDDAAVIKDNILKRIELELDGGD
GVDLLDLSDAASAVTVDLAAGTITDGANTSTAINFENVTGTDFNDTIIGNDQDNVIRGGAGNDVMSGGAGADTFVFFEED
AGVDIILDFEIGVDSLLFLTNDPEVTTDSLLSNLTQTGDDVELAFNNKVITFEDTVVSDFNADDFMIV
>Mature_547_residues
SIFNLFNLFSNGLDIKGSNKSDLIIGSFGNDKIAGNGGDDLMFGLFGNDKMSGGLGDDRIFAGAGRDIVEGGEGEDALYG
NNGNDVIVGNRGNDKMFGGSGNDKLVWNNGDGSDLMNGGSGYDKVQVNFDTDLVDDDLQNKDVAEFETTETGVQFARTEV
NDQSERGLFQLDIRETEVLETNFGGGDDTAVIKGDVLEKIALDLDGGDGIDTLDLSQVDSGIKVDLAAGKLAHSKAENFE
NVIGTEYQDLLRGDAQDNVISGLGGDDQLGGRAGNDTLIGNKGNDKVFGGDGDDLLIWNNGDGSDLMHGGNGYDRLQVNF
DTDLVNDDLQNKDVAEFSVADIGLQFARTEVNDQSEAGLFQLDVRNIEVLETNFGGGDDAAVIKDNILKRIELELDGGDG
VDLLDLSDAASAVTVDLAAGTITDGANTSTAINFENVTGTDFNDTIIGNDQDNVIRGGAGNDVMSGGAGADTFVFFEEDA
GVDIILDFEIGVDSLLFLTNDPEVTTDSLLSNLTQTGDDVELAFNNKVITFEDTVVSDFNADDFMIV

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 57949; Mature: 57818

Theoretical pI: Translated: 3.60; Mature: 3.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFNLFNLFSNGLDIKGSNKSDLIIGSFGNDKIAGNGGDDLMFGLFGNDKMSGGLGDDR
CCHHHHHHHHHCCCEECCCCCCCEEEEECCCCEECCCCCCCEEEEEECCCCCCCCCCCCC
IFAGAGRDIVEGGEGEDALYGNNGNDVIVGNRGNDKMFGGSGNDKLVWNNGDGSDLMNGG
EEECCCCHHHCCCCCCCCEECCCCCEEEEECCCCCCEECCCCCCEEEEECCCCHHHCCCC
SGYDKVQVNFDTDLVDDDLQNKDVAEFETTETGVQFARTEVNDQSERGLFQLDIRETEVL
CCCCEEEEEECCCCCCCCCCCCCCCCEECCHHHHEEEEECCCCCCCCCEEEEECCCEEEE
ETNFGGGDDTAVIKGDVLEKIALDLDGGDGIDTLDLSQVDSGIKVDLAAGKLAHSKAENF
EECCCCCCCCEEEECHHEEEEEEECCCCCCCCEEEHHHCCCCCEEEEECCHHHHHHHHHH
ENVIGTEYQDLLRGDAQDNVISGLGGDDQLGGRAGNDTLIGNKGNDKVFGGDGDDLLIWN
HHHHCCCHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCEECCCCCCEEECCCCCEEEEEE
NGDGSDLMHGGNGYDRLQVNFDTDLVNDDLQNKDVAEFSVADIGLQFARTEVNDQSEAGL
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEHHHHCEEEEEECCCCCCCCCE
FQLDVRNIEVLETNFGGGDDAAVIKDNILKRIELELDGGDGVDLLDLSDAASAVTVDLAA
EEEECCCEEEEEECCCCCCCCHHHHHCCEEEEEEEECCCCCEEEEECCCCCCEEEEEEEC
GTITDGANTSTAINFENVTGTDFNDTIIGNDQDNVIRGGAGNDVMSGGAGADTFVFFEED
CEECCCCCCCEEEEECCCCCCCCCCCEECCCCCCEEECCCCCCCCCCCCCCCEEEEEECC
AGVDIILDFEIGVDSLLFLTNDPEVTTDSLLSNLTQTGDDVELAFNNKVITFEDTVVSDF
CCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCEEEEEECCEECCC
NADDFMIV
CCCCEEEC
>Mature Secondary Structure 
SIFNLFNLFSNGLDIKGSNKSDLIIGSFGNDKIAGNGGDDLMFGLFGNDKMSGGLGDDR
CHHHHHHHHHCCCEECCCCCCCEEEEECCCCEECCCCCCCEEEEEECCCCCCCCCCCCC
IFAGAGRDIVEGGEGEDALYGNNGNDVIVGNRGNDKMFGGSGNDKLVWNNGDGSDLMNGG
EEECCCCHHHCCCCCCCCEECCCCCEEEEECCCCCCEECCCCCCEEEEECCCCHHHCCCC
SGYDKVQVNFDTDLVDDDLQNKDVAEFETTETGVQFARTEVNDQSERGLFQLDIRETEVL
CCCCEEEEEECCCCCCCCCCCCCCCCEECCHHHHEEEEECCCCCCCCCEEEEECCCEEEE
ETNFGGGDDTAVIKGDVLEKIALDLDGGDGIDTLDLSQVDSGIKVDLAAGKLAHSKAENF
EECCCCCCCCEEEECHHEEEEEEECCCCCCCCEEEHHHCCCCCEEEEECCHHHHHHHHHH
ENVIGTEYQDLLRGDAQDNVISGLGGDDQLGGRAGNDTLIGNKGNDKVFGGDGDDLLIWN
HHHHCCCHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCEECCCCCCEEECCCCCEEEEEE
NGDGSDLMHGGNGYDRLQVNFDTDLVNDDLQNKDVAEFSVADIGLQFARTEVNDQSEAGL
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEHHHHCEEEEEECCCCCCCCCE
FQLDVRNIEVLETNFGGGDDAAVIKDNILKRIELELDGGDGVDLLDLSDAASAVTVDLAA
EEEECCCEEEEEECCCCCCCCHHHHHCCEEEEEEEECCCCCEEEEECCCCCCEEEEEEEC
GTITDGANTSTAINFENVTGTDFNDTIIGNDQDNVIRGGAGNDVMSGGAGADTFVFFEED
CEECCCCCCCEEEEECCCCCCCCCCCEECCCCCCEEECCCCCCCCCCCCCCCEEEEEECC
AGVDIILDFEIGVDSLLFLTNDPEVTTDSLLSNLTQTGDDVELAFNNKVITFEDTVVSDF
CCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCEEEEEECCEECCC
NADDFMIV
CCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]