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The map label for this gene is xylB [H]

Identifier: 110680855

GI number: 110680855

Start: 3573593

End: 3575029

Strand: Direct

Name: xylB [H]

Synonym: RD1_3704

Alternate gene names: 110680855

Gene position: 3573593-3575029 (Clockwise)

Preceding gene: 110680854

Following gene: 110680856

Centisome position: 86.46

GC content: 63.54

Gene sequence:

>1437_bases
GTGACATTCATTGGCCTGGACCTCGGCACCTCATCGCTCAAGGCGATCCTGATGGACGCACAACAGAACATCCTGTCCGA
ACATGCTGTTCCCCTGAGCGTGGAGCGCCGGCAGGACGGATGGTCCGAACAGGACCCGCAAAGTTGGTGCGATGCTGCCA
TCGAAGCACTGAGCGCTTTGGCAGCACACCCGGCCTGCGGCGAGGTTATGGGTATTGGCCTGTCGGGCCATATGCATGGC
GCAACGTTGATCGGGGCAGATGATGCGCCGCTGCGGCCCTGTATGCTTTGGAACGACACGCGCAGCCACGTCGAGGCCGC
AGGCATGGACGCCGATCCGCAATTTCGCGATATCAGTGGCAATATCGTCTTTCCCGGATTTACTGCACCCAAGGTCGAAT
GGGTCCGCCGAAACGAGCCGCATGTCTTCGATCAGACCGCCAAAGTCCTGCTGCCCAAGGACTACCTGCGCCGGTTCCTG
ACCGGTGAATATTTCTCGGAGATGTCGGATGCGGCGGGCACCGCGTGGTTTGACACCGGGAAACGGGACTGGTCGGATGC
GCTGCTTTCTGAATGCGGCCTGACGCGCGCGCAGATGCCCGCGCTGGTCGAGGGGTCGACCCCATCTGGCACATTGCGCA
AGGATCTTGCCGCGCAGACGGGTGTCCCGCAATGCACCGTCGCGGGCGGGGCCGGTGACAACGCCGCCGCCGCGATCGGC
GCGGGCGTTGTCACGGAAGGCTCTGCGTTTTTGTCGCTGGGCACGTCGGGGGTTCTTTTTGCCGCGAACGCGGGCTACCG
CCCTGCCCCTTCCTCTGCTGTGCACACATTTTGTCATGCGCTGCCCGACACGTGGCACCAGATGGGCGTGATCCTCGCGG
CAACTGACGCTTTGGAATGGCTTGCCCGGCTCACGGGTCAGAGTGCGGCGGCCTTGACCCGCGACCTTGGCGTCGTGCGC
GCGCCCGAAAAGACGCTGTTTCTGCCCTATCTGGGCGGGGAGCGGACACCGCATAACGACGCGCAAATCCGTGGACAGTT
CCTGCATCTTGATCATGCGACAGACGCCAAGGCCGCCGCCCGCGCCGTTTTGCAGGGTGTCAGCTTTGCCTTTGCCGATT
GCAAGGACGCGCTGAGCGCCACGGGCACGAAAGTCACACGCGCGCTGGCGCTTGGCGGGGGGGCCAAATCCGATCACTGG
GTCGCGATGCTGGCCACGACATTGAACATCACGCTCGATGTCCCCAGGGACGGTGATTTCGGCGCAGCACTGGGCGCTGC
GCGATTGGCGATGATGGCCAGCACAGGCGGGGGCGCGGACATTGCATCGCAGCCGCCCATCTCCCGCAGCGTTGACCCTG
ATCCTGCCCTGCACGCTGCCATGGCCGATGCGCATGCGCGGTATAATCATGCCTATACACTTCTGAAGGACCTTTGA

Upstream 100 bases:

>100_bases
TACCCGACAGTGATGGATGGGTTGCGCGGTGTCGAGTTTGTCGACGCCTGCGTGCGGTCGTCCGCGCGCAATGCGGCCTG
GGTCAAGCTGAGGTAGCACC

Downstream 100 bases:

>100_bases
CTCATGACCGATTTCTTCAAGGACATCCCCGCCATCCGCTATGAGGGACCCGATACCGAGAACGAATTTGCGTTCCGGCA
CTATAATCCGGATGAGGTCG

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTFIGLDLGTSSLKAILMDAQQNILSEHAVPLSVERRQDGWSEQDPQSWCDAAIEALSALAAHPACGEVMGIGLSGHMHG
ATLIGADDAPLRPCMLWNDTRSHVEAAGMDADPQFRDISGNIVFPGFTAPKVEWVRRNEPHVFDQTAKVLLPKDYLRRFL
TGEYFSEMSDAAGTAWFDTGKRDWSDALLSECGLTRAQMPALVEGSTPSGTLRKDLAAQTGVPQCTVAGGAGDNAAAAIG
AGVVTEGSAFLSLGTSGVLFAANAGYRPAPSSAVHTFCHALPDTWHQMGVILAATDALEWLARLTGQSAAALTRDLGVVR
APEKTLFLPYLGGERTPHNDAQIRGQFLHLDHATDAKAAARAVLQGVSFAFADCKDALSATGTKVTRALALGGGAKSDHW
VAMLATTLNITLDVPRDGDFGAALGAARLAMMASTGGGADIASQPPISRSVDPDPALHAAMADAHARYNHAYTLLKDL

Sequences:

>Translated_478_residues
MTFIGLDLGTSSLKAILMDAQQNILSEHAVPLSVERRQDGWSEQDPQSWCDAAIEALSALAAHPACGEVMGIGLSGHMHG
ATLIGADDAPLRPCMLWNDTRSHVEAAGMDADPQFRDISGNIVFPGFTAPKVEWVRRNEPHVFDQTAKVLLPKDYLRRFL
TGEYFSEMSDAAGTAWFDTGKRDWSDALLSECGLTRAQMPALVEGSTPSGTLRKDLAAQTGVPQCTVAGGAGDNAAAAIG
AGVVTEGSAFLSLGTSGVLFAANAGYRPAPSSAVHTFCHALPDTWHQMGVILAATDALEWLARLTGQSAAALTRDLGVVR
APEKTLFLPYLGGERTPHNDAQIRGQFLHLDHATDAKAAARAVLQGVSFAFADCKDALSATGTKVTRALALGGGAKSDHW
VAMLATTLNITLDVPRDGDFGAALGAARLAMMASTGGGADIASQPPISRSVDPDPALHAAMADAHARYNHAYTLLKDL
>Mature_477_residues
TFIGLDLGTSSLKAILMDAQQNILSEHAVPLSVERRQDGWSEQDPQSWCDAAIEALSALAAHPACGEVMGIGLSGHMHGA
TLIGADDAPLRPCMLWNDTRSHVEAAGMDADPQFRDISGNIVFPGFTAPKVEWVRRNEPHVFDQTAKVLLPKDYLRRFLT
GEYFSEMSDAAGTAWFDTGKRDWSDALLSECGLTRAQMPALVEGSTPSGTLRKDLAAQTGVPQCTVAGGAGDNAAAAIGA
GVVTEGSAFLSLGTSGVLFAANAGYRPAPSSAVHTFCHALPDTWHQMGVILAATDALEWLARLTGQSAAALTRDLGVVRA
PEKTLFLPYLGGERTPHNDAQIRGQFLHLDHATDAKAAARAVLQGVSFAFADCKDALSATGTKVTRALALGGGAKSDHWV
AMLATTLNITLDVPRDGDFGAALGAARLAMMASTGGGADIASQPPISRSVDPDPALHAAMADAHARYNHAYTLLKDL

