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The map label for this gene is deh [C]

Identifier: 110681065

GI number: 110681065

Start: 3792019

End: 3792705

Strand: Direct

Name: deh [C]

Synonym: RD1_3929

Alternate gene names: 110681065

Gene position: 3792019-3792705 (Clockwise)

Preceding gene: 110681062

Following gene: 110681066

Centisome position: 91.75

GC content: 57.5

Gene sequence:

>687_bases
ATGGCCATTAAGACATGCGTTTTTGATGCCTATGGTACGCTTTTCGATGTTGCGGCGGCGGCACGGCAGGCGGCCTGCGA
ACCCGATTTCAACCATATTTCCGACAGCTGGCCCGTTCTGGCGGAAAACTGGCGGCAGAAACAACTGCAATACACCTGGC
TGCGCGCTGTTGTCGGGGCGCATGATGACTTTTGGACCATCACCCAGGAAGGGCTGGATTGGGCCCTGGAAAAATCCGGG
CATGCGCAGGACGCGGCCTTGCGCGAACGCCTGTTGGCGCTTTACTGGGAACTTCAGAGCTATCCCGAAGTGCCGATGAT
GCTGGCGAGGCTGAAAGAGGCGGGGCTGAACACGGCAATCCTGTCCAACGGATCGCCCGACATGCTTGCCGGTGCGGTTC
AGTCGGCGGGTATTGACGCATACCTTGATGATGTTTTGTCGGTTGAAAGCGTGGCCGTTTTCAAACCGGATGCGCGGGTC
TATGATCTGGTGCTCAAGAGGTTCGGCGGCGACCTCGGTGACGTTCTGTTTGTCTCGTCCAACGGCTGGGATGCCGCATG
CGCCACAGGCTACGGGTTTCAAACCGCATGGGTCAATCGCGCGAGTGACCCGGTGGACAGGTTGCCATGGCGCCCAGAAC
ATGTGTTGAATGATTTGCGGAAAATCCCCGAAATTGCAGGAATATAA

Upstream 100 bases:

>100_bases
GTCCGCCGGATCAGTAAACCCGAAAACGCGCCCTTTTCGCCCTTTTACAATGCAACGGCCCGTGACACTCTGGCCCCGAC
AGCAGGAAAGGAATGTGCAA

Downstream 100 bases:

>100_bases
TGCCACATTTCACAACCTCAGACGGGCTTTCCCTCTATTACACAGACGAAGGCGACGGTTTGCCGATCCTTTGTCTGTCG
GGGCTGACGCGCACGTCAAA

Product: (S)-2-haloacid dehalogenase

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase I; DEHCI; Halocarboxylic acid halidohydrolase I; L-2-haloacid dehalogenase I [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MAIKTCVFDAYGTLFDVAAAARQAACEPDFNHISDSWPVLAENWRQKQLQYTWLRAVVGAHDDFWTITQEGLDWALEKSG
HAQDAALRERLLALYWELQSYPEVPMMLARLKEAGLNTAILSNGSPDMLAGAVQSAGIDAYLDDVLSVESVAVFKPDARV
YDLVLKRFGGDLGDVLFVSSNGWDAACATGYGFQTAWVNRASDPVDRLPWRPEHVLNDLRKIPEIAGI

Sequences:

>Translated_228_residues
MAIKTCVFDAYGTLFDVAAAARQAACEPDFNHISDSWPVLAENWRQKQLQYTWLRAVVGAHDDFWTITQEGLDWALEKSG
HAQDAALRERLLALYWELQSYPEVPMMLARLKEAGLNTAILSNGSPDMLAGAVQSAGIDAYLDDVLSVESVAVFKPDARV
YDLVLKRFGGDLGDVLFVSSNGWDAACATGYGFQTAWVNRASDPVDRLPWRPEHVLNDLRKIPEIAGI
>Mature_227_residues
AIKTCVFDAYGTLFDVAAAARQAACEPDFNHISDSWPVLAENWRQKQLQYTWLRAVVGAHDDFWTITQEGLDWALEKSGH
AQDAALRERLLALYWELQSYPEVPMMLARLKEAGLNTAILSNGSPDMLAGAVQSAGIDAYLDDVLSVESVAVFKPDARVY
DLVLKRFGGDLGDVLFVSSNGWDAACATGYGFQTAWVNRASDPVDRLPWRPEHVLNDLRKIPEIAGI

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 25245; Mature: 25113

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKTCVFDAYGTLFDVAAAARQAACEPDFNHISDSWPVLAENWRQKQLQYTWLRAVVGA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
HDDFWTITQEGLDWALEKSGHAQDAALRERLLALYWELQSYPEVPMMLARLKEAGLNTAI
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
LSNGSPDMLAGAVQSAGIDAYLDDVLSVESVAVFKPDARVYDLVLKRFGGDLGDVLFVSS
ECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCEEEEEC
NGWDAACATGYGFQTAWVNRASDPVDRLPWRPEHVLNDLRKIPEIAGI
CCCCCHHHCCCCCHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIKTCVFDAYGTLFDVAAAARQAACEPDFNHISDSWPVLAENWRQKQLQYTWLRAVVGA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
HDDFWTITQEGLDWALEKSGHAQDAALRERLLALYWELQSYPEVPMMLARLKEAGLNTAI
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
LSNGSPDMLAGAVQSAGIDAYLDDVLSVESVAVFKPDARVYDLVLKRFGGDLGDVLFVSS
ECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCEEEEEC
NGWDAACATGYGFQTAWVNRASDPVDRLPWRPEHVLNDLRKIPEIAGI
CCCCCHHHCCCCCHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1995594 [H]