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The map label for this gene is trkA [H]

Identifier: 110679968

GI number: 110679968

Start: 2629343

End: 2630719

Strand: Reverse

Name: trkA [H]

Synonym: RD1_2757

Alternate gene names: 110679968

Gene position: 2630719-2629343 (Counterclockwise)

Preceding gene: 110679971

Following gene: 110679967

Centisome position: 63.65

GC content: 61.95

Gene sequence:

>1377_bases
ATGAAGGTCATCATCTGCGGTGCCGGTCAGGTGGGCTGGCAGATCGCGCGGCATCTTTCAGGCGAACGCAATGACGTGAC
CGTCGTGGACAGCAACCCTGACCTCGTGCGGCGCGCAACGGATTCGCTGGATGTGCAGGGGATCGCAGGTTTTGCGAGCT
ACCCCGACGTGCTGGCCCGTGCCGGGGCGGAAGATGCGGAAATGATCATCGCCGCGACCCATTCGGATGAAGTCAACATG
GTGACGTGCCAGATTGCCCATTCGGTTTTCGGCGTTAATCGCAAGATCGCGCGTCTGCGCAGCCAGTCCTATCTGGAGGC
GATATACTCCGACCTTTACAGGCGCGATCACATGCCGATCGACGTGGTGATCAGCCCCGAAAGGGAAGTCGCCTCCGCCG
CCCTGCAGCGTCTGTCTGCGCCAGCGGCCTTTGACACCGAAGTCTTCATGGACGGCAAGGCGCATCTGCTGGGCATCACC
ATCGAAGAGGAATGCCCGGTGGTGAACACGCCGCTGCGGCAACTCACCGATCTGTTTTCGACGCTGCGCGCAACGGTCGT
TGGCGTGCGGCGCGAAGGCAGCCTGTTTGCGCCCGAGGCCAAGGACCAGCTTTTTGTCGGGGATGACTGCTACGTCTTTT
GCCACGTCGCGGATATTGCGCGAACGATGGAAATCTTTGGCAAGAAACAGTCAAAGCAGGAACGCGTGGTGCTTGTGGGC
GGCGGCAACGTTGGTCTTGCGGTGGCCCAGGCCCTTGAGCAGCGCGCCAAACGCGTGCGCACCAAGGTCATTGAAAAAAA
CCGCCACTGCGCCGAACGCGCCGCCGAGGCGTTGGAGCGTACCATCGTGCTGAATGGCGATGGTCTGGATTCAGGGCTCT
TGGCGGAGGCGGGCATCGCGCGGGCGGATGCGATGCTGGCGATCACCGATGACGACAAGACCAACATGCTGGCCTGTGTG
CGTGCCAAATCGGAGGGCTGCCCCTATGTGATCGCGCTGATCAATGACCCGACCCTCGTGCCGCTCATGGGGCCGTTGGG
CATTGACGCCTACATCAACCCACGCGCCACGACGGTCAGCTCCATCCTGCGCCACATCCGGCACGGCAGGGTGCGCGCGG
TCTATTCGGTCGGCGACGCAGAGGCCGAAGTGATCGAAGCCGAGGTGCTGTCGACCTCGCCGCTGGCGGGCAGCCGGATT
GCAGATATCGAATTTCCCGAAGGTGTGCTGGTCGGCGCGGTGCGCAAGGGTGACAAGATCATCCGCCCCATGGGCAGCAC
GCGCATTGACGAAGGCGATATCGTCGCCATCTTTGCCCTTGCCGAGGACGTGCCCGAAGTTGAACGGTTGATGCAAGTCT
CGATCGACTTTTTCTGA

Upstream 100 bases:

>100_bases
ATAAAATGCCCGCTTTGGCTGCCCAAGACAATTGAATTGACCGTGTGCGGGCCATCTGCCATTCAGAAAGCCTTAGGCAT
GCCCTGAAGGACACGTAAAC

Downstream 100 bases:

>100_bases
TCCGATGTCACGCGCTGCTCACAAAACGCCCCGCAAACCCCTGTCGGCCTACCTGCTGGATCAACAGCTGTTTGTGCTGA
TCTTTGGTCTGGCCGCGTTC

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKVIICGAGQVGWQIARHLSGERNDVTVVDSNPDLVRRATDSLDVQGIAGFASYPDVLARAGAEDAEMIIAATHSDEVNM
VTCQIAHSVFGVNRKIARLRSQSYLEAIYSDLYRRDHMPIDVVISPEREVASAALQRLSAPAAFDTEVFMDGKAHLLGIT
IEEECPVVNTPLRQLTDLFSTLRATVVGVRREGSLFAPEAKDQLFVGDDCYVFCHVADIARTMEIFGKKQSKQERVVLVG
GGNVGLAVAQALEQRAKRVRTKVIEKNRHCAERAAEALERTIVLNGDGLDSGLLAEAGIARADAMLAITDDDKTNMLACV
RAKSEGCPYVIALINDPTLVPLMGPLGIDAYINPRATTVSSILRHIRHGRVRAVYSVGDAEAEVIEAEVLSTSPLAGSRI
ADIEFPEGVLVGAVRKGDKIIRPMGSTRIDEGDIVAIFALAEDVPEVERLMQVSIDFF

