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The map label for this gene is fucK [H]

Identifier: 110680265

GI number: 110680265

Start: 2947011

End: 2948381

Strand: Reverse

Name: fucK [H]

Synonym: RD1_3075

Alternate gene names: 110680265

Gene position: 2948381-2947011 (Counterclockwise)

Preceding gene: 110680266

Following gene: 110680264

Centisome position: 71.34

GC content: 61.12

Gene sequence:

>1371_bases
ATGAAAAACCCGCGCCACATTGCCGTAATTGACATCGGGAAAACGAACGCAAAACTCGCGCTTGTTGATCTGCAGAACCA
TCGGGAAATTGCCGTGCTGACGCGCCCCAACACGGTATTGCCCGGCCCGCCCTGGCGTCATTTCGATACAGATGGGCACT
GGGATTTTCTGCTGGCTGCGCTCAAAGTGCTGCACGGTGAACATGGCATTGATGCGATTTCCATCTCCACCCACGGCGCC
AGCGTCGTTCTGCTTGACGCACAAGGGGACCTTGCGGCACCGGTGCTGGATTATGAGCACCCGATCCCGGCTGACATCGC
GCAGGCCTATGACGCGATCCGTCCGCCTTTTGCGCAAACCGGGTCGGCGCGACTTGCCAACGGGCTGAATGTGGGGGCGC
AGTTGTTTTATCAATTCGCTCAAGACCCGGGCTTGCGTGATCGCACGCGCCATATCGTGGGCTATCCGCAGTACTGGGGC
CACCGTCTCACGGGGGAATTCGCCTGGGATGTGACCTCGATCGGGTGCCATACAGACCTGTGGGAACCAGTCACGGGTCG
GTTTTCTTCGCTGGTCGACAGGCTTGGTATTGCGGAAAAGCTAGCTCCGGTGCGGCATTGCGCTGATGTTCTCGGGTCCA
TCTTGCCGGAAGTCGCCGCCGCCACCGGGCTGTCCGCGGATACGCCCGTCACCGTGGGTATTCACGATTCCAACGCGTCG
CTGTACCCGCATCTGTTGACCCAAGAGGCCCCGTTTTCGGTTGTCTCAACGGGCACCTGGGTGGTCGCCATGGCCGTCGG
AAGCAAGGTGCCGGGCCTTGACCCGACGCGCGATACGCTCGTCAACGTGAATGCGATGGGCCAACCCGTTCCCTCCGCGC
GCTTCATGGGAGGGCGGGAGCATGAAGTCATTCAGGCGGGTCAGCCCTGCCCACCAACACCGCAGGACGTGGCGCAGGTT
CTGGCCGACTCCGTCATGATCCTGCCCGCCGTGGAACCCGCGTCGGGGCCATTTCAGGGGCGCAAAATGCGCTGGAGCGG
GCCTGAACCCGCACCCGGCACCGGGCCGCGTTCAGCGGCATTGTCATTTTACCTTGCACTGATGACGAGCACCTGCCTTG
CGCTGATAGCGGCCAGGGGCGTGACCATCGTCGAAGGCCCATTTGCCCAGAACCGGGAATTCAAATCCATGCTGTCAGTC
GCAACAGGTCGCGCGGTTCTGCATAGCCAATCCGCGACAGGAACAAGCATGGGTGCATCACTCCTTTTCAGCTCTGACCG
AACACCGCCGCTGCCACAAACGAACGTCTCTGAGGAGGATGCACAAGCCTACCGAACCTACGCCAAAGAGTGGCACCAGC
AGATCACCTAA

Upstream 100 bases:

>100_bases
CGATCATGCGGAAATGGTGGGCGCATATGGCCGATATCATGGAGACGGGGCCGGATGATGCACCCATTGCGGTCCCGCTG
ACGCCTGTGTTTCACATGCC

Downstream 100 bases:

>100_bases
AGCGTCTTGCGAAAAACCTGAACCGCATGACGCTGCCTGCAATCGACGACTTCAGTGCGGTACCGGATGTTTGATAGCGT
GGGCATTTCGTCAGACGCTC

Product: carbohydrate kinases, putative

Products: NA

Alternate protein names: L-fuculose kinase [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MKNPRHIAVIDIGKTNAKLALVDLQNHREIAVLTRPNTVLPGPPWRHFDTDGHWDFLLAALKVLHGEHGIDAISISTHGA
SVVLLDAQGDLAAPVLDYEHPIPADIAQAYDAIRPPFAQTGSARLANGLNVGAQLFYQFAQDPGLRDRTRHIVGYPQYWG
HRLTGEFAWDVTSIGCHTDLWEPVTGRFSSLVDRLGIAEKLAPVRHCADVLGSILPEVAAATGLSADTPVTVGIHDSNAS
LYPHLLTQEAPFSVVSTGTWVVAMAVGSKVPGLDPTRDTLVNVNAMGQPVPSARFMGGREHEVIQAGQPCPPTPQDVAQV
LADSVMILPAVEPASGPFQGRKMRWSGPEPAPGTGPRSAALSFYLALMTSTCLALIAARGVTIVEGPFAQNREFKSMLSV
ATGRAVLHSQSATGTSMGASLLFSSDRTPPLPQTNVSEEDAQAYRTYAKEWHQQIT

Sequences:

