Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 110680075

GI number: 110680075

Start: 2740877

End: 2742508

Strand: Reverse

Name: pgm [H]

Synonym: RD1_2870

Alternate gene names: 110680075

Gene position: 2742508-2740877 (Counterclockwise)

Preceding gene: 110680076

Following gene: 110680066

Centisome position: 66.35

GC content: 60.97

Gene sequence:

>1632_bases
ATGACCCTGTCGACCATCAAAAAAGGCCCTTTTGAGGGTCAGAAGCCCGGCACCTCGGGGCTGCGCAAGAAAACGCGGGT
GTTTATGGAGCCGGGGTATCTGGAGTGTTTCGTCCAGTCGACGTTCAACGCGATCGGCGGTGTTGCGGGCAAATCACTGG
TCATCGGGGGCGATGGCCGATTTTACAATGACAAGGCGATCCAGATCATCCTGAAAATGGCCGCCGCCAATGGCGCGGCA
TTGGCGGTTGTCGGGCAGGGTGGGTTGCTGTCGACACCTGCGGTGTCGCACCTGATCCGCAAGCGGAAAACCGACGGCGG
TCTGATCCTGTCGGCCAGCCACAACCCCGGCGGCATCGATGAGGATTTCGGGATCAAGTATAACGTCGCCAATGGTGGCC
CCGCTCCTGAATCCGTAACGGCGCGCATGTTTGACGAAACGCTCAAGATCACGGAATACAGAACAATCGACGCGCCGGAC
ATTGCGCTTGGCGATCTGGGCCTGCACCAGATCGGCGAGATGCAGGTGGAGATCATTGACCCGGTTGCAGATTATGCTGC
GCTGATGGAAACCCTGTTTGATTTTGGCAAGATCAAAGCGCTGTTTGCGGGCGGGTTCATGATGCGCTTTGATGCGATGC
ACGCCGTCACCGGCCCCTATGCCAAGGCCATTCTGGAGGACCGGCTTGGCGCGCCTGCCGGAACGGTCATCAACGCGGTC
CCGAGCGAGGATTTTGGCGGCGGGCATCCTGATCCCAATCCGGTCTGGGCCAAGGCGCTGATGGAGGAGATGATGTCGCC
CACAGCCCCCGATTTCGGCGCGGCTTCGGACGGGGACGGGGATCGCAACATGATTGTCGGGCGCGGCAGCTATGTGACGC
CCTCGGACAGTCTTGCGGTTCTGGCGGCCAATGCGCATCTGGCTCCGGCCTATGAGGCAGGGCTTGCGGGGGTTGCCCGT
TCCATGCCCACCAGTGCCGCCAGTGATCTTGTGGCGCAAAAGTTGGGGATCAACAGTTTCGAGACACCCACCGGGTGGAA
ATTCTTTGGCAACCTGTTGGATGCGGGCAAGGTGACGCTCTGCGGTGAAGAGAGCGCGGGCACCGGATCAGATCACGTGC
GCGAAAAGGATGGCCTATGGGCGGTGTTGCTCTGGCTGAATATTCTTGCGCAGCGCAAGCAATCGGTGGCGGATATTCTC
GTGGATCACTGGGCGGAATACGGCCGCAACTATTATTCACGCCATGATTATGAGGCCGTTCCGACAGAGGCGGCCAACGC
CCTGATGGCGCATCTTGAAGCACAGTTTGACAGCTTGCCGGGCACGCAGTGGTCGGGGCTGAGCGTGCGTGCGGCGGATA
GCTTCTCCTATCATGACCCGGTCGATGGGTCGGTCAGTGAAAATCAGGGGTTGCGGATCAGCTTTGAGGGCGGCGCGCGC
GCCGTTTTGCGCCTGTCGGGCACGGGCACGGAAGGTGCGACACTGCGCGTCTATCTGGAGCAATACGCAGGCCCGGATGC
CGATAATTCCCTCACCGCCGAGGCTGCGCTGGCCTCGGTACGCGCGGCGGTGATCGAGATCACGGCCATGCAATCCCACA
TCGGTCGCACAGCACCGGATGTGCGCACCTGA

Upstream 100 bases:

>100_bases
CGGTGCGCGGGCAGGCTCTGGCCAAGGACAAGGCACTGCAGGCCACAAGCCTGATCATGGCGCGCGCCGCGCGAAATACC
GCAGAACGAAAGGACGAGCG

Downstream 100 bases:

>100_bases
TGCGTCAGCGCCGGGCCCAAGCCACGCCAGCAGCGGGCAGGCTCAGCCCGTCAAACGCACAGGGCGTGGCGGCGTAGTTG
AAATAGAACCGGTGCGTTTT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MTLSTIKKGPFEGQKPGTSGLRKKTRVFMEPGYLECFVQSTFNAIGGVAGKSLVIGGDGRFYNDKAIQIILKMAAANGAA
LAVVGQGGLLSTPAVSHLIRKRKTDGGLILSASHNPGGIDEDFGIKYNVANGGPAPESVTARMFDETLKITEYRTIDAPD
IALGDLGLHQIGEMQVEIIDPVADYAALMETLFDFGKIKALFAGGFMMRFDAMHAVTGPYAKAILEDRLGAPAGTVINAV
PSEDFGGGHPDPNPVWAKALMEEMMSPTAPDFGAASDGDGDRNMIVGRGSYVTPSDSLAVLAANAHLAPAYEAGLAGVAR
SMPTSAASDLVAQKLGINSFETPTGWKFFGNLLDAGKVTLCGEESAGTGSDHVREKDGLWAVLLWLNILAQRKQSVADIL
VDHWAEYGRNYYSRHDYEAVPTEAANALMAHLEAQFDSLPGTQWSGLSVRAADSFSYHDPVDGSVSENQGLRISFEGGAR
AVLRLSGTGTEGATLRVYLEQYAGPDADNSLTAEAALASVRAAVIEITAMQSHIGRTAPDVRT

Sequences:

>Translated_543_residues
MTLSTIKKGPFEGQKPGTSGLRKKTRVFMEPGYLECFVQSTFNAIGGVAGKSLVIGGDGRFYNDKAIQIILKMAAANGAA
LAVVGQGGLLSTPAVSHLIRKRKTDGGLILSASHNPGGIDEDFGIKYNVANGGPAPESVTARMFDETLKITEYRTIDAPD
IALGDLGLHQIGEMQVEIIDPVADYAALMETLFDFGKIKALFAGGFMMRFDAMHAVTGPYAKAILEDRLGAPAGTVINAV
PSEDFGGGHPDPNPVWAKALMEEMMSPTAPDFGAASDGDGDRNMIVGRGSYVTPSDSLAVLAANAHLAPAYEAGLAGVAR
SMPTSAASDLVAQKLGINSFETPTGWKFFGNLLDAGKVTLCGEESAGTGSDHVREKDGLWAVLLWLNILAQRKQSVADIL
VDHWAEYGRNYYSRHDYEAVPTEAANALMAHLEAQFDSLPGTQWSGLSVRAADSFSYHDPVDGSVSENQGLRISFEGGAR
AVLRLSGTGTEGATLRVYLEQYAGPDADNSLTAEAALASVRAAVIEITAMQSHIGRTAPDVRT
>Mature_542_residues
TLSTIKKGPFEGQKPGTSGLRKKTRVFMEPGYLECFVQSTFNAIGGVAGKSLVIGGDGRFYNDKAIQIILKMAAANGAAL
AVVGQGGLLSTPAVSHLIRKRKTDGGLILSASHNPGGIDEDFGIKYNVANGGPAPESVTARMFDETLKITEYRTIDAPDI
ALGDLGLHQIGEMQVEIIDPVADYAALMETLFDFGKIKALFAGGFMMRFDAMHAVTGPYAKAILEDRLGAPAGTVINAVP
SEDFGGGHPDPNPVWAKALMEEMMSPTAPDFGAASDGDGDRNMIVGRGSYVTPSDSLAVLAANAHLAPAYEAGLAGVARS
MPTSAASDLVAQKLGINSFETPTGWKFFGNLLDAGKVTLCGEESAGTGSDHVREKDGLWAVLLWLNILAQRKQSVADILV
DHWAEYGRNYYSRHDYEAVPTEAANALMAHLEAQFDSLPGTQWSGLSVRAADSFSYHDPVDGSVSENQGLRISFEGGARA
VLRLSGTGTEGATLRVYLEQYAGPDADNSLTAEAALASVRAAVIEITAMQSHIGRTAPDVRT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=562, Percent_Identity=53.7366548042705, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI21361621, Length=562, Percent_Identity=52.3131672597865, Blast_Score=564, Evalue=1e-161,
Organism=Homo sapiens, GI133922562, Length=559, Percent_Identity=46.8694096601073, Blast_Score=488, Evalue=1e-138,
Organism=Homo sapiens, GI290463104, Length=366, Percent_Identity=54.9180327868852, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI239743670, Length=134, Percent_Identity=41.7910447761194, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI239741729, Length=134, Percent_Identity=40.2985074626866, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1786904, Length=424, Percent_Identity=28.3018867924528, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17535441, Length=559, Percent_Identity=50.2683363148479, Blast_Score=528, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6323752, Length=571, Percent_Identity=47.4605954465849, Blast_Score=498, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6322722, Length=561, Percent_Identity=47.7718360071301, Blast_Score=493, Evalue=1e-140,
Organism=Drosophila melanogaster, GI17864244, Length=562, Percent_Identity=47.864768683274, Blast_Score=526, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 57372; Mature: 57241

