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The map label for this gene is tpiA [H]

Identifier: 110680160

GI number: 110680160

Start: 2838631

End: 2839377

Strand: Direct

Name: tpiA [H]

Synonym: RD1_2961

Alternate gene names: 110680160

Gene position: 2838631-2839377 (Clockwise)

Preceding gene: 110680159

Following gene: 110680161

Centisome position: 68.68

GC content: 62.25

Gene sequence:

>747_bases
ATGCAGCGTAAACTCGCGGCGGGAAACTGGAAAATGAACGGCACCGTCGCGGACCTGTCCATGATTGACAGCCTGAACAG
CGCGCATCCAAATCCCGGCTGTGAAATTCTGCTCTGCCCCCCTGCGCATCTGTTGTCGCAAGCGGTCGCGCAAGCCCGCA
CAGGACCCGTCCGGATTGGTGCGCAGAATTGCCATTCTGCTGACACCGGCGCTTACACGGGCGATATCTCGGCCCCCATG
CTTGCGGACGTCGGCGCAAGCCATGTCATCGTCGGCCACTCCGAGCGCCGCGAAGGATATGGCGAAACCGATGCAGATGT
GAAGGACAAGGCTGCAGCCGCGCAAGCAGCGGGTCTGACCCCGATCCTATGCATCGGCGAAAGCCTTGAGCAGCGCGAGG
CAGGCGCTGCGCTGGACGTCATACGGGCGCAACTGGCAGGTTCAGTACCCGGCAACAACACCGCCGAGACGCTCGTCGTC
GCCTATGAACCCATATGGGCGATCGGCACCGGCAAAATCCCGACCATGGAAGAGATCGCACAGGTACACGCGGTCCTGCG
TGCAGATCTGATCGACGCACTGGGGACAACCGGTGCCACGGTTCCCCTGCTCTATGGCGGGTCCGTCAAACCGGGCAATG
CGGCCGGAATTTTCGCGCTGGATCATGTGAACGGGGCGCTCGTAGGGGGCGCGAGCCTGACCGCGCAGGATTTCTCTCCC
ATCATCGAAGCACTGTCCGACAGTTGA

Upstream 100 bases:

>100_bases
GGGCAGTTGCAGGATCAGCTAGGCAACACGACGGCACAACAGCATTTGCACCGTTGCACGGCGGCTGTTAGCAAGAAGCA
TCACACAGCAGGAGAACAAG

Downstream 100 bases:

>100_bases
TGGCGCGGCATGTATGGGCGCCAACGCCCTGTGATACATGCGCCGCGCGCCCATGCCTCTACTTTCTCAAGCGGACTTAA
AGGCGGCCATGCAACGACTT

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MQRKLAAGNWKMNGTVADLSMIDSLNSAHPNPGCEILLCPPAHLLSQAVAQARTGPVRIGAQNCHSADTGAYTGDISAPM
LADVGASHVIVGHSERREGYGETDADVKDKAAAAQAAGLTPILCIGESLEQREAGAALDVIRAQLAGSVPGNNTAETLVV
AYEPIWAIGTGKIPTMEEIAQVHAVLRADLIDALGTTGATVPLLYGGSVKPGNAAGIFALDHVNGALVGGASLTAQDFSP
IIEALSDS

Sequences:

>Translated_248_residues
MQRKLAAGNWKMNGTVADLSMIDSLNSAHPNPGCEILLCPPAHLLSQAVAQARTGPVRIGAQNCHSADTGAYTGDISAPM
LADVGASHVIVGHSERREGYGETDADVKDKAAAAQAAGLTPILCIGESLEQREAGAALDVIRAQLAGSVPGNNTAETLVV
AYEPIWAIGTGKIPTMEEIAQVHAVLRADLIDALGTTGATVPLLYGGSVKPGNAAGIFALDHVNGALVGGASLTAQDFSP
IIEALSDS
>Mature_248_residues
MQRKLAAGNWKMNGTVADLSMIDSLNSAHPNPGCEILLCPPAHLLSQAVAQARTGPVRIGAQNCHSADTGAYTGDISAPM
LADVGASHVIVGHSERREGYGETDADVKDKAAAAQAAGLTPILCIGESLEQREAGAALDVIRAQLAGSVPGNNTAETLVV
AYEPIWAIGTGKIPTMEEIAQVHAVLRADLIDALGTTGATVPLLYGGSVKPGNAAGIFALDHVNGALVGGASLTAQDFSP
IIEALSDS

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI226529917, Length=246, Percent_Identity=39.0243902439024, Blast_Score=157, Evalue=9e-39,
Organism=Homo sapiens, GI4507645, Length=246, Percent_Identity=39.0243902439024, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1790353, Length=251, Percent_Identity=39.4422310756972, Blast_Score=170, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17536593, Length=249, Percent_Identity=42.9718875502008, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320255, Length=242, Percent_Identity=40.495867768595, Blast_Score=174, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28572008, Length=251, Percent_Identity=42.6294820717131, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28572006, Length=251, Percent_Identity=42.6294820717131, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28572004, Length=251, Percent_Identity=42.6294820717131, Blast_Score=171, Evalue=4e-43,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25263; Mature: 25263

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRKLAAGNWKMNGTVADLSMIDSLNSAHPNPGCEILLCPPAHLLSQAVAQARTGPVRIG
CCCCCCCCCEEECCEEHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCCCEEEC
AQNCHSADTGAYTGDISAPMLADVGASHVIVGHSERREGYGETDADVKDKAAAAQAAGLT
CCCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHCCCC
PILCIGESLEQREAGAALDVIRAQLAGSVPGNNTAETLVVAYEPIWAIGTGKIPTMEEIA
EEEEECCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEECCCCCCCHHHHH
QVHAVLRADLIDALGTTGATVPLLYGGSVKPGNAAGIFALDHVNGALVGGASLTAQDFSP
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHH
IIEALSDS
HHHHHCCC
>Mature Secondary Structure
MQRKLAAGNWKMNGTVADLSMIDSLNSAHPNPGCEILLCPPAHLLSQAVAQARTGPVRIG
CCCCCCCCCEEECCEEHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCCCEEEC
AQNCHSADTGAYTGDISAPMLADVGASHVIVGHSERREGYGETDADVKDKAAAAQAAGLT
CCCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHCCCC
PILCIGESLEQREAGAALDVIRAQLAGSVPGNNTAETLVVAYEPIWAIGTGKIPTMEEIA
EEEEECCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEECCCCCCCHHHHH
QVHAVLRADLIDALGTTGATVPLLYGGSVKPGNAAGIFALDHVNGALVGGASLTAQDFSP
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHH
IIEALSDS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA