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The map label for this gene is alr

Identifier: 110680421

GI number: 110680421

Start: 3109167

End: 3110201

Strand: Direct

Name: alr

Synonym: RD1_3240

Alternate gene names: 110680421

Gene position: 3109167-3110201 (Clockwise)

Preceding gene: 110680420

Following gene: 110680422

Centisome position: 75.23

GC content: 62.32

Gene sequence:

>1035_bases
ATGAGTACCGCTGTCCTGACAATTGATCTTTCTGCGCTCGCTGCAAACTGGCGCAGTCTGAACGCGCTATCAGACGTCGA
AACCGCCGCTGTCGTCAAAGCCAACGCCTATGGCCTTGGCGTAGGCACTGCGGCATCGGCCCTTGCTGAGGCCGGTGCGC
GTCATTTCTTTGTCGCCGTTGCCGAAGAGGGCGTGGCACTGCGGCAGGCGCTTGGCGCGGGGCCGCAGATCAGCGTATTT
TCCGGCCATATGGCGGGGGATACCGCCTTGATCCGGGACGCGGGCCTCACGCCGATGATCAATTCCATCGACCAGATGAT
CCGACATGTGGAGGCCCTGCCCGAGCATGACTTTGGCATCCAGCTTGATACCGGCATGAACCGGCTCGGCATGGAAGACG
GCGAATGGCGCGCGGTGCGCGAGGTCGCCACACAGCGCCCTCCCAGCCTCGTGATGTCGCACCTTGCCTGCGCGGATGAG
CCGTCCCACCAGATGAACCGCCAACAGTTGGACTGCTTTGTCGAGATGACACAGGACATCACCGCGCCACGCTCGCTTGC
GGCGACAGGCGGGATTTTGATGGGGCCTGACTATCATTTCGACCTGACGCGCCCGGGGATTGGCCTTTACGGCGGTCTGC
CCTTTGTCGACGCGCTGCCGGTGGTGCAGCTTGATGTGCCGGTCATTCAGGTGCGCGACGTTCACCCCGGCGAAACCGTG
GGCTACGCCAACACATGGACGGCCACCGCGCCTGCGCGCATTGCCACGATCTCGGCAGGTTATGCCGATGGTCTGATCCG
CGCGATGGGGGCCAAGGCACGGCTGCATGCTGGCGATACTGCCCTACCCGTCGTGGGCCGCGTGTCCATGGATCTGATCG
GTGTCGATGTGACGGCACTGGGCAGCGACCCGGACAGCCTGCAGCTTATCGGGCGTCACCAGTCAGTCGATACGGTTGCG
GGCTTTGCAGATACCATCGGATATGAAATACTGACCTCTCTCGGCGACAGATACAAAAGGGTCTATACGCAGTGA

Upstream 100 bases:

>100_bases
TTCAGGTTATAAAAGCTTCAACCGGCAATTTCCGGCGGAGGTCGCACCGCATCTTTGCCCAAAGGCTTGACCTTGCGCGC
ATTCGTGTCATGAACGCGCC

Downstream 100 bases:

>100_bases
AGTTTTTCGCCGTCATAGGCCGCGTTGTCCTGAGCGCATTGGCAGCCATTGGCCGGATCGCCATTTTTGGCGGCCAGACG
ATCGGCCATCTTGCCCGACC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSTAVLTIDLSALAANWRSLNALSDVETAAVVKANAYGLGVGTAASALAEAGARHFFVAVAEEGVALRQALGAGPQISVF
SGHMAGDTALIRDAGLTPMINSIDQMIRHVEALPEHDFGIQLDTGMNRLGMEDGEWRAVREVATQRPPSLVMSHLACADE
PSHQMNRQQLDCFVEMTQDITAPRSLAATGGILMGPDYHFDLTRPGIGLYGGLPFVDALPVVQLDVPVIQVRDVHPGETV
GYANTWTATAPARIATISAGYADGLIRAMGAKARLHAGDTALPVVGRVSMDLIGVDVTALGSDPDSLQLIGRHQSVDTVA
GFADTIGYEILTSLGDRYKRVYTQ

Sequences:

