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The map label for this gene is uxaC [H]

Identifier: 110680135

GI number: 110680135

Start: 2813213

End: 2814619

Strand: Reverse

Name: uxaC [H]

Synonym: RD1_2934

Alternate gene names: 110680135

Gene position: 2814619-2813213 (Counterclockwise)

Preceding gene: 110680136

Following gene: 110680134

Centisome position: 68.1

GC content: 60.91

Gene sequence:

>1407_bases
ATGGGCCTGACTGATCCCGAACGATTGTTTCCGATTGAGCCATCGGCAAGAGCCTTGGCGCGTGGCCTTTACGCCTCTGT
TTGTGATCTGCCGATCATCAGCCCGCATGGCCATTGTGACCCGCGCTGGTTCGCCGAAAATCAACGGTTTGAAAACCCGG
CGGCCCTGTTCGTGATCCCTGATCACTATGTGTTTCGCATGTTGATCAGTCAGGGCGTCGCGCCTGAGGATCTGGGCATA
CCGCGTGTTGACGGGGGCGAGGTCGAAACCGACCCGCGCAAGATATGGCGTTTGTTTGCGCAGCACTTCCATCTCTTTCG
CGGCACGCCTTCGGCGATGTGGCTGAACCATTCCTTTGAGCATGTCTTTGATCTCACCACACCGCTGAGCGGCGAAACAG
CGGATGCATGCTATGATCATATCGAGGCCAAGCTGCAAACGGATGCGTTCCGCCCTCGCGCGCTGTTCGAGCGTTTCAAT
GTTGAGGTGCTTGCCACCACCGAAGGGGCGCTGGACGATCTGCGCTGGCACCGCGAAATCCGGGACAGCGGCTGGTCGGG
CCGGGTGGTGACCACCTACAGGCCGGACGCGGTGGTGGATCCGGCGTTTGAGGGCTTCGCGGAAAACGTCGCGCAGCTGG
GGGCGCTGACCGGCGAGGACACAAGCACCTGGCAGGGGTATCTGAATGCACATGCGGCGCGTCGGGCGTTTTTCAAATCA
CTCGGCGCCACGGCCTCGGATCACGGTCATCCTTCGGCACGCACCGCCGATCTGCCACAGGCAGAGGCGGCTGCGCTGTT
CCAAAAGGCGCTGAGCGGGCAGTGTTCCCCCGAGGAGCAAGATGTGTTTCGCGGCCATATGTTGACCGAAATGGCGCGGA
TGAGCCTTGAGGACGGGCTTGTGCTGCAAATCCATCCCGGGTCGCGCCGCAACCACAGTGCGCAGATGTTCGCGCGCTTT
GGCCGGGACAAGGGGTTCGATATCCCCGGTCGCACGGATTACGTGCAGGATCTGCGCCCTCTGCTGGATGCGGTCGGCAT
GGAACCTGCGCTGAACATCATTCTGTTCACGCTGGATGAGACCACATACAGCCGCGAACTGGCACCACTCGCGGGGGCTT
ATCCGGCGCTGAAACTAGGGCCGCCCTGGTGGTTTTTTGACAGCTATGAGGGGATCAAGCGCTTCCGCGAAACCACGACC
GAAACCTGCGGGTTTTACAACACGGCCGGGTTCAATGACGATACGCGTGCGTTCTGTTCCATTCCCGCACGTCACGATGT
GGCGCGCCGCTCGGACTGTGCCTATCTGGCGACGCTGGTCAGGACGGGTCGGCTGACAGAGGCCGAAGCCTTGGATCTGG
CCTATGATCTGACCTACCGTCTGGCAAAGGAGGCCTATCGGTTATGA

Upstream 100 bases:

>100_bases
CAGCGTTATTTTTTCCATGCCCTTGCCGACAGCAAGGACTCTTTCTAAAGCCTGATTACTGACCTATCACTGCGGTGACG
CACTATTTGAGGACAAGCAT

Downstream 100 bases:

>100_bases
CCATGCCACCCCGCTTGCAACGCCAGAACAAAGCGCCAGGGATCGGCATGGTCCACCTTGGCCCGGGTGCGTTCTTCCGC
GCGTTTAACGCCGTCTATAC

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MGLTDPERLFPIEPSARALARGLYASVCDLPIISPHGHCDPRWFAENQRFENPAALFVIPDHYVFRMLISQGVAPEDLGI
PRVDGGEVETDPRKIWRLFAQHFHLFRGTPSAMWLNHSFEHVFDLTTPLSGETADACYDHIEAKLQTDAFRPRALFERFN
VEVLATTEGALDDLRWHREIRDSGWSGRVVTTYRPDAVVDPAFEGFAENVAQLGALTGEDTSTWQGYLNAHAARRAFFKS
LGATASDHGHPSARTADLPQAEAAALFQKALSGQCSPEEQDVFRGHMLTEMARMSLEDGLVLQIHPGSRRNHSAQMFARF
GRDKGFDIPGRTDYVQDLRPLLDAVGMEPALNIILFTLDETTYSRELAPLAGAYPALKLGPPWWFFDSYEGIKRFRETTT
ETCGFYNTAGFNDDTRAFCSIPARHDVARRSDCAYLATLVRTGRLTEAEALDLAYDLTYRLAKEAYRL

Sequences:

>Translated_468_residues
MGLTDPERLFPIEPSARALARGLYASVCDLPIISPHGHCDPRWFAENQRFENPAALFVIPDHYVFRMLISQGVAPEDLGI
PRVDGGEVETDPRKIWRLFAQHFHLFRGTPSAMWLNHSFEHVFDLTTPLSGETADACYDHIEAKLQTDAFRPRALFERFN
VEVLATTEGALDDLRWHREIRDSGWSGRVVTTYRPDAVVDPAFEGFAENVAQLGALTGEDTSTWQGYLNAHAARRAFFKS
LGATASDHGHPSARTADLPQAEAAALFQKALSGQCSPEEQDVFRGHMLTEMARMSLEDGLVLQIHPGSRRNHSAQMFARF
GRDKGFDIPGRTDYVQDLRPLLDAVGMEPALNIILFTLDETTYSRELAPLAGAYPALKLGPPWWFFDSYEGIKRFRETTT
ETCGFYNTAGFNDDTRAFCSIPARHDVARRSDCAYLATLVRTGRLTEAEALDLAYDLTYRLAKEAYRL
>Mature_467_residues
GLTDPERLFPIEPSARALARGLYASVCDLPIISPHGHCDPRWFAENQRFENPAALFVIPDHYVFRMLISQGVAPEDLGIP
RVDGGEVETDPRKIWRLFAQHFHLFRGTPSAMWLNHSFEHVFDLTTPLSGETADACYDHIEAKLQTDAFRPRALFERFNV
EVLATTEGALDDLRWHREIRDSGWSGRVVTTYRPDAVVDPAFEGFAENVAQLGALTGEDTSTWQGYLNAHAARRAFFKSL
GATASDHGHPSARTADLPQAEAAALFQKALSGQCSPEEQDVFRGHMLTEMARMSLEDGLVLQIHPGSRRNHSAQMFARFG
RDKGFDIPGRTDYVQDLRPLLDAVGMEPALNIILFTLDETTYSRELAPLAGAYPALKLGPPWWFFDSYEGIKRFRETTTE
TCGFYNTAGFNDDTRAFCSIPARHDVARRSDCAYLATLVRTGRLTEAEALDLAYDLTYRLAKEAYRL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=436, Percent_Identity=27.2935779816514, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 52524; Mature: 52393

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTDPERLFPIEPSARALARGLYASVCDLPIISPHGHCDPRWFAENQRFENPAALFVIP
CCCCCCHHEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
DHYVFRMLISQGVAPEDLGIPRVDGGEVETDPRKIWRLFAQHFHLFRGTPSAMWLNHSFE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCHH
HVFDLTTPLSGETADACYDHIEAKLQTDAFRPRALFERFNVEVLATTEGALDDLRWHREI
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHH
RDSGWSGRVVTTYRPDAVVDPAFEGFAENVAQLGALTGEDTSTWQGYLNAHAARRAFFKS
HCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LGATASDHGHPSARTADLPQAEAAALFQKALSGQCSPEEQDVFRGHMLTEMARMSLEDGL
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCE
VLQIHPGSRRNHSAQMFARFGRDKGFDIPGRTDYVQDLRPLLDAVGMEPALNIILFTLDE
EEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECC
TTYSRELAPLAGAYPALKLGPPWWFFDSYEGIKRFRETTTETCGFYNTAGFNDDTRAFCS
CHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEC
IPARHDVARRSDCAYLATLVRTGRLTEAEALDLAYDLTYRLAKEAYRL
CCCHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLTDPERLFPIEPSARALARGLYASVCDLPIISPHGHCDPRWFAENQRFENPAALFVIP
CCCCCHHEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
DHYVFRMLISQGVAPEDLGIPRVDGGEVETDPRKIWRLFAQHFHLFRGTPSAMWLNHSFE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCHH
HVFDLTTPLSGETADACYDHIEAKLQTDAFRPRALFERFNVEVLATTEGALDDLRWHREI
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHH
RDSGWSGRVVTTYRPDAVVDPAFEGFAENVAQLGALTGEDTSTWQGYLNAHAARRAFFKS
HCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LGATASDHGHPSARTADLPQAEAAALFQKALSGQCSPEEQDVFRGHMLTEMARMSLEDGL
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCE
VLQIHPGSRRNHSAQMFARFGRDKGFDIPGRTDYVQDLRPLLDAVGMEPALNIILFTLDE
EEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECC
TTYSRELAPLAGAYPALKLGPPWWFFDSYEGIKRFRETTTETCGFYNTAGFNDDTRAFCS
CHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEC
IPARHDVARRSDCAYLATLVRTGRLTEAEALDLAYDLTYRLAKEAYRL
CCCHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]