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSTIKKGPFEGQKPGTSGLRKKTRVFMEPGYLECFVQSTFNAIGGVAGKSLVIGGDGR
CCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCC
FYNDKAIQIILKMAAANGAALAVVGQGGLLSTPAVSHLIRKRKTDGGLILSASHNPGGID
EECHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCC
EDFGIKYNVANGGPAPESVTARMFDETLKITEYRTIDAPDIALGDLGLHQIGEMQVEIID
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCEECCCCHHHHCCEEEEEEC
PVADYAALMETLFDFGKIKALFAGGFMMRFDAMHAVTGPYAKAILEDRLGAPAGTVINAV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEECC
PSEDFGGGHPDPNPVWAKALMEEMMSPTAPDFGAASDGDGDRNMIVGRGSYVTPSDSLAV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCEECCCCCEEE
LAANAHLAPAYEAGLAGVARSMPTSAASDLVAQKLGINSFETPTGWKFFGNLLDAGKVTL
EEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEE
CGEESAGTGSDHVREKDGLWAVLLWLNILAQRKQSVADILVDHWAEYGRNYYSRHDYEAV
ECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
PTEAANALMAHLEAQFDSLPGTQWSGLSVRAADSFSYHDPVDGSVSENQGLRISFEGGAR
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCE
AVLRLSGTGTEGATLRVYLEQYAGPDADNSLTAEAALASVRAAVIEITAMQSHIGRTAPD
EEEEEECCCCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VRT
CCC
>Mature Secondary Structure 
TLSTIKKGPFEGQKPGTSGLRKKTRVFMEPGYLECFVQSTFNAIGGVAGKSLVIGGDGR
CCCCCCCCCCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCC
FYNDKAIQIILKMAAANGAALAVVGQGGLLSTPAVSHLIRKRKTDGGLILSASHNPGGID
EECHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCC
EDFGIKYNVANGGPAPESVTARMFDETLKITEYRTIDAPDIALGDLGLHQIGEMQVEIID
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCEECCCCHHHHCCEEEEEEC
PVADYAALMETLFDFGKIKALFAGGFMMRFDAMHAVTGPYAKAILEDRLGAPAGTVINAV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEECC
PSEDFGGGHPDPNPVWAKALMEEMMSPTAPDFGAASDGDGDRNMIVGRGSYVTPSDSLAV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCEECCCCCEEE
LAANAHLAPAYEAGLAGVARSMPTSAASDLVAQKLGINSFETPTGWKFFGNLLDAGKVTL
EEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEE
CGEESAGTGSDHVREKDGLWAVLLWLNILAQRKQSVADILVDHWAEYGRNYYSRHDYEAV
ECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
PTEAANALMAHLEAQFDSLPGTQWSGLSVRAADSFSYHDPVDGSVSENQGLRISFEGGAR
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCE
AVLRLSGTGTEGATLRVYLEQYAGPDADNSLTAEAALASVRAAVIEITAMQSHIGRTAPD
EEEEEECCCCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VRT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]