>Translated_344_residues
MSTAVLTIDLSALAANWRSLNALSDVETAAVVKANAYGLGVGTAASALAEAGARHFFVAVAEEGVALRQALGAGPQISVF
SGHMAGDTALIRDAGLTPMINSIDQMIRHVEALPEHDFGIQLDTGMNRLGMEDGEWRAVREVATQRPPSLVMSHLACADE
PSHQMNRQQLDCFVEMTQDITAPRSLAATGGILMGPDYHFDLTRPGIGLYGGLPFVDALPVVQLDVPVIQVRDVHPGETV
GYANTWTATAPARIATISAGYADGLIRAMGAKARLHAGDTALPVVGRVSMDLIGVDVTALGSDPDSLQLIGRHQSVDTVA
GFADTIGYEILTSLGDRYKRVYTQ
>Mature_343_residues
STAVLTIDLSALAANWRSLNALSDVETAAVVKANAYGLGVGTAASALAEAGARHFFVAVAEEGVALRQALGAGPQISVFS
GHMAGDTALIRDAGLTPMINSIDQMIRHVEALPEHDFGIQLDTGMNRLGMEDGEWRAVREVATQRPPSLVMSHLACADEP
SHQMNRQQLDCFVEMTQDITAPRSLAATGGILMGPDYHFDLTRPGIGLYGGLPFVDALPVVQLDVPVIQVRDVHPGETVG
YANTWTATAPARIATISAGYADGLIRAMGAKARLHAGDTALPVVGRVSMDLIGVDVTALGSDPDSLQLIGRHQSVDTVAG
FADTIGYEILTSLGDRYKRVYTQ

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=359, Percent_Identity=33.983286908078, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787439, Length=354, Percent_Identity=30.7909604519774, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_ROSDO (Q163V1)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683428.1
- ProteinModelPortal:   Q163V1
- SMR:   Q163V1
- STRING:   Q163V1
- GeneID:   4198551
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3240
- NMPDR:   fig|375451.6.peg.3009
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   YCTPDKI
- PhylomeDB:   Q163V1
- ProtClustDB:   CLSK933932
- BioCyc:   RDEN375451:RD1_3240-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 36341; Mature: 36210

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 33-33 ACT_SITE 242-242

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAVLTIDLSALAANWRSLNALSDVETAAVVKANAYGLGVGTAASALAEAGARHFFVAV
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCEEEEEE
AEEGVALRQALGAGPQISVFSGHMAGDTALIRDAGLTPMINSIDQMIRHVEALPEHDFGI
ECCCHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCE
QLDTGMNRLGMEDGEWRAVREVATQRPPSLVMSHLACADEPSHQMNRQQLDCFVEMTQDI
EECCCCHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TAPRSLAATGGILMGPDYHFDLTRPGIGLYGGLPFVDALPVVQLDVPVIQVRDVHPGETV
CCCHHHHHCCCEEECCCCEEECCCCCCCCCCCCCHHHCCCEEEECCCEEEEEECCCCCCC
GYANTWTATAPARIATISAGYADGLIRAMGAKARLHAGDTALPVVGRVSMDLIGVDVTAL
CCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEEEEEE
GSDPDSLQLIGRHQSVDTVAGFADTIGYEILTSLGDRYKRVYTQ
CCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STAVLTIDLSALAANWRSLNALSDVETAAVVKANAYGLGVGTAASALAEAGARHFFVAV
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCEEEEEE
AEEGVALRQALGAGPQISVFSGHMAGDTALIRDAGLTPMINSIDQMIRHVEALPEHDFGI
ECCCHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCE
QLDTGMNRLGMEDGEWRAVREVATQRPPSLVMSHLACADEPSHQMNRQQLDCFVEMTQDI
EECCCCHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TAPRSLAATGGILMGPDYHFDLTRPGIGLYGGLPFVDALPVVQLDVPVIQVRDVHPGETV
CCCHHHHHCCCEEECCCCEEECCCCCCCCCCCCCHHHCCCEEEECCCEEEEEECCCCCCC
GYANTWTATAPARIATISAGYADGLIRAMGAKARLHAGDTALPVVGRVSMDLIGVDVTAL
CCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEEEEEE
GSDPDSLQLIGRHQSVDTVAGFADTIGYEILTSLGDRYKRVYTQ
CCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA