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The map label for this gene is metA

Identifier: 110679994

GI number: 110679994

Start: 2654541

End: 2655458

Strand: Direct

Name: metA

Synonym: RD1_2784

Alternate gene names: 110679994

Gene position: 2654541-2655458 (Clockwise)

Preceding gene: 110679993

Following gene: 110679995

Centisome position: 64.23

GC content: 56.64

Gene sequence:

>918_bases
ATGCCGATCAAGATACCTGCCGACCTTCCTGCCTATGACGTGCTGACGCGCGAAGGCGTGATGGTCATGGATCCGGATCA
GGCGGCGCGTCAGGATATCCGCCCGCTGCGCATCGGGCTGTTGAACCTGATGCCCAAGAAAATTCAGACCGAGAACCAGT
TTGCCCGCCTGATCGGCGCAACCCCCCTGCAGATCGAACTGAGCCTGATCCGTATGTCCGAGCATCAGACGAAAAACACC
GCTGCAGAACATATGGAAAGCTTCTACCGCCCCTTTCAGGACATCAAGTCGGAAAAGTTCGACGGGTTGATCATCACTGG
TGCACCCATTGAACATCTGGATTTTCAAGATGTTACCTATTGGGATGAGCTGCGAGAGGTCATGGACTGGACACAAACCA
ACGTGCATTCCACCTTTGGCGTGTGCTGGGGCGGCATGGCCATGATCAATCACTTTCACGGCGTGCGCAAACACATGCTG
GAGGCCAAGGCCTTCGGTTGCTTCAGACATCGCAACCTTGCACCGGCATCCCCCTACCTGCGCGGATTTTCGGATGAATG
CGTGATCCCCGTCTCCCGCTGGACCGAGATGCGACAAAGTGAAATCGACGCCGCCGAGGGGCTGAAGACGCTGTTGGGCA
GTGATCAGGTCGGGCCCTGCCTCGTGCAGGACAAGGCGCACCGTGCGCTCTATATCTTCAATCACTTTGAATACGACAGC
GAAACGCTCAAGCAGGAGTACGACCGTGATGTGGCGGCAGGGAACCAGATCAACGTGCCGCTGAATTATTACCCGGATGA
TGACCCGTCGCGCGCGCCGCTGAACCGCTGGCGCAGCCATGCCCATCTGCTTTATGGCAACTGGTTGACGGAGATCTACC
AAGACACGCCCTATGACATTGATGCCATTGGCCGTTAA

Upstream 100 bases:

>100_bases
TGCCTCTGAGCGTTTCACCGCCTCGTGACATGGCCCCCCTTGAGAGTTTGACGCACAAGGGCTAAGTGCACTTCCTCATC
CAGACAGCGGAAAAACCCAA

Downstream 100 bases:

>100_bases
ATCGCTCATCATCCTCACCCTGCTGTGCCTTGGGCTCGCCGTCCTTGTGCAATGGCGGGCAAGTGCGCGTGAAACTGCGG
TGGAGGCGCAATATCCACCC

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPIKIPADLPAYDVLTREGVMVMDPDQAARQDIRPLRIGLLNLMPKKIQTENQFARLIGATPLQIELSLIRMSEHQTKNT
AAEHMESFYRPFQDIKSEKFDGLIITGAPIEHLDFQDVTYWDELREVMDWTQTNVHSTFGVCWGGMAMINHFHGVRKHML
EAKAFGCFRHRNLAPASPYLRGFSDECVIPVSRWTEMRQSEIDAAEGLKTLLGSDQVGPCLVQDKAHRALYIFNHFEYDS
ETLKQEYDRDVAAGNQINVPLNYYPDDDPSRAPLNRWRSHAHLLYGNWLTEIYQDTPYDIDAIGR

Sequences:

