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The map label for this gene is ureC

Identifier: 110680944

GI number: 110680944

Start: 3674337

End: 3676046

Strand: Direct

Name: ureC

Synonym: RD1_3800

Alternate gene names: 110680944

Gene position: 3674337-3676046 (Clockwise)

Preceding gene: 110680943

Following gene: 110680945

Centisome position: 88.9

GC content: 62.05

Gene sequence:

>1710_bases
ATGCCCACCAAAATCCCCCGCACCAACTACGCCGCCATGTTCGGACCCACCACCGGTGACAAGGTGCGTCTTGCTGACAC
CGACCTCATCATCGAGGTTGAGCGCGACCACACCATCTATGGCGAGGAGGTCAAGTTCGGCGGGGGCAAGGTCATCCGCG
ACGGGATGGGGCAGTCTCAGGTCACGCGCGCGCAAGGGGCCATGGACACGGTCATCACCAACGCGCTGATCGTGGATCAC
ACGGGCATCTACAAGGCGGATGTCGGCCTGCGCGACGGGCGCATTGCCAGGATCGGCAAGGCGGGCAATCCCGATACGCA
ACCGGGTGTAGACATCATCATCGGCCCCTCGACCGAGGCCATCGCGGGCGAAGGCAAGATCCTGACCGCGGGCGGGTTCG
ACAGCCATATCCACTTCATCGCGCCGCAGCAGATCGACGACGCGCTACATTCAGGCGTGACCACGATGCTCGGCGGTGGC
ACCGGTCCTGCACATGGCACGCTGGCCACCACCTGCACACCGGGATCCTGGCACATCGGTCGGATGTTGCAGGCGTTGGA
TGCCTTCCCCATGAACTTTGGCATCTCGGGCAAAGGGAACGCGTCGCAACCGGCGGCCCTCGTCGAGATGATCGAAGGCG
GCGCCTGCGCGATGAAACTGCACGAGGACTGGGGCACGACACCGGGGGCCATCGACTGCTGCCTGTCCGTGGCTGACGAC
ATGGACGTGCAGGTGATGATCCACACCGATACGCTTAATGAATCCGGGTTCGTCGAAAACACCGTGGCCGCCATCAAGGG
CCGCACGATCCACGCCTTTCACACCGAGGGCGCAGGCGGCGGGCATGCGCCGGATATCATCAAGATCTGTGGCGATGCGA
ATGTCTTGCCCTCCTCGACCAACCCGACGCGTCCCTTCACGGTGAACACGCTCGAAGAACACCTCGACATGCTGATGGTC
TGCCACCACCTCGACAAATCCATCCCCGAAGACGTCGCCTTTGCCGAAAGCCGCATCCGCCGCGAGACCATTGCCGCCGA
AGACATCCTGCACGACATGGGCGCATTTTCGATCATCGCGAGCGACAGTCAGGCCATGGGACGCGTGGGCGAGGTCATCA
TCCGCACGTGGCAGACCGCCGACAAGATGAAGAAACAGCGCGGCGCACTGACCGAGGAAACAGGCGACAACGACAACATG
CGCGTACGCCGCTACATCGCGAAATACACGATCAATCCCGCCATCGCACACGGCATTGCCCACGAGATCGGCAGCATAGA
GGTCGGCAAACGCGCTGATCTCTGCCTGTGGAACCCTGCGTTCTTTGGCGTGAAACCAGAAATGGTGCTGATGGCAGGCA
CCATCGTCTGCGCGCAGATGGGCGACACTAACGCCTCCATCCCCACACCGCAGCCGGTCTATTCACGCCCTATGTTCGGG
GCCTTCGGGCGATCGGTCGAACGTTCCGCCGTTCTGTTTGTAAGCGGTGCAGCCAAATCCGCAAACATCGGCGAGACGCT
GGGCCTGCGCAAGGAACTCATCGCCGTCAAAGGCACGCGCGGGATCGGCAAGAAGGACCTGATCCTGAACGACGCCCTGC
CCCATATCGAGGTAAACCCCGAAACCTACGAGGTCCGCGCCGATGGGGAATTATTGACCTGCCAACCCGCCGAAGTGCTG
CCCATGGCGCAGCGGTATTTTCTGTTTTGA

Upstream 100 bases:

>100_bases
GTTTTTTCGCTTTTGTGTTTTCATCACCAATGCGGACAAAAAAAATTTTCCCAATAATTTCCTTACCTTAGACCAATAAG
CAGAAAAAATCGGAGTGAGC

Downstream 100 bases:

>100_bases
CCGGGCTCGAAAACCCAGAGTTCGCTTGGATTGATGCTGAACCATTAGACGGGCGCGACACGTACATCGATACGATTCTA
AAATGCACTGAACTGGAAAA

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MPTKIPRTNYAAMFGPTTGDKVRLADTDLIIEVERDHTIYGEEVKFGGGKVIRDGMGQSQVTRAQGAMDTVITNALIVDH
TGIYKADVGLRDGRIARIGKAGNPDTQPGVDIIIGPSTEAIAGEGKILTAGGFDSHIHFIAPQQIDDALHSGVTTMLGGG
TGPAHGTLATTCTPGSWHIGRMLQALDAFPMNFGISGKGNASQPAALVEMIEGGACAMKLHEDWGTTPGAIDCCLSVADD
MDVQVMIHTDTLNESGFVENTVAAIKGRTIHAFHTEGAGGGHAPDIIKICGDANVLPSSTNPTRPFTVNTLEEHLDMLMV
CHHLDKSIPEDVAFAESRIRRETIAAEDILHDMGAFSIIASDSQAMGRVGEVIIRTWQTADKMKKQRGALTEETGDNDNM
RVRRYIAKYTINPAIAHGIAHEIGSIEVGKRADLCLWNPAFFGVKPEMVLMAGTIVCAQMGDTNASIPTPQPVYSRPMFG
AFGRSVERSAVLFVSGAAKSANIGETLGLRKELIAVKGTRGIGKKDLILNDALPHIEVNPETYEVRADGELLTCQPAEVL
PMAQRYFLF

Sequences:

>Translated_569_residues
MPTKIPRTNYAAMFGPTTGDKVRLADTDLIIEVERDHTIYGEEVKFGGGKVIRDGMGQSQVTRAQGAMDTVITNALIVDH
TGIYKADVGLRDGRIARIGKAGNPDTQPGVDIIIGPSTEAIAGEGKILTAGGFDSHIHFIAPQQIDDALHSGVTTMLGGG
TGPAHGTLATTCTPGSWHIGRMLQALDAFPMNFGISGKGNASQPAALVEMIEGGACAMKLHEDWGTTPGAIDCCLSVADD
MDVQVMIHTDTLNESGFVENTVAAIKGRTIHAFHTEGAGGGHAPDIIKICGDANVLPSSTNPTRPFTVNTLEEHLDMLMV
CHHLDKSIPEDVAFAESRIRRETIAAEDILHDMGAFSIIASDSQAMGRVGEVIIRTWQTADKMKKQRGALTEETGDNDNM
RVRRYIAKYTINPAIAHGIAHEIGSIEVGKRADLCLWNPAFFGVKPEMVLMAGTIVCAQMGDTNASIPTPQPVYSRPMFG
AFGRSVERSAVLFVSGAAKSANIGETLGLRKELIAVKGTRGIGKKDLILNDALPHIEVNPETYEVRADGELLTCQPAEVL
PMAQRYFLF
>Mature_568_residues
PTKIPRTNYAAMFGPTTGDKVRLADTDLIIEVERDHTIYGEEVKFGGGKVIRDGMGQSQVTRAQGAMDTVITNALIVDHT
GIYKADVGLRDGRIARIGKAGNPDTQPGVDIIIGPSTEAIAGEGKILTAGGFDSHIHFIAPQQIDDALHSGVTTMLGGGT
GPAHGTLATTCTPGSWHIGRMLQALDAFPMNFGISGKGNASQPAALVEMIEGGACAMKLHEDWGTTPGAIDCCLSVADDM
DVQVMIHTDTLNESGFVENTVAAIKGRTIHAFHTEGAGGGHAPDIIKICGDANVLPSSTNPTRPFTVNTLEEHLDMLMVC
HHLDKSIPEDVAFAESRIRRETIAAEDILHDMGAFSIIASDSQAMGRVGEVIIRTWQTADKMKKQRGALTEETGDNDNMR
VRRYIAKYTINPAIAHGIAHEIGSIEVGKRADLCLWNPAFFGVKPEMVLMAGTIVCAQMGDTNASIPTPQPVYSRPMFGA
FGRSVERSAVLFVSGAAKSANIGETLGLRKELIAVKGTRGIGKKDLILNDALPHIEVNPETYEVRADGELLTCQPAEVLP
MAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_ROSDO (Q161S8)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683951.1
- ProteinModelPortal:   Q161S8
- SMR:   Q161S8
- STRING:   Q161S8
- GeneID:   4198846
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3800
- NMPDR:   fig|375451.6.peg.3531
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   RDEN375451:RD1_3800-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 60830; Mature: 60699

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 322-322 BINDING 221-221

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTKIPRTNYAAMFGPTTGDKVRLADTDLIIEVERDHTIYGEEVKFGGGKVIRDGMGQSQ
CCCCCCCCCEEEEECCCCCCEEEEECCEEEEEECCCCEEECCEEEECCCEEEECCCCHHH
VTRAQGAMDTVITNALIVDHTGIYKADVGLRDGRIARIGKAGNPDTQPGVDIIIGPSTEA
HHHHHHHHHHHHHCEEEEECCCCEEECCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCC
IAGEGKILTAGGFDSHIHFIAPQQIDDALHSGVTTMLGGGTGPAHGTLATTCTPGSWHIG
CCCCCEEEEECCCCCCEEEECHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCCHHH
RMLQALDAFPMNFGISGKGNASQPAALVEMIEGGACAMKLHEDWGTTPGAIDCCLSVADD
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEHHCCCCCHHHHHHHHHCCC
MDVQVMIHTDTLNESGFVENTVAAIKGRTIHAFHTEGAGGGHAPDIIKICGDANVLPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCC
NPTRPFTVNTLEEHLDMLMVCHHLDKSIPEDVAFAESRIRRETIAAEDILHDMGAFSIIA
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SDSQAMGRVGEVIIRTWQTADKMKKQRGALTEETGDNDNMRVRRYIAKYTINPAIAHGIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
HEIGSIEVGKRADLCLWNPAFFGVKPEMVLMAGTIVCAQMGDTNASIPTPQPVYSRPMFG
HHHCCEEECCCCCEEEECCHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHCCCCHH
AFGRSVERSAVLFVSGAAKSANIGETLGLRKELIAVKGTRGIGKKDLILNDALPHIEVNP
HHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHEEEECCCCCCCCCEEEECCCCCEEECC
ETYEVRADGELLTCQPAEVLPMAQRYFLF
CEEEEEECCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
PTKIPRTNYAAMFGPTTGDKVRLADTDLIIEVERDHTIYGEEVKFGGGKVIRDGMGQSQ
CCCCCCCCEEEEECCCCCCEEEEECCEEEEEECCCCEEECCEEEECCCEEEECCCCHHH
VTRAQGAMDTVITNALIVDHTGIYKADVGLRDGRIARIGKAGNPDTQPGVDIIIGPSTEA
HHHHHHHHHHHHHCEEEEECCCCEEECCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCC
IAGEGKILTAGGFDSHIHFIAPQQIDDALHSGVTTMLGGGTGPAHGTLATTCTPGSWHIG
CCCCCEEEEECCCCCCEEEECHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCCHHH
RMLQALDAFPMNFGISGKGNASQPAALVEMIEGGACAMKLHEDWGTTPGAIDCCLSVADD
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEHHCCCCCHHHHHHHHHCCC
MDVQVMIHTDTLNESGFVENTVAAIKGRTIHAFHTEGAGGGHAPDIIKICGDANVLPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCC
NPTRPFTVNTLEEHLDMLMVCHHLDKSIPEDVAFAESRIRRETIAAEDILHDMGAFSIIA
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SDSQAMGRVGEVIIRTWQTADKMKKQRGALTEETGDNDNMRVRRYIAKYTINPAIAHGIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
HEIGSIEVGKRADLCLWNPAFFGVKPEMVLMAGTIVCAQMGDTNASIPTPQPVYSRPMFG
HHHCCEEECCCCCEEEECCHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHCCCCHH
AFGRSVERSAVLFVSGAAKSANIGETLGLRKELIAVKGTRGIGKKDLILNDALPHIEVNP
HHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHEEEECCCCCCCCCEEEECCCCCEEECC
ETYEVRADGELLTCQPAEVLPMAQRYFLF
CEEEEEECCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA