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The map label for this gene is livM [H]

Identifier: 110680748

GI number: 110680748

Start: 3452112

End: 3453140

Strand: Direct

Name: livM [H]

Synonym: RD1_3590

Alternate gene names: 110680748

Gene position: 3452112-3453140 (Clockwise)

Preceding gene: 110680747

Following gene: 110680749

Centisome position: 83.52

GC content: 59.67

Gene sequence:

>1029_bases
ATGGCCCAGACACATAAACAAAAGCGTCTCAGCGCATGGTCAACGCCGATCCTGCTGATAGCCATTCTGGCGGTGTTCAC
TCTACTGGTCACGTTGCTGGGCGATAATTCACTTGCCCGCATGGCGGCGCAGACCCTGATCCGTGTCACCTTTGTCGTGG
GGCTGTGGATTTTCGTCGGCAACTCCGGCATCGTCAGTTTTGGCCATGCAGGCTATATGGCCGTCGGGGCCTATTGCTCT
GCGTGGTTGACACTCAGACCGCAGATGAAGGGGATGTTCCTGCCCGACCTGTGGCCATTTCTGGCCACGGCAGAATGGTC
GGTATTTCCAGCGGCAGTTGTGTCCGGCCTGCTCGCAGCCTTTATCGCGCTGCTCTCCGGTGCTGCCATTCTGCGGCTGT
CAGGCATCGCTGCGTCCATCGCAACATTCGCCTTTCTTGCGATTGTCTACACGGTCTATTCCAGTTGGGAGGGCGTGACC
GGGGCGACATCCTCTGTCGTTGGCCTGACGCGATACGCAGATCAATGGGTCACGCTTGGCTGGGCCAGCGCGACTATTCT
GGCCGCGGCGTGGTACGCAAACTCCGCCTCTGGCCTTGCGCTGCGCGCCAGCCGGGAAGACGAGGTTGCCGCAGATGCAA
GTGGCATCAACATGTACCGCCACCGCCTGATCGCGCTTGTGGTCTCTGCCTTCTTTGCAGGTGTGGCCGGGGCATTATTC
GGCCACTCCTTGGGCGTTCTGAACCCCAACAGCTTTTATCTTGGCGTCACCTTCATCACGCTCGCCATGCTGGTCGTAGG
TGGGATTGGCAGCCTGACGGGCGCTGTCATGGGCGTGCTTGTTCTTTCGATCATCATCGAAGCCCTCGTGCGCATGGAAC
GCGGCATGGAGATCGGTGAAGCGACATTCGCACTGCCGACAGGCGCTCAGGAAATCATCATCGGGGTCATCATGATCCTT
GTTCTCATTCTGCGTCCCACCGGGCTGACAGGGGGGCGTGAACTCCGTCTGCGGATCGGTGGTCGCTGA

Upstream 100 bases:

>100_bases
GTTTCGCGATGCGTTTCTCTACACGCTCGTGATTGTCAGCCTGCTGCTGAAACCCGACGGCCTCTTTGCGCCCCGATCCA
CCAAGCCGAGAGTGTAACCC

Downstream 100 bases:

>100_bases
CGGGGAAACAACAACACCAACACTCAACGGGAGAAGACATATGAAACACCTTTTGACGGCCACGACACTGGCACTCAGCC
TTGGCACAACGGCGATCGCA

Product: branched-chain amino acid ABC transporter, permease protein, putative

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAQTHKQKRLSAWSTPILLIAILAVFTLLVTLLGDNSLARMAAQTLIRVTFVVGLWIFVGNSGIVSFGHAGYMAVGAYCS
AWLTLRPQMKGMFLPDLWPFLATAEWSVFPAAVVSGLLAAFIALLSGAAILRLSGIAASIATFAFLAIVYTVYSSWEGVT
GATSSVVGLTRYADQWVTLGWASATILAAAWYANSASGLALRASREDEVAADASGINMYRHRLIALVVSAFFAGVAGALF
GHSLGVLNPNSFYLGVTFITLAMLVVGGIGSLTGAVMGVLVLSIIIEALVRMERGMEIGEATFALPTGAQEIIIGVIMIL
VLILRPTGLTGGRELRLRIGGR

Sequences:

>Translated_342_residues
MAQTHKQKRLSAWSTPILLIAILAVFTLLVTLLGDNSLARMAAQTLIRVTFVVGLWIFVGNSGIVSFGHAGYMAVGAYCS
AWLTLRPQMKGMFLPDLWPFLATAEWSVFPAAVVSGLLAAFIALLSGAAILRLSGIAASIATFAFLAIVYTVYSSWEGVT
GATSSVVGLTRYADQWVTLGWASATILAAAWYANSASGLALRASREDEVAADASGINMYRHRLIALVVSAFFAGVAGALF
GHSLGVLNPNSFYLGVTFITLAMLVVGGIGSLTGAVMGVLVLSIIIEALVRMERGMEIGEATFALPTGAQEIIIGVIMIL
VLILRPTGLTGGRELRLRIGGR
>Mature_341_residues
AQTHKQKRLSAWSTPILLIAILAVFTLLVTLLGDNSLARMAAQTLIRVTFVVGLWIFVGNSGIVSFGHAGYMAVGAYCSA
WLTLRPQMKGMFLPDLWPFLATAEWSVFPAAVVSGLLAAFIALLSGAAILRLSGIAASIATFAFLAIVYTVYSSWEGVTG
ATSSVVGLTRYADQWVTLGWASATILAAAWYANSASGLALRASREDEVAADASGINMYRHRLIALVVSAFFAGVAGALFG
HSLGVLNPNSFYLGVTFITLAMLVVGGIGSLTGAVMGVLVLSIIIEALVRMERGMEIGEATFALPTGAQEIIIGVIMILV
LILRPTGLTGGRELRLRIGGR

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=323, Percent_Identity=26.0061919504644, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 36042; Mature: 35911

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTHKQKRLSAWSTPILLIAILAVFTLLVTLLGDNSLARMAAQTLIRVTFVVGLWIFVG
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
NSGIVSFGHAGYMAVGAYCSAWLTLRPQMKGMFLPDLWPFLATAEWSVFPAAVVSGLLAA
CCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
FIALLSGAAILRLSGIAASIATFAFLAIVYTVYSSWEGVTGATSSVVGLTRYADQWVTLG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
WASATILAAAWYANSASGLALRASREDEVAADASGINMYRHRLIALVVSAFFAGVAGALF
HHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHSLGVLNPNSFYLGVTFITLAMLVVGGIGSLTGAVMGVLVLSIIIEALVRMERGMEIGE
HCCCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ATFALPTGAQEIIIGVIMILVLILRPTGLTGGRELRLRIGGR
CEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
AQTHKQKRLSAWSTPILLIAILAVFTLLVTLLGDNSLARMAAQTLIRVTFVVGLWIFVG
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
NSGIVSFGHAGYMAVGAYCSAWLTLRPQMKGMFLPDLWPFLATAEWSVFPAAVVSGLLAA
CCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
FIALLSGAAILRLSGIAASIATFAFLAIVYTVYSSWEGVTGATSSVVGLTRYADQWVTLG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
WASATILAAAWYANSASGLALRASREDEVAADASGINMYRHRLIALVVSAFFAGVAGALF
HHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHSLGVLNPNSFYLGVTFITLAMLVVGGIGSLTGAVMGVLVLSIIIEALVRMERGMEIGE
HCCCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ATFALPTGAQEIIIGVIMILVLILRPTGLTGGRELRLRIGGR
CEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]