>Translated_305_residues
MPIKIPADLPAYDVLTREGVMVMDPDQAARQDIRPLRIGLLNLMPKKIQTENQFARLIGATPLQIELSLIRMSEHQTKNT
AAEHMESFYRPFQDIKSEKFDGLIITGAPIEHLDFQDVTYWDELREVMDWTQTNVHSTFGVCWGGMAMINHFHGVRKHML
EAKAFGCFRHRNLAPASPYLRGFSDECVIPVSRWTEMRQSEIDAAEGLKTLLGSDQVGPCLVQDKAHRALYIFNHFEYDS
ETLKQEYDRDVAAGNQINVPLNYYPDDDPSRAPLNRWRSHAHLLYGNWLTEIYQDTPYDIDAIGR
>Mature_304_residues
PIKIPADLPAYDVLTREGVMVMDPDQAARQDIRPLRIGLLNLMPKKIQTENQFARLIGATPLQIELSLIRMSEHQTKNTA
AEHMESFYRPFQDIKSEKFDGLIITGAPIEHLDFQDVTYWDELREVMDWTQTNVHSTFGVCWGGMAMINHFHGVRKHMLE
AKAFGCFRHRNLAPASPYLRGFSDECVIPVSRWTEMRQSEIDAAEGLKTLLGSDQVGPCLVQDKAHRALYIFNHFEYDSE
TLKQEYDRDVAAGNQINVPLNYYPDDDPSRAPLNRWRSHAHLLYGNWLTEIYQDTPYDIDAIGR

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family

Homologues:

Organism=Escherichia coli, GI1790443, Length=301, Percent_Identity=42.5249169435216, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): META_ROSDO (Q165M8)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683001.1
- ProteinModelPortal:   Q165M8
- SMR:   Q165M8
- STRING:   Q165M8
- GeneID:   4195535
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2784
- NMPDR:   fig|375451.6.peg.2582
- eggNOG:   COG1897
- HOGENOM:   HBG362506
- OMA:   QAGLYYH
- PhylomeDB:   Q165M8
- ProtClustDB:   PRK05368
- BioCyc:   RDEN375451:RD1_2784-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00295
- InterPro:   IPR005697
- PANTHER:   PTHR20919
- PIRSF:   PIRSF000450
- ProDom:   PD037892
- TIGRFAMs:   TIGR01001

Pfam domain/function: PF04204 HTS

EC number: =2.3.1.46

Molecular weight: Translated: 35109; Mature: 34978

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKIPADLPAYDVLTREGVMVMDPDQAARQDIRPLRIGLLNLMPKKIQTENQFARLIGA
CCCCCCCCCCHHHHHHCCCEEEECCCHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCC
TPLQIELSLIRMSEHQTKNTAAEHMESFYRPFQDIKSEKFDGLIITGAPIEHLDFQDVTY
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHH
WDELREVMDWTQTNVHSTFGVCWGGMAMINHFHGVRKHMLEAKAFGCFRHRNLAPASPYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RGFSDECVIPVSRWTEMRQSEIDAAEGLKTLLGSDQVGPCLVQDKAHRALYIFNHFEYDS
HCCCCCEEEEHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCH
ETLKQEYDRDVAAGNQINVPLNYYPDDDPSRAPLNRWRSHAHLLYGNWLTEIYQDTPYDI
HHHHHHHHHHHHCCCEEECCEECCCCCCCCCCHHHHHHHHHEEHHHHHHHHHHCCCCCCC
DAIGR
CCCCC
>Mature Secondary Structure 
PIKIPADLPAYDVLTREGVMVMDPDQAARQDIRPLRIGLLNLMPKKIQTENQFARLIGA
CCCCCCCCCHHHHHHCCCEEEECCCHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCC
TPLQIELSLIRMSEHQTKNTAAEHMESFYRPFQDIKSEKFDGLIITGAPIEHLDFQDVTY
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHH
WDELREVMDWTQTNVHSTFGVCWGGMAMINHFHGVRKHMLEAKAFGCFRHRNLAPASPYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RGFSDECVIPVSRWTEMRQSEIDAAEGLKTLLGSDQVGPCLVQDKAHRALYIFNHFEYDS
HCCCCCEEEEHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCH
ETLKQEYDRDVAAGNQINVPLNYYPDDDPSRAPLNRWRSHAHLLYGNWLTEIYQDTPYDI
HHHHHHHHHHHHCCCEEECCEECCCCCCCCCCHHHHHHHHHEEHHHHHHHHHHCCCCCCC
DAIGR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA