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The map label for this gene is yiaV [H]

Identifier: 110680648

GI number: 110680648

Start: 3352578

End: 3353813

Strand: Direct

Name: yiaV [H]

Synonym: RD1_3484

Alternate gene names: 110680648

Gene position: 3352578-3353813 (Clockwise)

Preceding gene: 110680647

Following gene: 110680652

Centisome position: 81.12

GC content: 59.06

Gene sequence:

>1236_bases
ATGCTTGAGACACTGATCTGCGCGCTGTTTACGATCCTACCTGACTATCTCTATCGCCGCTTCCGGCAGGGCAAGAGAAT
AGGTATTGAAATCAACCTTTTCAGCGTCTGGTATGAACTCAGGTGGGGCATAACCGGATGCGCGATCATGGCGCTCACCG
TGATTACCACGCTGTTTTATTTCCACCCGGCCACAAATTCCGTCGTGTCCTATTTTCGCACAGTGACGATCTTGCCGCAG
GCCGGGGGCCGCGTGCTGGAAATCTACGTCAAGAACAACGAATTGGTGAACCTGGGCCAGCCGATATTTCGTCTGGAGGA
CCACTCCCAACGCGCACAGGTCGAAGCCGCAAAGGCGATGATTGCGCAGGCCGATGCCTCCCTGAAAGTCGCGCAAACCG
ATCTGACCGAGGCCACCGCCGCCATCGCCGGGGCCACCGCTGCCCTGAAGCAGGCGGAGGAAGAGCTCGAACGCAATGTG
ACCCTGCGCGATCAGGGCTCGACCGCCGTGCGCCTTACTGAAATCGACCGTTTTGAAAACCTCGTTGCGCAACGCTCCGC
ACAGCGTGACGCAGCGATTGCCCAACTGGCGGAGACGCAGGAACGCATCGATTCGCTCATCCCCGCGCAGAAAGCCAACG
CGCTCGCACAGTTTGATGCAGCCAATGCCGAGCTGGAAAAAACCGTGGTCTATGCGGGCGTGACCGGTCGTGTCGAACAA
CTGAGCCTGCAGGTCGGTGACTACATCAGCCCGGTCCTGCGACCAGCGGGCGTTCTGGTGCCCGTGACATCCGGGCGGAG
CCGCTTTCAGGCCGGTTTCAACCAAATGGCCGCACAGGTCATCAAACCGGGAATGATTGGCGAAATCGGTTGTATGACCA
AGCCGTTTACCGTCATTCCGATGGTGGTTGTCGCGGTTCAGGACGTGATCCCGTCGGGACAGGTCCGCCCCAGCGACCGC
CTGCTGGACCCGCAGAACAACCAGCAGCCGGGCAGCGTCATGGTCTATCTGGAACCGCTTTACGAAGGGACGGCCGAACT
ATTGCCGCCGGGCAGCAACTGCATCGCGAACGTCTACACGGACAATCACGAACGCCTTGAGGACGAAAGCCTCGGCACTC
TTCACAAGCTGGCACTACATGTGATTGACACGATCGGCGTGGTCCATGCGGCTGGTTTGAGACTGAGACTATTGCTGATG
CCGGTGCAGACGCTAGTGTTCAGCGGCGGTCATTGA

Upstream 100 bases:

>100_bases
CCCCTGCGCGCCATTGCCGATGCGATTGATCGAAACGGGTCGCATGACACACCCGCCGCTGCGCAAACCCCGATCAATCC
GGCGCCGAAAGACACCTCCG

Downstream 100 bases:

>100_bases
TCCAGAGCGTGTGACGAAAAACCTGAAAAATCACGCATCACGCAACGCGTTGAAATCCTTTATTTCAGGCAGCGTTACGT
GATCTACGTTTTTCGCATGA

Product: multidrug resistance efflux pump, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLETLICALFTILPDYLYRRFRQGKRIGIEINLFSVWYELRWGITGCAIMALTVITTLFYFHPATNSVVSYFRTVTILPQ
AGGRVLEIYVKNNELVNLGQPIFRLEDHSQRAQVEAAKAMIAQADASLKVAQTDLTEATAAIAGATAALKQAEEELERNV
TLRDQGSTAVRLTEIDRFENLVAQRSAQRDAAIAQLAETQERIDSLIPAQKANALAQFDAANAELEKTVVYAGVTGRVEQ
LSLQVGDYISPVLRPAGVLVPVTSGRSRFQAGFNQMAAQVIKPGMIGEIGCMTKPFTVIPMVVVAVQDVIPSGQVRPSDR
LLDPQNNQQPGSVMVYLEPLYEGTAELLPPGSNCIANVYTDNHERLEDESLGTLHKLALHVIDTIGVVHAAGLRLRLLLM
PVQTLVFSGGH

Sequences:

>Translated_411_residues
MLETLICALFTILPDYLYRRFRQGKRIGIEINLFSVWYELRWGITGCAIMALTVITTLFYFHPATNSVVSYFRTVTILPQ
AGGRVLEIYVKNNELVNLGQPIFRLEDHSQRAQVEAAKAMIAQADASLKVAQTDLTEATAAIAGATAALKQAEEELERNV
TLRDQGSTAVRLTEIDRFENLVAQRSAQRDAAIAQLAETQERIDSLIPAQKANALAQFDAANAELEKTVVYAGVTGRVEQ
LSLQVGDYISPVLRPAGVLVPVTSGRSRFQAGFNQMAAQVIKPGMIGEIGCMTKPFTVIPMVVVAVQDVIPSGQVRPSDR
LLDPQNNQQPGSVMVYLEPLYEGTAELLPPGSNCIANVYTDNHERLEDESLGTLHKLALHVIDTIGVVHAAGLRLRLLLM
PVQTLVFSGGH
>Mature_411_residues
MLETLICALFTILPDYLYRRFRQGKRIGIEINLFSVWYELRWGITGCAIMALTVITTLFYFHPATNSVVSYFRTVTILPQ
AGGRVLEIYVKNNELVNLGQPIFRLEDHSQRAQVEAAKAMIAQADASLKVAQTDLTEATAAIAGATAALKQAEEELERNV
TLRDQGSTAVRLTEIDRFENLVAQRSAQRDAAIAQLAETQERIDSLIPAQKANALAQFDAANAELEKTVVYAGVTGRVEQ
LSLQVGDYISPVLRPAGVLVPVTSGRSRFQAGFNQMAAQVIKPGMIGEIGCMTKPFTVIPMVVVAVQDVIPSGQVRPSDR
LLDPQNNQQPGSVMVYLEPLYEGTAELLPPGSNCIANVYTDNHERLEDESLGTLHKLALHVIDTIGVVHAAGLRLRLLLM
PVQTLVFSGGH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=338, Percent_Identity=26.6272189349112, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790024, Length=282, Percent_Identity=25.886524822695, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790519, Length=210, Percent_Identity=29.5238095238095, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44947; Mature: 44947

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETLICALFTILPDYLYRRFRQGKRIGIEINLFSVWYELRWGITGCAIMALTVITTLFY
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FHPATNSVVSYFRTVTILPQAGGRVLEIYVKNNELVNLGQPIFRLEDHSQRAQVEAAKAM
HCCCHHHHHHHHHHHEEEECCCCEEEEEEEECCCEEECCCCCEEECCCHHHHHHHHHHHH
IAQADASLKVAQTDLTEATAAIAGATAALKQAEEELERNVTLRDQGSTAVRLTEIDRFEN
HHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHHHHH
LVAQRSAQRDAAIAQLAETQERIDSLIPAQKANALAQFDAANAELEKTVVYAGVTGRVEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHEEEEECCCCCHHH
LSLQVGDYISPVLRPAGVLVPVTSGRSRFQAGFNQMAAQVIKPGMIGEIGCMTKPFTVIP
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
MVVVAVQDVIPSGQVRPSDRLLDPQNNQQPGSVMVYLEPLYEGTAELLPPGSNCIANVYT
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHCCHHHHCCCCCCCEEEEEC
DNHERLEDESLGTLHKLALHVIDTIGVVHAAGLRLRLLLMPVQTLVFSGGH
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLETLICALFTILPDYLYRRFRQGKRIGIEINLFSVWYELRWGITGCAIMALTVITTLFY
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FHPATNSVVSYFRTVTILPQAGGRVLEIYVKNNELVNLGQPIFRLEDHSQRAQVEAAKAM
HCCCHHHHHHHHHHHEEEECCCCEEEEEEEECCCEEECCCCCEEECCCHHHHHHHHHHHH
IAQADASLKVAQTDLTEATAAIAGATAALKQAEEELERNVTLRDQGSTAVRLTEIDRFEN
HHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHHHHH
LVAQRSAQRDAAIAQLAETQERIDSLIPAQKANALAQFDAANAELEKTVVYAGVTGRVEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHEEEEECCCCCHHH
LSLQVGDYISPVLRPAGVLVPVTSGRSRFQAGFNQMAAQVIKPGMIGEIGCMTKPFTVIP
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
MVVVAVQDVIPSGQVRPSDRLLDPQNNQQPGSVMVYLEPLYEGTAELLPPGSNCIANVYT
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHCCHHHHCCCCCCCEEEEEC
DNHERLEDESLGTLHKLALHVIDTIGVVHAAGLRLRLLLMPVQTLVFSGGH
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]