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The map label for this gene is coxS [H]

Identifier: 110680173

GI number: 110680173

Start: 2852198

End: 2852683

Strand: Reverse

Name: coxS [H]

Synonym: RD1_2974

Alternate gene names: 110680173

Gene position: 2852683-2852198 (Counterclockwise)

Preceding gene: 110680174

Following gene: 110680172

Centisome position: 69.02

GC content: 60.29

Gene sequence:

>486_bases
ATGGCACAGGTCTCAATGACTGTGAACGGCAAAGCCGCGTCCGGCGAAATCGAAGGGCGCACGCTGCTGTCATCGTTTTT
ACGCGATCAACTCAATCTCACCGGCACGCATGTGGGCTGCGACACAAGCCAATGCGGCGCCTGCGTCGTCCATGTGAACG
GTGAGGCGGTCAAGGCCTGCACGATGCTGGCCGCCGAAGCGCAGGGCGCAGAGGTTGCCACCATCGAAGGTGCGGCGAAC
GCCGATGGGTCTTTGAATGTGCTGCAACAGGCATTTCAGGATCACCACGGCTTGCAGTGCGGGTTTTGCACGCCGGGCAT
GGTCATGTCAGCGGCGGCCCTGCTCAAAGAAAACCCCAAGCCGACCGAGGCCGAGGTGCGCGATTACCTTGAGGGCAACA
TCTGCCGCTGCACGGGCTATCATAACATCGTCAAGGCGATCATGGCAGCATCCGGGCAAAGCGTCGACAGCATCGCTGCA
GAATAA

Upstream 100 bases:

>100_bases
CGCCCATGCGACTTAAGTCGATGAAATTAGTGGTTCTCAAGGGGCCATCGTCGTGCTTAACTCAGGCCAAACAAATAACC
AAGCTACTAGGGAGGAAGCC

Downstream 100 bases:

>100_bases
GCATTCATGCGCGTGCCCTGCGTCGGTGGCCTAAGTGCCCCCGCGTATTGCAGCCGCGCCAGCCGGGTGAGGGCAAGCTT
ACCGCAAGTTAAGGGAGAAG

Product: carbon monoxide dehydrogenase, small subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MAQVSMTVNGKAASGEIEGRTLLSSFLRDQLNLTGTHVGCDTSQCGACVVHVNGEAVKACTMLAAEAQGAEVATIEGAAN
ADGSLNVLQQAFQDHHGLQCGFCTPGMVMSAAALLKENPKPTEAEVRDYLEGNICRCTGYHNIVKAIMAASGQSVDSIAA
E

Sequences:

>Translated_161_residues
MAQVSMTVNGKAASGEIEGRTLLSSFLRDQLNLTGTHVGCDTSQCGACVVHVNGEAVKACTMLAAEAQGAEVATIEGAAN
ADGSLNVLQQAFQDHHGLQCGFCTPGMVMSAAALLKENPKPTEAEVRDYLEGNICRCTGYHNIVKAIMAASGQSVDSIAA
E
>Mature_160_residues
AQVSMTVNGKAASGEIEGRTLLSSFLRDQLNLTGTHVGCDTSQCGACVVHVNGEAVKACTMLAAEAQGAEVATIEGAANA
DGSLNVLQQAFQDHHGLQCGFCTPGMVMSAAALLKENPKPTEAEVRDYLEGNICRCTGYHNIVKAIMAASGQSVDSIAAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=150, Percent_Identity=37.3333333333333, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI91823271, Length=150, Percent_Identity=36.6666666666667, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=44.2424242424242, Blast_Score=135, Evalue=1e-33,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=43.5374149659864, Blast_Score=114, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=41.6107382550336, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=165, Percent_Identity=34.5454545454545, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=157, Percent_Identity=35.031847133758, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17737937, Length=149, Percent_Identity=38.255033557047, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24647199, Length=144, Percent_Identity=38.1944444444444, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24647193, Length=150, Percent_Identity=37.3333333333333, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647195, Length=172, Percent_Identity=31.3953488372093, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24647197, Length=172, Percent_Identity=31.3953488372093, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24647201, Length=165, Percent_Identity=32.1212121212121, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16644; Mature: 16513

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVSMTVNGKAASGEIEGRTLLSSFLRDQLNLTGTHVGCDTSQCGACVVHVNGEAVKAC
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEECCCHHHHH
TMLAAEAQGAEVATIEGAANADGSLNVLQQAFQDHHGLQCGFCTPGMVMSAAALLKENPK
HHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCC
PTEAEVRDYLEGNICRCTGYHNIVKAIMAASGQSVDSIAAE
CCHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure 
AQVSMTVNGKAASGEIEGRTLLSSFLRDQLNLTGTHVGCDTSQCGACVVHVNGEAVKAC
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEECCCHHHHH
TMLAAEAQGAEVATIEGAANADGSLNVLQQAFQDHHGLQCGFCTPGMVMSAAALLKENPK
HHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCC
PTEAEVRDYLEGNICRCTGYHNIVKAIMAASGQSVDSIAAE
CCHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]