Click here to switch to the map view.

The map label for this gene is acy [H]

Identifier: 110679963

GI number: 110679963

Start: 2623092

End: 2625557

Strand: Direct

Name: acy [H]

Synonym: RD1_2752

Alternate gene names: 110679963

Gene position: 2623092-2625557 (Clockwise)

Preceding gene: 110679961

Following gene: 110679964

Centisome position: 63.47

GC content: 61.35

Gene sequence:

>2466_bases
ATGGCACAGGTCTTTACATGGCTATTGCGGATCGCGGGCACGCTGGTTGCGCTCATCGTGCTGGCCATTGTGATGATGTA
TTACCTCGGCACACGCTCCCTGCCCGACTACGATGACGTGCTGGACGTGCCCTACCTGAATGCCCCGGTCGAGATCGTGC
GCGACAATGCCAACGTGCCACATATCTTCGGCAGCAATGACGAAGACGTGTTCTACGCCCTAGGGTACGCACATGCGCAG
GACCGTCTGTGGCAAATGACACTGATGCGGCGCACCGCGCAGGGGCGTCTGTCGGAAGTCTTTGGCAGGGAAACCCTTGA
TATTGACAACATCATGCGTCGGCTGGACATCTATCCGCTGGCCGTGGCCTCGCTTGAGGCGCAGGATGAAAGGACGATGC
GCATTTTACGCGCCTATGCCACGGGCGTGAATGCCCGGCTTGATCAGGTGAATGACGAAGCATTGGGTCGCGGCGCGCCT
GAAATGTTCCTGTTCAATGCCCCCGTCGCGCCCTGGCGCCCGGCGGACTCCATGGCCATCATCAAGCTGATGGGTGTACG
TCTCGCGCGCCATCTGGATACCGAAGTGATGCGCGCGCGCATGATCAAGGCTCTGCCAAATCCCGAGCGCATCATCGACA
TCCTGCCCGATGCGCCCGGCACGGGAACCGCCGCCCTGCCGGAATACGCGCATCTGCTGGGCCCGCCTGCGCATTTCGCT
GGCCGTTCCGACATTCACACGCACCCTTTGTCACCTTTTGCCCCGGCTGAAATGGCGGGCGCATCGAACGTCTGGGCCGC
CGCGCCCTCACGCTCCGCCTCCGGGGGCACGCTTCTGGCCAATGACCCGCATCTTGGTTTTTCCGCACCCGGTATCTGGT
ATCTGGCGCGGCTTGAGTTGCAATCAGGTGGCGTGATCGGCGGGACCATTCCGGGTATGCCGATTGTTCTGACCGGACGC
AGCGACAGGCTGGGCTGGGGTCTGACCTCTGCCGGGATGGACGATCAGGACCTCTACCTCGAAGAGCTGCACCCCGAGAA
CAAGGACGAATACCGCACGCCATCAGGCTTCAAGAAGCTGACGTCCCGCAAGTCGATCATCAACATAAAGGACGAACCCC
CGGTCACGATCACCATGCACTGGACCGACAATGGCCCGGTGTTGCCGGGCCGGTTGTATAACCTCGGTGATGTGATGCAG
CCCGGCCATGCGATATCCCTGAGCTGGACGCTGCTGAGCCCGAATGACACCTCCATGATGGCCGCTCTGCGCCTTATGGA
GGCGCAATCGGTGGAGGAAGGCTTTGCCCTGATGGAAGACTACATCGCCCCGGCGCAGAACCTGATGCTGGTGGACGCCG
AGAACATCGGAATGAAGATGATCGGCGCCATGCCGCGCCGCGATGCCCGCCACGAGACGCAAGGCCGCCTGCCCAGCTAT
GGCTGGAAAGAGGAGAACCGCTGGCAGGGCACCTTTCCTTATGCCTCGAACCCTGAGTTCATTGCCCCCGCGGGCGGTAT
TCTGGGCAATACGAACAACAAGGTCGTCGAGCGCCCCTTCCCCAACCATGTATCGTTTGACTGGGGGGACACGCAGCGGG
TCAAACGGTGGCAAAGGCTGATGCAGGCGCGTGAAGTACACACTCGGGACAGCTTCATAGAGGCACAGCTCGATGCGGTC
AGTACATCCGCGCGCACATTGCTCGCCCTGATCGGCACCGAGCTTTGGTTTACCGGCGAGGCGGCCGAAGAAGGCACCCC
GCTGCGCCGCCGCCAGCGCGCTCTGTCCCTGCTGGCGGAATGGTCCGGCGAAATGAACGAACACATGCCGGAACCCTTGA
TCTATTCTGCATGGGTGCGCAGCCTGCAATTGCGCATGGTGCAGGATGAACTTGGACCGCTTGCGGTTGAATTGACCCAT
GTGGAACCGCTGTTCATCGAACGGGCCTTCCGCGATGTGGAGGGCGCTTCGGTCTGGTGCGATGTCATCCAGTCCCAACC
CATTGAGACCTGCGCAGATATGGCGCGGCTGGCGTTGGATGATGCGCTGATCTGGATCGGGGAAAACTGGGGCCAATCCC
TCGAAACCCTGCGTTGGGGGGATGCGCATCAGGCCACGCATGATCATCCTGTGCTGGGCGACGTGCCGCTGTTGCGCTAT
TTTGTGAACATCCGCCAGTCGACCAATGGCGGCGACAATACGCTGCAACGGGGGCTGACGCGTGGATATGGCGACAACCC
TTTCGCCAATGTGCATGGGGCGGGGTATCGCGGGGTCTATGATTTCGCCGATCCCGACAGTTCGGTATTCGTCACGTCAA
CCGGGCAATCGGGGCATTTCCTGTCGCGTCATTACGATGATATGGCGCAGCTTTGGCGGCGGGGCGAATACATCCCGATG
TCGCTGGACGAAGACCTTGCACGGGCGGGCGCTGTTGGGGTCACGACGCTTCGGCCTGCCCCGTAA

