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The map label for this gene is cobS [H]

Identifier: 110680517

GI number: 110680517

Start: 3203245

End: 3204231

Strand: Direct

Name: cobS [H]

Synonym: RD1_3339

Alternate gene names: 110680517

Gene position: 3203245-3204231 (Clockwise)

Preceding gene: 110680516

Following gene: 110680518

Centisome position: 77.5

GC content: 58.36

Gene sequence:

>987_bases
ATGGCCGATGGCGCACTGGACATTAATACAAAGCCGACCGAAGACATCAATGTCCGTGACGTGTTTGGCATTGATACAGA
TATGGTCGTGAAAGGCTTTGCCGAGGCCAGTGACCGGGTCCCGGACGTGGACTCGACGTATAAATTCGACCCCGACACGA
CGCTGGCGATCCTTGCGGGTTTTGCGCACAACCGCCGGGTCATGATCCAGGGGTATCATGGCACGGGTAAATCGACCCAT
ATCGAACAGGTGGCCGCGCGTCTGAACTGGCCTGCCGTGCGCGTGAACCTCGACAGCCACATCAGCCGGATCGACCTGAT
CGGCAAGGATGCGATCAAGCTGAAAGACGGCAAGCAGGTCACCGATTTTCAGGAGGGCATCCTGCCCTGGGCGCTGAGCA
ACCCGACCGCCATCGTCTTCGATGAATATGATGCCGGCCGTGCGGATGTGATGTTCGTGATCCAGCGGGTGCTGGAGGTG
GATGGCAAGCTGACCCTGCTCGATCAGAACAAGGTTATCACGCCGCACCCCTATTTCCGGATTTTCGCGACGGCAAACAC
CGTTGGTCTTGGCGACACGACCGGCCTTTATCATGGCACACAGCAGATCAACCAGGGCCAGATGGACCGCTGGTCGCTGG
TGGCGTCGCTGAACTACCTCAGCATTGATGCCGAAACCGCCATCGTGCTCAGCAAGAACCCGCATTACAACACCGAAAAA
GGGCGCAAGACCGTCAAACAGATGGTCACAGTTGCAGACCTCACACGGACCGCCTTCATGAATGGTGATCTGTCCACCGT
GATGTCCCCGCGCACCGTGATCGCATGGGCCCAGAACGCCGAGATTTTCCGCAACGTGGGCTATGCCTTCCGCCTGTCCT
TCCTGAACAAATGCGACGAGCTGGAACGCCAGACGGTCGCCGAGTTCTACCAACGCCTGTTCGACGAGGAACTGCCCGAA
AGCGCGGCAAGCCTGAGCTTGGGGTAA

Upstream 100 bases:

>100_bases
TATCACCGCCCTTTCCCTTGCACCTGCTTGCAATATATTGCACGAGATGGCGCAGGTTCGCACCTGCCCCTCAACCACGT
AATTCGAAGGACCAATTCTC

Downstream 100 bases:

>100_bases
GGTGCTGAACGTGGCGCGGAGACCCCGTGCCAATCCGATGGGAACAACCGTATGAGCAAGCCTTCTGACAATCCCGCAGA
TGCCTTTAAAAAGGCGCTGA

Product: aerobic cobaltochelatase CobS subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MADGALDINTKPTEDINVRDVFGIDTDMVVKGFAEASDRVPDVDSTYKFDPDTTLAILAGFAHNRRVMIQGYHGTGKSTH
IEQVAARLNWPAVRVNLDSHISRIDLIGKDAIKLKDGKQVTDFQEGILPWALSNPTAIVFDEYDAGRADVMFVIQRVLEV
DGKLTLLDQNKVITPHPYFRIFATANTVGLGDTTGLYHGTQQINQGQMDRWSLVASLNYLSIDAETAIVLSKNPHYNTEK
GRKTVKQMVTVADLTRTAFMNGDLSTVMSPRTVIAWAQNAEIFRNVGYAFRLSFLNKCDELERQTVAEFYQRLFDEELPE
SAASLSLG

Sequences:

>Translated_328_residues
MADGALDINTKPTEDINVRDVFGIDTDMVVKGFAEASDRVPDVDSTYKFDPDTTLAILAGFAHNRRVMIQGYHGTGKSTH
IEQVAARLNWPAVRVNLDSHISRIDLIGKDAIKLKDGKQVTDFQEGILPWALSNPTAIVFDEYDAGRADVMFVIQRVLEV
DGKLTLLDQNKVITPHPYFRIFATANTVGLGDTTGLYHGTQQINQGQMDRWSLVASLNYLSIDAETAIVLSKNPHYNTEK
GRKTVKQMVTVADLTRTAFMNGDLSTVMSPRTVIAWAQNAEIFRNVGYAFRLSFLNKCDELERQTVAEFYQRLFDEELPE
SAASLSLG
>Mature_327_residues
ADGALDINTKPTEDINVRDVFGIDTDMVVKGFAEASDRVPDVDSTYKFDPDTTLAILAGFAHNRRVMIQGYHGTGKSTHI
EQVAARLNWPAVRVNLDSHISRIDLIGKDAIKLKDGKQVTDFQEGILPWALSNPTAIVFDEYDAGRADVMFVIQRVLEVD
GKLTLLDQNKVITPHPYFRIFATANTVGLGDTTGLYHGTQQINQGQMDRWSLVASLNYLSIDAETAIVLSKNPHYNTEKG
RKTVKQMVTVADLTRTAFMNGDLSTVMSPRTVIAWAQNAEIFRNVGYAFRLSFLNKCDELERQTVAEFYQRLFDEELPES
AASLSLG

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=315, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI161076560, Length=205, Percent_Identity=28.780487804878, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076562, Length=205, Percent_Identity=28.780487804878, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36523; Mature: 36392

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGALDINTKPTEDINVRDVFGIDTDMVVKGFAEASDRVPDVDSTYKFDPDTTLAILAG
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHEEH
FAHNRRVMIQGYHGTGKSTHIEQVAARLNWPAVRVNLDSHISRIDLIGKDAIKLKDGKQV
HCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHEECCCCCEEECCCCCC
TDFQEGILPWALSNPTAIVFDEYDAGRADVMFVIQRVLEVDGKLTLLDQNKVITPHPYFR
HHHHHCCCCEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEE
IFATANTVGLGDTTGLYHGTQQINQGQMDRWSLVASLNYLSIDAETAIVLSKNPHYNTEK
EEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHEEECEEEEECCCEEEEEECCCCCCCHH
GRKTVKQMVTVADLTRTAFMNGDLSTVMSPRTVIAWAQNAEIFRNVGYAFRLSFLNKCDE
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCHHHHHHCCHHHHHHHHHHHHH
LERQTVAEFYQRLFDEELPESAASLSLG
HHHHHHHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure 
ADGALDINTKPTEDINVRDVFGIDTDMVVKGFAEASDRVPDVDSTYKFDPDTTLAILAG
CCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHEEH
FAHNRRVMIQGYHGTGKSTHIEQVAARLNWPAVRVNLDSHISRIDLIGKDAIKLKDGKQV
HCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHEECCCCCEEECCCCCC
TDFQEGILPWALSNPTAIVFDEYDAGRADVMFVIQRVLEVDGKLTLLDQNKVITPHPYFR
HHHHHCCCCEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEE
IFATANTVGLGDTTGLYHGTQQINQGQMDRWSLVASLNYLSIDAETAIVLSKNPHYNTEK
EEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHEEECEEEEECCCEEEEEECCCCCCCHH
GRKTVKQMVTVADLTRTAFMNGDLSTVMSPRTVIAWAQNAEIFRNVGYAFRLSFLNKCDE
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCHHHHHHCCHHHHHHHHHHHHH
LERQTVAEFYQRLFDEELPESAASLSLG
HHHHHHHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]