Click here to switch to the map view.

The map label for this gene is trkH-2 [H]

Identifier: 110679967

GI number: 110679967

Start: 2627785

End: 2629338

Strand: Reverse

Name: trkH-2 [H]

Synonym: RD1_2756

Alternate gene names: 110679967

Gene position: 2629338-2627785 (Counterclockwise)

Preceding gene: 110679968

Following gene: 110679966

Centisome position: 63.62

GC content: 60.1

Gene sequence:

>1554_bases
ATGTCACGCGCTGCTCACAAAACGCCCCGCAAACCCCTGTCGGCCTACCTGCTGGATCAACAGCTGTTTGTGCTGATCTT
TGGTCTGGCCGCGTTCTCCATGATCATCCCCGCGCTGCACAGCGGGGCGACGCGTTCTTTGGAAACCTCGCGGGCGTTTT
TCTACACGGGCCTCTTCGGGATTGTGATTTTTGCGATGATCGTCATTGCCCAGACCGGGCGCACGCCCAGACATGGGGTG
CTCGGAAACCTCATGTCGATTTTCGCGACATTCGTGTTTCTGCCTGCCTTTTTGGCTCTGCCGCTTTATGAAAGCCTTCA
GACCACGCGTTTTCTCAACGCCTATGTCGAGATGGTGAGTGCGATCACGACCACGGGCGCAACGGTCTTTGATGACCCCT
CCCGCTTGAACAACACGCTTCATTTGTGGCGCGCGCAGGTTGCCTGGATGGGGGGCGTGATGATGTGGATCGCGGCGTCG
GCCATTCTTGCACCGCTCAATCTGGGCGGGTTTGAGGTCACGGCCCAAGCGGAACCCGGCCAGCGCGAAAGCCGTTTTGG
CGAGCTCGACAAGACCAACCCGCGCGAGAAACTGATGCGGATTGTGGTGGCGCTGGTGCCGATTTACGTCAGTCTCACGC
TGCTGCTCTGGGTGCTCTTGCTGATCAGCGGGGATCCGTCCCTCGTCGCGCTGACGCATGCGATGTCGATCATGTCAACG
TCGGGGATTTCTGCCATCGGCGGGCTTGAGGGCAGTGGCTCGGGGCTCACGGGCGAGGTGCTGATGCTGCTGTTCATGCT
GTTTGCGCTGTCGCGGCTGACGTTTTCCTCGGACACGGTGACGGCCACGCAGGGCGGTATCCAGACCGACCCCGAGTTCC
GCCTTGGCATGCTGATCGTGATCGGCGTGCCACTCGTGCTGTTTTTGCGCCACTGGATCGGTGCCTTTGATGTGGCCGCC
GAAGATGACTTCTGGTTGGCGATACGTGCCCTCTGGGGGTCGGTTTTCACGGTGATGTCCTTTCTGACGACGACCGGTTT
TGCCAGCGCGGACTGGGCGCAGGCGCAGGCGTGGTCCGGTCTTGAGACACCCGGTCTGATCCTGATGGGGCTGGCGCTGA
TGGGGGGCGGGGTTGCAACGACCGCAGGCGGTGTGAAACTGTTGCGCGTCTTTGCACTCTATCTCAACGGAAAACGCGAG
CTTGAGCGGCTGGTGCATCCCTCCTCGGTGAGCCGCGCAGGAAAGGAGAGCCGTCGCTTACAGCGAAACGGGGCCTTCAT
CGCATGGATTTTCTTCATGCTTTTTGCCATGACGATGGCTGCCTTGACGCTGTTGTTTGCCCTTTTCGGCGTCGCTTTCG
AGGATGCGCTCGTGCTCAGCATTGCGGGCCTGTCCACCACCGGCCCCTTGTTGAACCTTGCCACGGAAACGCCGATTTCA
CTGGCCGAACTGGGACCATATGCGAAATCCGTGTTCTGTGCGGCGATGGTTCTGGGGCGTTTGGAAACCCTTGCGATCAT
CGCGCTTTTGACGCCGGATTTATGGCGCAGTTGA

Upstream 100 bases:

>100_bases
CGCATTGACGAAGGCGATATCGTCGCCATCTTTGCCCTTGCCGAGGACGTGCCCGAAGTTGAACGGTTGATGCAAGTCTC
GATCGACTTTTTCTGATCCG

Downstream 100 bases:

>100_bases
GCGATTGAACGGTTAGGTCCGTAACGGACTGTTTTTAGGGCTGGAAACTCCGGGAACGGGGCTTCATAATCACGTCGAGG
GACGAGTTCGATCTGCGGGC

Product: Trk system potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MSRAAHKTPRKPLSAYLLDQQLFVLIFGLAAFSMIIPALHSGATRSLETSRAFFYTGLFGIVIFAMIVIAQTGRTPRHGV
LGNLMSIFATFVFLPAFLALPLYESLQTTRFLNAYVEMVSAITTTGATVFDDPSRLNNTLHLWRAQVAWMGGVMMWIAAS
AILAPLNLGGFEVTAQAEPGQRESRFGELDKTNPREKLMRIVVALVPIYVSLTLLLWVLLLISGDPSLVALTHAMSIMST
SGISAIGGLEGSGSGLTGEVLMLLFMLFALSRLTFSSDTVTATQGGIQTDPEFRLGMLIVIGVPLVLFLRHWIGAFDVAA
EDDFWLAIRALWGSVFTVMSFLTTTGFASADWAQAQAWSGLETPGLILMGLALMGGGVATTAGGVKLLRVFALYLNGKRE
LERLVHPSSVSRAGKESRRLQRNGAFIAWIFFMLFAMTMAALTLLFALFGVAFEDALVLSIAGLSTTGPLLNLATETPIS
LAELGPYAKSVFCAAMVLGRLETLAIIALLTPDLWRS

Sequences:

>Translated_517_residues
MSRAAHKTPRKPLSAYLLDQQLFVLIFGLAAFSMIIPALHSGATRSLETSRAFFYTGLFGIVIFAMIVIAQTGRTPRHGV
LGNLMSIFATFVFLPAFLALPLYESLQTTRFLNAYVEMVSAITTTGATVFDDPSRLNNTLHLWRAQVAWMGGVMMWIAAS
AILAPLNLGGFEVTAQAEPGQRESRFGELDKTNPREKLMRIVVALVPIYVSLTLLLWVLLLISGDPSLVALTHAMSIMST
SGISAIGGLEGSGSGLTGEVLMLLFMLFALSRLTFSSDTVTATQGGIQTDPEFRLGMLIVIGVPLVLFLRHWIGAFDVAA
EDDFWLAIRALWGSVFTVMSFLTTTGFASADWAQAQAWSGLETPGLILMGLALMGGGVATTAGGVKLLRVFALYLNGKRE
LERLVHPSSVSRAGKESRRLQRNGAFIAWIFFMLFAMTMAALTLLFALFGVAFEDALVLSIAGLSTTGPLLNLATETPIS
LAELGPYAKSVFCAAMVLGRLETLAIIALLTPDLWRS
>Mature_516_residues
SRAAHKTPRKPLSAYLLDQQLFVLIFGLAAFSMIIPALHSGATRSLETSRAFFYTGLFGIVIFAMIVIAQTGRTPRHGVL
GNLMSIFATFVFLPAFLALPLYESLQTTRFLNAYVEMVSAITTTGATVFDDPSRLNNTLHLWRAQVAWMGGVMMWIAASA
ILAPLNLGGFEVTAQAEPGQRESRFGELDKTNPREKLMRIVVALVPIYVSLTLLLWVLLLISGDPSLVALTHAMSIMSTS
GISAIGGLEGSGSGLTGEVLMLLFMLFALSRLTFSSDTVTATQGGIQTDPEFRLGMLIVIGVPLVLFLRHWIGAFDVAAE
DDFWLAIRALWGSVFTVMSFLTTTGFASADWAQAQAWSGLETPGLILMGLALMGGGVATTAGGVKLLRVFALYLNGKREL
ERLVHPSSVSRAGKESRRLQRNGAFIAWIFFMLFAMTMAALTLLFALFGVAFEDALVLSIAGLSTTGPLLNLATETPISL
AELGPYAKSVFCAAMVLGRLETLAIIALLTPDLWRS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=428, Percent_Identity=30.1401869158879, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI48994987, Length=383, Percent_Identity=27.154046997389, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 55804; Mature: 55672

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAAHKTPRKPLSAYLLDQQLFVLIFGLAAFSMIIPALHSGATRSLETSRAFFYTGLFG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IVIFAMIVIAQTGRTPRHGVLGNLMSIFATFVFLPAFLALPLYESLQTTRFLNAYVEMVS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AITTTGATVFDDPSRLNNTLHLWRAQVAWMGGVMMWIAASAILAPLNLGGFEVTAQAEPG
HHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
QRESRFGELDKTNPREKLMRIVVALVPIYVSLTLLLWVLLLISGDPSLVALTHAMSIMST
CHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SGISAIGGLEGSGSGLTGEVLMLLFMLFALSRLTFSSDTVTATQGGIQTDPEFRLGMLIV
CCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHH
IGVPLVLFLRHWIGAFDVAAEDDFWLAIRALWGSVFTVMSFLTTTGFASADWAQAQAWSG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC
LETPGLILMGLALMGGGVATTAGGVKLLRVFALYLNGKRELERLVHPSSVSRAGKESRRL
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
QRNGAFIAWIFFMLFAMTMAALTLLFALFGVAFEDALVLSIAGLSTTGPLLNLATETPIS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCC
LAELGPYAKSVFCAAMVLGRLETLAIIALLTPDLWRS
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure 
SRAAHKTPRKPLSAYLLDQQLFVLIFGLAAFSMIIPALHSGATRSLETSRAFFYTGLFG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IVIFAMIVIAQTGRTPRHGVLGNLMSIFATFVFLPAFLALPLYESLQTTRFLNAYVEMVS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AITTTGATVFDDPSRLNNTLHLWRAQVAWMGGVMMWIAASAILAPLNLGGFEVTAQAEPG
HHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
QRESRFGELDKTNPREKLMRIVVALVPIYVSLTLLLWVLLLISGDPSLVALTHAMSIMST
CHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SGISAIGGLEGSGSGLTGEVLMLLFMLFALSRLTFSSDTVTATQGGIQTDPEFRLGMLIV
CCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHH
IGVPLVLFLRHWIGAFDVAAEDDFWLAIRALWGSVFTVMSFLTTTGFASADWAQAQAWSG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC
LETPGLILMGLALMGGGVATTAGGVKLLRVFALYLNGKRELERLVHPSSVSRAGKESRRL
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
QRNGAFIAWIFFMLFAMTMAALTLLFALFGVAFEDALVLSIAGLSTTGPLLNLATETPIS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCC
LAELGPYAKSVFCAAMVLGRLETLAIIALLTPDLWRS
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]