Upstream 100 bases:

>100_bases
TTTGAAGCCCCCTTTTGGGTGTTGCGTTACCTTGCCCTCCTACCTAACAGTCAGAGGTCTAGGGTCAATTCATTCGAACC
GGTTTCGACACGAGGGCGTC

Downstream 100 bases:

>100_bases
ATGGCCCGCGTCATCCTGTTCAACAAACCCTTCGGGGTGCTGTCGCAATTCACCGACAAGGGCAGCGAAGGATCACCGCG
CCCGACGCTTTCGGCCTTCA

Product: penicillin acylase, putative

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 821; Mature: 820

Protein sequence:

>821_residues
MAQVFTWLLRIAGTLVALIVLAIVMMYYLGTRSLPDYDDVLDVPYLNAPVEIVRDNANVPHIFGSNDEDVFYALGYAHAQ
DRLWQMTLMRRTAQGRLSEVFGRETLDIDNIMRRLDIYPLAVASLEAQDERTMRILRAYATGVNARLDQVNDEALGRGAP
EMFLFNAPVAPWRPADSMAIIKLMGVRLARHLDTEVMRARMIKALPNPERIIDILPDAPGTGTAALPEYAHLLGPPAHFA
GRSDIHTHPLSPFAPAEMAGASNVWAAAPSRSASGGTLLANDPHLGFSAPGIWYLARLELQSGGVIGGTIPGMPIVLTGR
SDRLGWGLTSAGMDDQDLYLEELHPENKDEYRTPSGFKKLTSRKSIINIKDEPPVTITMHWTDNGPVLPGRLYNLGDVMQ
PGHAISLSWTLLSPNDTSMMAALRLMEAQSVEEGFALMEDYIAPAQNLMLVDAENIGMKMIGAMPRRDARHETQGRLPSY
GWKEENRWQGTFPYASNPEFIAPAGGILGNTNNKVVERPFPNHVSFDWGDTQRVKRWQRLMQAREVHTRDSFIEAQLDAV
STSARTLLALIGTELWFTGEAAEEGTPLRRRQRALSLLAEWSGEMNEHMPEPLIYSAWVRSLQLRMVQDELGPLAVELTH
VEPLFIERAFRDVEGASVWCDVIQSQPIETCADMARLALDDALIWIGENWGQSLETLRWGDAHQATHDHPVLGDVPLLRY
FVNIRQSTNGGDNTLQRGLTRGYGDNPFANVHGAGYRGVYDFADPDSSVFVTSTGQSGHFLSRHYDDMAQLWRRGEYIPM
SLDEDLARAGAVGVTTLRPAP

Sequences:

>Translated_821_residues
MAQVFTWLLRIAGTLVALIVLAIVMMYYLGTRSLPDYDDVLDVPYLNAPVEIVRDNANVPHIFGSNDEDVFYALGYAHAQ
DRLWQMTLMRRTAQGRLSEVFGRETLDIDNIMRRLDIYPLAVASLEAQDERTMRILRAYATGVNARLDQVNDEALGRGAP
EMFLFNAPVAPWRPADSMAIIKLMGVRLARHLDTEVMRARMIKALPNPERIIDILPDAPGTGTAALPEYAHLLGPPAHFA
GRSDIHTHPLSPFAPAEMAGASNVWAAAPSRSASGGTLLANDPHLGFSAPGIWYLARLELQSGGVIGGTIPGMPIVLTGR
SDRLGWGLTSAGMDDQDLYLEELHPENKDEYRTPSGFKKLTSRKSIINIKDEPPVTITMHWTDNGPVLPGRLYNLGDVMQ
PGHAISLSWTLLSPNDTSMMAALRLMEAQSVEEGFALMEDYIAPAQNLMLVDAENIGMKMIGAMPRRDARHETQGRLPSY
GWKEENRWQGTFPYASNPEFIAPAGGILGNTNNKVVERPFPNHVSFDWGDTQRVKRWQRLMQAREVHTRDSFIEAQLDAV
STSARTLLALIGTELWFTGEAAEEGTPLRRRQRALSLLAEWSGEMNEHMPEPLIYSAWVRSLQLRMVQDELGPLAVELTH
VEPLFIERAFRDVEGASVWCDVIQSQPIETCADMARLALDDALIWIGENWGQSLETLRWGDAHQATHDHPVLGDVPLLRY
FVNIRQSTNGGDNTLQRGLTRGYGDNPFANVHGAGYRGVYDFADPDSSVFVTSTGQSGHFLSRHYDDMAQLWRRGEYIPM
SLDEDLARAGAVGVTTLRPAP
>Mature_820_residues
AQVFTWLLRIAGTLVALIVLAIVMMYYLGTRSLPDYDDVLDVPYLNAPVEIVRDNANVPHIFGSNDEDVFYALGYAHAQD
RLWQMTLMRRTAQGRLSEVFGRETLDIDNIMRRLDIYPLAVASLEAQDERTMRILRAYATGVNARLDQVNDEALGRGAPE
MFLFNAPVAPWRPADSMAIIKLMGVRLARHLDTEVMRARMIKALPNPERIIDILPDAPGTGTAALPEYAHLLGPPAHFAG
RSDIHTHPLSPFAPAEMAGASNVWAAAPSRSASGGTLLANDPHLGFSAPGIWYLARLELQSGGVIGGTIPGMPIVLTGRS
DRLGWGLTSAGMDDQDLYLEELHPENKDEYRTPSGFKKLTSRKSIINIKDEPPVTITMHWTDNGPVLPGRLYNLGDVMQP
GHAISLSWTLLSPNDTSMMAALRLMEAQSVEEGFALMEDYIAPAQNLMLVDAENIGMKMIGAMPRRDARHETQGRLPSYG
WKEENRWQGTFPYASNPEFIAPAGGILGNTNNKVVERPFPNHVSFDWGDTQRVKRWQRLMQAREVHTRDSFIEAQLDAVS
TSARTLLALIGTELWFTGEAAEEGTPLRRRQRALSLLAEWSGEMNEHMPEPLIYSAWVRSLQLRMVQDELGPLAVELTHV
EPLFIERAFRDVEGASVWCDVIQSQPIETCADMARLALDDALIWIGENWGQSLETLRWGDAHQATHDHPVLGDVPLLRYF
VNIRQSTNGGDNTLQRGLTRGYGDNPFANVHGAGYRGVYDFADPDSSVFVTSTGQSGHFLSRHYDDMAQLWRRGEYIPMS
LDEDLARAGAVGVTTLRPAP

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 91230; Mature: 91099

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVFTWLLRIAGTLVALIVLAIVMMYYLGTRSLPDYDDVLDVPYLNAPVEIVRDNANVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHEEECCCCCC
HIFGSNDEDVFYALGYAHAQDRLWQMTLMRRTAQGRLSEVFGRETLDIDNIMRRLDIYPL
EEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
AVASLEAQDERTMRILRAYATGVNARLDQVNDEALGRGAPEMFLFNAPVAPWRPADSMAI
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHCCCCCCEEEEECCCCCCCCCCHHHH
IKLMGVRLARHLDTEVMRARMIKALPNPERIIDILPDAPGTGTAALPEYAHLLGPPAHFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCCCHHHHHHHCCCCHHHC
GRSDIHTHPLSPFAPAEMAGASNVWAAAPSRSASGGTLLANDPHLGFSAPGIWYLARLEL
CCCCCCCCCCCCCCCHHHCCCCCCEECCCCCCCCCCEEEECCCCCCCCCCCEEEEEEEEE
QSGGVIGGTIPGMPIVLTGRSDRLGWGLTSAGMDDQDLYLEELHPENKDEYRTPSGFKKL
CCCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
TSRKSIINIKDEPPVTITMHWTDNGPVLPGRLYNLGDVMQPGHAISLSWTLLSPNDTSMM
HCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHCCCCCEEEEEEEEECCCCHHHH
AALRLMEAQSVEEGFALMEDYIAPAQNLMLVDAENIGMKMIGAMPRRDARHETQGRLPSY
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCCHHHHCCCCCC
GWKEENRWQGTFPYASNPEFIAPAGGILGNTNNKVVERPFPNHVSFDWGDTQRVKRWQRL
CCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
MQAREVHTRDSFIEAQLDAVSTSARTLLALIGTELWFTGEAAEEGTPLRRRQRALSLLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHH
WSGEMNEHMPEPLIYSAWVRSLQLRMVQDELGPLAVELTHVEPLFIERAFRDVEGASVWC
HCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHH
DVIQSQPIETCADMARLALDDALIWIGENWGQSLETLRWGDAHQATHDHPVLGDVPLLRY
HHHHCCCHHHHHHHHHHHHHCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
FVNIRQSTNGGDNTLQRGLTRGYGDNPFANVHGAGYRGVYDFADPDSSVFVTSTGQSGHF
HHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCH
LSRHYDDMAQLWRRGEYIPMSLDEDLARAGAVGVTTLRPAP
HHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AQVFTWLLRIAGTLVALIVLAIVMMYYLGTRSLPDYDDVLDVPYLNAPVEIVRDNANVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHEEECCCCCC
HIFGSNDEDVFYALGYAHAQDRLWQMTLMRRTAQGRLSEVFGRETLDIDNIMRRLDIYPL
EEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
AVASLEAQDERTMRILRAYATGVNARLDQVNDEALGRGAPEMFLFNAPVAPWRPADSMAI
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHCCCCCCEEEEECCCCCCCCCCHHHH
IKLMGVRLARHLDTEVMRARMIKALPNPERIIDILPDAPGTGTAALPEYAHLLGPPAHFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCCCHHHHHHHCCCCHHHC
GRSDIHTHPLSPFAPAEMAGASNVWAAAPSRSASGGTLLANDPHLGFSAPGIWYLARLEL
CCCCCCCCCCCCCCCHHHCCCCCCEECCCCCCCCCCEEEECCCCCCCCCCCEEEEEEEEE
QSGGVIGGTIPGMPIVLTGRSDRLGWGLTSAGMDDQDLYLEELHPENKDEYRTPSGFKKL
CCCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
TSRKSIINIKDEPPVTITMHWTDNGPVLPGRLYNLGDVMQPGHAISLSWTLLSPNDTSMM
HCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHCCCCCEEEEEEEEECCCCHHHH
AALRLMEAQSVEEGFALMEDYIAPAQNLMLVDAENIGMKMIGAMPRRDARHETQGRLPSY
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCCHHHHCCCCCC
GWKEENRWQGTFPYASNPEFIAPAGGILGNTNNKVVERPFPNHVSFDWGDTQRVKRWQRL
CCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
MQAREVHTRDSFIEAQLDAVSTSARTLLALIGTELWFTGEAAEEGTPLRRRQRALSLLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHH
WSGEMNEHMPEPLIYSAWVRSLQLRMVQDELGPLAVELTHVEPLFIERAFRDVEGASVWC
HCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHH
DVIQSQPIETCADMARLALDDALIWIGENWGQSLETLRWGDAHQATHDHPVLGDVPLLRY
HHHHCCCHHHHHHHHHHHHHCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
FVNIRQSTNGGDNTLQRGLTRGYGDNPFANVHGAGYRGVYDFADPDSSVFVTSTGQSGHF
HHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCH
LSRHYDDMAQLWRRGEYIPMSLDEDLARAGAVGVTTLRPAP
HHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]