Sequences:

>Translated_458_residues
MKVIICGAGQVGWQIARHLSGERNDVTVVDSNPDLVRRATDSLDVQGIAGFASYPDVLARAGAEDAEMIIAATHSDEVNM
VTCQIAHSVFGVNRKIARLRSQSYLEAIYSDLYRRDHMPIDVVISPEREVASAALQRLSAPAAFDTEVFMDGKAHLLGIT
IEEECPVVNTPLRQLTDLFSTLRATVVGVRREGSLFAPEAKDQLFVGDDCYVFCHVADIARTMEIFGKKQSKQERVVLVG
GGNVGLAVAQALEQRAKRVRTKVIEKNRHCAERAAEALERTIVLNGDGLDSGLLAEAGIARADAMLAITDDDKTNMLACV
RAKSEGCPYVIALINDPTLVPLMGPLGIDAYINPRATTVSSILRHIRHGRVRAVYSVGDAEAEVIEAEVLSTSPLAGSRI
ADIEFPEGVLVGAVRKGDKIIRPMGSTRIDEGDIVAIFALAEDVPEVERLMQVSIDFF
>Mature_458_residues
MKVIICGAGQVGWQIARHLSGERNDVTVVDSNPDLVRRATDSLDVQGIAGFASYPDVLARAGAEDAEMIIAATHSDEVNM
VTCQIAHSVFGVNRKIARLRSQSYLEAIYSDLYRRDHMPIDVVISPEREVASAALQRLSAPAAFDTEVFMDGKAHLLGIT
IEEECPVVNTPLRQLTDLFSTLRATVVGVRREGSLFAPEAKDQLFVGDDCYVFCHVADIARTMEIFGKKQSKQERVVLVG
GGNVGLAVAQALEQRAKRVRTKVIEKNRHCAERAAEALERTIVLNGDGLDSGLLAEAGIARADAMLAITDDDKTNMLACV
RAKSEGCPYVIALINDPTLVPLMGPLGIDAYINPRATTVSSILRHIRHGRVRAVYSVGDAEAEVIEAEVLSTSPLAGSRI
ADIEFPEGVLVGAVRKGDKIIRPMGSTRIDEGDIVAIFALAEDVPEVERLMQVSIDFF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=462, Percent_Identity=35.4978354978355, Blast_Score=266, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49628; Mature: 49628

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIICGAGQVGWQIARHLSGERNDVTVVDSNPDLVRRATDSLDVQGIAGFASYPDVLAR
CEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHH
AGAEDAEMIIAATHSDEVNMVTCQIAHSVFGVNRKIARLRSQSYLEAIYSDLYRRDHMPI
CCCCCCEEEEEEECCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCE
DVVISPEREVASAALQRLSAPAAFDTEVFMDGKAHLLGITIEEECPVVNTPLRQLTDLFS
EEEECCCHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHH
TLRATVVGVRREGSLFAPEAKDQLFVGDDCYVFCHVADIARTMEIFGKKQSKQERVVLVG
HHHHHHHEEECCCCEECCCCCCCEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEEEE
GGNVGLAVAQALEQRAKRVRTKVIEKNRHCAERAAEALERTIVLNGDGLDSGLLAEAGIA
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHCCCC
RADAMLAITDDDKTNMLACVRAKSEGCPYVIALINDPTLVPLMGPLGIDAYINPRATTVS
CCCEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCEEEEEECCCCCCEEECCCHHHHH
SILRHIRHGRVRAVYSVGDAEAEVIEAEVLSTSPLAGSRIADIEFPEGVLVGAVRKGDKI
HHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEECCCCCE
IRPMGSTRIDEGDIVAIFALAEDVPEVERLMQVSIDFF
ECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVIICGAGQVGWQIARHLSGERNDVTVVDSNPDLVRRATDSLDVQGIAGFASYPDVLAR
CEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHH
AGAEDAEMIIAATHSDEVNMVTCQIAHSVFGVNRKIARLRSQSYLEAIYSDLYRRDHMPI
CCCCCCEEEEEEECCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCE
DVVISPEREVASAALQRLSAPAAFDTEVFMDGKAHLLGITIEEECPVVNTPLRQLTDLFS
EEEECCCHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHH
TLRATVVGVRREGSLFAPEAKDQLFVGDDCYVFCHVADIARTMEIFGKKQSKQERVVLVG
HHHHHHHEEECCCCEECCCCCCCEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEEEE
GGNVGLAVAQALEQRAKRVRTKVIEKNRHCAERAAEALERTIVLNGDGLDSGLLAEAGIA
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHCCCC
RADAMLAITDDDKTNMLACVRAKSEGCPYVIALINDPTLVPLMGPLGIDAYINPRATTVS
CCCEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCEEEEEECCCCCCEEECCCHHHHH
SILRHIRHGRVRAVYSVGDAEAEVIEAEVLSTSPLAGSRIADIEFPEGVLVGAVRKGDKI
HHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEECCCCCE
IRPMGSTRIDEGDIVAIFALAEDVPEVERLMQVSIDFF
ECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]