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The map label for this gene is dacC [H]

Identifier: 110680629

GI number: 110680629

Start: 3335314

End: 3336483

Strand: Direct

Name: dacC [H]

Synonym: RD1_3465

Alternate gene names: 110680629

Gene position: 3335314-3336483 (Clockwise)

Preceding gene: 110680628

Following gene: 110680630

Centisome position: 80.7

GC content: 60.43

Gene sequence:

>1170_bases
ATGTTTCGTATCCTTCTTGCCGCTTTTGTTCTGGTTGCATCGACACTGACCGCAGCGGCCTTTGAAACCAGAGCCAGTGC
TGCTTTTGTAATGGATCAGACCACCGGCACCGTGCTGCTCAATAAAAACGCCGACGCGCCCTTGCCGCCGGCCTCCATGT
CCAAACTGATGACGCTTTACATGGCATTCGAAGCCGTGCGGCGCGGCAAGGCCGACGGCGGGCTGGACCTAAATGAACGC
TTGCCCGTGTCCGAACATGCGCAGTCCTACGGCGGCTCCAGCATGTTCTTGCGCTCCGGCGAGACGGTCAGTGTCGAGGA
TTTGCTGCGCGGCATCATCGTCGTGTCAGGCAACGATGCCTGTGTGGTCATCGCCGAAGCGCTTTCGCCTGATGGAACGG
AATACGGCTTTGCGCGCATGATGACACAGCGCGCGCAACAGCTTGGTATGAACAACTCCGTTTTCATCAACGCCAGCGGA
TGGCCGCAAACCGGGCATGTGATGTCGATGCGCGATCTTGCCATTCTGGCTGACCGGCTGATCACCGATTTCCCAGAATT
CTACCCGATGTTTGCGGAGACCGAATTCCCCTTCGACAACCGTGTGCCCAGCAACAGCCGCAACCGCAACCCGGTGCTGA
CCATGGGTATTGGCGCGGACGGGTTGAAAACCGGCCACACGCAAGAGGCCGGATACGGTCTTGTCGGCTCGGCCAAGCAA
GGTGATCGGCGGATCATCTTTGTCATCACCGGGTTGGAGACGACAGCGGCGCGCGCGCAGGAAAGCCAGGCCATCGTGAA
CTGGGCCTTCAGACAATTCGCCATGCGCGACATTGGCAAGGCAGGTCAGGAATTTGCCAAGGCGGACGTCTGGATGGGCA
GCAGCCCGCAGGTCGGGCTGGTCGCAGCCGAGGACATGAGCGTGTTGATGCCCGCCCTTGCGGAGCGTGAAATCGAGGCC
GAGGTGGTGTTTACCGGCCCGATCGAGGCACCAATCGCCAAAGGGGACCCGCTGGGAGAGCTCGTGTTCACTCCTGAGGG
TCTGCCGGAAATGCGCCTGCCGCTGGTGGCGGATCAAGACGTGCCGAGTGGCGGTTTTGTCACCCGCATGATGACGGCAG
CCATGGTTCTGGTCACGACGCTGATACAGGGGCCAGAGGAACAGTCGTGA

Upstream 100 bases:

>100_bases
GTTCGATATCCGAGCGCGAAAAACTGCTCGCGCAAACCAAGGCAGAAGGCTATTCAGACGCCTATGTCGTGACAAACTGA
CCCGTCAGCGAGGAAAAAAC

Downstream 100 bases:

>100_bases
TATCGCGCACCCGCGACACCGGGTTTTTCATCACCTTTGAGGGCATTGACGGGTCGGGCAAATCCACCCAATCCAAAAGG
CTTGCCGCCCATTTGCGCGC

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MFRILLAAFVLVASTLTAAAFETRASAAFVMDQTTGTVLLNKNADAPLPPASMSKLMTLYMAFEAVRRGKADGGLDLNER
LPVSEHAQSYGGSSMFLRSGETVSVEDLLRGIIVVSGNDACVVIAEALSPDGTEYGFARMMTQRAQQLGMNNSVFINASG
WPQTGHVMSMRDLAILADRLITDFPEFYPMFAETEFPFDNRVPSNSRNRNPVLTMGIGADGLKTGHTQEAGYGLVGSAKQ
GDRRIIFVITGLETTAARAQESQAIVNWAFRQFAMRDIGKAGQEFAKADVWMGSSPQVGLVAAEDMSVLMPALAEREIEA
EVVFTGPIEAPIAKGDPLGELVFTPEGLPEMRLPLVADQDVPSGGFVTRMMTAAMVLVTTLIQGPEEQS

Sequences:

>Translated_389_residues
MFRILLAAFVLVASTLTAAAFETRASAAFVMDQTTGTVLLNKNADAPLPPASMSKLMTLYMAFEAVRRGKADGGLDLNER
LPVSEHAQSYGGSSMFLRSGETVSVEDLLRGIIVVSGNDACVVIAEALSPDGTEYGFARMMTQRAQQLGMNNSVFINASG
WPQTGHVMSMRDLAILADRLITDFPEFYPMFAETEFPFDNRVPSNSRNRNPVLTMGIGADGLKTGHTQEAGYGLVGSAKQ
GDRRIIFVITGLETTAARAQESQAIVNWAFRQFAMRDIGKAGQEFAKADVWMGSSPQVGLVAAEDMSVLMPALAEREIEA
EVVFTGPIEAPIAKGDPLGELVFTPEGLPEMRLPLVADQDVPSGGFVTRMMTAAMVLVTTLIQGPEEQS
>Mature_389_residues
MFRILLAAFVLVASTLTAAAFETRASAAFVMDQTTGTVLLNKNADAPLPPASMSKLMTLYMAFEAVRRGKADGGLDLNER
LPVSEHAQSYGGSSMFLRSGETVSVEDLLRGIIVVSGNDACVVIAEALSPDGTEYGFARMMTQRAQQLGMNNSVFINASG
WPQTGHVMSMRDLAILADRLITDFPEFYPMFAETEFPFDNRVPSNSRNRNPVLTMGIGADGLKTGHTQEAGYGLVGSAKQ
GDRRIIFVITGLETTAARAQESQAIVNWAFRQFAMRDIGKAGQEFAKADVWMGSSPQVGLVAAEDMSVLMPALAEREIEA
EVVFTGPIEAPIAKGDPLGELVFTPEGLPEMRLPLVADQDVPSGGFVTRMMTAAMVLVTTLIQGPEEQS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=380, Percent_Identity=35.7894736842105, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1786851, Length=355, Percent_Identity=33.8028169014084, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI87082022, Length=355, Percent_Identity=31.830985915493, Blast_Score=176, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41812; Mature: 41812

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRILLAAFVLVASTLTAAAFETRASAAFVMDQTTGTVLLNKNADAPLPPASMSKLMTLY
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHH
MAFEAVRRGKADGGLDLNERLPVSEHAQSYGGSSMFLRSGETVSVEDLLRGIIVVSGNDA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCEEEHHHHHCCEEEEECCCE
CVVIAEALSPDGTEYGFARMMTQRAQQLGMNNSVFINASGWPQTGHVMSMRDLAILADRL
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEHHHHHHHHHHHH
ITDFPEFYPMFAETEFPFDNRVPSNSRNRNPVLTMGIGADGLKTGHTQEAGYGLVGSAKQ
HHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCC
GDRRIIFVITGLETTAARAQESQAIVNWAFRQFAMRDIGKAGQEFAKADVWMGSSPQVGL
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VAAEDMSVLMPALAEREIEAEVVFTGPIEAPIAKGDPLGELVFTPEGLPEMRLPLVADQD
EECCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCC
VPSGGFVTRMMTAAMVLVTTLIQGPEEQS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFRILLAAFVLVASTLTAAAFETRASAAFVMDQTTGTVLLNKNADAPLPPASMSKLMTLY
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHH
MAFEAVRRGKADGGLDLNERLPVSEHAQSYGGSSMFLRSGETVSVEDLLRGIIVVSGNDA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCEEEHHHHHCCEEEEECCCE
CVVIAEALSPDGTEYGFARMMTQRAQQLGMNNSVFINASGWPQTGHVMSMRDLAILADRL
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEHHHHHHHHHHHH
ITDFPEFYPMFAETEFPFDNRVPSNSRNRNPVLTMGIGADGLKTGHTQEAGYGLVGSAKQ
HHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCC
GDRRIIFVITGLETTAARAQESQAIVNWAFRQFAMRDIGKAGQEFAKADVWMGSSPQVGL
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VAAEDMSVLMPALAEREIEAEVVFTGPIEAPIAKGDPLGELVFTPEGLPEMRLPLVADQD
EECCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCC
VPSGGFVTRMMTAAMVLVTTLIQGPEEQS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]