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The map label for this gene is coxL [H]

Identifier: 110680172

GI number: 110680172

Start: 2849721

End: 2852093

Strand: Reverse

Name: coxL [H]

Synonym: RD1_2973

Alternate gene names: 110680172

Gene position: 2852093-2849721 (Counterclockwise)

Preceding gene: 110680173

Following gene: 110680171

Centisome position: 69.01

GC content: 60.51

Gene sequence:

>2373_bases
ATGCCAAAAGATGGAGGCATTGGTGCCAGTTCAAAGCGCCGCGAAGACGTCCGGTTCCTGACCGGAGCAGGGAATTACAC
AGATGACATCAACATCCGGGGGCAGGCACATGTGTTTTTCCTGCGCTCTGATGTGGCGCATGGCACGCTGAACAAGGTCG
ATACCACCGCCGCCGAAGGGATGCCGGGCGTGGTGCGGGTGTTTACCGGCGCGGATTTCGAAGCCGTGGGCGGCATGCCC
TGTGGCTGGCAGATCACCGACAAGCACGGCCAACCGATGCTGGAGCCAAAGCACCCGGTGCTGGCCCATGGCAAGGTGCG
CCATGTGGGCGAGCCGATCGCCGCGGTGGTTGCCGACACGCTGGAGCAGGCGCGCGATGCCGCCGAGGCGATCGAACTCG
ACATCTCCGAACTGCCCGCGGTTGTGGATATGAAGGCGGCGGTGACGGATGCCTCGCCCAAAGTGCATGATGATCTGCCC
TCAAACCTTTGTTATGACTGGGGTTTTGTCGAGGAAAACAAGGCCGCAACGGATGAAGCCTTTGAAAAGGCTGCGCATGT
CACGACGCTGGAACTGGTCAACAACCGGCTGGTCGCCAACCCGATGGAGCCGCGCGTCGCCGTTGGTGATTACTCAAGGG
CCACGGATGACCACACACTCTATACCACATCGCAGAACCCGCATGTGATCCGGCTTTTGATGGGTGCGTTCGTGCTGGGC
ATACCGGAGCATAAACTGCGTGTTGTCGCGCCGGATGTGGGCGGTGGTTTTGGCACCAAGATCTTCCATTATCAGGAGGA
GGCGTTCTGCACCTTCGCCGCCAAGGCCTGCAACCGTCCGGTCAAATGGACCTCCAGCCGCTCCGAAGCCTTCATGTCCG
ACGCCCATGGGCGTGACCATGTGACCAAGATCGAACTGGCGCTGGATGCGGACAACAACTTCACGGCACTGCGCACCGAA
ACATTCGCCAATATGGGGGCCTATCTGTCGACTTTTGCGCCCTCTATCCCGACGTGGCTGCATGGCACGTTGATGGCGGG
CAATTACAAGACCCCGCTGGTCTATGTGAACGTCAAGGCTGTCTTCACCAACACCGTGCCGGTGGATGCCTATCGCGGCG
CTGGCCGCCCCGAGGCGACGTTCCAGCTGGAGCGGGTCATCGACAAGGCAGCACTTGAACTTAAGGTCGATCCGGTGGAA
TTGCGGCGTCAGAACTTCATCACCGAATTCCCCTACGCCACGCCGGTTGCCGTTGAATATGACACCGGTGATTACCACGC
CACGATGGACAAGGTGCTGGAGATGTCAGACCGCGCCGGGTTCGAGGCACGCCGCAAGGAGAGCGAGGCACGAGGCAAGC
TGCGCGGCTTTGGCATCAACTGCTTTATCGAGGCCTGCGGCATTGCGCCCTCGAACCTTGTGGGGCAATTGGGCGCCCGC
GCGGGCCTCTATGAAAGCGCGACGGTGCGGGTCAATGCAACTGGCGGTCTCGTGGTGATGACGGGCAGCCACAGTCACGG
GCAGGGCCATGAAACGTCCTTTGCGCAGGTGGTGGCCGATATGATCGGCATTGACGAAAACATGGTCGAGATCGTCCATG
GTGATACGGCCAATACGCCTATGGGCATGGGCACATATGGCTCACGCTCCATCGCGGTTGGTGGGTCTGCCATGGTGCGC
GCGACCGAAAAGATCATCGCCAAGGCTAAGAAGATCGCCAGCCACCTGCTCGAAGCCTCCGAAGGGGATATCGAGCTTAA
GGATGGCGCGTTCTCTGTGGCTGGTACGGATAAATCCGTGGCCTGGGGGGATGTGACGCTGGCCGCCTATGTGCCGCATA
ACTACCCGCTGGAGGACATCGAACCGGGCCTTGAAGAGACGGCGTTTTACGATCCGTCAAACTTCACCTATCCGGCCGGG
GCCTATACCTGCGAAGTGGAAGTGGACCCGCAAACCGGTGTCGTCACCATCGAGCGGTTTGCCTCTGCGGATGATTTCGG
CAATGTGATCAACCCGATGATCGTCGAAGGTCAGGTGCATGGCGGGATCGCGCAGGGCATTGGTCAGGCGCTTTTGGAAA
ACTGCGCCTATGACGAAAACGGCCAGCTGCTGACGGCATCCTACATGGATTACACGATGCCGCGCGCGGATGATCTGCCG
GATATGACCCACTATATCGTGGATCATTCCTGTCAGACGCCCTGCACGCATAACCCACTGGGGGTGAAAGGCTGCGGCGA
GGCGGGGGCGATCGGCTCACCGCCGACCGTGATCAATGCCATCGTGGATGCGCTGCGCTCGGGTGGCCATGACGTCACAC
ATATCGACATGCCGGCGACACCGGCGCGGGTATGGGCGGCCATGCAGGGCTGA

Upstream 100 bases:

>100_bases
TCATGCGCGTGCCCTGCGTCGGTGGCCTAAGTGCCCCCGCGTATTGCAGCCGCGCCAGCCGGGTGAGGGCAAGCTTACCG
CAAGTTAAGGGAGAAGTAAT

Downstream 100 bases:

>100_bases
TCCCGCTGAACGGGGCGAGGGGCGTTTGCCTCTTGCCCCCAACAGGGAGTTTTAGGCCGAGGAAACGACGTGCTGTTCCC
GGCTTTGGAAAGGAAAGACA

Product: carbon monoxide dehydrogenase, large subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MPKDGGIGASSKRREDVRFLTGAGNYTDDINIRGQAHVFFLRSDVAHGTLNKVDTTAAEGMPGVVRVFTGADFEAVGGMP
CGWQITDKHGQPMLEPKHPVLAHGKVRHVGEPIAAVVADTLEQARDAAEAIELDISELPAVVDMKAAVTDASPKVHDDLP
SNLCYDWGFVEENKAATDEAFEKAAHVTTLELVNNRLVANPMEPRVAVGDYSRATDDHTLYTTSQNPHVIRLLMGAFVLG
IPEHKLRVVAPDVGGGFGTKIFHYQEEAFCTFAAKACNRPVKWTSSRSEAFMSDAHGRDHVTKIELALDADNNFTALRTE
TFANMGAYLSTFAPSIPTWLHGTLMAGNYKTPLVYVNVKAVFTNTVPVDAYRGAGRPEATFQLERVIDKAALELKVDPVE
LRRQNFITEFPYATPVAVEYDTGDYHATMDKVLEMSDRAGFEARRKESEARGKLRGFGINCFIEACGIAPSNLVGQLGAR
AGLYESATVRVNATGGLVVMTGSHSHGQGHETSFAQVVADMIGIDENMVEIVHGDTANTPMGMGTYGSRSIAVGGSAMVR
ATEKIIAKAKKIASHLLEASEGDIELKDGAFSVAGTDKSVAWGDVTLAAYVPHNYPLEDIEPGLEETAFYDPSNFTYPAG
AYTCEVEVDPQTGVVTIERFASADDFGNVINPMIVEGQVHGGIAQGIGQALLENCAYDENGQLLTASYMDYTMPRADDLP
DMTHYIVDHSCQTPCTHNPLGVKGCGEAGAIGSPPTVINAIVDALRSGGHDVTHIDMPATPARVWAAMQG

Sequences:

>Translated_790_residues
MPKDGGIGASSKRREDVRFLTGAGNYTDDINIRGQAHVFFLRSDVAHGTLNKVDTTAAEGMPGVVRVFTGADFEAVGGMP
CGWQITDKHGQPMLEPKHPVLAHGKVRHVGEPIAAVVADTLEQARDAAEAIELDISELPAVVDMKAAVTDASPKVHDDLP
SNLCYDWGFVEENKAATDEAFEKAAHVTTLELVNNRLVANPMEPRVAVGDYSRATDDHTLYTTSQNPHVIRLLMGAFVLG
IPEHKLRVVAPDVGGGFGTKIFHYQEEAFCTFAAKACNRPVKWTSSRSEAFMSDAHGRDHVTKIELALDADNNFTALRTE
TFANMGAYLSTFAPSIPTWLHGTLMAGNYKTPLVYVNVKAVFTNTVPVDAYRGAGRPEATFQLERVIDKAALELKVDPVE
LRRQNFITEFPYATPVAVEYDTGDYHATMDKVLEMSDRAGFEARRKESEARGKLRGFGINCFIEACGIAPSNLVGQLGAR
AGLYESATVRVNATGGLVVMTGSHSHGQGHETSFAQVVADMIGIDENMVEIVHGDTANTPMGMGTYGSRSIAVGGSAMVR
ATEKIIAKAKKIASHLLEASEGDIELKDGAFSVAGTDKSVAWGDVTLAAYVPHNYPLEDIEPGLEETAFYDPSNFTYPAG
AYTCEVEVDPQTGVVTIERFASADDFGNVINPMIVEGQVHGGIAQGIGQALLENCAYDENGQLLTASYMDYTMPRADDLP
DMTHYIVDHSCQTPCTHNPLGVKGCGEAGAIGSPPTVINAIVDALRSGGHDVTHIDMPATPARVWAAMQG
>Mature_789_residues
PKDGGIGASSKRREDVRFLTGAGNYTDDINIRGQAHVFFLRSDVAHGTLNKVDTTAAEGMPGVVRVFTGADFEAVGGMPC
GWQITDKHGQPMLEPKHPVLAHGKVRHVGEPIAAVVADTLEQARDAAEAIELDISELPAVVDMKAAVTDASPKVHDDLPS
NLCYDWGFVEENKAATDEAFEKAAHVTTLELVNNRLVANPMEPRVAVGDYSRATDDHTLYTTSQNPHVIRLLMGAFVLGI
PEHKLRVVAPDVGGGFGTKIFHYQEEAFCTFAAKACNRPVKWTSSRSEAFMSDAHGRDHVTKIELALDADNNFTALRTET
FANMGAYLSTFAPSIPTWLHGTLMAGNYKTPLVYVNVKAVFTNTVPVDAYRGAGRPEATFQLERVIDKAALELKVDPVEL
RRQNFITEFPYATPVAVEYDTGDYHATMDKVLEMSDRAGFEARRKESEARGKLRGFGINCFIEACGIAPSNLVGQLGARA
GLYESATVRVNATGGLVVMTGSHSHGQGHETSFAQVVADMIGIDENMVEIVHGDTANTPMGMGTYGSRSIAVGGSAMVRA
TEKIIAKAKKIASHLLEASEGDIELKDGAFSVAGTDKSVAWGDVTLAAYVPHNYPLEDIEPGLEETAFYDPSNFTYPAGA
YTCEVEVDPQTGVVTIERFASADDFGNVINPMIVEGQVHGGIAQGIGQALLENCAYDENGQLLTASYMDYTMPRADDLPD
MTHYIVDHSCQTPCTHNPLGVKGCGEAGAIGSPPTVINAIVDALRSGGHDVTHIDMPATPARVWAAMQG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=784, Percent_Identity=25.1275510204082, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI91823271, Length=811, Percent_Identity=23.6744759556104, Blast_Score=129, Evalue=1e-29,
Organism=Escherichia coli, GI1789230, Length=805, Percent_Identity=28.4472049689441, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1789246, Length=809, Percent_Identity=24.1038318912237, Blast_Score=185, Evalue=9e-48,
Organism=Escherichia coli, GI1786478, Length=739, Percent_Identity=25.575101488498, Blast_Score=116, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=799, Percent_Identity=25.7822277847309, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17539860, Length=792, Percent_Identity=25.1262626262626, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32566215, Length=545, Percent_Identity=24.954128440367, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17737937, Length=806, Percent_Identity=25.1861042183623, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24647199, Length=802, Percent_Identity=24.0648379052369, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24647201, Length=798, Percent_Identity=23.5588972431078, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24647193, Length=786, Percent_Identity=22.9007633587786, Blast_Score=97, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84874; Mature: 84743

