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The map label for this gene is xylA

Identifier: 110680856

GI number: 110680856

Start: 3575033

End: 3576334

Strand: Direct

Name: xylA

Synonym: RD1_3705

Alternate gene names: 110680856

Gene position: 3575033-3576334 (Clockwise)

Preceding gene: 110680855

Following gene: 110680861

Centisome position: 86.5

GC content: 57.37

Gene sequence:

>1302_bases
ATGACCGATTTCTTCAAGGACATCCCCGCCATCCGCTATGAGGGACCCGATACCGAGAACGAATTTGCGTTCCGGCACTA
TAATCCGGATGAGGTCGTCATGGGCAAGACGCTCAAGGATCACTTGCGGTTTGCCTGCGCCTATTGGCACAGTTTTGCAT
GGCCGGGCGGCGACCCCTTTGGCGGGCAGACCTTTGAGCGTCCGTGGTTCGGGGACACGATGGAGCTGGCGAAACTCAAG
GCGGACGTCGCCTTTGACATGTTTGAACGTCTGGGCGTGCCCTATTTCTGTTTTCACGATGCAGACGTACGCCCCGAAGG
CGACACCTTTGCCGAAAGCACCAAGAACCTCGAAGAAATCACCGACTATTTCGCCGAAAAAATGGACGCAACAGGCGTCA
AACTGCTGTGGGGAACGGCCAATCTGTTCTCGCATCGCCGCTTTATGGCCGGGGCGGCGACCAATCCCGACCCCGAGGTT
TTTGCCTATTCCGCCGCGACGATCAAATCCTGCATGGATGCGACCCGGAAACTGGGCGGCGAGAACTATGTGCTCTGGGG
CGGGCGCGAAGGCTATGAAACGCTGCTCAACACCGACATGGCCCGCGAACGCGCGCAGGCGGGCCGTATGTTGCAAATGG
TGGTCGATTACAAGCACAAGACCGGTTTTGCAGGCACCATCCTGATCGAACCCAAACCGCAGGAACCGACCAAGCACCAG
TATGATTACGATGTGGCGACGGTCTATGGCTTCCTCAAGGATTTCGGCCTCGAAGGTGAGGTCAAAGTCAACATCGAACA
GGGCCATGCCATTCTTGCAGGCCATAGTTTTGAACATGAGTTGGCGCTCGCACGGGCACTGGGGATTTTCGGCTCGATCG
ACATGAACCGCAATGACTACCAATCCGGCTGGGATACCGACCAGTTTCCAAACAATGTCCCCGAGATGGCGCTTGCCTAT
TACGAAGTTCTGCGCGCCGGGGGCTTCGACACAGGGGGCACCAATTTTGATGCCAAGCTGCGCCGGCAATCGCTTGACCC
GGCGGATCTGATCCTTGCGCATGTGGGTGGTATGGATGCATGCGCTGCGGGGTTAAAGGCCGCTGCGGCCATGCTGGAGG
ATGGCAAGCTAGAGGCCGCGCGCGAGGCGCGCTATGCAGGCTGGTCAGAAGGTTTGGGGCAAAAACTGCTGACCTCTGAT
CTGGCGGAGATATCAGATCTGGTGATTGCAAAAGGCATCAACCCACAGCCCCGCTCAGGACGGCAGGAGCGGCTGGAAAA
TCTGGTGAACAAATACCTTTAA

Upstream 100 bases:

>100_bases
CTCCCGCAGCGTTGACCCTGATCCTGCCCTGCACGCTGCCATGGCCGATGCGCATGCGCGGTATAATCATGCCTATACAC
TTCTGAAGGACCTTTGACTC

Downstream 100 bases:

>100_bases
AACAGCGCTGTCGTTTTCAAAAAGCGACATGCCCGGAAATCCCGGCATCCGGCGCTCAGTAACCTGAAGGCGCTCCGACA
GGTATGCGACCCGCCAGCGA

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTDFFKDIPAIRYEGPDTENEFAFRHYNPDEVVMGKTLKDHLRFACAYWHSFAWPGGDPFGGQTFERPWFGDTMELAKLK
ADVAFDMFERLGVPYFCFHDADVRPEGDTFAESTKNLEEITDYFAEKMDATGVKLLWGTANLFSHRRFMAGAATNPDPEV
FAYSAATIKSCMDATRKLGGENYVLWGGREGYETLLNTDMARERAQAGRMLQMVVDYKHKTGFAGTILIEPKPQEPTKHQ
YDYDVATVYGFLKDFGLEGEVKVNIEQGHAILAGHSFEHELALARALGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAY
YEVLRAGGFDTGGTNFDAKLRRQSLDPADLILAHVGGMDACAAGLKAAAAMLEDGKLEAAREARYAGWSEGLGQKLLTSD
LAEISDLVIAKGINPQPRSGRQERLENLVNKYL

Sequences:

>Translated_433_residues
MTDFFKDIPAIRYEGPDTENEFAFRHYNPDEVVMGKTLKDHLRFACAYWHSFAWPGGDPFGGQTFERPWFGDTMELAKLK
ADVAFDMFERLGVPYFCFHDADVRPEGDTFAESTKNLEEITDYFAEKMDATGVKLLWGTANLFSHRRFMAGAATNPDPEV
FAYSAATIKSCMDATRKLGGENYVLWGGREGYETLLNTDMARERAQAGRMLQMVVDYKHKTGFAGTILIEPKPQEPTKHQ
YDYDVATVYGFLKDFGLEGEVKVNIEQGHAILAGHSFEHELALARALGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAY
YEVLRAGGFDTGGTNFDAKLRRQSLDPADLILAHVGGMDACAAGLKAAAAMLEDGKLEAAREARYAGWSEGLGQKLLTSD
LAEISDLVIAKGINPQPRSGRQERLENLVNKYL
>Mature_432_residues
TDFFKDIPAIRYEGPDTENEFAFRHYNPDEVVMGKTLKDHLRFACAYWHSFAWPGGDPFGGQTFERPWFGDTMELAKLKA
DVAFDMFERLGVPYFCFHDADVRPEGDTFAESTKNLEEITDYFAEKMDATGVKLLWGTANLFSHRRFMAGAATNPDPEVF
AYSAATIKSCMDATRKLGGENYVLWGGREGYETLLNTDMARERAQAGRMLQMVVDYKHKTGFAGTILIEPKPQEPTKHQY
DYDVATVYGFLKDFGLEGEVKVNIEQGHAILAGHSFEHELALARALGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAYY
EVLRAGGFDTGGTNFDAKLRRQSLDPADLILAHVGGMDACAAGLKAAAAMLEDGKLEAAREARYAGWSEGLGQKLLTSDL
AEISDLVIAKGINPQPRSGRQERLENLVNKYL

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=437, Percent_Identity=59.954233409611, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_ROSDO (Q162B6)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683863.1
- ProteinModelPortal:   Q162B6
- SMR:   Q162B6
- STRING:   Q162B6
- GeneID:   4196123
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3705
- NMPDR:   fig|375451.6.peg.3445
- eggNOG:   COG2115
- HOGENOM:   HBG297199
- OMA:   VWESAKS
- PhylomeDB:   Q162B6
- ProtClustDB:   PRK05474
- BioCyc:   RDEN375451:RD1_3705-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 48310; Mature: 48179

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 99-99 ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFFKDIPAIRYEGPDTENEFAFRHYNPDEVVMGKTLKDHLRFACAYWHSFAWPGGDPF
CCCHHHHCCCEEECCCCCCCCEEEEECCCCHHEECHHHHHHHHHHHHHHHHCCCCCCCCC
GGQTFERPWFGDTMELAKLKADVAFDMFERLGVPYFCFHDADVRPEGDTFAESTKNLEEI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
TDYFAEKMDATGVKLLWGTANLFSHRRFMAGAATNPDPEVFAYSAATIKSCMDATRKLGG
HHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCC
ENYVLWGGREGYETLLNTDMARERAQAGRMLQMVVDYKHKTGFAGTILIEPKPQEPTKHQ
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
YDYDVATVYGFLKDFGLEGEVKVNIEQGHAILAGHSFEHELALARALGIFGSIDMNRNDY
CCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCC
QSGWDTDQFPNNVPEMALAYYEVLRAGGFDTGGTNFDAKLRRQSLDPADLILAHVGGMDA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCHHH
CAAGLKAAAAMLEDGKLEAAREARYAGWSEGLGQKLLTSDLAEISDLVIAKGINPQPRSG
HHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RQERLENLVNKYL
HHHHHHHHHHHCC
>Mature Secondary Structure 
TDFFKDIPAIRYEGPDTENEFAFRHYNPDEVVMGKTLKDHLRFACAYWHSFAWPGGDPF
CCHHHHCCCEEECCCCCCCCEEEEECCCCHHEECHHHHHHHHHHHHHHHHCCCCCCCCC
GGQTFERPWFGDTMELAKLKADVAFDMFERLGVPYFCFHDADVRPEGDTFAESTKNLEEI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
TDYFAEKMDATGVKLLWGTANLFSHRRFMAGAATNPDPEVFAYSAATIKSCMDATRKLGG
HHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCC
ENYVLWGGREGYETLLNTDMARERAQAGRMLQMVVDYKHKTGFAGTILIEPKPQEPTKHQ
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
YDYDVATVYGFLKDFGLEGEVKVNIEQGHAILAGHSFEHELALARALGIFGSIDMNRNDY
CCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCC
QSGWDTDQFPNNVPEMALAYYEVLRAGGFDTGGTNFDAKLRRQSLDPADLILAHVGGMDA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCHHH
CAAGLKAAAAMLEDGKLEAAREARYAGWSEGLGQKLLTSDLAEISDLVIAKGINPQPRSG
HHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RQERLENLVNKYL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA