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The map label for this gene is surE

Identifier: 110680429

GI number: 110680429

Start: 3117149

End: 3117934

Strand: Direct

Name: surE

Synonym: RD1_3249

Alternate gene names: 110680429

Gene position: 3117149-3117934 (Clockwise)

Preceding gene: 110680428

Following gene: 110680430

Centisome position: 75.42

GC content: 61.32

Gene sequence:

>786_bases
ATGCGCATTTTGATTACAAACGACGATGGGATAAACGCACCGGGACTGATGGTTTTGCATGAGATCGCGACCAGACTGGC
CGGGCAGGATGGCGAGGTCTGGACCGTCGCACCTGCGTTCGAACAATCCGGCGTCGGCCATTGCATCAGCTACACCCGCC
CCATGATGGTTGCGCAAATGGGCCCGCGCCGCTTCGCCGCCGAAGGCTCACCGGCAGATTGCGTGCTGGCCGGCCTGCAC
GATGTGATGAAAGACAGCCCACCCGATCTGGTGCTTTCGGGCGTGAACCGGGGCAATAACTCCGCTGAAAACACGCTTTA
CTCGGGCACCATCGGCGGCGCGATGGAAGCAGCCCTGCAAGGGTTACCCGCGATTGCCCTGTCGCAATACTACGGGCCGC
GCAACAACGCGATCGAGAACCCTTTCGAGGCCTCAGCACAGCATGGTGTCGATGTGGTGCAGCGCATCCTTGCGCACACA
CCGCAGGAAACGGGTGGCTATCGTCTGTTTTACAATGTGAACTTCCCTCCTGTTCCGGGCGACGAAGTCCTCGGCATCCG
CTTGGCAACGCAGGGCTTCCGCGAGGGGCTGGGCTTTTCGACCGAGCCGCATAATGCCCCATCGGGTCGGCGGTTCTTGT
GGATCAAGGGCGGCGATCAGCATCGCCCGACCGCACCCGGATCTGACGCACAGTTGAACCTTGAGGGGTACATCTCGGTC
ACGCCGATGCGGGCGGATTTGACCGCGCATGACATGATGGCCCCGCTGGCGGGCATCAATACATGA

Upstream 100 bases:

>100_bases
TCACAACTCTGAGCTTTCGAGCTGCAAAACAGCTGACAAGGGGCGGCTTCTCTTGCTGCGCTCCTATCGCTCGCCTATCA
AAGCCAAAAGGGGCCTTGAT

Downstream 100 bases:

>100_bases
TGACAGAAATGTCTGAGGCAGAACGCAAGATGCAGTTCCTCTATGCCCTGCGCTCCAAGGGTGTCACAGATAAACGCGTG
CTCTCGGCCATGGAAAACAT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRILITNDDGINAPGLMVLHEIATRLAGQDGEVWTVAPAFEQSGVGHCISYTRPMMVAQMGPRRFAAEGSPADCVLAGLH
DVMKDSPPDLVLSGVNRGNNSAENTLYSGTIGGAMEAALQGLPAIALSQYYGPRNNAIENPFEASAQHGVDVVQRILAHT
PQETGGYRLFYNVNFPPVPGDEVLGIRLATQGFREGLGFSTEPHNAPSGRRFLWIKGGDQHRPTAPGSDAQLNLEGYISV
TPMRADLTAHDMMAPLAGINT

Sequences:

>Translated_261_residues
MRILITNDDGINAPGLMVLHEIATRLAGQDGEVWTVAPAFEQSGVGHCISYTRPMMVAQMGPRRFAAEGSPADCVLAGLH
DVMKDSPPDLVLSGVNRGNNSAENTLYSGTIGGAMEAALQGLPAIALSQYYGPRNNAIENPFEASAQHGVDVVQRILAHT
PQETGGYRLFYNVNFPPVPGDEVLGIRLATQGFREGLGFSTEPHNAPSGRRFLWIKGGDQHRPTAPGSDAQLNLEGYISV
TPMRADLTAHDMMAPLAGINT
>Mature_261_residues
MRILITNDDGINAPGLMVLHEIATRLAGQDGEVWTVAPAFEQSGVGHCISYTRPMMVAQMGPRRFAAEGSPADCVLAGLH
DVMKDSPPDLVLSGVNRGNNSAENTLYSGTIGGAMEAALQGLPAIALSQYYGPRNNAIENPFEASAQHGVDVVQRILAHT
PQETGGYRLFYNVNFPPVPGDEVLGIRLATQGFREGLGFSTEPHNAPSGRRFLWIKGGDQHRPTAPGSDAQLNLEGYISV
TPMRADLTAHDMMAPLAGINT

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=251, Percent_Identity=33.0677290836653, Blast_Score=120, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6319570, Length=201, Percent_Identity=29.3532338308458, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_ROSDO (Q163U3)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683436.1
- ProteinModelPortal:   Q163U3
- SMR:   Q163U3
- STRING:   Q163U3
- GeneID:   4198559
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3249
- NMPDR:   fig|375451.6.peg.3017
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   VIGICEM
- PhylomeDB:   Q163U3
- ProtClustDB:   PRK13931
- BioCyc:   RDEN375451:RD1_3249-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27845; Mature: 27845

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILITNDDGINAPGLMVLHEIATRLAGQDGEVWTVAPAFEQSGVGHCISYTRPMMVAQM
CEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCHHHHHHCHHHHHHC
GPRRFAAEGSPADCVLAGLHDVMKDSPPDLVLSGVNRGNNSAENTLYSGTIGGAMEAALQ
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHCEEECCCCCHHHHHHHH
GLPAIALSQYYGPRNNAIENPFEASAQHGVDVVQRILAHTPQETGGYRLFYNVNFPPVPG
CCCHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC
DEVLGIRLATQGFREGLGFSTEPHNAPSGRRFLWIKGGDQHRPTAPGSDAQLNLEGYISV
CCEEEEEEHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEE
TPMRADLTAHDMMAPLAGINT
EEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MRILITNDDGINAPGLMVLHEIATRLAGQDGEVWTVAPAFEQSGVGHCISYTRPMMVAQM
CEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCHHHHHHCHHHHHHC
GPRRFAAEGSPADCVLAGLHDVMKDSPPDLVLSGVNRGNNSAENTLYSGTIGGAMEAALQ
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHCEEECCCCCHHHHHHHH
GLPAIALSQYYGPRNNAIENPFEASAQHGVDVVQRILAHTPQETGGYRLFYNVNFPPVPG
CCCHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC
DEVLGIRLATQGFREGLGFSTEPHNAPSGRRFLWIKGGDQHRPTAPGSDAQLNLEGYISV
CCEEEEEEHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEE
TPMRADLTAHDMMAPLAGINT
EEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA