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The map label for this gene is kdgR [H]

Identifier: 110680066

GI number: 110680066

Start: 2730131

End: 2730922

Strand: Reverse

Name: kdgR [H]

Synonym: RD1_2861

Alternate gene names: 110680066

Gene position: 2730922-2730131 (Counterclockwise)

Preceding gene: 110680075

Following gene: 110680065

Centisome position: 66.07

GC content: 60.86

Gene sequence:

>792_bases
ATGTCCGGGGATGGAACGGTAGGCAAGGCACTTGATGTGCTGGATCAGGTGGCAGAGTTTGGCCAGCCTGTGCGCTTTGC
CACCTTGCTGGCGCAGAGCCAGTTTCCCAAGGCCACGCTTTATCGGTTTTTGCAAACGCTCACATCGCAAGGCATGCTGG
CTTATGACCCTGAGCGTCAGACCTACAGCCTGGGCGTGCGTCTGGTGCGGCTTGCCCATGCGGCATGGGCGCAGAGTTCA
CTGGCACCGATTGCGCGCCCCCATCTTGACCGGCTGAGCGCCGAGATTGACCAGACGGTGCATCTGGCACAACTGGACAA
TGCGCAGGTGCTCTACGTGGACAAGCGCAATGCGGCCCAACCGGTCGAGATGTTCAGCGATGCAGGCAAGGTCGGGCCGG
CCTATTGCACGGGCGTGGGCAAGGCGATGCTGGCCTTCCTGCCGTCTGCGGATCTGGACAGGGTGATCGCGCAGCAGTCG
TTTCACCGTTTTACCCCCAATACATATACCTGCGCTGAAACACTTTGCGCGGAATTGGGTCGCATCCGGGCGCGCGGCTA
TGCCTTTGATCGCGAAGAGCATGAACCCGGCATTATTTGCATCGCGCATCCGATCCTTGCGCCGGGGGGGCGGGTGTTGG
GCGCTTTGTCGATCACGGGGTCCACGCGGATCATCTCACTGGATCAGTTGGAGGCGCTCGCGCCATGTCTTGCGCGGACT
GCCACTGCCATTGCAGCGGATGTGCAGGACTGGCGCTTTCCCGATGCAAAGCCACAAATGACAGGGACGTAA

Upstream 100 bases:

>100_bases
GAACATGCGGCATAGTATGGGGCAGATGCCCCTGCGCCAATCAGGTGGCACAGCGATTTTGCCTTGTGCCACAGACAGAT
GAGGGGGGGACCGGCTGGGC

Downstream 100 bases:

>100_bases
CCATATGACAGGTGTCACGCTTCAGAAAACGATCAAACGCTATGGTGAAACGCAGGTGATCCATGGGATTGATCTGGAAA
TCAAGGACGGTGAATTCTGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSGDGTVGKALDVLDQVAEFGQPVRFATLLAQSQFPKATLYRFLQTLTSQGMLAYDPERQTYSLGVRLVRLAHAAWAQSS
LAPIARPHLDRLSAEIDQTVHLAQLDNAQVLYVDKRNAAQPVEMFSDAGKVGPAYCTGVGKAMLAFLPSADLDRVIAQQS
FHRFTPNTYTCAETLCAELGRIRARGYAFDREEHEPGIICIAHPILAPGGRVLGALSITGSTRIISLDQLEALAPCLART
ATAIAADVQDWRFPDAKPQMTGT

Sequences:

>Translated_263_residues
MSGDGTVGKALDVLDQVAEFGQPVRFATLLAQSQFPKATLYRFLQTLTSQGMLAYDPERQTYSLGVRLVRLAHAAWAQSS
LAPIARPHLDRLSAEIDQTVHLAQLDNAQVLYVDKRNAAQPVEMFSDAGKVGPAYCTGVGKAMLAFLPSADLDRVIAQQS
FHRFTPNTYTCAETLCAELGRIRARGYAFDREEHEPGIICIAHPILAPGGRVLGALSITGSTRIISLDQLEALAPCLART
ATAIAADVQDWRFPDAKPQMTGT
>Mature_262_residues
SGDGTVGKALDVLDQVAEFGQPVRFATLLAQSQFPKATLYRFLQTLTSQGMLAYDPERQTYSLGVRLVRLAHAAWAQSSL
APIARPHLDRLSAEIDQTVHLAQLDNAQVLYVDKRNAAQPVEMFSDAGKVGPAYCTGVGKAMLAFLPSADLDRVIAQQSF
HRFTPNTYTCAETLCAELGRIRARGYAFDREEHEPGIICIAHPILAPGGRVLGALSITGSTRIISLDQLEALAPCLARTA
TAIAADVQDWRFPDAKPQMTGT

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=249, Percent_Identity=30.1204819277108, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786468, Length=214, Percent_Identity=31.3084112149533, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1788581, Length=249, Percent_Identity=30.5220883534137, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082359, Length=241, Percent_Identity=26.1410788381743, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790752, Length=244, Percent_Identity=26.2295081967213, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789999, Length=255, Percent_Identity=28.2352941176471, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786715, Length=237, Percent_Identity=24.8945147679325, Blast_Score=87, Evalue=8e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28496; Mature: 28365

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDGTVGKALDVLDQVAEFGQPVRFATLLAQSQFPKATLYRFLQTLTSQGMLAYDPERQ
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCH
TYSLGVRLVRLAHAAWAQSSLAPIARPHLDRLSAEIDQTVHLAQLDNAQVLYVDKRNAAQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCC
PVEMFSDAGKVGPAYCTGVGKAMLAFLPSADLDRVIAQQSFHRFTPNTYTCAETLCAELG
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RIRARGYAFDREEHEPGIICIAHPILAPGGRVLGALSITGSTRIISLDQLEALAPCLART
HHHHCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHH
ATAIAADVQDWRFPDAKPQMTGT
HHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SGDGTVGKALDVLDQVAEFGQPVRFATLLAQSQFPKATLYRFLQTLTSQGMLAYDPERQ
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCH
TYSLGVRLVRLAHAAWAQSSLAPIARPHLDRLSAEIDQTVHLAQLDNAQVLYVDKRNAAQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCC
PVEMFSDAGKVGPAYCTGVGKAMLAFLPSADLDRVIAQQSFHRFTPNTYTCAETLCAELG
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RIRARGYAFDREEHEPGIICIAHPILAPGGRVLGALSITGSTRIISLDQLEALAPCLART
HHHHCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHH
ATAIAADVQDWRFPDAKPQMTGT
HHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]