>Translated_456_residues
MKNPRHIAVIDIGKTNAKLALVDLQNHREIAVLTRPNTVLPGPPWRHFDTDGHWDFLLAALKVLHGEHGIDAISISTHGA
SVVLLDAQGDLAAPVLDYEHPIPADIAQAYDAIRPPFAQTGSARLANGLNVGAQLFYQFAQDPGLRDRTRHIVGYPQYWG
HRLTGEFAWDVTSIGCHTDLWEPVTGRFSSLVDRLGIAEKLAPVRHCADVLGSILPEVAAATGLSADTPVTVGIHDSNAS
LYPHLLTQEAPFSVVSTGTWVVAMAVGSKVPGLDPTRDTLVNVNAMGQPVPSARFMGGREHEVIQAGQPCPPTPQDVAQV
LADSVMILPAVEPASGPFQGRKMRWSGPEPAPGTGPRSAALSFYLALMTSTCLALIAARGVTIVEGPFAQNREFKSMLSV
ATGRAVLHSQSATGTSMGASLLFSSDRTPPLPQTNVSEEDAQAYRTYAKEWHQQIT
>Mature_456_residues
MKNPRHIAVIDIGKTNAKLALVDLQNHREIAVLTRPNTVLPGPPWRHFDTDGHWDFLLAALKVLHGEHGIDAISISTHGA
SVVLLDAQGDLAAPVLDYEHPIPADIAQAYDAIRPPFAQTGSARLANGLNVGAQLFYQFAQDPGLRDRTRHIVGYPQYWG
HRLTGEFAWDVTSIGCHTDLWEPVTGRFSSLVDRLGIAEKLAPVRHCADVLGSILPEVAAATGLSADTPVTVGIHDSNAS
LYPHLLTQEAPFSVVSTGTWVVAMAVGSKVPGLDPTRDTLVNVNAMGQPVPSARFMGGREHEVIQAGQPCPPTPQDVAQV
LADSVMILPAVEPASGPFQGRKMRWSGPEPAPGTGPRSAALSFYLALMTSTCLALIAARGVTIVEGPFAQNREFKSMLSV
ATGRAVLHSQSATGTSMGASLLFSSDRTPPLPQTNVSEEDAQAYRTYAKEWHQQIT

Specific function: Fucose metabolism; second step. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789168, Length=273, Percent_Identity=25.6410256410256, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR013450 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.51 [H]

Molecular weight: Translated: 48855; Mature: 48855

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNPRHIAVIDIGKTNAKLALVDLQNHREIAVLTRPNTVLPGPPWRHFDTDGHWDFLLAA
CCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHH
LKVLHGEHGIDAISISTHGASVVLLDAQGDLAAPVLDYEHPIPADIAQAYDAIRPPFAQT
HHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
GSARLANGLNVGAQLFYQFAQDPGLRDRTRHIVGYPQYWGHRLTGEFAWDVTSIGCHTDL
CCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHEECCHHHHCCCCCCEEEEEEEECCCCCCC
WEPVTGRFSSLVDRLGIAEKLAPVRHCADVLGSILPEVAAATGLSADTPVTVGIHDSNAS
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
LYPHLLTQEAPFSVVSTGTWVVAMAVGSKVPGLDPTRDTLVNVNAMGQPVPSARFMGGRE
CCHHHHCCCCCCEEEECCCEEEEEECCCCCCCCCCCHHHEEEECCCCCCCCCHHHCCCCC
HEVIQAGQPCPPTPQDVAQVLADSVMILPAVEPASGPFQGRKMRWSGPEPAPGTGPRSAA
HHHHHCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHH
LSFYLALMTSTCLALIAARGVTIVEGPFAQNREFKSMLSVATGRAVLHSQSATGTSMGAS
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCHHHEECCCCCCCHHCHH
LLFSSDRTPPLPQTNVSEEDAQAYRTYAKEWHQQIT
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNPRHIAVIDIGKTNAKLALVDLQNHREIAVLTRPNTVLPGPPWRHFDTDGHWDFLLAA
CCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHH
LKVLHGEHGIDAISISTHGASVVLLDAQGDLAAPVLDYEHPIPADIAQAYDAIRPPFAQT
HHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
GSARLANGLNVGAQLFYQFAQDPGLRDRTRHIVGYPQYWGHRLTGEFAWDVTSIGCHTDL
CCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHEECCHHHHCCCCCCEEEEEEEECCCCCCC
WEPVTGRFSSLVDRLGIAEKLAPVRHCADVLGSILPEVAAATGLSADTPVTVGIHDSNAS
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
LYPHLLTQEAPFSVVSTGTWVVAMAVGSKVPGLDPTRDTLVNVNAMGQPVPSARFMGGRE
CCHHHHCCCCCCEEEECCCEEEEEECCCCCCCCCCCHHHEEEECCCCCCCCCHHHCCCCC
HEVIQAGQPCPPTPQDVAQVLADSVMILPAVEPASGPFQGRKMRWSGPEPAPGTGPRSAA
HHHHHCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHH
LSFYLALMTSTCLALIAARGVTIVEGPFAQNREFKSMLSVATGRAVLHSQSATGTSMGAS
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCHHHEECCCCCCCHHCHH
LLFSSDRTPPLPQTNVSEEDAQAYRTYAKEWHQQIT
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]