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The map label for this gene is aatA [H]

Identifier: 110681031

GI number: 110681031

Start: 3760476

End: 3761678

Strand: Direct

Name: aatA [H]

Synonym: RD1_3892

Alternate gene names: 110681031

Gene position: 3760476-3761678 (Clockwise)

Preceding gene: 110681027

Following gene: 110681034

Centisome position: 90.98

GC content: 59.27

Gene sequence:

>1203_bases
ATGGAATTCCTGTCTACGACGCTCGCGCGCGTCAAACCGTCTCCGACGATTGCTGTTACCACCAAAGCGGCCGAACTGAA
GGCCGCTGGCCGTGATATCATAGGCCTTGGCGCGGGCGAGCCTGATTTCGACACACCGCAGAACATCAAAGACGCTGCCG
TGGCAGCCATAACAGCCGGAAAGACAAAATACACGGCTGTTGACGGCATTCCCGAGCTGAAACAGGCCATCTGCGACAAA
TTGCACCGCGATAATGGCCTCAGCTACACCCCTTCGCAGGTCAGTGTCGGCACCGGGGGTAAACAGATCCTCTATAATGC
GCTGATGGCCACGCTGAACGAAGGCGACGAGGTCGTGATCCCTGCCCCCTATTGGGTCAGCTATCCGGATATGGTGCTGC
TGGCGGGCGGTGAACCTGTCATCGCCGAAGCCTCGCTGCAAACCGGGTTCAAGCTGACAGCGGATCAGCTTGAGGCGGTG
ATTACGGATAAAACCAAATGGCTGATCTTCAACTCGCCCTCGAACCCGACCGGTGCGGGCTATACCTGGGACGAACTCAA
GGCGCTGACGGATGTGTTGATGCGTCACCCGCATGTCTGGGTGATGACCGACGATATGTATGAACACCTCGTCTATGACG
ATTTCAAATTCTGCACCCCGGCGCAGGTCGAACCACGCCTTTATGAGCGCACGCTGACGGTGAACGGGGTCTCCAAGGCC
TACGCCATGACGGGCTGGCGGATCGGCTACGCCGCAGGGCCGGAGCAGTTGATTGGCGCCATGCGCAAGGTACAGTCGCA
ATCCACGTCGAACCCCTGCTCGGTCAGTCAATGGGCCGCGGTCGAAGCGCTGAACGGTACGCAGGATTTCATCGCGCCCA
ACAATGAGATGTTCGCGCGCCGCCGCGATCTGGTGGTAAAAATGCTGAACGAGGCCGAAGGCATCCGCTGCCCGGTGCCC
GATGGCGCGTTTTATGTCTATCCGTCAATCGCGGGTCTGATCGGTAAAACCTCAGCTGCGGGCACATTGATCGACACGGA
TGAAGCCTTTGCCACGGCGCTCCTCGAAGAGACCGGCGTGGCGGTGGTCTTTGGCGCAGCCTTTGGCCTCTCGCCGAACT
TCCGGGTCAGCTATGCGACCTCGGATGCGGCCTTGACCGAAGCCTGCAGCCGCATTCAAACGTTCTGCGCCAAACTTACG
TGA

Upstream 100 bases:

>100_bases
TCATTAAAATCGTCCATTTTGTATTCTCCTGCGCAGTCGCGCTTGATCGGAGGCCTGCCGCCCCCTAAGAACGCCTCAGT
CATATCAAACCGAGGCCCTC

Downstream 100 bases:

>100_bases
ACACGATCAGGGCGGCGGCGCGAAAGTGCCCCGCCACGGCAACCGCCGGGGGCAGCGCATGAATTGTGGTGTTGATCCGT
TAAGGATGTGCCAGCGCGCC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MEFLSTTLARVKPSPTIAVTTKAAELKAAGRDIIGLGAGEPDFDTPQNIKDAAVAAITAGKTKYTAVDGIPELKQAICDK
LHRDNGLSYTPSQVSVGTGGKQILYNALMATLNEGDEVVIPAPYWVSYPDMVLLAGGEPVIAEASLQTGFKLTADQLEAV
ITDKTKWLIFNSPSNPTGAGYTWDELKALTDVLMRHPHVWVMTDDMYEHLVYDDFKFCTPAQVEPRLYERTLTVNGVSKA
YAMTGWRIGYAAGPEQLIGAMRKVQSQSTSNPCSVSQWAAVEALNGTQDFIAPNNEMFARRRDLVVKMLNEAEGIRCPVP
DGAFYVYPSIAGLIGKTSAAGTLIDTDEAFATALLEETGVAVVFGAAFGLSPNFRVSYATSDAALTEACSRIQTFCAKLT

Sequences:

>Translated_400_residues
MEFLSTTLARVKPSPTIAVTTKAAELKAAGRDIIGLGAGEPDFDTPQNIKDAAVAAITAGKTKYTAVDGIPELKQAICDK
LHRDNGLSYTPSQVSVGTGGKQILYNALMATLNEGDEVVIPAPYWVSYPDMVLLAGGEPVIAEASLQTGFKLTADQLEAV
ITDKTKWLIFNSPSNPTGAGYTWDELKALTDVLMRHPHVWVMTDDMYEHLVYDDFKFCTPAQVEPRLYERTLTVNGVSKA
YAMTGWRIGYAAGPEQLIGAMRKVQSQSTSNPCSVSQWAAVEALNGTQDFIAPNNEMFARRRDLVVKMLNEAEGIRCPVP
DGAFYVYPSIAGLIGKTSAAGTLIDTDEAFATALLEETGVAVVFGAAFGLSPNFRVSYATSDAALTEACSRIQTFCAKLT
>Mature_400_residues
MEFLSTTLARVKPSPTIAVTTKAAELKAAGRDIIGLGAGEPDFDTPQNIKDAAVAAITAGKTKYTAVDGIPELKQAICDK
LHRDNGLSYTPSQVSVGTGGKQILYNALMATLNEGDEVVIPAPYWVSYPDMVLLAGGEPVIAEASLQTGFKLTADQLEAV
ITDKTKWLIFNSPSNPTGAGYTWDELKALTDVLMRHPHVWVMTDDMYEHLVYDDFKFCTPAQVEPRLYERTLTVNGVSKA
YAMTGWRIGYAAGPEQLIGAMRKVQSQSTSNPCSVSQWAAVEALNGTQDFIAPNNEMFARRRDLVVKMLNEAEGIRCPVP
DGAFYVYPSIAGLIGKTSAAGTLIDTDEAFATALLEETGVAVVFGAAFGLSPNFRVSYATSDAALTEACSRIQTFCAKLT

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=401, Percent_Identity=25.6857855361596, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI169881279, Length=401, Percent_Identity=25.6857855361596, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI56713254, Length=328, Percent_Identity=29.2682926829268, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI56713256, Length=363, Percent_Identity=27.8236914600551, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI169881281, Length=398, Percent_Identity=23.1155778894472, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4507369, Length=412, Percent_Identity=25, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1786816, Length=376, Percent_Identity=27.3936170212766, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788722, Length=382, Percent_Identity=31.6753926701571, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788627, Length=362, Percent_Identity=26.5193370165746, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=374, Percent_Identity=29.4117647058824, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=374, Percent_Identity=29.4117647058824, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=397, Percent_Identity=26.1964735516373, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=336, Percent_Identity=25, Blast_Score=102, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=26.1964735516373, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=344, Percent_Identity=24.4186046511628, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=342, Percent_Identity=23.3918128654971, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573069, Length=364, Percent_Identity=26.6483516483516, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646114, Length=364, Percent_Identity=26.6483516483516, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573067, Length=364, Percent_Identity=26.6483516483516, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573065, Length=364, Percent_Identity=26.6483516483516, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18859735, Length=317, Percent_Identity=24.6056782334385, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43030; Mature: 43030

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLSTTLARVKPSPTIAVTTKAAELKAAGRDIIGLGAGEPDFDTPQNIKDAAVAAITAG
CCHHHHHHHHCCCCCCEEEEECHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHEEEECC
KTKYTAVDGIPELKQAICDKLHRDNGLSYTPSQVSVGTGGKQILYNALMATLNEGDEVVI
CCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEE
PAPYWVSYPDMVLLAGGEPVIAEASLQTGFKLTADQLEAVITDKTKWLIFNSPSNPTGAG
CCCCEECCCCEEEEECCCCEEEECCCCCCCEECHHHHHHHEECCEEEEEEECCCCCCCCC
YTWDELKALTDVLMRHPHVWVMTDDMYEHLVYDDFKFCTPAQVEPRLYERTLTVNGVSKA
CCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCHHH
YAMTGWRIGYAAGPEQLIGAMRKVQSQSTSNPCSVSQWAAVEALNGTQDFIAPNNEMFAR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHCCCCHHHHHH
RRDLVVKMLNEAEGIRCPVPDGAFYVYPSIAGLIGKTSAAGTLIDTDEAFATALLEETGV
HHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHCCCCCCCCEEECHHHHHHHHHHHCCE
AVVFGAAFGLSPNFRVSYATSDAALTEACSRIQTFCAKLT
EEEEEEHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFLSTTLARVKPSPTIAVTTKAAELKAAGRDIIGLGAGEPDFDTPQNIKDAAVAAITAG
CCHHHHHHHHCCCCCCEEEEECHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHEEEECC
KTKYTAVDGIPELKQAICDKLHRDNGLSYTPSQVSVGTGGKQILYNALMATLNEGDEVVI
CCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEE
PAPYWVSYPDMVLLAGGEPVIAEASLQTGFKLTADQLEAVITDKTKWLIFNSPSNPTGAG
CCCCEECCCCEEEEECCCCEEEECCCCCCCEECHHHHHHHEECCEEEEEEECCCCCCCCC
YTWDELKALTDVLMRHPHVWVMTDDMYEHLVYDDFKFCTPAQVEPRLYERTLTVNGVSKA
CCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCHHH
YAMTGWRIGYAAGPEQLIGAMRKVQSQSTSNPCSVSQWAAVEALNGTQDFIAPNNEMFAR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHCCCCHHHHHH
RRDLVVKMLNEAEGIRCPVPDGAFYVYPSIAGLIGKTSAAGTLIDTDEAFATALLEETGV
HHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHCCCCCCCCEEECHHHHHHHHHHHCCE
AVVFGAAFGLSPNFRVSYATSDAALTEACSRIQTFCAKLT
EEEEEEHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]