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI189409120, Length=439, Percent_Identity=22.7790432801822, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4504007, Length=439, Percent_Identity=22.7790432801822, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI42794763, Length=440, Percent_Identity=22.0454545454545, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI41393575, Length=442, Percent_Identity=21.9457013574661, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI18860918, Length=514, Percent_Identity=22.3735408560311, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1789987, Length=485, Percent_Identity=46.5979381443299, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1790005, Length=490, Percent_Identity=24.6938775510204, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790361, Length=458, Percent_Identity=23.7991266375546, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789168, Length=444, Percent_Identity=23.4234234234234, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17535599, Length=422, Percent_Identity=25.5924170616114, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI17864214, Length=510, Percent_Identity=22.9411764705882, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24655555, Length=433, Percent_Identity=23.7875288683603, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24655560, Length=433, Percent_Identity=23.7875288683603, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24655570, Length=433, Percent_Identity=23.7875288683603, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24655574, Length=433, Percent_Identity=23.7875288683603, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24655565, Length=433, Percent_Identity=23.7875288683603, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 50217; Mature: 50086

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00933 FGGY_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFIGLDLGTSSLKAILMDAQQNILSEHAVPLSVERRQDGWSEQDPQSWCDAAIEALSAL
CEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCHHHHHHHHHHHHHHH
AAHPACGEVMGIGLSGHMHGATLIGADDAPLRPCMLWNDTRSHVEAAGMDADPQFRDISG
HCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCEEEECCHHHHHHHCCCCCCCCCEECCC
NIVFPGFTAPKVEWVRRNEPHVFDQTAKVLLPKDYLRRFLTGEYFSEMSDAAGTAWFDTG
CEEECCCCCCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCC
KRDWSDALLSECGLTRAQMPALVEGSTPSGTLRKDLAAQTGVPQCTVAGGAGDNAAAAIG
CCCHHHHHHHHHCCCHHHCCEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHC
AGVVTEGSAFLSLGTSGVLFAANAGYRPAPSSAVHTFCHALPDTWHQMGVILAATDALEW
CCEEECCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCEEEEHHHHHHH
LARLTGQSAAALTRDLGVVRAPEKTLFLPYLGGERTPHNDAQIRGQFLHLDHATDAKAAA
HHHHCCCHHHHHHHHCCCEECCCCEEEEEECCCCCCCCCCHHEEEEEEEECCCCCHHHHH
RAVLQGVSFAFADCKDALSATGTKVTRALALGGGAKSDHWVAMLATTLNITLDVPRDGDF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCCC
GAALGAARLAMMASTGGGADIASQPPISRSVDPDPALHAAMADAHARYNHAYTLLKDL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFIGLDLGTSSLKAILMDAQQNILSEHAVPLSVERRQDGWSEQDPQSWCDAAIEALSAL
EEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCHHHHHHHHHHHHHHH
AAHPACGEVMGIGLSGHMHGATLIGADDAPLRPCMLWNDTRSHVEAAGMDADPQFRDISG
HCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCEEEECCHHHHHHHCCCCCCCCCEECCC
NIVFPGFTAPKVEWVRRNEPHVFDQTAKVLLPKDYLRRFLTGEYFSEMSDAAGTAWFDTG
CEEECCCCCCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCC
KRDWSDALLSECGLTRAQMPALVEGSTPSGTLRKDLAAQTGVPQCTVAGGAGDNAAAAIG
CCCHHHHHHHHHCCCHHHCCEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHC
AGVVTEGSAFLSLGTSGVLFAANAGYRPAPSSAVHTFCHALPDTWHQMGVILAATDALEW
CCEEECCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCEEEEHHHHHHH
LARLTGQSAAALTRDLGVVRAPEKTLFLPYLGGERTPHNDAQIRGQFLHLDHATDAKAAA
HHHHCCCHHHHHHHHCCCEECCCCEEEEEECCCCCCCCCCHHEEEEEEEECCCCCHHHHH
RAVLQGVSFAFADCKDALSATGTKVTRALALGGGAKSDHWVAMLATTLNITLDVPRDGDF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCCC
GAALGAARLAMMASTGGGADIASQPPISRSVDPDPALHAAMADAHARYNHAYTLLKDL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]