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKDGGIGASSKRREDVRFLTGAGNYTDDINIRGQAHVFFLRSDVAHGTLNKVDTTAAEG
CCCCCCCCCCCCCCCCEEEEECCCCCCCCEEECCEEEEEEEECCCCCCCCCCCCCHHHCC
MPGVVRVFTGADFEAVGGMPCGWQITDKHGQPMLEPKHPVLAHGKVRHVGEPIAAVVADT
CCCEEEEEECCCHHHCCCCCCCCEEECCCCCCCCCCCCCCEECCCHHHCCCHHHHHHHHH
LEQARDAAEAIELDISELPAVVDMKAAVTDASPKVHDDLPSNLCYDWGFVEENKAATDEA
HHHHHHHHHHHHCCHHHCCHHEECHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHH
FEKAAHVTTLELVNNRLVANPMEPRVAVGDYSRATDDHTLYTTSQNPHVIRLLMGAFVLG
HHHHHHHHHHHHHCCEEECCCCCCCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHC
IPEHKLRVVAPDVGGGFGTKIFHYQEEAFCTFAAKACNRPVKWTSSRSEAFMSDAHGRDH
CCCCCEEEEECCCCCCCCCEEEEECHHHHHHHHHHHCCCCCEECCCHHHHHHHCCCCCCC
VTKIELALDADNNFTALRTETFANMGAYLSTFAPSIPTWLHGTLMAGNYKTPLVYVNVKA
EEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCCCEEEEEEEE
VFTNTVPVDAYRGAGRPEATFQLERVIDKAALELKVDPVELRRQNFITEFPYATPVAVEY
EEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHEEECCHHHHHHHHCHHCCCCCCCEEEEE
DTGDYHATMDKVLEMSDRAGFEARRKESEARGKLRGFGINCFIEACGIAPSNLVGQLGAR
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCEEEEEEECCCCHHHHHHHHHCC
AGLYESATVRVNATGGLVVMTGSHSHGQGHETSFAQVVADMIGIDENMVEIVHGDTANTP
CCCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCC
MGMGTYGSRSIAVGGSAMVRATEKIIAKAKKIASHLLEASEGDIELKDGAFSVAGTDKSV
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCE
AWGDVTLAAYVPHNYPLEDIEPGLEETAFYDPSNFTYPAGAYTCEVEVDPQTGVVTIERF
EECCEEEEEECCCCCCHHHCCCCHHHHEEECCCCCCCCCCCEEEEEEECCCCCEEEEEHH
ASADDFGNVINPMIVEGQVHGGIAQGIGQALLENCAYDENGQLLTASYMDYTMPRADDLP
CCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCCCC
DMTHYIVDHSCQTPCTHNPLGVKGCGEAGAIGSPPTVINAIVDALRSGGHDVTHIDMPAT
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
PARVWAAMQG
HHHHHEECCC
>Mature Secondary Structure 
PKDGGIGASSKRREDVRFLTGAGNYTDDINIRGQAHVFFLRSDVAHGTLNKVDTTAAEG
CCCCCCCCCCCCCCCEEEEECCCCCCCCEEECCEEEEEEEECCCCCCCCCCCCCHHHCC
MPGVVRVFTGADFEAVGGMPCGWQITDKHGQPMLEPKHPVLAHGKVRHVGEPIAAVVADT
CCCEEEEEECCCHHHCCCCCCCCEEECCCCCCCCCCCCCCEECCCHHHCCCHHHHHHHHH
LEQARDAAEAIELDISELPAVVDMKAAVTDASPKVHDDLPSNLCYDWGFVEENKAATDEA
HHHHHHHHHHHHCCHHHCCHHEECHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHH
FEKAAHVTTLELVNNRLVANPMEPRVAVGDYSRATDDHTLYTTSQNPHVIRLLMGAFVLG
HHHHHHHHHHHHHCCEEECCCCCCCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHC
IPEHKLRVVAPDVGGGFGTKIFHYQEEAFCTFAAKACNRPVKWTSSRSEAFMSDAHGRDH
CCCCCEEEEECCCCCCCCCEEEEECHHHHHHHHHHHCCCCCEECCCHHHHHHHCCCCCCC
VTKIELALDADNNFTALRTETFANMGAYLSTFAPSIPTWLHGTLMAGNYKTPLVYVNVKA
EEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCCCEEEEEEEE
VFTNTVPVDAYRGAGRPEATFQLERVIDKAALELKVDPVELRRQNFITEFPYATPVAVEY
EEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHEEECCHHHHHHHHCHHCCCCCCCEEEEE
DTGDYHATMDKVLEMSDRAGFEARRKESEARGKLRGFGINCFIEACGIAPSNLVGQLGAR
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCEEEEEEECCCCHHHHHHHHHCC
AGLYESATVRVNATGGLVVMTGSHSHGQGHETSFAQVVADMIGIDENMVEIVHGDTANTP
CCCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCC
MGMGTYGSRSIAVGGSAMVRATEKIIAKAKKIASHLLEASEGDIELKDGAFSVAGTDKSV
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCE
AWGDVTLAAYVPHNYPLEDIEPGLEETAFYDPSNFTYPAGAYTCEVEVDPQTGVVTIERF
EECCEEEEEECCCCCCHHHCCCCHHHHEEECCCCCCCCCCCEEEEEEECCCCCEEEEEHH
ASADDFGNVINPMIVEGQVHGGIAQGIGQALLENCAYDENGQLLTASYMDYTMPRADDLP
CCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCCCC
DMTHYIVDHSCQTPCTHNPLGVKGCGEAGAIGSPPTVINAIVDALRSGGHDVTHIDMPAT
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
PARVWAAMQG
HHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]